IMP
Process View
aflatoxin metabolic process
The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "aflatoxin metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gstm1 | glutathione S-transferase, mu 1 | 0.194 | ||
| Gstt1 | glutathione S-transferase, theta 1 | 0.099 | ||
| Cbr1 | carbonyl reductase 1 | 0.070 | ||
| Selenbp1 | selenium binding protein 1 | 0.046 | ||
| Prdx6 | peroxiredoxin 6 | 0.043 | ||
| Gsto1 | glutathione S-transferase omega 1 | 0.034 | ||
| Ces1d | carboxylesterase 1D | 0.031 | ||
| Pgls | 6-phosphogluconolactonase | 0.027 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.027 | ||
| Cmbl | carboxymethylenebutenolidase-like (Pseudomonas) | 0.022 | ||
| Cyb5 | cytochrome b-5 | 0.020 | ||
| Tmem205 | transmembrane protein 205 | 0.017 | ||
| Gstk1 | glutathione S-transferase kappa 1 | 0.015 | ||
| Aox1 | aldehyde oxidase 1 | 0.013 | ||
| BC004004 | cDNA sequence BC004004 | 0.012 | ||
| Aldh1a1 | aldehyde dehydrogenase family 1, subfamily A1 | 0.011 | ||
| Eci1 | enoyl-Coenzyme A delta isomerase 1 | 0.011 | ||
| Chchd10 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 0.011 | ||
| Adh1 | alcohol dehydrogenase 1 (class I) | 0.010 |