IMP: Integrative Multi-species Prediction

Mus musculus

35 genes annotated in mouse

cell aging

An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell aging"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cell aging" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Pten	phosphatase and tensin homolog	0.999
Brca1	breast cancer 1	0.928
Apc	adenomatosis polyposis coli	0.928
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.848
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.801
Igh	immunoglobulin heavy chain complex	0.799
Bglap	bone gamma carboxyglutamate protein	0.771
Mdm2	transformed mouse 3T3 cell double minute 2	0.761
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.760	Yeast Mouse
Id3	inhibitor of DNA binding 3	0.715	Mouse
Trp63	transformation related protein 63	0.675
Id1	inhibitor of DNA binding 1	0.671	Mouse
Mapk14	mitogen-activated protein kinase 14	0.665	Human
Smad4	MAD homolog 4 (Drosophila)	0.624
Ahr	aryl-hydrocarbon receptor	0.604
Lmnb1	lamin B1	0.591	Fly
Braf	Braf transforming gene	0.563
Mdm4	transformed mouse 3T3 cell double minute 4	0.537
Tgfbr2	transforming growth factor, beta receptor II	0.513	Mouse
Brca2	breast cancer 2	0.474
Ccnd1	cyclin D1	0.467
Skil	SKI-like	0.445
Trp73	transformation related protein 73	0.423	Mouse
Dok1	docking protein 1	0.422
Pitx1	paired-like homeodomain transcription factor 1	0.349
Nos3	nitric oxide synthase 3, endothelial cell	0.321
Smad2	MAD homolog 2 (Drosophila)	0.266
Fgfr2	fibroblast growth factor receptor 2	0.261
Vhl	von Hippel-Lindau tumor suppressor	0.251
Hspa9	heat shock protein 9	0.237
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.234
Myl9	myosin, light polypeptide 9, regulatory	0.231
Msh2	mutS homolog 2 (E. coli)	0.230
Tbx3	T-box 3	0.222
Tcf3	transcription factor 3	0.219
Bcl2	B-cell leukemia/lymphoma 2	0.216
Bax	BCL2-associated X protein	0.200	Mouse
Vasp	vasodilator-stimulated phosphoprotein	0.200
Rnf2	ring finger protein 2	0.197
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.190
Bcl6	B-cell leukemia/lymphoma 6	0.179
Abi1	abl-interactor 1	0.178
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.176
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.167
Bak1	BCL2-antagonist/killer 1	0.164	Mouse
Emx1	empty spiracles homolog 1 (Drosophila)	0.162
Rb1	retinoblastoma 1	0.158
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.155
Smad3	MAD homolog 3 (Drosophila)	0.141
Ccnd2	cyclin D2	0.137
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.134
Tagln	transgelin	0.132	Yeast
Daxx	Fas death domain-associated protein	0.131
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.130
Atm	ataxia telangiectasia mutated homolog (human)	0.129	Human
Cd44	CD44 antigen	0.129
Nf1	neurofibromatosis 1	0.127
Tgfbr1	transforming growth factor, beta receptor I	0.121	Mouse
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.118
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.117
Nbn	nibrin	0.116
Smad7	MAD homolog 7 (Drosophila)	0.115
Tpm4	tropomyosin 4	0.114
Smad6	MAD homolog 6 (Drosophila)	0.108
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.105
Clock	circadian locomotor output cycles kaput	0.105
Pitx2	paired-like homeodomain transcription factor 2	0.104
Fzd1	frizzled homolog 1 (Drosophila)	0.101
Gab1	growth factor receptor bound protein 2-associated protein 1	0.100
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.099	Human
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.094
Shc1	src homology 2 domain-containing transforming protein C1	0.094
Egfr	epidermal growth factor receptor	0.091
Raf1	v-raf-leukemia viral oncogene 1	0.088
Fshr	follicle stimulating hormone receptor	0.088
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.085
Dll4	delta-like 4 (Drosophila)	0.085
Esr1	estrogen receptor 1 (alpha)	0.084
Atr	ataxia telangiectasia and Rad3 related	0.084	Human
Pfn1	profilin 1	0.083
Max	Max protein	0.082
Fgf8	fibroblast growth factor 8	0.081
Lif	leukemia inhibitory factor	0.080
Cry2	cryptochrome 2 (photolyase-like)	0.078
En1	engrailed 1	0.078
Immt	inner membrane protein, mitochondrial	0.077
Prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.077	Yeast
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.077	Mouse
Bmp5	bone morphogenetic protein 5	0.076
Cxadr	coxsackie virus and adenovirus receptor	0.076
Huwe1	HECT, UBA and WWE domain containing 1	0.075
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.074
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.074
Hoxa1	homeobox A1	0.074
Atf2	activating transcription factor 2	0.072
Mybl2	myeloblastosis oncogene-like 2	0.072
Cd40	CD40 antigen	0.071
Bmi1	Bmi1 polycomb ring finger oncogene	0.070
Runx1	runt related transcription factor 1	0.070
Tsc1	tuberous sclerosis 1	0.069
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.069
Acvr1	activin A receptor, type 1	0.068	Mouse
Ar	androgen receptor	0.068
Met	met proto-oncogene	0.068	Rat
E2f1	E2F transcription factor 1	0.067
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.067
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.065
Fst	follistatin	0.064
Grb2	growth factor receptor bound protein 2	0.063
Thbs1	thrombospondin 1	0.063
Cry1	cryptochrome 1 (photolyase-like)	0.062
Tcf4	transcription factor 4	0.061
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.061
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.061
Msx1	homeobox, msh-like 1	0.060
Cotl1	coactosin-like 1 (Dictyostelium)	0.058
Mapkapk2	MAP kinase-activated protein kinase 2	0.057	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.057
Hspd1	heat shock protein 1 (chaperonin)	0.056
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.054
Wnt3a	wingless-related MMTV integration site 3A	0.053
Rfwd2	ring finger and WD repeat domain 2	0.053
Lmna	lamin A	0.053	Human Zebrafish Fly
Rxra	retinoid X receptor alpha	0.052
Per2	period homolog 2 (Drosophila)	0.052
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.051
Ghr	growth hormone receptor	0.050
Fgfr1	fibroblast growth factor receptor 1	0.050
Foxo3	forkhead box O3	0.049
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.049
Rbl2	retinoblastoma-like 2	0.049
Tbk1	TANK-binding kinase 1	0.048
Msn	moesin	0.048
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.047
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.047
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.047
Hbb-b1	hemoglobin, beta adult major chain	0.047
Mylk	myosin, light polypeptide kinase	0.046
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.046
Fgfr3	fibroblast growth factor receptor 3	0.045
Acd	adrenocortical dysplasia	0.044
Tbx4	T-box 4	0.044	Mouse
Foxg1	forkhead box G1	0.044
Htt	huntingtin	0.044
Lyst	lysosomal trafficking regulator	0.044
Cdk4	cyclin-dependent kinase 4	0.043
Rbl1	retinoblastoma-like 1 (p107)	0.043
Cbl	Casitas B-lineage lymphoma	0.043
Lig4	ligase IV, DNA, ATP-dependent	0.043
Rhoc	ras homolog gene family, member C	0.042
Tbx1	T-box 1	0.042	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.042
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.042
Nodal	nodal	0.042
Cdk2	cyclin-dependent kinase 2	0.042
Vegfa	vascular endothelial growth factor A	0.040
Npas2	neuronal PAS domain protein 2	0.040
Ptp4a1	protein tyrosine phosphatase 4a1	0.040
Plk1	polo-like kinase 1 (Drosophila)	0.040
Fmn1	formin 1	0.039
Bcor	BCL6 interacting corepressor	0.039
Dbi	diazepam binding inhibitor	0.039
Cdh5	cadherin 5	0.039
Tcf19	transcription factor 19	0.039
Ptk2	PTK2 protein tyrosine kinase 2	0.039
Zfp187	zinc finger protein 187	0.039
Mmp9	matrix metallopeptidase 9	0.039
Phc1	polyhomeotic-like 1 (Drosophila)	0.039
Wwox	WW domain-containing oxidoreductase	0.038
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.038
Stat6	signal transducer and activator of transcription 6	0.038
Smn1	survival motor neuron 1	0.038
Tagln2	transgelin 2	0.038	Yeast
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.037
Ep300	E1A binding protein p300	0.037
Slc12a4	solute carrier family 12, member 4	0.037
Rhog	ras homolog gene family, member G	0.037
Kit	kit oncogene	0.037
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.037
Phc2	polyhomeotic-like 2 (Drosophila)	0.037
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.036
Cfl1	cofilin 1, non-muscle	0.035
Bcl2l1	BCL2-like 1	0.035	Mouse
Tgfb1	transforming growth factor, beta 1	0.035
Gtse1	G two S phase expressed protein 1	0.034
Myo1c	myosin IC	0.034
Cdx2	caudal type homeobox 2	0.034
Ccne1	cyclin E1	0.033
Rc3h1	RING CCCH (C3H) domains 1	0.033
Cnn2	calponin 2	0.033	Yeast
Fam64a	family with sequence similarity 64, member A	0.033
Foxf1a	forkhead box F1a	0.033
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.033
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.033
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.033
Shox2	short stature homeobox 2	0.032
Mfn2	mitofusin 2	0.032
Creb1	cAMP responsive element binding protein 1	0.032
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.031
Msx2	homeobox, msh-like 2	0.031
Sox9	SRY-box containing gene 9	0.031
Top2a	topoisomerase (DNA) II alpha	0.031
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.031
Bdnf	brain derived neurotrophic factor	0.030
Spry4	sprouty homolog 4 (Drosophila)	0.030
Ighmbp2	immunoglobulin mu binding protein 2	0.030
Rara	retinoic acid receptor, alpha	0.030
Sim1	single-minded homolog 1 (Drosophila)	0.030
Prdm1	PR domain containing 1, with ZNF domain	0.030
Otx1	orthodenticle homolog 1 (Drosophila)	0.030
Shh	sonic hedgehog	0.030
Stk11	serine/threonine kinase 11	0.030
Ctgf	connective tissue growth factor	0.029
Tor1aip2	torsin A interacting protein 2	0.029
Vcl	vinculin	0.029
Lmnb2	lamin B2	0.029	Fly
Ccnf	cyclin F	0.029
Hes1	hairy and enhancer of split 1 (Drosophila)	0.029
Acvrl1	activin A receptor, type II-like 1	0.028	Mouse
H2afx	H2A histone family, member X	0.028
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.028
Prkg1	protein kinase, cGMP-dependent, type I	0.028
Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.028
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.028
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.028
Hbegf	heparin-binding EGF-like growth factor	0.027
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.027	Yeast
Kiss1	KiSS-1 metastasis-suppressor	0.027
Asxl1	additional sex combs like 1 (Drosophila)	0.027
Gnrh1	gonadotropin releasing hormone 1	0.027
Tenc1	tensin like C1 domain-containing phosphatase	0.027
Smtn	smoothelin	0.027
Runx2	runt related transcription factor 2	0.027
Eng	endoglin	0.027
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.027
Iqgap3	IQ motif containing GTPase activating protein 3	0.027
Kdm1a	lysine (K)-specific demethylase 1A	0.027
Tcrb	T-cell receptor beta chain	0.026
Ctnnb1	catenin (cadherin associated protein), beta 1	0.026
Nipa2	non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)	0.026
Myc	myelocytomatosis oncogene	0.026
Rora	RAR-related orphan receptor alpha	0.026
Glipr2	GLI pathogenesis-related 2	0.026
Ckap4	cytoskeleton-associated protein 4	0.026
Sfn	stratifin	0.026
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.026
Tcrd	T-cell receptor delta chain	0.026
Rest	RE1-silencing transcription factor	0.026
Zeb1	zinc finger E-box binding homeobox 1	0.025
Mib1	mindbomb homolog 1 (Drosophila)	0.025
Zic3	zinc finger protein of the cerebellum 3	0.025
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.025
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.025
Crb2	crumbs homolog 2 (Drosophila)	0.025
Fgf2	fibroblast growth factor 2	0.025
Twist1	twist homolog 1 (Drosophila)	0.025	Human
Btrc	beta-transducin repeat containing protein	0.025
Clic1	chloride intracellular channel 1	0.025
Adm	adrenomedullin	0.025
Arpc4	actin related protein 2/3 complex, subunit 4	0.025
Pikfyve	phosphoinositide kinase, FYVE finger containing	0.025
Mkl2	MKL/myocardin-like 2	0.024
Tmsb4x	thymosin, beta 4, X chromosome	0.024
Noto	notochord homolog (Xenopus laevis)	0.024
Hip1	huntingtin interacting protein 1	0.024
Diablo	diablo homolog (Drosophila)	0.024
Ece1	endothelin converting enzyme 1	0.024
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.024
Kif5c	kinesin family member 5C	0.024
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.024
Actg2	actin, gamma 2, smooth muscle, enteric	0.024
Sox17	SRY-box containing gene 17	0.024
Rasip1	Ras interacting protein 1	0.024
Dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.024
Ifng	interferon gamma	0.024
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.024
Uck2	uridine-cytidine kinase 2	0.024
Cyld	cylindromatosis (turban tumor syndrome)	0.023
Hoxd8	homeobox D8	0.023
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.023
Igbp1	immunoglobulin (CD79A) binding protein 1	0.023
Axin1	axin 1	0.023
Becn1	beclin 1, autophagy related	0.023
Iqgap1	IQ motif containing GTPase activating protein 1	0.023
Inhba	inhibin beta-A	0.023
Casp3	caspase 3	0.023
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.023
Igfbp7	insulin-like growth factor binding protein 7	0.023
Foxc1	forkhead box C1	0.023
Prc1	protein regulator of cytokinesis 1	0.022
Hoxd13	homeobox D13	0.022
Ube3a	ubiquitin protein ligase E3A	0.022
Nsd1	nuclear receptor-binding SET-domain protein 1	0.022
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.022
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.022
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.022
Aurka	aurora kinase A	0.022
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.022
Ate1	arginyltransferase 1	0.022
Lbr	lamin B receptor	0.022
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.022
Cdk6	cyclin-dependent kinase 6	0.022	Human
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.021
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.021
Gprc6a	G protein-coupled receptor, family C, group 6, member A	0.021
Actn4	actinin alpha 4	0.021
Ifngr1	interferon gamma receptor 1	0.021
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.021
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.021
Map2k3	mitogen-activated protein kinase kinase 3	0.021
Setdb1	SET domain, bifurcated 1	0.021
Yap1	yes-associated protein 1	0.021
Wt1	Wilms tumor 1 homolog	0.021
Icam2	intercellular adhesion molecule 2	0.021
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.021
Txn1	thioredoxin 1	0.020
Ikzf1	IKAROS family zinc finger 1	0.020
Inhbb	inhibin beta-B	0.020
Hand2	heart and neural crest derivatives expressed transcript 2	0.020
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.020
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.020
Lrp6	low density lipoprotein receptor-related protein 6	0.020
Klf3	Kruppel-like factor 3 (basic)	0.020
Prrx2	paired related homeobox 2	0.020
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.020
Haus4	HAUS augmin-like complex, subunit 4	0.020
E130303B06Rik	RIKEN cDNA E130303B06 gene	0.020
Smad5	MAD homolog 5 (Drosophila)	0.020
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.020
Fgf7	fibroblast growth factor 7	0.020
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.020
Mfge8	milk fat globule-EGF factor 8 protein	0.020
Flna	filamin, alpha	0.020
1110008F13Rik	RIKEN cDNA 1110008F13 gene	0.020
Rsbn1	rosbin, round spermatid basic protein 1	0.020
Mmp16	matrix metallopeptidase 16	0.020
Nup188	nucleoporin 188	0.020
Ptch1	patched homolog 1	0.019
Errfi1	ERBB receptor feedback inhibitor 1	0.019
Tubb5	tubulin, beta 5	0.019
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.019	Yeast
Acta2	actin, alpha 2, smooth muscle, aorta	0.019
Fbxl5	F-box and leucine-rich repeat protein 5	0.019
Ppard	peroxisome proliferator activator receptor delta	0.019
Dmxl1	Dmx-like 1	0.019
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.019
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.019
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.019
Sertad1	SERTA domain containing 1	0.019
Wdr1	WD repeat domain 1	0.018
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.018
Kif20a	kinesin family member 20A	0.018
Pdlim7	PDZ and LIM domain 7	0.018
Mapk11	mitogen-activated protein kinase 11	0.018
Irf8	interferon regulatory factor 8	0.018
Olig1	oligodendrocyte transcription factor 1	0.018
Sox2	SRY-box containing gene 2	0.018
Ccnb1	cyclin B1	0.018
Cyr61	cysteine rich protein 61	0.018
Kif3a	kinesin family member 3A	0.018
Kdm2b	lysine (K)-specific demethylase 2B	0.018
Bbc3	BCL2 binding component 3	0.018
Lrpprc	leucine-rich PPR-motif containing	0.018
Myf5	myogenic factor 5	0.018
Ehmt1	euchromatic histone methyltransferase 1	0.018
Bptf	bromodomain PHD finger transcription factor	0.018
Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)	0.018
Nod2	nucleotide-binding oligomerization domain containing 2	0.018
Pias1	protein inhibitor of activated STAT 1	0.017
Ptgfr	prostaglandin F receptor	0.017
Opa1	optic atrophy 1 homolog (human)	0.017	Human
Ncoa2	nuclear receptor coactivator 2	0.017
Ncoa3	nuclear receptor coactivator 3	0.017
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.017
Cxcr4	chemokine (C-X-C motif) receptor 4	0.017
Kctd10	potassium channel tetramerisation domain containing 10	0.017
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.017
Fam129b	family with sequence similarity 129, member B	0.017
Rab5b	RAB5B, member RAS oncogene family	0.017
Midn	midnolin	0.017
Lonp1	lon peptidase 1, mitochondrial	0.017
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.017	Mouse
Sos1	son of sevenless homolog 1 (Drosophila)	0.017	Yeast
Wrn	Werner syndrome homolog (human)	0.017
Pola1	polymerase (DNA directed), alpha 1	0.017
Sema6c	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.017
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.017
Notch1	Notch gene homolog 1 (Drosophila)	0.017
Tlx3	T-cell leukemia, homeobox 3	0.017
Shprh	SNF2 histone linker PHD RING helicase	0.017
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.017
Sgpp1	sphingosine-1-phosphate phosphatase 1	0.017
Zyx	zyxin	0.016
Csrp1	cysteine and glycine-rich protein 1	0.016
Lhx9	LIM homeobox protein 9	0.016
Atp6v1e2	ATPase, H+ transporting, lysosomal V1 subunit E2	0.016
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.016
Otx2	orthodenticle homolog 2 (Drosophila)	0.016
Cnn1	calponin 1	0.016	Yeast
Tbx2	T-box 2	0.016
Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.016
Npr2	natriuretic peptide receptor 2	0.016
Chd2	chromodomain helicase DNA binding protein 2	0.016
Flcn	folliculin	0.016
Kpna1	karyopherin (importin) alpha 1	0.016
Prrx1	paired related homeobox 1	0.016
Plaur	plasminogen activator, urokinase receptor	0.016
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.016
Itgbl1	integrin, beta-like 1	0.016
Dsg4	desmoglein 4	0.016
En2	engrailed 2	0.016
Tnmd	tenomodulin	0.016
Csf1	colony stimulating factor 1 (macrophage)	0.016
Cdca3	cell division cycle associated 3	0.016
Mecp2	methyl CpG binding protein 2	0.016
Srebf2	sterol regulatory element binding factor 2	0.016
Etf1	eukaryotic translation termination factor 1	0.016
Inha	inhibin alpha	0.016
Chd7	chromodomain helicase DNA binding protein 7	0.016
Trpm7	transient receptor potential cation channel, subfamily M, member 7	0.016
Hoxc9	homeobox C9	0.015
Eomes	eomesodermin homolog (Xenopus laevis)	0.015	Mouse
Ifngr2	interferon gamma receptor 2	0.015
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.015
Parva	parvin, alpha	0.015
Mllt10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	0.015
Foxp1	forkhead box P1	0.015
Wwc2	WW, C2 and coiled-coil domain containing 2	0.015
T	brachyury	0.015	Mouse
Gata4	GATA binding protein 4	0.015
Usp45	ubiquitin specific petidase 45	0.015
Fgfrl1	fibroblast growth factor receptor-like 1	0.015
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.015
Chrd	chordin	0.015
P4hb	prolyl 4-hydroxylase, beta polypeptide	0.015
Gpr98	G protein-coupled receptor 98	0.015
Zbtb33	zinc finger and BTB domain containing 33	0.015
Olig2	oligodendrocyte transcription factor 2	0.015
Sox18	SRY-box containing gene 18	0.015
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.015
Grik3	glutamate receptor, ionotropic, kainate 3	0.015
Lcp1	lymphocyte cytosolic protein 1	0.015
Tpm1	tropomyosin 1, alpha	0.015
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.015
Zfyve16	zinc finger, FYVE domain containing 16	0.015
Msc	musculin	0.015
Lrrc58	leucine rich repeat containing 58	0.015
Fbn1	fibrillin 1	0.015
Nampt	nicotinamide phosphoribosyltransferase	0.015
Etv6	ets variant gene 6 (TEL oncogene)	0.014
Cul4a	cullin 4A	0.014
Ehd1	EH-domain containing 1	0.014
Kdr	kinase insert domain protein receptor	0.014
Cd274	CD274 antigen	0.014
Bmf	BCL2 modifying factor	0.014
Mtmr6	myotubularin related protein 6	0.014
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.014
Angpt1	angiopoietin 1	0.014
Dna2	DNA replication helicase 2 homolog (yeast)	0.014
Ldb3	LIM domain binding 3	0.014
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.014
Lep	leptin	0.014
Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	0.014
Pknox1	Pbx/knotted 1 homeobox	0.014
Chaf1a	chromatin assembly factor 1, subunit A (p150)	0.014
Elf4	E74-like factor 4 (ets domain transcription factor)	0.014
Men1	multiple endocrine neoplasia 1	0.014
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.014
Ccni	cyclin I	0.014
Klf4	Kruppel-like factor 4 (gut)	0.014
Pcmtd2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	0.014
Gata5	GATA binding protein 5	0.014
Tiam2	T-cell lymphoma invasion and metastasis 2	0.014
Gdnf	glial cell line derived neurotrophic factor	0.014
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.014
Tubb6	tubulin, beta 6	0.014
Hmbox1	homeobox containing 1	0.014
Hif1a	hypoxia inducible factor 1, alpha subunit	0.014
Fmod	fibromodulin	0.014
Edn1	endothelin 1	0.013
Sod2	superoxide dismutase 2, mitochondrial	0.013
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.013
Hesx1	homeobox gene expressed in ES cells	0.013
Cd151	CD151 antigen	0.013
Snap25	synaptosomal-associated protein 25	0.013
Ffar3	free fatty acid receptor 3	0.013
Mapk9	mitogen-activated protein kinase 9	0.013
Srpx	sushi-repeat-containing protein	0.013
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.013
Il6st	interleukin 6 signal transducer	0.013
Trip6	thyroid hormone receptor interactor 6	0.013
Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.013
Tuba1a	tubulin, alpha 1A	0.013
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.013
Zfhx4	zinc finger homeodomain 4	0.013
Myh9	myosin, heavy polypeptide 9, non-muscle	0.013
Smad1	MAD homolog 1 (Drosophila)	0.013
Prlr	prolactin receptor	0.013
Pcgf5	polycomb group ring finger 5	0.013
E2f3	E2F transcription factor 3	0.013
Mgp	matrix Gla protein	0.013
Dhh	desert hedgehog	0.013
Surf4	surfeit gene 4	0.013
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.013
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.013
Kif4	kinesin family member 4	0.013
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.013
Bmp2	bone morphogenetic protein 2	0.013
Dmtf1	cyclin D binding myb-like transcription factor 1	0.013
Ppa1	pyrophosphatase (inorganic) 1	0.013
Wnt9a	wingless-type MMTV integration site 9A	0.013
Tmed2	transmembrane emp24 domain trafficking protein 2	0.013
Gdf3	growth differentiation factor 3	0.013
Lap3	leucine aminopeptidase 3	0.013
Meox2	mesenchyme homeobox 2	0.013
Blm	Bloom syndrome, RecQ helicase-like	0.013
Dpy19l4	dpy-19-like 4 (C. elegans)	0.013
Itga6	integrin alpha 6	0.013
Foxm1	forkhead box M1	0.013	Human
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.013
Tmx3	thioredoxin-related transmembrane protein 3	0.013
Pax3	paired box gene 3	0.013
Dcaf7	DDB1 and CUL4 associated factor 7	0.013
Obfc1	oligonucleotide/oligosaccharide-binding fold containing 1	0.013
Hltf	helicase-like transcription factor	0.013
Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	0.013
Got1	glutamate oxaloacetate transaminase 1, soluble	0.013
Mstn	myostatin	0.013
Kif11	kinesin family member 11	0.013
Pgr	progesterone receptor	0.012
Aurkb	aurora kinase B	0.012
Mxd3	Max dimerization protein 3	0.012	Mouse
Klhl24	kelch-like 24 (Drosophila)	0.012
Esam	endothelial cell-specific adhesion molecule	0.012
Pbrm1	polybromo 1	0.012
Snn	stannin	0.012
Rps6ka5	ribosomal protein S6 kinase, polypeptide 5	0.012
Stk4	serine/threonine kinase 4	0.012
Anxa2	annexin A2	0.012
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.012
Dpep1	dipeptidase 1 (renal)	0.012
Runx3	runt related transcription factor 3	0.012
Wnt3	wingless-related MMTV integration site 3	0.012
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.012
Mvp	major vault protein	0.012
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.012
Robo1	roundabout homolog 1 (Drosophila)	0.012
Ccdc123	coiled-coil domain containing 123	0.012
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.012
Id2	inhibitor of DNA binding 2	0.012
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.012
Rbms2	RNA binding motif, single stranded interacting protein 2	0.012
Mfn1	mitofusin 1	0.012
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.012
Tgif2	TGFB-induced factor homeobox 2	0.012
Fgf15	fibroblast growth factor 15	0.012
Nphs2	nephrosis 2 homolog, podocin (human)	0.012
Nes	nestin	0.012
Magea5	melanoma antigen, family A, 5	0.012	Human
Gab2	growth factor receptor bound protein 2-associated protein 2	0.012
Hspb1	heat shock protein 1	0.012
Cldn5	claudin 5	0.012
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.012
Robo4	roundabout homolog 4 (Drosophila)	0.012
Stxbp3a	syntaxin binding protein 3A	0.012
Mapk8	mitogen-activated protein kinase 8	0.012
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.012
Tmem38b	transmembrane protein 38B	0.012
Ids	iduronate 2-sulfatase	0.012
Klf2	Kruppel-like factor 2 (lung)	0.012
Hsf2	heat shock factor 2	0.012
Cct6b	chaperonin containing Tcp1, subunit 6b (zeta)	0.012
Pkm2	pyruvate kinase, muscle	0.012
Col12a1	collagen, type XII, alpha 1	0.012
Pofut1	protein O-fucosyltransferase 1	0.012
Gabarap	gamma-aminobutyric acid receptor associated protein	0.011
Plekha5	pleckstrin homology domain containing, family A member 5	0.011
Actn3	actinin alpha 3	0.011
Cul4b	cullin 4B	0.011
B2m	beta-2 microglobulin	0.011
Tes	testis derived transcript	0.011
Taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.011
Elf1	E74-like factor 1	0.011
Cd97	CD97 antigen	0.011
Ubr1	ubiquitin protein ligase E3 component n-recognin 1	0.011
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.011
Adam33	a disintegrin and metallopeptidase domain 33	0.011
H2-D1	histocompatibility 2, D region locus 1	0.011
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.011
Iffo2	intermediate filament family orphan 2	0.011
Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5	0.011
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.011
Cdt1	chromatin licensing and DNA replication factor 1	0.011
Cdca4	cell division cycle associated 4	0.011
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.011
Fzd4	frizzled homolog 4 (Drosophila)	0.011
Incenp	inner centromere protein	0.011
Myh10	myosin, heavy polypeptide 10, non-muscle	0.011
Timm8a1	translocase of inner mitochondrial membrane 8 homolog a1 (yeast)	0.011
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.011
Rhoj	ras homolog gene family, member J	0.011
Ank	progressive ankylosis	0.011
Tex11	testis expressed gene 11	0.011
Nxf2	nuclear RNA export factor 2	0.011
Vamp3	vesicle-associated membrane protein 3	0.011
Polg	polymerase (DNA directed), gamma	0.011
Tmsb10	thymosin, beta 10	0.011
Gli2	GLI-Kruppel family member GLI2	0.011
Mc4r	melanocortin 4 receptor	0.011
Myf6	myogenic factor 6	0.011
Scyl1	SCY1-like 1 (S. cerevisiae)	0.011
Col13a1	collagen, type XIII, alpha 1	0.011
Nhedc1	Na+/H+ exchanger domain containing 1	0.011
Fam108a	family with sequence similarity 108, member A	0.011
Prkce	protein kinase C, epsilon	0.011
Xiap	X-linked inhibitor of apoptosis	0.011
Taf1d	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, D	0.011
D14Abb1e	DNA segment, Chr 14, Abbott 1 expressed	0.011
Kpna3	karyopherin (importin) alpha 3	0.011
Mga	MAX gene associated	0.011	Mouse
Asb12	ankyrin repeat and SOCS box-containing 12	0.011
Rnf8	ring finger protein 8	0.011
Zfand3	zinc finger, AN1-type domain 3	0.011
Pxn	paxillin	0.011
Aicda	activation-induced cytidine deaminase	0.011
Slc33a1	solute carrier family 33 (acetyl-CoA transporter), member 1	0.011
Lamc2	laminin, gamma 2	0.011
Pola2	polymerase (DNA directed), alpha 2	0.011
Foxp2	forkhead box P2	0.011
Chuk	conserved helix-loop-helix ubiquitous kinase	0.011
Atoh8	atonal homolog 8 (Drosophila)	0.011
4732456N10Rik	RIKEN cDNA 4732456N10 gene	0.011
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.011
Bcl3	B-cell leukemia/lymphoma 3	0.011
Cep110	centrosomal protein 110	0.011
Prkd3	protein kinase D3	0.011
Hand1	heart and neural crest derivatives expressed transcript 1	0.011
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.011
Acvr2a	activin receptor IIA	0.011
Gm16517	predicted gene, Gm16517	0.011
Rhbdf1	rhomboid family 1 (Drosophila)	0.011
Lmod1	leiomodin 1 (smooth muscle)	0.011
Kl	klotho	0.011
Mov10l1	Moloney leukemia virus 10-like 1	0.010
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.010
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.010
Spnb1	spectrin beta 1	0.010
Cdca7l	cell division cycle associated 7 like	0.010
Prkcdbp	protein kinase C, delta binding protein	0.010
Dcbld2	discoidin, CUB and LCCL domain containing 2	0.010
Defb10	defensin beta 10	0.010
Map2k2	mitogen-activated protein kinase kinase 2	0.010
Nhej1	nonhomologous end-joining factor 1	0.010
Sh2b3	SH2B adaptor protein 3	0.010
Tpm2	tropomyosin 2, beta	0.010
Hr	hairless	0.010
Hic1	hypermethylated in cancer 1	0.010
Klhl2	kelch-like 2, Mayven (Drosophila)	0.010
Marcksl1	MARCKS-like 1	0.010
Fktn	fukutin	0.010
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.010
4933403F05Rik	RIKEN cDNA 4933403F05 gene	0.010
Cdc27	cell division cycle 27 homolog (S. cerevisiae)	0.010
Hoxc8	homeobox C8	0.010
Gtpbp4	GTP binding protein 4	0.010
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.010
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.010
Fancg	Fanconi anemia, complementation group G	0.010
Il2rg	interleukin 2 receptor, gamma chain	0.010
1700029P11Rik	RIKEN cDNA 1700029P11 gene	0.010
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.010
Itgal	integrin alpha L	0.010
Sgpl1	sphingosine phosphate lyase 1	0.010
Zp3	zona pellucida glycoprotein 3	0.010
Xpa	xeroderma pigmentosum, complementation group A	0.010
Sod3	superoxide dismutase 3, extracellular	0.010
Pou4f3	POU domain, class 4, transcription factor 3	0.010
Hipk3	homeodomain interacting protein kinase 3	0.010
Atrip	ATR interacting protein	0.010
Thbd	thrombomodulin	0.010
Dppa4	developmental pluripotency associated 4	0.010
Eif4a1	eukaryotic translation initiation factor 4A1	0.010
Rprd2	regulation of nuclear pre-mRNA domain containing 2	0.010
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.010