IMP
Process View
intrinsic apoptotic signaling pathway by p53 class mediator
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
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Click on a gene's description to view its network relationships with genes known to be involved in "intrinsic apoptotic signaling pathway by p53 class mediator"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 1.000 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 1.000 | ||
| Rb1 | retinoblastoma 1 | 0.997 | ||
| Apc | adenomatosis polyposis coli | 0.997 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.984 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.982 | Mouse | |
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.967 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.953 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.937 | Mouse | |
| Brca1 | breast cancer 1 | 0.925 | ||
| Skil | SKI-like | 0.923 | ||
| Pten | phosphatase and tensin homolog | 0.890 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.857 | ||
| Bax | BCL2-associated X protein | 0.856 | ||
| Braf | Braf transforming gene | 0.845 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.804 | ||
| Mcl1 | myeloid cell leukemia sequence 1 | 0.758 | Mouse | |
| E2f1 | E2F transcription factor 1 | 0.732 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.696 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.687 | ||
| Lepr | leptin receptor | 0.672 | ||
| Ren1 | renin 1 structural | 0.653 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.652 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.641 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.633 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.613 | ||
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.550 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.530 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.513 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.512 | ||
| Thbs1 | thrombospondin 1 | 0.474 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.470 | ||
| Wt1 | Wilms tumor 1 homolog | 0.398 | ||
| Ret | ret proto-oncogene | 0.386 | ||
| Trp63 | transformation related protein 63 | 0.385 | ||
| Cd151 | CD151 antigen | 0.360 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.353 | ||
| Ccnd1 | cyclin D1 | 0.353 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.352 | Mouse | |
| Casp1 | caspase 1 | 0.352 | ||
| Ptch1 | patched homolog 1 | 0.339 | ||
| Gbp5 | guanylate binding protein 5 | 0.330 | ||
| Igh | immunoglobulin heavy chain complex | 0.326 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.316 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.296 | ||
| Rxra | retinoid X receptor alpha | 0.285 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.283 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.280 | ||
| Mndal | myeloid nuclear differentiation antigen like | 0.240 | ||
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.225 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.223 | ||
| Stk11 | serine/threonine kinase 11 | 0.222 | Human | |
| Tnf | tumor necrosis factor | 0.221 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.217 | ||
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.198 | ||
| Daxx | Fas death domain-associated protein | 0.197 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.195 | ||
| Tfdp2 | transcription factor Dp 2 | 0.187 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.178 | ||
| Edaradd | EDAR (ectodysplasin-A receptor)-associated death domain | 0.176 | ||
| Nf1 | neurofibromatosis 1 | 0.170 | ||
| Kit | kit oncogene | 0.168 | ||
| Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.164 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.157 | ||
| Stk4 | serine/threonine kinase 4 | 0.145 | ||
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.144 | ||
| Lyz2 | lysozyme 2 | 0.140 | ||
| Cux1 | cut-like homeobox 1 | 0.139 | ||
| Ik | IK cytokine | 0.139 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.131 | ||
| Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.131 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.127 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.122 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.122 | ||
| Eda | ectodysplasin-A | 0.119 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.114 | Mouse | |
| Nf2 | neurofibromatosis 2 | 0.113 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.112 | ||
| Kdm2b | lysine (K)-specific demethylase 2B | 0.104 | ||
| Aim2 | absent in melanoma 2 | 0.103 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.102 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.102 | ||
| Foxo3 | forkhead box O3 | 0.101 | ||
| Brca2 | breast cancer 2 | 0.099 | ||
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.092 | ||
| Vegfa | vascular endothelial growth factor A | 0.091 | ||
| Nbn | nibrin | 0.091 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.089 | ||
| Bcl2l1 | BCL2-like 1 | 0.089 | Mouse | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.089 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.086 | ||
| H2-Aa | histocompatibility 2, class II antigen A, alpha | 0.085 | ||
| Dlx5 | distal-less homeobox 5 | 0.083 | ||
| Ly6a | lymphocyte antigen 6 complex, locus A | 0.080 | ||
| H2-Eb1 | histocompatibility 2, class II antigen E beta | 0.078 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.077 | ||
| Runx1 | runt related transcription factor 1 | 0.077 | ||
| Trp73 | transformation related protein 73 | 0.077 | ||
| Cdkn2d | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 0.076 | ||
| Icam1 | intercellular adhesion molecule 1 | 0.073 | ||
| Ahr | aryl-hydrocarbon receptor | 0.073 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.072 | ||
| Axin1 | axin 1 | 0.067 | ||
| Fbxo11 | F-box protein 11 | 0.064 | ||
| Lox | lysyl oxidase | 0.064 | ||
| Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.063 | ||
| Hdac1 | histone deacetylase 1 | 0.059 | ||
| Agtrap | angiotensin II, type I receptor-associated protein | 0.057 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.057 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.057 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.057 | ||
| Osmr | oncostatin M receptor | 0.056 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.055 | ||
| Ppard | peroxisome proliferator activator receptor delta | 0.055 | ||
| Ppp2ca | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 0.054 | ||
| Rara | retinoic acid receptor, alpha | 0.054 | ||
| Ttn | titin | 0.051 | ||
| Cd40 | CD40 antigen | 0.051 | ||
| AI607873 | expressed sequence AI607873 | 0.049 | ||
| Becn1 | beclin 1, autophagy related | 0.049 | ||
| Ifi203 | interferon activated gene 203 | 0.049 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.047 | ||
| Terf1 | telomeric repeat binding factor 1 | 0.046 | ||
| Nkx3-1 | NK-3 transcription factor, locus 1 (Drosophila) | 0.046 | ||
| Hist1h1b | histone cluster 1, H1b | 0.045 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.045 | ||
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.045 | ||
| Ldlr | low density lipoprotein receptor | 0.044 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.043 | ||
| Mnda | myeloid cell nuclear differentiation antigen | 0.043 | Human | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.043 | ||
| Nod2 | nucleotide-binding oligomerization domain containing 2 | 0.043 | ||
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.043 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.042 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.041 | ||
| Tsc1 | tuberous sclerosis 1 | 0.041 | ||
| Bdkrb2 | bradykinin receptor, beta 2 | 0.041 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.041 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.039 | ||
| Hbb-b1 | hemoglobin, beta adult major chain | 0.039 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.039 | ||
| Pax3 | paired box gene 3 | 0.038 | ||
| Myc | myelocytomatosis oncogene | 0.036 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.036 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.036 | ||
| Adsl | adenylosuccinate lyase | 0.035 | ||
| Fbn1 | fibrillin 1 | 0.035 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.035 | ||
| Ar | androgen receptor | 0.034 | ||
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.033 | ||
| Nacc1 | nucleus accumbens associated 1, BEN and BTB (POZ) domain containing | 0.033 | ||
| Cebpd | CCAAT/enhancer binding protein (C/EBP), delta | 0.033 | ||
| Tsc2 | tuberous sclerosis 2 | 0.032 | ||
| Smn1 | survival motor neuron 1 | 0.031 | ||
| Lats1 | large tumor suppressor | 0.031 | Fly | |
| Rybp | RING1 and YY1 binding protein | 0.031 | ||
| Rassf1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.030 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.030 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.029 | ||
| Mat2a | methionine adenosyltransferase II, alpha | 0.029 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.029 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.028 | ||
| Sav1 | salvador homolog 1 (Drosophila) | 0.028 | ||
| Vav2 | vav 2 oncogene | 0.028 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.027 | ||
| Atp7b | ATPase, Cu++ transporting, beta polypeptide | 0.027 | ||
| Gadd45a | growth arrest and DNA-damage-inducible 45 alpha | 0.027 | ||
| Yap1 | yes-associated protein 1 | 0.027 | ||
| Cav1 | caveolin 1, caveolae protein | 0.026 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.026 | ||
| Irf9 | interferon regulatory factor 9 | 0.026 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.026 | ||
| BC006779 | cDNA sequence BC006779 | 0.026 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.026 | ||
| Pcdh12 | protocadherin 12 | 0.026 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.025 | ||
| Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.025 | ||
| Zcchc10 | zinc finger, CCHC domain containing 10 | 0.025 | ||
| Wwox | WW domain-containing oxidoreductase | 0.025 | ||
| Rab5a | RAB5A, member RAS oncogene family | 0.025 | ||
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.025 | ||
| Hipk1 | homeodomain interacting protein kinase 1 | 0.025 | ||
| Slc39a4 | solute carrier family 39 (zinc transporter), member 4 | 0.025 | ||
| Anxa1 | annexin A1 | 0.024 | ||
| Ptx3 | pentraxin related gene | 0.024 | ||
| Prkci | protein kinase C, iota | 0.024 | ||
| Csnk1a1 | casein kinase 1, alpha 1 | 0.024 | ||
| Spdef | SAM pointed domain containing ets transcription factor | 0.024 | ||
| Sox9 | SRY-box containing gene 9 | 0.024 | ||
| Ddx5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 0.024 | Human | |
| Hdac2 | histone deacetylase 2 | 0.024 | ||
| Rbm22 | RNA binding motif protein 22 | 0.024 | ||
| Prmt5 | protein arginine N-methyltransferase 5 | 0.023 | ||
| Vdr | vitamin D receptor | 0.023 | ||
| Ets1 | E26 avian leukemia oncogene 1, 5' domain | 0.023 | ||
| Sos2 | son of sevenless homolog 2 (Drosophila) | 0.023 | ||
| Paip2 | polyadenylate-binding protein-interacting protein 2 | 0.023 | ||
| Bmi1 | Bmi1 polycomb ring finger oncogene | 0.023 | ||
| Aff1 | AF4/FMR2 family, member 1 | 0.023 | ||
| Prrx1 | paired related homeobox 1 | 0.022 | ||
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.022 | ||
| Hnrnph1 | heterogeneous nuclear ribonucleoprotein H1 | 0.022 | ||
| Hmgb1 | high mobility group box 1 | 0.022 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.022 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.022 | ||
| Fbrs | fibrosin | 0.021 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.021 | ||
| Matr3 | matrin 3 | 0.021 | ||
| H3f3a | H3 histone, family 3A | 0.021 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.021 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.021 | ||
| Meox2 | mesenchyme homeobox 2 | 0.020 | ||
| Ncoa2 | nuclear receptor coactivator 2 | 0.020 | ||
| Tlr4 | toll-like receptor 4 | 0.020 | ||
| Tiam1 | T-cell lymphoma invasion and metastasis 1 | 0.020 | ||
| Ms4a4d | membrane-spanning 4-domains, subfamily A, member 4D | 0.020 | ||
| Ptgs1 | prostaglandin-endoperoxide synthase 1 | 0.020 | ||
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | 0.020 | ||
| Ctla2a | cytotoxic T lymphocyte-associated protein 2 alpha | 0.020 | ||
| Sox2 | SRY-box containing gene 2 | 0.020 | ||
| Hnrnph2 | heterogeneous nuclear ribonucleoprotein H2 | 0.020 | ||
| Itgb3 | integrin beta 3 | 0.020 | ||
| Mnd1 | meiotic nuclear divisions 1 homolog (S. cerevisiae) | 0.019 | ||
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.019 | ||
| Mlh1 | mutL homolog 1 (E. coli) | 0.019 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.019 | ||
| Kiss1r | KISS1 receptor | 0.019 | ||
| Stra6 | stimulated by retinoic acid gene 6 | 0.019 | ||
| Ep300 | E1A binding protein p300 | 0.019 | Human | |
| Nt5e | 5' nucleotidase, ecto | 0.019 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.019 | ||
| Cdh5 | cadherin 5 | 0.019 | ||
| Spry4 | sprouty homolog 4 (Drosophila) | 0.019 | ||
| Nanog | Nanog homeobox | 0.019 | ||
| Tbx21 | T-box 21 | 0.019 | ||
| L3mbtl2 | l(3)mbt-like 2 (Drosophila) | 0.019 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.018 | ||
| Myod1 | myogenic differentiation 1 | 0.018 | ||
| Casp3 | caspase 3 | 0.018 | ||
| Zfand5 | zinc finger, AN1-type domain 5 | 0.018 | ||
| Rint1 | RAD50 interactor 1 | 0.018 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.018 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.018 | ||
| Brd1 | bromodomain containing 1 | 0.018 | ||
| Prdx1 | peroxiredoxin 1 | 0.018 | ||
| Ube2e1 | ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast) | 0.018 | ||
| Ly6e | lymphocyte antigen 6 complex, locus E | 0.018 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.017 | ||
| Krt36 | keratin 36 | 0.017 | ||
| Dlx2 | distal-less homeobox 2 | 0.017 | ||
| Apoe | apolipoprotein E | 0.017 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.017 | ||
| A4galt | alpha 1,4-galactosyltransferase | 0.017 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.017 | ||
| Adcy4 | adenylate cyclase 4 | 0.017 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A2 | 0.017 | ||
| Fxyd5 | FXYD domain-containing ion transport regulator 5 | 0.017 | ||
| Eif4g2 | eukaryotic translation initiation factor 4, gamma 2 | 0.017 | ||
| Mvp | major vault protein | 0.017 | ||
| Tpx2 | TPX2, microtubule-associated protein homolog (Xenopus laevis) | 0.017 | ||
| Eif4ebp2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.017 | ||
| Mtor | mechanistic target of rapamycin (serine/threonine kinase) | 0.017 | ||
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.016 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.016 | ||
| Hoxb6 | homeobox B6 | 0.016 | ||
| Itga5 | integrin alpha 5 (fibronectin receptor alpha) | 0.016 | ||
| Sfn | stratifin | 0.016 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.016 | ||
| H2-D1 | histocompatibility 2, D region locus 1 | 0.016 | ||
| Eln | elastin | 0.016 | ||
| Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.016 | ||
| Tert | telomerase reverse transcriptase | 0.016 | ||
| Mmp3 | matrix metallopeptidase 3 | 0.016 | ||
| Serpine1 | serine (or cysteine) peptidase inhibitor, clade E, member 1 | 0.016 | ||
| Mterfd1 | MTERF domain containing 1 | 0.016 | ||
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.016 | ||
| Mapk14 | mitogen-activated protein kinase 14 | 0.016 | ||
| Areg | amphiregulin | 0.016 | ||
| Tgif2 | TGFB-induced factor homeobox 2 | 0.016 | ||
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.016 | ||
| Fam134b | family with sequence similarity 134, member B | 0.016 | ||
| Ube2d2 | ubiquitin-conjugating enzyme E2D 2 | 0.016 | ||
| Tgm2 | transglutaminase 2, C polypeptide | 0.016 | ||
| Ifitm3 | interferon induced transmembrane protein 3 | 0.016 | ||
| Sox18 | SRY-box containing gene 18 | 0.016 | ||
| Mta1 | metastasis associated 1 | 0.015 | ||
| Ifi27l2a | interferon, alpha-inducible protein 27 like 2A | 0.015 | ||
| Mas1 | MAS1 oncogene | 0.015 | ||
| Vcan | versican | 0.015 | ||
| Hcfc1 | host cell factor C1 | 0.015 | ||
| Ftsj3 | FtsJ homolog 3 (E. coli) | 0.015 | ||
| Isg20 | interferon-stimulated protein | 0.015 | ||
| Kitl | kit ligand | 0.015 | ||
| Popdc3 | popeye domain containing 3 | 0.015 | ||
| Procr | protein C receptor, endothelial | 0.015 | ||
| Pias4 | protein inhibitor of activated STAT 4 | 0.015 | ||
| Rora | RAR-related orphan receptor alpha | 0.015 | ||
| Cdk6 | cyclin-dependent kinase 6 | 0.015 | ||
| Zbtb33 | zinc finger and BTB domain containing 33 | 0.015 | ||
| Ehd3 | EH-domain containing 3 | 0.015 | ||
| Ly6c2 | lymphocyte antigen 6 complex, locus C2 | 0.015 | ||
| Hist1h1c | histone cluster 1, H1c | 0.015 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.015 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.014 | ||
| Meox1 | mesenchyme homeobox 1 | 0.014 | ||
| Foxa2 | forkhead box A2 | 0.014 | ||
| Sfpi1 | SFFV proviral integration 1 | 0.014 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.014 | ||
| Dmpk | dystrophia myotonica-protein kinase | 0.014 | ||
| Ccnj | cyclin J | 0.014 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.014 | ||
| Ythdf2 | YTH domain family 2 | 0.014 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.014 | ||
| Lif | leukemia inhibitory factor | 0.014 | ||
| Nol6 | nucleolar protein family 6 (RNA-associated) | 0.014 | ||
| Slc40a1 | solute carrier family 40 (iron-regulated transporter), member 1 | 0.014 | ||
| Zbtb7a | zinc finger and BTB domain containing 7a | 0.014 | ||
| C3 | complement component 3 | 0.014 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.014 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.014 | ||
| Ccng1 | cyclin G1 | 0.014 | ||
| Slc10a6 | solute carrier family 10 (sodium/bile acid cotransporter family), member 6 | 0.014 | ||
| Polr3d | polymerase (RNA) III (DNA directed) polypeptide D | 0.014 | ||
| Gpr56 | G protein-coupled receptor 56 | 0.014 | ||
| Irf1 | interferon regulatory factor 1 | 0.014 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.014 | ||
| Rgs16 | regulator of G-protein signaling 16 | 0.014 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.014 | ||
| Pgr | progesterone receptor | 0.014 | ||
| Hgfac | hepatocyte growth factor activator | 0.014 | ||
| Zxdb | zinc finger, X-linked, duplicated B | 0.014 | ||
| Bcl2a1a | B-cell leukemia/lymphoma 2 related protein A1a | 0.014 | Mouse | |
| Ctla2b | cytotoxic T lymphocyte-associated protein 2 beta | 0.014 | ||
| Ehd4 | EH-domain containing 4 | 0.014 | ||
| Pinx1 | PIN2/TERF1 interacting, telomerase inhibitor 1 | 0.013 | ||
| Jak3 | Janus kinase 3 | 0.013 | ||
| Axin2 | axin2 | 0.013 | ||
| Anxa8 | annexin A8 | 0.013 | ||
| Cdx2 | caudal type homeobox 2 | 0.013 | ||
| Ager | advanced glycosylation end product-specific receptor | 0.013 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.013 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.013 | ||
| Tead2 | TEA domain family member 2 | 0.013 | ||
| Ate1 | arginyltransferase 1 | 0.013 | ||
| Mllt1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | 0.013 | ||
| Xirp1 | xin actin-binding repeat containing 1 | 0.013 | ||
| Ifi204 | interferon activated gene 204 | 0.013 | Human | |
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.013 | ||
| Rtp4 | receptor transporter protein 4 | 0.013 | ||
| Robo2 | roundabout homolog 2 (Drosophila) | 0.013 | ||
| Med16 | mediator complex subunit 16 | 0.013 | ||
| Txndc17 | thioredoxin domain containing 17 | 0.013 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.013 | ||
| Ptpru | protein tyrosine phosphatase, receptor type, U | 0.013 | ||
| Zfp36l2 | zinc finger protein 36, C3H type-like 2 | 0.013 | ||
| Kcnk4 | potassium channel, subfamily K, member 4 | 0.013 | ||
| Vapa | vesicle-associated membrane protein, associated protein A | 0.013 | ||
| Bglap | bone gamma carboxyglutamate protein | 0.013 | ||
| Abcc1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.013 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.013 | ||
| Maf | avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog | 0.013 | ||
| Tnfrsf19 | tumor necrosis factor receptor superfamily, member 19 | 0.013 | Mouse | |
| Gja1 | gap junction protein, alpha 1 | 0.012 | ||
| Plac8 | placenta-specific 8 | 0.012 | ||
| Pax2 | paired box gene 2 | 0.012 | ||
| Vps37d | vacuolar protein sorting 37D (yeast) | 0.012 | ||
| Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a | 0.012 | ||
| Mybph | myosin binding protein H | 0.012 | ||
| Gbp3 | guanylate binding protein 3 | 0.012 | ||
| Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.012 | ||
| Mylpf | myosin light chain, phosphorylatable, fast skeletal muscle | 0.012 | ||
| Tmem123 | transmembrane protein 123 | 0.012 | ||
| Fscn1 | fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) | 0.012 | ||
| Pcgf3 | polycomb group ring finger 3 | 0.012 | ||
| Tnfrsf11b | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | 0.012 | ||
| Med14 | mediator complex subunit 14 | 0.012 | ||
| Hoxa6 | homeobox A6 | 0.012 | ||
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.012 | ||
| Lamc2 | laminin, gamma 2 | 0.012 | ||
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.012 | ||
| Wsb1 | WD repeat and SOCS box-containing 1 | 0.012 | ||
| Ccl11 | chemokine (C-C motif) ligand 11 | 0.012 | ||
| Bmf | BCL2 modifying factor | 0.012 | ||
| Bard1 | BRCA1 associated RING domain 1 | 0.012 | ||
| Casc3 | cancer susceptibility candidate 3 | 0.012 | ||
| Otud7b | OTU domain containing 7B | 0.012 | ||
| Tubb4 | tubulin, beta 4 | 0.012 | ||
| Agr2 | anterior gradient 2 (Xenopus laevis) | 0.012 | ||
| Irf2bp2 | interferon regulatory factor 2 binding protein 2 | 0.012 | ||
| Dmkn | dermokine | 0.012 | ||
| Irs2 | insulin receptor substrate 2 | 0.012 | ||
| Slc2a1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.012 | ||
| Sox7 | SRY-box containing gene 7 | 0.012 | ||
| Nphs2 | nephrosis 2 homolog, podocin (human) | 0.012 | ||
| Nlrp6 | NLR family, pyrin domain containing 6 | 0.012 | ||
| Drd4 | dopamine receptor D4 | 0.012 | ||
| Obfc2b | oligonucleotide/oligosaccharide-binding fold containing 2B | 0.012 | ||
| Adamts4 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 | 0.012 | ||
| Dclre1a | DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae) | 0.012 | ||
| Dvl3 | dishevelled 3, dsh homolog (Drosophila) | 0.012 | ||
| Smndc1 | survival motor neuron domain containing 1 | 0.012 | ||
| S100a6 | S100 calcium binding protein A6 (calcyclin) | 0.012 | ||
| Psen1 | presenilin 1 | 0.011 | ||
| Ppp2r2a | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 0.011 | ||
| Kars | lysyl-tRNA synthetase | 0.011 | ||
| Cd44 | CD44 antigen | 0.011 | ||
| St3gal1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.011 | ||
| Prmt1 | protein arginine N-methyltransferase 1 | 0.011 | ||
| Kat2a | K(lysine) acetyltransferase 2A | 0.011 | ||
| Tnfsf9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.011 | ||
| Ube2d3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.011 | ||
| Prkcd | protein kinase C, delta | 0.011 | ||
| Plscr1 | phospholipid scramblase 1 | 0.011 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.011 | ||
| Wtap | Wilms' tumour 1-associating protein | 0.011 | ||
| Vezf1 | vascular endothelial zinc finger 1 | 0.011 | ||
| Etv6 | ets variant gene 6 (TEL oncogene) | 0.011 | ||
| Cyp11b1 | cytochrome P450, family 11, subfamily b, polypeptide 1 | 0.011 | ||
| Cxcl16 | chemokine (C-X-C motif) ligand 16 | 0.011 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.011 | ||
| Irs1 | insulin receptor substrate 1 | 0.011 | ||
| Myo10 | myosin X | 0.011 | ||
| Pxn | paxillin | 0.011 | ||
| Rab5b | RAB5B, member RAS oncogene family | 0.011 | ||
| Adrb1 | adrenergic receptor, beta 1 | 0.011 | ||
| Sgk1 | serum/glucocorticoid regulated kinase 1 | 0.011 | ||
| Dok1 | docking protein 1 | 0.011 | ||
| Bid | BH3 interacting domain death agonist | 0.011 | ||
| Pvr | poliovirus receptor | 0.011 | ||
| Mdfi | MyoD family inhibitor | 0.011 | ||
| Atad5 | ATPase family, AAA domain containing 5 | 0.011 | ||
| Prmt2 | protein arginine N-methyltransferase 2 | 0.011 | ||
| Npy2r | neuropeptide Y receptor Y2 | 0.011 | ||
| Tsc22d3 | TSC22 domain family, member 3 | 0.011 | ||
| Asxl1 | additional sex combs like 1 (Drosophila) | 0.011 | ||
| Tbx15 | T-box 15 | 0.011 | ||
| Ogg1 | 8-oxoguanine DNA-glycosylase 1 | 0.011 | ||
| Srgn | serglycin | 0.011 | ||
| Ap2a1 | adaptor protein complex AP-2, alpha 1 subunit | 0.011 | ||
| Crh | corticotropin releasing hormone | 0.011 | ||
| Rsph1 | radial spoke head 1 homolog (Chlamydomonas) | 0.011 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.011 | ||
| Pogz | pogo transposable element with ZNF domain | 0.011 | ||
| Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) | 0.011 | ||
| Mtmr3 | myotubularin related protein 3 | 0.011 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.011 | ||
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.011 | ||
| Rbm18 | RNA binding motif protein 18 | 0.011 | ||
| Sesn1 | sestrin 1 | 0.011 | ||
| Gbp2 | guanylate binding protein 2 | 0.011 | ||
| Mga | MAX gene associated | 0.010 | ||
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.010 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.010 | ||
| Htatip2 | HIV-1 tat interactive protein 2, homolog (human) | 0.010 | ||
| 2010106G01Rik | RIKEN cDNA 2010106G01 gene | 0.010 | ||
| Utp20 | UTP20, small subunit (SSU) processome component, homolog (yeast) | 0.010 | ||
| Fbxo38 | F-box protein 38 | 0.010 | ||
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.010 | ||
| Clip2 | CAP-GLY domain containing linker protein 2 | 0.010 | ||
| Rnft1 | ring finger protein, transmembrane 1 | 0.010 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.010 | ||
| Tcf3 | transcription factor 3 | 0.010 | ||
| Mt2 | metallothionein 2 | 0.010 | ||
| Klc2 | kinesin light chain 2 | 0.010 | ||
| Prmt3 | protein arginine N-methyltransferase 3 | 0.010 | ||
| Yy1 | YY1 transcription factor | 0.010 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.010 | ||
| Bach1 | BTB and CNC homology 1 | 0.010 | ||
| Mark4 | MAP/microtubule affinity-regulating kinase 4 | 0.010 | ||
| Sdc1 | syndecan 1 | 0.010 | ||
| Jag2 | jagged 2 | 0.010 |