IMP: Integrative Multi-species Prediction

Mus musculus

30 genes annotated in mouse

response to dsrna

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to dsrna"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to dsrna" (in gray)

Name	Description	Probability	Func Analog Organism
Myd88	myeloid differentiation primary response gene 88	0.959
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.957
Lyz2	lysozyme 2	0.902
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.883
Irf9	interferon regulatory factor 9	0.873	Mouse
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.870
Tnf	tumor necrosis factor	0.827	Zebrafish
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.804
Igh	immunoglobulin heavy chain complex	0.793
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.764
Traf6	TNF receptor-associated factor 6	0.737
Stat3	signal transducer and activator of transcription 3	0.649	Mouse
Irf7	interferon regulatory factor 7	0.611	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.483
Tlr4	toll-like receptor 4	0.469
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.464
Mcl1	myeloid cell leukemia sequence 1	0.442
Usp18	ubiquitin specific peptidase 18	0.426
Stat2	signal transducer and activator of transcription 2	0.423	Mouse
Gbp2	guanylate binding protein 2	0.399
Ikzf1	IKAROS family zinc finger 1	0.387
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.376
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.340
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.308
Casp1	caspase 1	0.286
Stat5a	signal transducer and activator of transcription 5A	0.276	Mouse
Rtp4	receptor transporter protein 4	0.262
Irgm1	immunity-related GTPase family M member 1	0.258
Ifnar1	interferon (alpha and beta) receptor 1	0.245
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.245
Irak4	interleukin-1 receptor-associated kinase 4	0.239
Irgm2	immunity-related GTPase family M member 2	0.238
Stat1	signal transducer and activator of transcription 1	0.232
Trim21	tripartite motif-containing 21	0.225
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.218
Isg15	ISG15 ubiquitin-like modifier	0.213
Il1r1	interleukin 1 receptor, type I	0.199
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.197
Parp14	poly (ADP-ribose) polymerase family, member 14	0.192
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.180
Stat5b	signal transducer and activator of transcription 5B	0.174	Mouse
Parp9	poly (ADP-ribose) polymerase family, member 9	0.146
BC006779	cDNA sequence BC006779	0.146
Trim25	tripartite motif-containing 25	0.139
Il4ra	interleukin 4 receptor, alpha	0.131
Sfpi1	SFFV proviral integration 1	0.120
Unc93b1	unc-93 homolog B1 (C. elegans)	0.118
Il1b	interleukin 1 beta	0.117	Zebrafish
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.114
Ticam1	toll-like receptor adaptor molecule 1	0.104
Inadl	InaD-like (Drosophila)	0.104
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.100	Mouse Worm
Il6st	interleukin 6 signal transducer	0.085
Nlrp3	NLR family, pyrin domain containing 3	0.083	Mouse
Ifi35	interferon-induced protein 35	0.083
Bcl3	B-cell leukemia/lymphoma 3	0.083	Mouse
Zbp1	Z-DNA binding protein 1	0.082
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.074	Human
Cd40	CD40 antigen	0.072
Pycard	PYD and CARD domain containing	0.071
Irak3	interleukin-1 receptor-associated kinase 3	0.070
Foxp3	forkhead box P3	0.069
Rsad2	radical S-adenosyl methionine domain containing 2	0.068
Trim30a	tripartite motif-containing 30A	0.063
Cd44	CD44 antigen	0.061
Parp10	poly (ADP-ribose) polymerase family, member 10	0.060
Sfn	stratifin	0.060
Il22	interleukin 22	0.060
Il10	interleukin 10	0.058
Fas	Fas (TNF receptor superfamily member 6)	0.058
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.057
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.053
Igtp	interferon gamma induced GTPase	0.052
Ifi44	interferon-induced protein 44	0.052
Oas1a	2'-5' oligoadenylate synthetase 1A	0.050
Ifih1	interferon induced with helicase C domain 1	0.048	Mouse Worm
Uba7	ubiquitin-like modifier activating enzyme 7	0.047
Cyld	cylindromatosis (turban tumor syndrome)	0.046
Stat6	signal transducer and activator of transcription 6	0.046	Mouse
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.045
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.045
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.044
Dtx3l	deltex 3-like (Drosophila)	0.044
Hsf2	heat shock factor 2	0.042
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.041
Trim32	tripartite motif-containing 32	0.040
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.040
Tapbp	TAP binding protein	0.040
Vdr	vitamin D receptor	0.040
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.039
Sykb	spleen tyrosine kinase	0.039
Irf1	interferon regulatory factor 1	0.039	Mouse
Socs3	suppressor of cytokine signaling 3	0.038
Junb	Jun-B oncogene	0.036
Erap1	endoplasmic reticulum aminopeptidase 1	0.035
Fadd	Fas (TNFRSF6)-associated via death domain	0.033
Lin28b	lin-28 homolog B (C. elegans)	0.032	Human
Gbp3	guanylate binding protein 3	0.032
Gbp7	guanylate binding protein 7	0.032
Tifa	TRAF-interacting protein with forkhead-associated domain	0.032
Il1a	interleukin 1 alpha	0.032	Zebrafish
Rel	reticuloendotheliosis oncogene	0.032
Plcg2	phospholipase C, gamma 2	0.031
Clec4n	C-type lectin domain family 4, member n	0.031
Mx2	myxovirus (influenza virus) resistance 2	0.031
Dlg4	discs, large homolog 4 (Drosophila)	0.031
Icam1	intercellular adhesion molecule 1	0.030
Zfp36	zinc finger protein 36	0.030
Tor3a	torsin family 3, member A	0.029
Lgals9	lectin, galactose binding, soluble 9	0.029
Oas2	2'-5' oligoadenylate synthetase 2	0.029
Cxcl10	chemokine (C-X-C motif) ligand 10	0.028
Casp8	caspase 8	0.027
Foxn1	forkhead box N1	0.026
Pml	promyelocytic leukemia	0.026
Mx1	myxovirus (influenza virus) resistance 1	0.025
Il7	interleukin 7	0.025
Mlkl	mixed lineage kinase domain-like	0.024
Jak3	Janus kinase 3	0.024
Traf3	TNF receptor-associated factor 3	0.024
Ifi47	interferon gamma inducible protein 47	0.024
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.024
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.024
Znfx1	zinc finger, NFX1-type containing 1	0.024
Tlr2	toll-like receptor 2	0.023
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.023
Icos	inducible T-cell co-stimulator	0.023
Trp53	transformation related protein 53	0.023
Sqstm1	sequestosome 1	0.023
Irf8	interferon regulatory factor 8	0.022	Mouse
Ccl4	chemokine (C-C motif) ligand 4	0.022
Homer1	homer homolog 1 (Drosophila)	0.022
Lepr	leptin receptor	0.022
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.022
Mavs	mitochondrial antiviral signaling protein	0.022	Human
Herc6	hect domain and RLD 6	0.022
Mapk1	mitogen-activated protein kinase 1	0.022
Cxcl2	chemokine (C-X-C motif) ligand 2	0.022
Adar	adenosine deaminase, RNA-specific	0.021
Il17ra	interleukin 17 receptor A	0.021
Il16	interleukin 16	0.021
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.021
Tnip1	TNFAIP3 interacting protein 1	0.021
Socs1	suppressor of cytokine signaling 1	0.021
Traf2	TNF receptor-associated factor 2	0.020
Dlg2	discs, large homolog 2 (Drosophila)	0.020
Ooep	oocyte expressed protein homolog (dog)	0.020
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.020
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.020
Trafd1	TRAF type zinc finger domain containing 1	0.020
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.020
Birc3	baculoviral IAP repeat-containing 3	0.019
Parp12	poly (ADP-ribose) polymerase family, member 12	0.019	Mouse
Ifnar2	interferon (alpha and beta) receptor 2	0.019
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.019	Mouse
Il12b	interleukin 12b	0.019
Tgtp2	T-cell specific GTPase 2	0.019
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.018
Il4	interleukin 4	0.018
Il6	interleukin 6	0.018
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.018
Metap2	methionine aminopeptidase 2	0.018
Siglece	sialic acid binding Ig-like lectin E	0.018
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.018
Shisa5	shisa homolog 5 (Xenopus laevis)	0.018
Grm1	glutamate receptor, metabotropic 1	0.018
Tnpo3	transportin 3	0.018
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.017
Gbp5	guanylate binding protein 5	0.017
Ikbkg	inhibitor of kappaB kinase gamma	0.017
Bst2	bone marrow stromal cell antigen 2	0.017
Blnk	B-cell linker	0.017
Nckap1l	NCK associated protein 1 like	0.017
Drosha	drosha, ribonuclease type III	0.017
Ccr7	chemokine (C-C motif) receptor 7	0.017
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.017
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.017
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.017
Ccl2	chemokine (C-C motif) ligand 2	0.017
Irg1	immunoresponsive gene 1	0.017
Tmem173	transmembrane protein 173	0.017
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.017
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.016
Flt3	FMS-like tyrosine kinase 3	0.016
Samd9l	sterile alpha motif domain containing 9-like	0.016
Prkcc	protein kinase C, gamma	0.016
Zc3h12a	zinc finger CCCH type containing 12A	0.016
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.016
Ptgs2	prostaglandin-endoperoxide synthase 2	0.016
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.016
Cd14	CD14 antigen	0.015
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.015
H2-D1	histocompatibility 2, D region locus 1	0.015
Pim1	proviral integration site 1	0.015
Lin28a	lin-28 homolog A (C. elegans)	0.015
Rnf135	ring finger protein 135	0.015
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.015
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.015
Gsdmd	gasdermin D	0.015
Irf4	interferon regulatory factor 4	0.015	Mouse
Cblb	Casitas B-lineage lymphoma b	0.015
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.015
Bcl6	B-cell leukemia/lymphoma 6	0.014
Pabpn1	poly(A) binding protein, nuclear 1	0.014
Slc12a1	solute carrier family 12, member 1	0.014
Esr1	estrogen receptor 1 (alpha)	0.014
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.014
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.014	Rat
Cxcl1	chemokine (C-X-C motif) ligand 1	0.014
Itch	itchy, E3 ubiquitin protein ligase	0.014
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.014	Rat
H2-K1	histocompatibility 2, K1, K region	0.014
Ccl3	chemokine (C-C motif) ligand 3	0.014
Prkcd	protein kinase C, delta	0.014
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.014
Lta	lymphotoxin A	0.014	Zebrafish
Il12a	interleukin 12a	0.014
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.014
Atr	ataxia telangiectasia and Rad3 related	0.014
Arc	activity regulated cytoskeletal-associated protein	0.014
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.014
Fkbp3	FK506 binding protein 3	0.013
Rag2	recombination activating gene 2	0.013
Trim26	tripartite motif-containing 26	0.013
Sp100	nuclear antigen Sp100	0.013
Aim2	absent in melanoma 2	0.013
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.013
Gjb2	gap junction protein, beta 2	0.013
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.013
Peli2	pellino 2	0.013
Dusp6	dual specificity phosphatase 6	0.013
Stx11	syntaxin 11	0.012
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.012
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.012
Notch2	Notch gene homolog 2 (Drosophila)	0.012
Cd72	CD72 antigen	0.012
Nmi	N-myc (and STAT) interactor	0.012
Tmem106a	transmembrane protein 106A	0.012
Kcns1	K+ voltage-gated channel, subfamily S, 1	0.012
Ftsj3	FtsJ homolog 3 (E. coli)	0.012
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.012
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.012
Cd86	CD86 antigen	0.012
Cd274	CD274 antigen	0.012
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.012
Rnf19b	ring finger protein 19B	0.012
Ccl22	chemokine (C-C motif) ligand 22	0.011
Pabpc1	poly(A) binding protein, cytoplasmic 1	0.011
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.011
Samhd1	SAM domain and HD domain, 1	0.011
Slc15a3	solute carrier family 15, member 3	0.011
Ankfy1	ankyrin repeat and FYVE domain containing 1	0.011
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.011
Traf1	TNF receptor-associated factor 1	0.011
Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	0.011
Grid2	glutamate receptor, ionotropic, delta 2	0.011
Cd4	CD4 antigen	0.011
Hist1h1t	histone cluster 1, H1t	0.011
Btk	Bruton agammaglobulinemia tyrosine kinase	0.011
Trim34a	tripartite motif-containing 34A	0.011
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.011
Zc3hav1	zinc finger CCCH type, antiviral 1	0.011
Npas1	neuronal PAS domain protein 1	0.011
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.011
Oas3	2'-5' oligoadenylate synthetase 3	0.011
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.011
Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.011
Tor1aip1	torsin A interacting protein 1	0.011
Ebi3	Epstein-Barr virus induced gene 3	0.011
Srrm4	serine/arginine repetitive matrix 4	0.011
Pparg	peroxisome proliferator activated receptor gamma	0.010
Rasgrp1	RAS guanyl releasing protein 1	0.010
Runx1	runt related transcription factor 1	0.010
Mefv	Mediterranean fever	0.010
Fasl	Fas ligand (TNF superfamily, member 6)	0.010
Ly6e	lymphocyte antigen 6 complex, locus E	0.010
Trim30d	tripartite motif-containing 30D	0.010