IMP
Process View
regulation of cardiac muscle hypertrophy
Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cardiac muscle hypertrophy"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ednra | endothelin receptor type A | 0.454 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.445 | ||
| Gdf5 | growth differentiation factor 5 | 0.164 | Mouse | |
| Vegfa | vascular endothelial growth factor A | 0.152 | ||
| Prrx1 | paired related homeobox 1 | 0.090 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.071 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.070 | ||
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.062 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.060 | ||
| Vdr | vitamin D receptor | 0.055 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.050 | ||
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.048 | ||
| Pthlh | parathyroid hormone-like peptide | 0.048 | ||
| Ctsk | cathepsin K | 0.046 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.046 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.046 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.045 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.044 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.040 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.040 | ||
| Col14a1 | collagen, type XIV, alpha 1 | 0.035 | ||
| Ptrf | polymerase I and transcript release factor | 0.034 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.034 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.033 | ||
| Ednrb | endothelin receptor type B | 0.033 | ||
| Kcnk2 | potassium channel, subfamily K, member 2 | 0.033 | ||
| Lmna | lamin A | 0.031 | ||
| Svep1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.030 | ||
| Ppp1r9b | protein phosphatase 1, regulatory subunit 9B | 0.030 | ||
| Apc | adenomatosis polyposis coli | 0.028 | ||
| Hivep2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.028 | ||
| Ghr | growth hormone receptor | 0.026 | ||
| Thbs2 | thrombospondin 2 | 0.026 | ||
| Kif5b | kinesin family member 5B | 0.024 | ||
| Scn7a | sodium channel, voltage-gated, type VII, alpha | 0.023 | ||
| Tnxb | tenascin XB | 0.023 | ||
| Msx1 | homeobox, msh-like 1 | 0.023 | ||
| Dmd | dystrophin, muscular dystrophy | 0.022 | ||
| Sox18 | SRY-box containing gene 18 | 0.022 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.022 | ||
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.021 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.020 | ||
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.020 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.020 | ||
| Mtap2 | microtubule-associated protein 2 | 0.019 | ||
| Ash1l | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.019 | ||
| Mkl2 | MKL/myocardin-like 2 | 0.019 | ||
| Mef2a | myocyte enhancer factor 2A | 0.019 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.019 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.018 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.018 | ||
| Gdf6 | growth differentiation factor 6 | 0.017 | Mouse | |
| Gdf9 | growth differentiation factor 9 | 0.017 | ||
| Siah2 | seven in absentia 2 | 0.017 | ||
| Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.017 | ||
| Lepr | leptin receptor | 0.017 | ||
| Fgf1 | fibroblast growth factor 1 | 0.017 | ||
| Dpt | dermatopontin | 0.017 | ||
| Tbx1 | T-box 1 | 0.017 | ||
| Celf2 | CUGBP, Elav-like family member 2 | 0.016 | ||
| Fmn1 | formin 1 | 0.016 | ||
| Prkaca | protein kinase, cAMP dependent, catalytic, alpha | 0.016 | ||
| Gabrr1 | gamma-aminobutyric acid (GABA) C receptor, subunit rho 1 | 0.016 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.016 | ||
| Prkar2a | protein kinase, cAMP dependent regulatory, type II alpha | 0.015 | ||
| Abcc9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 0.015 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.015 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.015 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.015 | ||
| Lama2 | laminin, alpha 2 | 0.014 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.014 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.014 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.014 | ||
| Nppb | natriuretic peptide type B | 0.014 | ||
| Foxi3 | forkhead box I3 | 0.014 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.014 | ||
| Sox9 | SRY-box containing gene 9 | 0.014 | ||
| Tdgf1 | teratocarcinoma-derived growth factor 1 | 0.014 | ||
| Sparcl1 | SPARC-like 1 | 0.013 | ||
| Bmper | BMP-binding endothelial regulator | 0.013 | ||
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.013 | ||
| Pax2 | paired box gene 2 | 0.013 | ||
| Espn | espin | 0.013 | ||
| Tbx15 | T-box 15 | 0.013 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.013 | ||
| Snx13 | sorting nexin 13 | 0.013 | ||
| Cnn1 | calponin 1 | 0.012 | ||
| Cacna1h | calcium channel, voltage-dependent, T type, alpha 1H subunit | 0.012 | ||
| Runx2 | runt related transcription factor 2 | 0.012 | ||
| Fam49b | family with sequence similarity 49, member B | 0.012 | ||
| Fkbp3 | FK506 binding protein 3 | 0.012 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.012 | ||
| Myo5a | myosin VA | 0.012 | ||
| Axin1 | axin 1 | 0.012 | ||
| Vav3 | vav 3 oncogene | 0.012 | ||
| Dpep1 | dipeptidase 1 (renal) | 0.012 | ||
| Lhx1 | LIM homeobox protein 1 | 0.012 | ||
| Rara | retinoic acid receptor, alpha | 0.012 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.011 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.011 | ||
| Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.011 | ||
| Drd2 | dopamine receptor D2 | 0.011 | ||
| Ush1g | Usher syndrome 1G homolog (human) | 0.011 | ||
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.011 | ||
| Eltd1 | EGF, latrophilin seven transmembrane domain containing 1 | 0.011 | ||
| Adamts2 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 | 0.011 | ||
| Gdf1 | growth differentiation factor 1 | 0.011 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.011 | ||
| Smoc2 | SPARC related modular calcium binding 2 | 0.011 | ||
| Serpinf1 | serine (or cysteine) peptidase inhibitor, clade F, member 1 | 0.010 | ||
| Adra1b | adrenergic receptor, alpha 1b | 0.010 | ||
| Ptprm | protein tyrosine phosphatase, receptor type, M | 0.010 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.010 | ||
| Tbr1 | T-box brain gene 1 | 0.010 |