IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

negative regulation of ubiquitin protein transferase activity

GO:0051444

Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of ubiquitin protein transferase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of ubiquitin protein transferase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.989
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.855	Yeast
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.799
Lrrk2	leucine-rich repeat kinase 2	0.773
Notch1	Notch gene homolog 1 (Drosophila)	0.519
Ncstn	nicastrin	0.480
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.428
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.419	Yeast
Psen1	presenilin 1	0.378
Ccne2	cyclin E2	0.324	Fly
Cdk2	cyclin-dependent kinase 2	0.320
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.297	Yeast
Rpgrip1l	Rpgrip1-like	0.259
Notch2	Notch gene homolog 2 (Drosophila)	0.207
Trp53	transformation related protein 53	0.183
Sgol2	shugoshin-like 2 (S. pombe)	0.170
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.149
Ptk2	PTK2 protein tyrosine kinase 2	0.142
Axin1	axin 1	0.119
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.116
App	amyloid beta (A4) precursor protein	0.107
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.105
Birc5	baculoviral IAP repeat-containing 5	0.095
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.072
Purb	purine rich element binding protein B	0.071
Ect2	ect2 oncogene	0.070
Iqcb1	IQ calmodulin-binding motif containing 1	0.064
Anln	anillin, actin binding protein	0.064
Ncapg2	non-SMC condensin II complex, subunit G2	0.063
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.061
Cetn3	centrin 3	0.061
Psen2	presenilin 2	0.055
Irf6	interferon regulatory factor 6	0.052
Skp2	S-phase kinase-associated protein 2 (p45)	0.052
Trp73	transformation related protein 73	0.050
Ccne1	cyclin E1	0.049	Fly
Bad	BCL2-associated agonist of cell death	0.047
Dck	deoxycytidine kinase	0.047
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.047
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.044
Apc	adenomatosis polyposis coli	0.044
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.035
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.035
Erlin2	ER lipid raft associated 2	0.033
Glrx3	glutaredoxin 3	0.029
Tbc1d4	TBC1 domain family, member 4	0.029
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.029
Sh3bp1	SH3-domain binding protein 1	0.027
Tsc1	tuberous sclerosis 1	0.027
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.026	Yeast
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.026
Ccdc99	coiled-coil domain containing 99	0.024
Ripk4	receptor-interacting serine-threonine kinase 4	0.023
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.023
Gmnn	geminin	0.022
Htt	huntingtin	0.022
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.022
Mdm2	transformed mouse 3T3 cell double minute 2	0.021
Rps16	ribosomal protein S16	0.021
Sgol1	shugoshin-like 1 (S. pombe)	0.021
Zbtb7a	zinc finger and BTB domain containing 7a	0.021
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.021
Mapk13	mitogen-activated protein kinase 13	0.020
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.020
Kif22	kinesin family member 22	0.020
4930579G24Rik	RIKEN cDNA 4930579G24 gene	0.019
Itga3	integrin alpha 3	0.019
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.018
Hspa8	heat shock protein 8	0.018
Eno1	enolase 1, alpha non-neuron	0.018
Lrp6	low density lipoprotein receptor-related protein 6	0.018
Ptch1	patched homolog 1	0.018
Acly	ATP citrate lyase	0.018
Fkbp1a	FK506 binding protein 1a	0.018
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.018
Rrm2	ribonucleotide reductase M2	0.017
Cenpq	centromere protein Q	0.017
Eef1g	eukaryotic translation elongation factor 1 gamma	0.017
Xpa	xeroderma pigmentosum, complementation group A	0.017
Ttk	Ttk protein kinase	0.017
Rap2a	RAS related protein 2a	0.017
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.017
4632434I11Rik	RIKEN cDNA 4632434I11 gene	0.016
Psenen	presenilin enhancer 2 homolog (C. elegans)	0.016
Tsc2	tuberous sclerosis 2	0.016
Shcbp1	Shc SH2-domain binding protein 1	0.016
Gpr152	G protein-coupled receptor 152	0.016
Hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.016
Htatip2	HIV-1 tat interactive protein 2, homolog (human)	0.015
Psmd11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.015
Depdc1a	DEP domain containing 1a	0.015
E2f1	E2F transcription factor 1	0.015
Actr1a	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.015
Mrpl11	mitochondrial ribosomal protein L11	0.015
H2afz	H2A histone family, member Z	0.014
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.014
Hmgb2	high mobility group box 2	0.014
Ccna2	cyclin A2	0.014
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.013
Impa1	inositol (myo)-1(or 4)-monophosphatase 1	0.013
Fkbp3	FK506 binding protein 3	0.013
Fus	fusion, derived from t(12;16) malignant liposarcoma (human)	0.013
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.013
Bcar1	breast cancer anti-estrogen resistance 1	0.013
Emx1	empty spiracles homolog 1 (Drosophila)	0.013
Mdm4	transformed mouse 3T3 cell double minute 4	0.013
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.013
Cenpc1	centromere protein C1	0.013
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
Hist1h1a	histone cluster 1, H1a	0.012
Src	Rous sarcoma oncogene	0.012
Lin9	lin-9 homolog (C. elegans)	0.012
Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4	0.012
E2f7	E2F transcription factor 7	0.012
Tuba1a	tubulin, alpha 1A	0.012
Fasn	fatty acid synthase	0.012
Lrrc46	leucine rich repeat containing 46	0.012
Tacstd2	tumor-associated calcium signal transducer 2	0.011
Ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.011
En1	engrailed 1	0.011
Cdc123	cell division cycle 123 homolog (S. cerevisiae)	0.011
Mrps25	mitochondrial ribosomal protein S25	0.011
Defa4	defensin, alpha, 4	0.011
Stk11	serine/threonine kinase 11	0.011
Prkce	protein kinase C, epsilon	0.011
Ldlr	low density lipoprotein receptor	0.011
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.011
2810428I15Rik	RIKEN cDNA 2810428I15 gene	0.011
Bsn	bassoon	0.011
N6amt2	N-6 adenine-specific DNA methyltransferase 2 (putative)	0.011
Raf1	v-raf-leukemia viral oncogene 1	0.011
Phlda2	pleckstrin homology-like domain, family A, member 2	0.011
Pkp3	plakophilin 3	0.011
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.011
Stmn1	stathmin 1	0.010
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.010
Gcsh	glycine cleavage system protein H (aminomethyl carrier)	0.010
Aurka	aurora kinase A	0.010
Stil	Scl/Tal1 interrupting locus	0.010
1700011F14Rik	RIKEN cDNA 1700011F14 gene	0.010