IMP: Integrative Multi-species Prediction

Mus musculus

2 genes annotated in mouse

Multi-species View

positive regulation of cardiac muscle contraction

GO:0060452

Any process that increases the frequency, rate or extent of cardiac muscle contraction.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cardiac muscle contraction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of cardiac muscle contraction" (in gray)

Name	Description	Probability	Func Analog Organism
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.864
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.783
Hspa8	heat shock protein 8	0.713
Hsph1	heat shock 105kDa/110kDa protein 1	0.711
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.445
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.245
Cacybp	calcyclin binding protein	0.204
Casq2	calsequestrin 2	0.172
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.166
Itgb1bp2	integrin beta 1 binding protein 2	0.164
Pthlh	parathyroid hormone-like peptide	0.149
Hspa5	heat shock protein 5	0.134
Scn1a	sodium channel, voltage-gated, type I, alpha	0.122
Cyr61	cysteine rich protein 61	0.098
Iqcb1	IQ calmodulin-binding motif containing 1	0.086
Hspd1	heat shock protein 1 (chaperonin)	0.085
Fgf9	fibroblast growth factor 9	0.085
Scn5a	sodium channel, voltage-gated, type V, alpha	0.082
Adra1b	adrenergic receptor, alpha 1b	0.081
Darc	Duffy blood group, chemokine receptor	0.080
Bzw1	basic leucine zipper and W2 domains 1	0.080
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.080
Ahi1	Abelson helper integration site 1	0.079
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.076
Ldb3	LIM domain binding 3	0.071
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.064
Actn2	actinin alpha 2	0.063
Ly86	lymphocyte antigen 86	0.060
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.058
Fam105a	family with sequence similarity 105, member A	0.057
Rasa3	RAS p21 protein activator 3	0.056
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.056
Ednrb	endothelin receptor type B	0.056
Coro1a	coronin, actin binding protein 1A	0.056
Fkbp1b	FK506 binding protein 1b	0.053
Oprl1	opioid receptor-like 1	0.052
Cct6a	chaperonin containing Tcp1, subunit 6a (zeta)	0.051
Ptprb	protein tyrosine phosphatase, receptor type, B	0.050
Prkcb	protein kinase C, beta	0.050
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.050
Gja1	gap junction protein, alpha 1	0.050
Gpr83	G protein-coupled receptor 83	0.049
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.048
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.046
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.044
Fgf13	fibroblast growth factor 13	0.042
Prox1	prospero-related homeobox 1	0.041
Timp3	tissue inhibitor of metalloproteinase 3	0.041
Hspa4l	heat shock protein 4 like	0.040
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.040
Camk4	calcium/calmodulin-dependent protein kinase IV	0.038
Srpk3	serine/arginine-rich protein specific kinase 3	0.038
Frmd5	FERM domain containing 5	0.037
Tcap	titin-cap	0.037
Sparcl1	SPARC-like 1	0.036
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.036
Nop58	NOP58 ribonucleoprotein homolog (yeast)	0.035
Cox8b	cytochrome c oxidase, subunit VIIIb	0.035
Zfpm2	zinc finger protein, multitype 2	0.034
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.033
Cd83	CD83 antigen	0.033
Dtna	dystrobrevin alpha	0.032
Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	0.032
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.032
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.031
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.031
Col19a1	collagen, type XIX, alpha 1	0.030
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.030
Rgs7	regulator of G protein signaling 7	0.030
Twf2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.030
S100a4	S100 calcium binding protein A4	0.029
Popdc3	popeye domain containing 3	0.029
Zc3h15	zinc finger CCCH-type containing 15	0.028
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.028
Rhoj	ras homolog gene family, member J	0.028
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.028
Adcy7	adenylate cyclase 7	0.027
Anxa3	annexin A3	0.027
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.027
Ncan	neurocan	0.026
Creld2	cysteine-rich with EGF-like domains 2	0.026
Lamp3	lysosomal-associated membrane protein 3	0.025
Ptpro	protein tyrosine phosphatase, receptor type, O	0.025
Kctd12	potassium channel tetramerisation domain containing 12	0.024
Dusp1	dual specificity phosphatase 1	0.024
Gad2	glutamic acid decarboxylase 2	0.024
Tuba4a	tubulin, alpha 4A	0.024
Dynll1	dynein light chain LC8-type 1	0.024
Lrrk2	leucine-rich repeat kinase 2	0.024
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.024
Oprm1	opioid receptor, mu 1	0.023
Arrb2	arrestin, beta 2	0.023
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.023
Cul9	cullin 9	0.023
Myom1	myomesin 1	0.023
Cdh13	cadherin 13	0.023
Lpar1	lysophosphatidic acid receptor 1	0.023
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.023
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.022
Fermt3	fermitin family homolog 3 (Drosophila)	0.022
Hrc	histidine rich calcium binding protein	0.022
Rgs4	regulator of G-protein signaling 4	0.022	Mouse
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.021
Bche	butyrylcholinesterase	0.021
Odz1	odd Oz/ten-m homolog 1 (Drosophila)	0.021
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.021
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.021
Tuba8	tubulin, alpha 8	0.020
Akt1	thymoma viral proto-oncogene 1	0.020
Rpgrip1l	Rpgrip1-like	0.020
Ccdc109b	coiled-coil domain containing 109B	0.020
Morf4l2	mortality factor 4 like 2	0.020
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.020
Ckmt2	creatine kinase, mitochondrial 2	0.020
Egr2	early growth response 2	0.020
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.020
Fli1	Friend leukemia integration 1	0.019
Fos	FBJ osteosarcoma oncogene	0.019
Sez6	seizure related gene 6	0.019
Stip1	stress-induced phosphoprotein 1	0.019
Lxn	latexin	0.019
Wipf1	WAS/WASL interacting protein family, member 1	0.019
Gpr37	G protein-coupled receptor 37	0.019
F3	coagulation factor III	0.019
Syt1	synaptotagmin I	0.019
Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8	0.018
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.018
Cryab	crystallin, alpha B	0.018
Errfi1	ERBB receptor feedback inhibitor 1	0.018
Evl	Ena-vasodilator stimulated phosphoprotein	0.018
Gm6788	predicted gene 6788	0.018
Prrx1	paired related homeobox 1	0.018
Fgfrl1	fibroblast growth factor receptor-like 1	0.018
Myl1	myosin, light polypeptide 1	0.018
Gng10	guanine nucleotide binding protein (G protein), gamma 10	0.018
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.017
Trpv2	transient receptor potential cation channel, subfamily V, member 2	0.017
Nsg2	neuron specific gene family member 2	0.017
Myom2	myomesin 2	0.017
Tnnc1	troponin C, cardiac/slow skeletal	0.017
Dcn	decorin	0.017
Tbx5	T-box 5	0.017
Eif2s2	eukaryotic translation initiation factor 2, subunit 2 (beta)	0.017
Acta1	actin, alpha 1, skeletal muscle	0.017
Matk	megakaryocyte-associated tyrosine kinase	0.017
Akap2	A kinase (PRKA) anchor protein 2	0.017
St6galnac5	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	0.017
Rgs6	regulator of G-protein signaling 6	0.017
Zfp385a	zinc finger protein 385A	0.017
Cpne6	copine VI	0.017
Plxna2	plexin A2	0.016
Scg2	secretogranin II	0.016
LOC100502924	hypothetical protein LOC100502924	0.016
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.016
Gdpd5	glycerophosphodiester phosphodiesterase domain containing 5	0.016
Hspa1a	heat shock protein 1A	0.016
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.016
Cntn3	contactin 3	0.016
Samd4	sterile alpha motif domain containing 4	0.016
Cntn1	contactin 1	0.016
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.016
Nrgn	neurogranin	0.016
Ahsa2	AHA1, activator of heat shock protein ATPase homolog 2 (yeast)	0.016
Iqcj-schip1	IQ motif containing J-schwannomin interacting protein 1 readthrough	0.016
Hpca	hippocalcin	0.016
Pvalb	parvalbumin	0.016
Mapk10	mitogen-activated protein kinase 10	0.016
Nefm	neurofilament, medium polypeptide	0.016
Baz1a	bromodomain adjacent to zinc finger domain 1A	0.016
Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.016
Ltk	leukocyte tyrosine kinase	0.016
Ubxn4	UBX domain protein 4	0.016
Kcna7	potassium voltage-gated channel, shaker-related subfamily, member 7	0.016
Sgk1	serum/glucocorticoid regulated kinase 1	0.016
Fermt2	fermitin family homolog 2 (Drosophila)	0.016
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.016
Mef2c	myocyte enhancer factor 2C	0.015
Csrp3	cysteine and glycine-rich protein 3	0.015
Gdap1	ganglioside-induced differentiation-associated-protein 1	0.015
Wwtr1	WW domain containing transcription regulator 1	0.015
Ryr3	ryanodine receptor 3	0.015	Mouse
Nts	neurotensin	0.015
Tm6sf1	transmembrane 6 superfamily member 1	0.015
Fosb	FBJ osteosarcoma oncogene B	0.015
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.015
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.015
Fxyd5	FXYD domain-containing ion transport regulator 5	0.015
Rxrg	retinoid X receptor gamma	0.015
Mtap1b	microtubule-associated protein 1B	0.015
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.015
Fhl2	four and a half LIM domains 2	0.015
Capn3	calpain 3	0.015
Rgs10	regulator of G-protein signalling 10	0.015	Mouse
Cav3	caveolin 3	0.015
Actg1	actin, gamma, cytoplasmic 1	0.014
Astn1	astrotactin 1	0.014
Fam65b	family with sequence similarity 65, member B	0.014
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.014
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.014
Tubb5	tubulin, beta 5	0.014
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.014
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.014
Hspb3	heat shock protein 3	0.014
Kalrn	kalirin, RhoGEF kinase	0.014
Gad1	glutamic acid decarboxylase 1	0.014
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.014
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.014
Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.014
Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	0.014
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.014
Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	0.014
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.014
Calm1	calmodulin 1	0.014
Tnnt2	troponin T2, cardiac	0.014
Flt1	FMS-like tyrosine kinase 1	0.014
Gpr34	G protein-coupled receptor 34	0.013
Cklf	chemokine-like factor	0.013
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.013
Slco5a1	solute carrier organic anion transporter family, member 5A1	0.013
Laptm5	lysosomal-associated protein transmembrane 5	0.013
Sdpr	serum deprivation response	0.013
Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	0.013
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.013
Prkcc	protein kinase C, gamma	0.013
Ptprm	protein tyrosine phosphatase, receptor type, M	0.013
Hbegf	heparin-binding EGF-like growth factor	0.013
Ccrl1	chemokine (C-C motif) receptor-like 1	0.013
Pdia3	protein disulfide isomerase associated 3	0.013
Trpc3	transient receptor potential cation channel, subfamily C, member 3	0.013
Edn1	endothelin 1	0.013
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.013
Emcn	endomucin	0.013
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.013
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.013
Bag2	BCL2-associated athanogene 2	0.013
Xirp1	xin actin-binding repeat containing 1	0.013
Hpcal1	hippocalcin-like 1	0.013
Postn	periostin, osteoblast specific factor	0.013
Gng2	guanine nucleotide binding protein (G protein), gamma 2	0.013
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.013
Cmtm3	CKLF-like MARVEL transmembrane domain containing 3	0.013
Tnc	tenascin C	0.013
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.013
Dio2	deiodinase, iodothyronine, type II	0.013
Cd48	CD48 antigen	0.013
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.013
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.013
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.012
Pygm	muscle glycogen phosphorylase	0.012
Klf4	Kruppel-like factor 4 (gut)	0.012
Vip	vasoactive intestinal polypeptide	0.012
Gpr37l1	G protein-coupled receptor 37-like 1	0.012
Casq1	calsequestrin 1	0.012
Scg3	secretogranin III	0.012
Tra2a	transformer 2 alpha homolog (Drosophila)	0.012
Edn2	endothelin 2	0.012
Kif5c	kinesin family member 5C	0.012
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.012
Cckbr	cholecystokinin B receptor	0.012
Cxcr7	chemokine (C-X-C motif) receptor 7	0.012
Tubb6	tubulin, beta 6	0.012
Nid1	nidogen 1	0.012
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.012
Sox5	SRY-box containing gene 5	0.012
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.012
Ntsr2	neurotensin receptor 2	0.012
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.012
Thy1	thymus cell antigen 1, theta	0.012
Cxcl2	chemokine (C-X-C motif) ligand 2	0.012
Hspa1b	heat shock protein 1B	0.012
Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	0.012
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.012
Cotl1	coactosin-like 1 (Dictyostelium)	0.012
Bai1	brain-specific angiogenesis inhibitor 1	0.012
Rhob	ras homolog gene family, member B	0.012
Lrrc2	leucine rich repeat containing 2	0.011
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.011
Ptprn	protein tyrosine phosphatase, receptor type, N	0.011
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.011
Nrap	nebulin-related anchoring protein	0.011
Fgf1	fibroblast growth factor 1	0.011
Fgf12	fibroblast growth factor 12	0.011
Tuba1b	tubulin, alpha 1B	0.011
Arhgap9	Rho GTPase activating protein 9	0.011
Gpm6b	glycoprotein m6b	0.011
Cd200	CD200 antigen	0.011
Pak3	p21 protein (Cdc42/Rac)-activated kinase 3	0.011
Tff1	trefoil factor 1	0.011
Nav3	neuron navigator 3	0.011
Plekho1	pleckstrin homology domain containing, family O member 1	0.011
Myt1	myelin transcription factor 1	0.011
Lag3	lymphocyte-activation gene 3	0.011
Arl4c	ADP-ribosylation factor-like 4C	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Rab33a	RAB33A, member of RAS oncogene family	0.011
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.011
Tnnc2	troponin C2, fast	0.011
Tubb2a	tubulin, beta 2A	0.011
Tnni2	troponin I, skeletal, fast 2	0.011
Lama2	laminin, alpha 2	0.011
Klhl6	kelch-like 6 (Drosophila)	0.011
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.011
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.011
Gh	growth hormone	0.011
Vtn	vitronectin	0.011
AI413582	expressed sequence AI413582	0.011
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.011
Scn8a	sodium channel, voltage-gated, type VIII, alpha	0.011
Cxcl1	chemokine (C-X-C motif) ligand 1	0.011
Tnnt1	troponin T1, skeletal, slow	0.011
Palmd	palmdelphin	0.011
Rgs5	regulator of G-protein signaling 5	0.011	Mouse
Akap12	A kinase (PRKA) anchor protein (gravin) 12	0.011
Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.011
Tra2b	transformer 2 beta homolog (Drosophila)	0.011
Fez1	fasciculation and elongation protein zeta 1 (zygin I)	0.011
Thbd	thrombomodulin	0.011
Tspan2	tetraspanin 2	0.011
Ptplad2	protein tyrosine phosphatase-like A domain containing 2	0.011
Hopx	HOP homeobox	0.011
Akr1b3	aldo-keto reductase family 1, member B3 (aldose reductase)	0.011
Ppm1m	protein phosphatase 1M	0.011
E130012A19Rik	RIKEN cDNA E130012A19 gene	0.011
Neurod1	neurogenic differentiation 1	0.011
Slco1c1	solute carrier organic anion transporter family, member 1c1	0.011
Tnnt3	troponin T3, skeletal, fast	0.011
Mlf1	myeloid leukemia factor 1	0.011
Aif1	allograft inflammatory factor 1	0.011
Nrl	neural retina leucine zipper gene	0.010
Adarb1	adenosine deaminase, RNA-specific, B1	0.010
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.010
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.010
Rasl10b	RAS-like, family 10, member B	0.010
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.010
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.010
Plin5	perilipin 5	0.010
Mobkl2a	MOB1, Mps One Binder kinase activator-like 2A (yeast)	0.010
Scrg1	scrapie responsive gene 1	0.010
Adam22	a disintegrin and metallopeptidase domain 22	0.010
Sla	src-like adaptor	0.010
Pgam2	phosphoglycerate mutase 2	0.010
Pmp22	peripheral myelin protein 22	0.010
Ripk3	receptor-interacting serine-threonine kinase 3	0.010
Lpxn	leupaxin	0.010
Tek	endothelial-specific receptor tyrosine kinase	0.010
Iqsec3	IQ motif and Sec7 domain 3	0.010
Tmod1	tropomodulin 1	0.010
Cd69	CD69 antigen	0.010