IMP: Integrative Multi-species Prediction

Mus musculus

5 genes annotated in mouse

tricarboxylic acid metabolic process

The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tricarboxylic acid metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "tricarboxylic acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Aco2	aconitase 2, mitochondrial	0.960	Human Rat
Stat5a	signal transducer and activator of transcription 5A	0.956
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.915
Stat5b	signal transducer and activator of transcription 5B	0.871
Cs	citrate synthase	0.731
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.662
Mdh2	malate dehydrogenase 2, NAD (mitochondrial)	0.589
Cyc1	cytochrome c-1	0.510
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.486
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.380
Stat3	signal transducer and activator of transcription 3	0.359	Mouse
Lepr	leptin receptor	0.333
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.331
Ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.311
Uqcrc1	ubiquinol-cytochrome c reductase core protein 1	0.301
Irf9	interferon regulatory factor 9	0.276
Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	0.242
Esr1	estrogen receptor 1 (alpha)	0.238
Idh3g	isocitrate dehydrogenase 3 (NAD+), gamma	0.215	Yeast Rat
Foxp3	forkhead box P3	0.199
Trp53	transformation related protein 53	0.155
Dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.128
Sdhc	succinate dehydrogenase complex, subunit C, integral membrane protein	0.119
Prlr	prolactin receptor	0.102	Mouse
Ar	androgen receptor	0.084
Ghr	growth hormone receptor	0.083
Uqcrc2	ubiquinol cytochrome c reductase core protein 2	0.080
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.076
Samm50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.065
Il6st	interleukin 6 signal transducer	0.059
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.057
Fh1	fumarate hydratase 1	0.053
Ndufa10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10	0.052
Stat1	signal transducer and activator of transcription 1	0.051	Mouse
Aldoa	aldolase A, fructose-bisphosphate	0.050
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.048
Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4	0.047
Stat6	signal transducer and activator of transcription 6	0.043	Mouse
Tapbp	TAP binding protein	0.042
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.041
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.040
Il1r1	interleukin 1 receptor, type I	0.040
Pparg	peroxisome proliferator activated receptor gamma	0.039
Sin3a	transcriptional regulator, SIN3A (yeast)	0.038
Slc25a11	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11	0.038
Ogdh	oxoglutarate dehydrogenase (lipoamide)	0.036
Trap1	TNF receptor-associated protein 1	0.036
Ndufb5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5	0.035
1300001I01Rik	RIKEN cDNA 1300001I01 gene	0.034
Vdac1	voltage-dependent anion channel 1	0.033
Trim21	tripartite motif-containing 21	0.032
Gpi1	glucose phosphate isomerase 1	0.032
Ncoa3	nuclear receptor coactivator 3	0.032
Ckap2	cytoskeleton associated protein 2	0.032
Acat1	acetyl-Coenzyme A acetyltransferase 1	0.030
Ndufc2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2	0.029
Got1	glutamate oxaloacetate transaminase 1, soluble	0.029
Kit	kit oncogene	0.029
Tgfb1	transforming growth factor, beta 1	0.029
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.029
Egln3	EGL nine homolog 3 (C. elegans)	0.028
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.028
Cat	catalase	0.027
Igf1	insulin-like growth factor 1	0.025
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.024
Atp5o	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	0.024
Coq9	coenzyme Q9 homolog (yeast)	0.023
Irgm1	immunity-related GTPase family M member 1	0.023
Siah2	seven in absentia 2	0.023
Dlst	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	0.023
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.022
Il10	interleukin 10	0.022
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.022
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.021
Il4ra	interleukin 4 receptor, alpha	0.021
Nfil3	nuclear factor, interleukin 3, regulated	0.021
Immt	inner membrane protein, mitochondrial	0.021
Adar	adenosine deaminase, RNA-specific	0.021
Stat2	signal transducer and activator of transcription 2	0.021	Mouse
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.020
Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7	0.020
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.020
Idh3b	isocitrate dehydrogenase 3 (NAD+) beta	0.019	Rat
Chchd10	coiled-coil-helix-coiled-coil-helix domain containing 10	0.019
Cav1	caveolin 1, caveolae protein	0.019
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.018
Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	0.018
Arid1b	AT rich interactive domain 1B (SWI-like)	0.017
Sdhb	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.017
Lgals9	lectin, galactose binding, soluble 9	0.017
Abcb8	ATP-binding cassette, sub-family B (MDR/TAP), member 8	0.017
Nfs1	nitrogen fixation gene 1 (S. cerevisiae)	0.017
Pnpla2	patatin-like phospholipase domain containing 2	0.017
Tecr	trans-2,3-enoyl-CoA reductase	0.016
Atp5c1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.016
Ifnar2	interferon (alpha and beta) receptor 2	0.016
Hadhb	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	0.016
Parp14	poly (ADP-ribose) polymerase family, member 14	0.016
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.016
Lep	leptin	0.015
Clybl	citrate lyase beta like	0.015
2310061I04Rik	RIKEN cDNA 2310061I04 gene	0.015
Qdpr	quinoid dihydropteridine reductase	0.015
Nckap1l	NCK associated protein 1 like	0.015
Mavs	mitochondrial antiviral signaling protein	0.015
Mta2	metastasis-associated gene family, member 2	0.014
E2f1	E2F transcription factor 1	0.014
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.013
Acadvl	acyl-Coenzyme A dehydrogenase, very long chain	0.013
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.013
Afg3l2	AFG3(ATPase family gene 3)-like 2 (yeast)	0.013
Suclg1	succinate-CoA ligase, GDP-forming, alpha subunit	0.013
Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.013
Myd88	myeloid differentiation primary response gene 88	0.013
Wwox	WW domain-containing oxidoreductase	0.012
Il6	interleukin 6	0.012
Irgm2	immunity-related GTPase family M member 2	0.012
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.012
Pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.012
Coq5	coenzyme Q5 homolog, methyltransferase (yeast)	0.012
Plk1	polo-like kinase 1 (Drosophila)	0.012
Scp2	sterol carrier protein 2, liver	0.012
Aurkb	aurora kinase B	0.011
Gys1	glycogen synthase 1, muscle	0.011
Irs2	insulin receptor substrate 2	0.011
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.011
Ndufab1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1	0.011
Chek2	CHK2 checkpoint homolog (S. pombe)	0.011
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.011
Ndufb6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6	0.011
Vegfb	vascular endothelial growth factor B	0.011
Hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	0.010
Ccnb2	cyclin B2	0.010
Tpi1	triosephosphate isomerase 1	0.010
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.010
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.010
Rhot2	ras homolog gene family, member T2	0.010