IMP: Integrative Multi-species Prediction

Mus musculus

1 genes annotated in mouse

xenobiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "xenobiotic catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "xenobiotic catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Gstm1	glutathione S-transferase, mu 1	0.996	Human
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.991	Rat
Fmo5	flavin containing monooxygenase 5	0.980
Gstm3	glutathione S-transferase, mu 3	0.977	Human Mouse
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.965
Otc	ornithine transcarbamylase	0.965
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.963
Gsta3	glutathione S-transferase, alpha 3	0.959	Rat
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.897
Gstm6	glutathione S-transferase, mu 6	0.833	Human Mouse
Gm3776	predicted gene 3776	0.830	Rat
Gsta4	glutathione S-transferase, alpha 4	0.826
Sult1d1	sulfotransferase family 1D, member 1	0.825
Ces1d	carboxylesterase 1D	0.744
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.660
Ces1g	carboxylesterase 1G	0.630
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.620
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.608	Fly
Cps1	carbamoyl-phosphate synthetase 1	0.588
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.555
Ephx1	epoxide hydrolase 1, microsomal	0.551
Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	0.503	Fly
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.487
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.462	Fly
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.457
Gstt1	glutathione S-transferase, theta 1	0.442
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.399
Gstm4	glutathione S-transferase, mu 4	0.386
Cyp3a41b	cytochrome P450, family 3, subfamily a, polypeptide 41B	0.353	Fly
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.290
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.289
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.287	Fly
Aass	aminoadipate-semialdehyde synthase	0.279
Tmem205	transmembrane protein 205	0.262
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.231
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.226
Defb1	defensin beta 1	0.215
Iyd	iodotyrosine deiodinase	0.214
Adh1	alcohol dehydrogenase 1 (class I)	0.213
Gstm2	glutathione S-transferase, mu 2	0.202	Human Mouse
Sult1b1	sulfotransferase family 1B, member 1	0.192
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.188
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.182
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.167
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.156
Galm	galactose mutarotase	0.139
Ces2g	carboxylesterase 2G	0.138
G6pc	glucose-6-phosphatase, catalytic	0.136
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.133
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.132
Cfhr1	complement factor H-related 1	0.130
S100a1	S100 calcium binding protein A1	0.124
Nqo1	NAD(P)H dehydrogenase, quinone 1	0.122
Dpyd	dihydropyrimidine dehydrogenase	0.121
Vsig4	V-set and immunoglobulin domain containing 4	0.118
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.118
Akr1d1	aldo-keto reductase family 1, member D1	0.116
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.114
Akr1c6	aldo-keto reductase family 1, member C6	0.107
Mgst1	microsomal glutathione S-transferase 1	0.105
Inmt	indolethylamine N-methyltransferase	0.101
Tdo2	tryptophan 2,3-dioxygenase	0.099
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.099
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.097
Pon1	paraoxonase 1	0.094
Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	0.092
Selenbp1	selenium binding protein 1	0.092
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.092	Fly
Rdh7	retinol dehydrogenase 7	0.091
Cmbl	carboxymethylenebutenolidase-like (Pseudomonas)	0.084
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.083
Ces1e	carboxylesterase 1E	0.081
Pxmp2	peroxisomal membrane protein 2	0.080
Cyp3a41a	cytochrome P450, family 3, subfamily a, polypeptide 41A	0.079	Fly
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.075
Gstk1	glutathione S-transferase kappa 1	0.074
Crp	C-reactive protein, pentraxin-related	0.070
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.068
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.067
Bche	butyrylcholinesterase	0.067
Ces2e	carboxylesterase 2E	0.066
Mpzl2	myelin protein zero-like 2	0.063
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.062
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.055
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.054
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.053
Ugt2b35	UDP glucuronosyltransferase 2 family, polypeptide B35	0.051
Pm20d1	peptidase M20 domain containing 1	0.050
Cyp4a12a	cytochrome P450, family 4, subfamily a, polypeptide 12a	0.050
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.048
Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.048
Alb	albumin	0.048
Aldob	aldolase B, fructose-bisphosphate	0.047
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.046
Retsat	retinol saturase (all trans retinol 13,14 reductase)	0.046
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.046
Copz2	coatomer protein complex, subunit zeta 2	0.045
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.044
Nat1	N-acetyl transferase 1	0.044
Bhmt	betaine-homocysteine methyltransferase	0.044
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.044
Akr1b7	aldo-keto reductase family 1, member B7	0.044
Hfe	hemochromatosis	0.043
Gc	group specific component	0.042
Rbp4	retinol binding protein 4, plasma	0.042
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.042
Fmo1	flavin containing monooxygenase 1	0.042
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.041
Kynu	kynureninase (L-kynurenine hydrolase)	0.041
Aox1	aldehyde oxidase 1	0.041
Hao1	hydroxyacid oxidase 1, liver	0.040
Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	0.040
Pcbd1	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1	0.040
Sord	sorbitol dehydrogenase	0.040
Cbr1	carbonyl reductase 1	0.040
Defa15	defensin, alpha, 15	0.040
Gstt3	glutathione S-transferase, theta 3	0.040
D630002G06Rik	RIKEN cDNA D630002G06 gene	0.039
Entpd5	ectonucleoside triphosphate diphosphohydrolase 5	0.038
Ces1f	carboxylesterase 1F	0.038
Cyp2a4	cytochrome P450, family 2, subfamily a, polypeptide 4	0.037
Cd59a	CD59a antigen	0.037
Gstp1	glutathione S-transferase, pi 1	0.037
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.036
Fmo3	flavin containing monooxygenase 3	0.036
F9	coagulation factor IX	0.035
Ces2a	carboxylesterase 2A	0.035
Tst	thiosulfate sulfurtransferase, mitochondrial	0.034
Ddc	dopa decarboxylase	0.034
Gstz1	glutathione transferase zeta 1 (maleylacetoacetate isomerase)	0.033
Mug2	murinoglobulin 2	0.033
Phyh	phytanoyl-CoA hydroxylase	0.033
Mup19	major urinary protein 19	0.033
Dgat2	diacylglycerol O-acyltransferase 2	0.032
Prdx1	peroxiredoxin 1	0.032
Glyat	glycine-N-acyltransferase	0.032
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.032
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.031
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.031
Bphl	biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)	0.031
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.031
Vmn1r45	vomeronasal 1 receptor 45	0.031
Adamdec1	ADAM-like, decysin 1	0.030
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.030
Creg1	cellular repressor of E1A-stimulated genes 1	0.029
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.029
Angptl3	angiopoietin-like 3	0.029
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.028
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.028
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.028
Eps8l2	EPS8-like 2	0.026
Cyb5	cytochrome b-5	0.026
Tsku	tsukushin	0.026
Sval1	seminal vesicle antigen-like 1	0.026
Lyplal1	lysophospholipase-like 1	0.026
Mfsd7c	major facilitator superfamily domain containing 7C	0.026
Tpmt	thiopurine methyltransferase	0.025
Oxsm	3-oxoacyl-ACP synthase, mitochondrial	0.025
Akr1c13	aldo-keto reductase family 1, member C13	0.025
Ccbl2	cysteine conjugate-beta lyase 2	0.025
Ugt1a2	UDP glucuronosyltransferase 1 family, polypeptide A2	0.025
Cyp2c65	cytochrome P450, family 2, subfamily c, polypeptide 65	0.025
Abca6	ATP-binding cassette, sub-family A (ABC1), member 6	0.024
Pcx	pyruvate carboxylase	0.024
Cml5	camello-like 5	0.024
Zfyve21	zinc finger, FYVE domain containing 21	0.024
9130016M20Rik	RIKEN cDNA 9130016M20 gene	0.023
Pir	pirin	0.023
Khk	ketohexokinase	0.023
Tas2r105	taste receptor, type 2, member 105	0.023
Ephx2	epoxide hydrolase 2, cytoplasmic	0.023
Cyp2j6	cytochrome P450, family 2, subfamily j, polypeptide 6	0.023
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.023
Ropn1l	ropporin 1-like	0.023
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.023
Chchd10	coiled-coil-helix-coiled-coil-helix domain containing 10	0.023
Nrg4	neuregulin 4	0.023
Tmem30b	transmembrane protein 30B	0.022
Reep6	receptor accessory protein 6	0.022
Vnn1	vanin 1	0.022
Tmem141	transmembrane protein 141	0.022
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.021
Dsp	desmoplakin	0.021
Cyp3a59	cytochrome P450, subfamily 3A, polypeptide 59	0.021	Fly
Nicn1	nicolin 1	0.021
Slc15a1	solute carrier family 15 (oligopeptide transporter), member 1	0.021
Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	0.021
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.021
Rgn	regucalcin	0.020
Sult2a2	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2	0.020
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.020
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.020
Decr1	2,4-dienoyl CoA reductase 1, mitochondrial	0.020
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.020	Rat
Akr1e1	aldo-keto reductase family 1, member E1	0.019
Acy3	aspartoacylase (aminoacylase) 3	0.019
Cyp2a5	cytochrome P450, family 2, subfamily a, polypeptide 5	0.019
Btc	betacellulin, epidermal growth factor family member	0.019
Mt1	metallothionein 1	0.019
Psg28	pregnancy-specific glycoprotein 28	0.019
AF251705	cDNA sequence AF251705	0.018
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.018
2310030G06Rik	RIKEN cDNA 2310030G06 gene	0.018
Cpt2	carnitine palmitoyltransferase 2	0.018
Gss	glutathione synthetase	0.018
Apoc1	apolipoprotein C-I	0.018
Upp2	uridine phosphorylase 2	0.018
Akr1c14	aldo-keto reductase family 1, member C14	0.017
Thnsl2	threonine synthase-like 2 (bacterial)	0.017
Acot4	acyl-CoA thioesterase 4	0.017
Gm10639	predicted gene 10639	0.017	Rat
Dnase1l3	deoxyribonuclease 1-like 3	0.017
Hoga1	4-hydroxy-2-oxoglutarate aldolase 1	0.017
Prlr	prolactin receptor	0.016
AA522020	expressed sequence AA522020	0.016
Slc47a1	solute carrier family 47, member 1	0.016
Slc48a1	solute carrier family 48 (heme transporter), member 1	0.016
Cryl1	crystallin, lambda 1	0.016
Mup3	major urinary protein 3	0.016
Prl2c1	Prolactin family 2, subfamily c, member 1	0.016
Gsta1	glutathione S-transferase, alpha 1 (Ya)	0.016	Rat
Fetub	fetuin beta	0.016
Ocln	occludin	0.016
Hspb8	heat shock protein 8	0.016
Omd	osteomodulin	0.016
Akr1c19	aldo-keto reductase family 1, member C19	0.016
Iscu	IscU iron-sulfur cluster scaffold homolog (E. coli)	0.016
BC089597	cDNA sequence BC089597	0.016
Fam83h	family with sequence similarity 83, member H	0.016
Sqrdl	sulfide quinone reductase-like (yeast)	0.016
Ppl	periplakin	0.016
Pipox	pipecolic acid oxidase	0.015
Tmem53	transmembrane protein 53	0.015
Hamp	hepcidin antimicrobial peptide	0.015
Vmn1r51	vomeronasal 1 receptor 51	0.015
Cyp4a12b	cytochrome P450, family 4, subfamily a, polypeptide 12B	0.015
Tex12	testis expressed gene 12	0.015
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.015
Lrrc67	leucine rich repeat containing 67	0.015
Mttp	microsomal triglyceride transfer protein	0.015
Gpt	glutamic pyruvic transaminase, soluble	0.015
Prdx6	peroxiredoxin 6	0.015
Pxmp4	peroxisomal membrane protein 4	0.015
Rdh9	retinol dehydrogenase 9	0.015
Slc38a4	solute carrier family 38, member 4	0.015
Mocs1	molybdenum cofactor synthesis 1	0.015
Abhd4	abhydrolase domain containing 4	0.015
Pgm2	phosphoglucomutase 2	0.014
Mbl2	mannose-binding lectin (protein C) 2	0.014
Ugt1a6a	UDP glucuronosyltransferase 1 family, polypeptide A6A	0.014	Rat
Gstm7	glutathione S-transferase, mu 7	0.014	Human Mouse
Sult3a1	sulfotransferase family 3A, member 1	0.014
Cyp2d22	cytochrome P450, family 2, subfamily d, polypeptide 22	0.014
Fga	fibrinogen alpha chain	0.014
Dnase1l1	deoxyribonuclease 1-like 1	0.014
Zswim7	zinc finger, SWIM-type containing 7	0.014
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.014
Sec14l4	SEC14-like 4 (S. cerevisiae)	0.014
Pex11a	peroxisomal biogenesis factor 11 alpha	0.014
AA672641	expressed sequence AA672641	0.014
Ak3	adenylate kinase 3	0.014
Hacl1	2-hydroxyacyl-CoA lyase 1	0.014
Tm7sf3	transmembrane 7 superfamily member 3	0.014
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.014
AI317395	expressed sequence AI317395	0.013
1110032A03Rik	RIKEN cDNA 1110032A03 gene	0.013
Mcee	methylmalonyl CoA epimerase	0.013
Slc44a3	solute carrier family 44, member 3	0.013
0610007C21Rik	RIKEN cDNA 0610007C21 gene	0.013
Gas2	growth arrest specific 2	0.013
Mlxipl	MLX interacting protein-like	0.013
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.013
9030617O03Rik	RIKEN cDNA 9030617O03 gene	0.013
Glul	glutamate-ammonia ligase (glutamine synthetase)	0.013
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.013
Slc19a3	solute carrier family 19 (sodium/hydrogen exchanger), member 3	0.013
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.013
Spa17	sperm autoantigenic protein 17	0.013
Tlcd2	TLC domain containing 2	0.013
Pter	phosphotriesterase related	0.012
Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	0.012
Bhmt2	betaine-homocysteine methyltransferase 2	0.012
4931406C07Rik	RIKEN cDNA 4931406C07 gene	0.012
Asah2	N-acylsphingosine amidohydrolase 2	0.012
Cldn1	claudin 1	0.012
4930480G23Rik	RIKEN cDNA 4930480G23 gene	0.012
AB056442	cDNA sequence AB056442	0.012
Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	0.012
Dcxr	dicarbonyl L-xylulose reductase	0.012
Car14	carbonic anhydrase 14	0.012
Car13	carbonic anhydrase 13	0.012
Ppif	peptidylprolyl isomerase F (cyclophilin F)	0.012
Slc46a1	solute carrier family 46, member 1	0.012
Gm4788	predicted gene 4788	0.012
Gm15023	predicted gene 15023	0.012
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.012
Apoc2	apolipoprotein C-II	0.012
Ndrg2	N-myc downstream regulated gene 2	0.011
Ces1c	carboxylesterase 1C	0.011
Ptk6	PTK6 protein tyrosine kinase 6	0.011
Alas1	aminolevulinic acid synthase 1	0.011
Ang	angiogenin, ribonuclease, RNase A family, 5	0.011
Pgrmc1	progesterone receptor membrane component 1	0.011
Prdx2	peroxiredoxin 2	0.011
Upb1	ureidopropionase, beta	0.011
Fech	ferrochelatase	0.011
Ccdc152	coiled-coil domain containing 152	0.011
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.011
Mzt2	mitotic spindle organizing protein 2	0.011
Gpld1	glycosylphosphatidylinositol specific phospholipase D1	0.011
Tm6sf2	transmembrane 6 superfamily member 2	0.011
Mug1	murinoglobulin 1	0.011
Cth	cystathionase (cystathionine gamma-lyase)	0.011
Tcn2	transcobalamin 2	0.011
Neu2	neuraminidase 2	0.011
Orm1	orosomucoid 1	0.011
Olfr891	olfactory receptor 891	0.011
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.011
Stard5	StAR-related lipid transfer (START) domain containing 5	0.011
Adck3	aarF domain containing kinase 3	0.011
Magea5	melanoma antigen, family A, 5	0.010
Sucnr1	succinate receptor 1	0.010
Osbpl1a	oxysterol binding protein-like 1A	0.010
Aldh3b1	aldehyde dehydrogenase 3 family, member B1	0.010
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.010
Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7	0.010
H2-DMa	histocompatibility 2, class II, locus DMa	0.010
Mocos	molybdenum cofactor sulfurase	0.010
Acot1	acyl-CoA thioesterase 1	0.010
Orm3	orosomucoid 3	0.010
Decr2	2-4-dienoyl-Coenzyme A reductase 2, peroxisomal	0.010
BC026585	cDNA sequence BC026585	0.010
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.010