IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

natural killer cell proliferation

GO:0001787

The expansion of a natural killer cell population by cell division.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "natural killer cell proliferation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "natural killer cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
Foxp3	forkhead box P3	0.972
Irf9	interferon regulatory factor 9	0.951
Stat3	signal transducer and activator of transcription 3	0.927	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.786
Il6st	interleukin 6 signal transducer	0.708
Lepr	leptin receptor	0.494
Trim21	tripartite motif-containing 21	0.467
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.455
Jak2	Janus kinase 2	0.408
Prf1	perforin 1 (pore forming protein)	0.390
Il4ra	interleukin 4 receptor, alpha	0.376
Ehf	ets homologous factor	0.352	Mouse
Stat1	signal transducer and activator of transcription 1	0.335	Mouse
Il10	interleukin 10	0.311
Stat5b	signal transducer and activator of transcription 5B	0.290
Rab25	RAB25, member RAS oncogene family	0.262
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.258
Stat2	signal transducer and activator of transcription 2	0.255	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.238
Myd88	myeloid differentiation primary response gene 88	0.214
Esr2	estrogen receptor 2 (beta)	0.210
Ncoa3	nuclear receptor coactivator 3	0.210
Trp53	transformation related protein 53	0.195
Stat6	signal transducer and activator of transcription 6	0.184	Mouse
Irgm1	immunity-related GTPase family M member 1	0.164
Nckap1l	NCK associated protein 1 like	0.157
Elf3	E74-like factor 3	0.154	Mouse
Kit	kit oncogene	0.153
Esr1	estrogen receptor 1 (alpha)	0.143
Cldn4	claudin 4	0.141
Oit1	oncoprotein induced transcript 1	0.140
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.136
Arid1b	AT rich interactive domain 1B (SWI-like)	0.133
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.133
Il1r1	interleukin 1 receptor, type I	0.128
Smad3	MAD homolog 3 (Drosophila)	0.125
Tmprss2	transmembrane protease, serine 2	0.120
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.118
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.107
Ikzf1	IKAROS family zinc finger 1	0.104
Il15ra	interleukin 15 receptor, alpha chain	0.097
Parp14	poly (ADP-ribose) polymerase family, member 14	0.096
Muc1	mucin 1, transmembrane	0.090
Cldn7	claudin 7	0.089
Ccl2	chemokine (C-C motif) ligand 2	0.085
Tlr4	toll-like receptor 4	0.080
Irgm2	immunity-related GTPase family M member 2	0.079
Pparg	peroxisome proliferator activated receptor gamma	0.079
Nfil3	nuclear factor, interleukin 3, regulated	0.075
Il2	interleukin 2	0.074
Tnf	tumor necrosis factor	0.074
Ccr9	chemokine (C-C motif) receptor 9	0.073
Ptprc	protein tyrosine phosphatase, receptor type, C	0.073
Mlph	melanophilin	0.071
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.067
Cldn8	claudin 8	0.064
Lyz2	lysozyme 2	0.060
Cldn3	claudin 3	0.059
Pkp3	plakophilin 3	0.059
Ghr	growth hormone receptor	0.056
Apc	adenomatosis polyposis coli	0.056
Ar	androgen receptor	0.056
Il6	interleukin 6	0.054
Lep	leptin	0.054
Tspan1	tetraspanin 1	0.053
Ifnar2	interferon (alpha and beta) receptor 2	0.052
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.047
Socs1	suppressor of cytokine signaling 1	0.047
Spna1	spectrin alpha 1	0.045
Stat5a	signal transducer and activator of transcription 5A	0.044	Mouse
Cd247	CD247 antigen	0.044
Rel	reticuloendotheliosis oncogene	0.044
Ptgs2	prostaglandin-endoperoxide synthase 2	0.044
Cdcp1	CUB domain containing protein 1	0.043
Zfp36	zinc finger protein 36	0.043
Adar	adenosine deaminase, RNA-specific	0.041
Lck	lymphocyte protein tyrosine kinase	0.041
Prkcd	protein kinase C, delta	0.040
Il7r	interleukin 7 receptor	0.039
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.039
Il2rb	interleukin 2 receptor, beta chain	0.038
Jak1	Janus kinase 1	0.036
Parp12	poly (ADP-ribose) polymerase family, member 12	0.035
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.035
Traf3ip2	TRAF3 interacting protein 2	0.034
Cxcl17	chemokine (C-X-C motif) ligand 17	0.034
Il2rg	interleukin 2 receptor, gamma chain	0.034
Aff1	AF4/FMR2 family, member 1	0.033
Crb3	crumbs homolog 3 (Drosophila)	0.033
Marveld3	MARVEL (membrane-associating) domain containing 3	0.033
Igtp	interferon gamma induced GTPase	0.033
Sp100	nuclear antigen Sp100	0.031
Zfp185	zinc finger protein 185	0.029
Lgals9	lectin, galactose binding, soluble 9	0.029
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.028
Sykb	spleen tyrosine kinase	0.028
Fcgbp	Fc fragment of IgG binding protein	0.028
Il17re	interleukin 17 receptor E	0.028
Lrrc26	leucine rich repeat containing 26	0.028
Cd4	CD4 antigen	0.027
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.027
Irak4	interleukin-1 receptor-associated kinase 4	0.027
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.027
Rasgrp1	RAS guanyl releasing protein 1	0.027
Gbp7	guanylate binding protein 7	0.027
Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	0.026
Parp9	poly (ADP-ribose) polymerase family, member 9	0.026
Herc6	hect domain and RLD 6	0.026
Bach2	BTB and CNC homology 2	0.026
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.026
Tnk1	tyrosine kinase, non-receptor, 1	0.026
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.026
Trim30a	tripartite motif-containing 30A	0.026
Itgal	integrin alpha L	0.026
Gbp2	guanylate binding protein 2	0.025
Il17ra	interleukin 17 receptor A	0.025
Inpp5d	inositol polyphosphate-5-phosphatase D	0.024
Prss8	protease, serine, 8 (prostasin)	0.024
Cd96	CD96 antigen	0.024
Wfdc2	WAP four-disulfide core domain 2	0.024
Lgals8	lectin, galactose binding, soluble 8	0.024
Lat	linker for activation of T cells	0.023
Tapbp	TAP binding protein	0.023
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.023
Col4a3	collagen, type IV, alpha 3	0.023
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.022
Pdzk1ip1	PDZK1 interacting protein 1	0.022
Spint1	serine protease inhibitor, Kunitz type 1	0.022
Irf7	interferon regulatory factor 7	0.022
Ldlr	low density lipoprotein receptor	0.022
Cblc	Casitas B-lineage lymphoma c	0.021
Nmi	N-myc (and STAT) interactor	0.021
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.021
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.021
Prr15l	proline rich 15-like	0.021
Epcam	epithelial cell adhesion molecule	0.021
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.021
Tmem173	transmembrane protein 173	0.021
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.021
Epn3	epsin 3	0.021
Fam83g	family with sequence similarity 83, member G	0.020
Ildr1	immunoglobulin-like domain containing receptor 1	0.020
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.020
Irf1	interferon regulatory factor 1	0.020
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.020
Slc5a1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.020
Ahr	aryl-hydrocarbon receptor	0.020
Tacstd2	tumor-associated calcium signal transducer 2	0.020
Parp10	poly (ADP-ribose) polymerase family, member 10	0.020
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.019
Ppl	periplakin	0.019
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.019
Ifi203	interferon activated gene 203	0.019
Rab27a	RAB27A, member RAS oncogene family	0.019
Tmem71	transmembrane protein 71	0.019
Erap1	endoplasmic reticulum aminopeptidase 1	0.019
Acpp	acid phosphatase, prostate	0.019
Tnip1	TNFAIP3 interacting protein 1	0.018
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.018
Rasal3	RAS protein activator like 3	0.018
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.018
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.018
Rc3h1	RING CCCH (C3H) domains 1	0.018
Ep300	E1A binding protein p300	0.018
Itga4	integrin alpha 4	0.017
Casp7	caspase 7	0.017
Slurp1	secreted Ly6/Plaur domain containing 1	0.017
Wrn	Werner syndrome homolog (human)	0.017
Tor3a	torsin family 3, member A	0.017
Gbp3	guanylate binding protein 3	0.017
Ifi35	interferon-induced protein 35	0.016
Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	0.016
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.016
Pyhin1	pyrin and HIN domain family, member 1	0.016
Lyst	lysosomal trafficking regulator	0.016
Il4	interleukin 4	0.016
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.016
9130017N09Rik	RIKEN cDNA 9130017N09 gene	0.016
Krt13	keratin 13	0.016
Fam83h	family with sequence similarity 83, member H	0.015
Jak3	Janus kinase 3	0.015
Casp8	caspase 8	0.015
Zfp865	zinc finger protein 865	0.015
H2-K1	histocompatibility 2, K1, K region	0.015
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.015
BC006779	cDNA sequence BC006779	0.015
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.015
Mapk13	mitogen-activated protein kinase 13	0.015
Lalba	lactalbumin, alpha	0.015
Pomc	pro-opiomelanocortin-alpha	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.015
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.015
Ly96	lymphocyte antigen 96	0.015
Bcl2l14	BCL2-like 14 (apoptosis facilitator)	0.015
Cd3g	CD3 antigen, gamma polypeptide	0.015
Lad1	ladinin	0.015
Cd8a	CD8 antigen, alpha chain	0.014
Gabrp	gamma-aminobutyric acid (GABA) A receptor, pi	0.014
Card11	caspase recruitment domain family, member 11	0.014
Ltf	lactotransferrin	0.014
Uba7	ubiquitin-like modifier activating enzyme 7	0.014
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.014
Trim30d	tripartite motif-containing 30D	0.014
Tgtp2	T-cell specific GTPase 2	0.014
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.014
Tmprss4	transmembrane protease, serine 4	0.014
Trim26	tripartite motif-containing 26	0.014
Cytip	cytohesin 1 interacting protein	0.014
Gpx2	glutathione peroxidase 2	0.014
Sell	selectin, lymphocyte	0.014
S100a14	S100 calcium binding protein A14	0.014
Ifih1	interferon induced with helicase C domain 1	0.014
Cdk6	cyclin-dependent kinase 6	0.014
Cxcr2	chemokine (C-X-C motif) receptor 2	0.014
Cd28	CD28 antigen	0.014
Fut2	fucosyltransferase 2	0.014
Cyth1	cytohesin 1	0.014
Lair1	leukocyte-associated Ig-like receptor 1	0.013
Muc4	mucin 4	0.013
Pdcd6ip	programmed cell death 6 interacting protein	0.013
Batf	basic leucine zipper transcription factor, ATF-like	0.013
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.013
Il27ra	interleukin 27 receptor, alpha	0.013
Nfya	nuclear transcription factor-Y alpha	0.013
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.013
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.013
Lgals7	lectin, galactose binding, soluble 7	0.013
4933426M11Rik	RIKEN cDNA 4933426M11 gene	0.013
Insr	insulin receptor	0.013
Bglap2	bone gamma-carboxyglutamate protein 2	0.013
Psca	prostate stem cell antigen	0.013
Irf2	interferon regulatory factor 2	0.013
Txk	TXK tyrosine kinase	0.013
Samd9l	sterile alpha motif domain containing 9-like	0.013
Ttc7	tetratricopeptide repeat domain 7	0.013
Stom	stomatin	0.013
Tmprss13	transmembrane protease, serine 13	0.013
Fbp2	fructose bisphosphatase 2	0.012
Fasl	Fas ligand (TNF superfamily, member 6)	0.012
Iigp1	interferon inducible GTPase 1	0.012
Il12b	interleukin 12b	0.012
Sftpd	surfactant associated protein D	0.012
Irf2bp2	interferon regulatory factor 2 binding protein 2	0.012
Klf5	Kruppel-like factor 5	0.012
Ikbke	inhibitor of kappaB kinase epsilon	0.012
Zc3hav1	zinc finger CCCH type, antiviral 1	0.012
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.012
Foxn1	forkhead box N1	0.012
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	0.012
Scnn1b	sodium channel, nonvoltage-gated 1 beta	0.012
Cd3e	CD3 antigen, epsilon polypeptide	0.012
Psp	parotid secretory protein	0.012
Tgfb1	transforming growth factor, beta 1	0.012
Krtcap3	keratinocyte associated protein 3	0.012
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.012
Parp4	poly (ADP-ribose) polymerase family, member 4	0.012
Expi	extracellular proteinase inhibitor	0.012
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.012
Ly9	lymphocyte antigen 9	0.012
Slc44a3	solute carrier family 44, member 3	0.012
Rtp4	receptor transporter protein 4	0.012
Ankfy1	ankyrin repeat and FYVE domain containing 1	0.012
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.012
Fxyd3	FXYD domain-containing ion transport regulator 3	0.012
Slc44a4	solute carrier family 44, member 4	0.011
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.011
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.011
Il18rap	interleukin 18 receptor accessory protein	0.011
Gna13	guanine nucleotide binding protein, alpha 13	0.011
Il10rb	interleukin 10 receptor, beta	0.011
Hipk1	homeodomain interacting protein kinase 1	0.011
Arhgap8	Rho GTPase activating protein 8	0.011
Trim25	tripartite motif-containing 25	0.011
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.011
Sh2d2a	SH2 domain protein 2A	0.011
Traf1	TNF receptor-associated factor 1	0.011
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.011
Usp25	ubiquitin specific peptidase 25	0.011
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.011
Fam83f	family with sequence similarity 83, member F	0.011
Ifng	interferon gamma	0.011
Vav1	vav 1 oncogene	0.011
Gbp6	guanylate binding protein 6	0.011
Fgfbp1	fibroblast growth factor binding protein 1	0.011
Prr15	proline rich 15	0.011
Chad	chondroadherin	0.011
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.011
Cxcl15	chemokine (C-X-C motif) ligand 15	0.011
Mocs1	molybdenum cofactor synthesis 1	0.011
Lrrc23	leucine rich repeat containing 23	0.011
Agrp	agouti related protein	0.011
Samhd1	SAM domain and HD domain, 1	0.011
Arl10	ADP-ribosylation factor-like 10	0.011
Nup98	nucleoporin 98	0.010
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.010
Ifnar1	interferon (alpha and beta) receptor 1	0.010
Cd177	CD177 antigen	0.010
Ptprj	protein tyrosine phosphatase, receptor type, J	0.010
Chia	chitinase, acidic	0.010
Ticam1	toll-like receptor adaptor molecule 1	0.010
Ccr7	chemokine (C-C motif) receptor 7	0.010
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.010
Znfx1	zinc finger, NFX1-type containing 1	0.010
Tcfcp2l1	transcription factor CP2-like 1	0.010
Cd2	CD2 antigen	0.010
Kat5	K(lysine) acetyltransferase 5	0.010
Aim1	absent in melanoma 1	0.010
Foxa2	forkhead box A2	0.010
Slc5a8	solute carrier family 5 (iodide transporter), member 8	0.010