IMP: Integrative Multi-species Prediction

Mus musculus

10 genes annotated in mouse

Multi-species View

negative regulation of viral genome replication

GO:0045071

Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of viral genome replication"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of viral genome replication" (in gray)

Name	Description	Probability	Func Analog Organism
Irf7	interferon regulatory factor 7	1.000
Rsad2	radical S-adenosyl methionine domain containing 2	1.000
Usp18	ubiquitin specific peptidase 18	1.000
Isg15	ISG15 ubiquitin-like modifier	1.000	Human
Oas1a	2'-5' oligoadenylate synthetase 1A	0.998	Human
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.997
Rtp4	receptor transporter protein 4	0.996
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.995
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.977
Mx2	myxovirus (influenza virus) resistance 2	0.976
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.972	Human
Ifi44	interferon-induced protein 44	0.971
Oas2	2'-5' oligoadenylate synthetase 2	0.969
Zbp1	Z-DNA binding protein 1	0.963
Oas3	2'-5' oligoadenylate synthetase 3	0.904	Human
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.900	Human
Trim30a	tripartite motif-containing 30A	0.890
Mx1	myxovirus (influenza virus) resistance 1	0.866
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.865
Ifitm3	interferon induced transmembrane protein 3	0.849	Human
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.847
Irf9	interferon regulatory factor 9	0.813
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.801
Parp14	poly (ADP-ribose) polymerase family, member 14	0.772
Uba7	ubiquitin-like modifier activating enzyme 7	0.770
Slfn4	schlafen 4	0.726
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.691
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.676
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.628
Isg20	interferon-stimulated protein	0.512	Human
Tor3a	torsin family 3, member A	0.510
Trim30d	tripartite motif-containing 30D	0.483
Tmem106a	transmembrane protein 106A	0.442
BC006779	cDNA sequence BC006779	0.388
Stat2	signal transducer and activator of transcription 2	0.376
Oas1b	2'-5' oligoadenylate synthetase 1B	0.321
Ifih1	interferon induced with helicase C domain 1	0.315
Ly6a	lymphocyte antigen 6 complex, locus A	0.307
Irgm1	immunity-related GTPase family M member 1	0.289
Ifitm2	interferon induced transmembrane protein 2	0.252	Human
Lgals9	lectin, galactose binding, soluble 9	0.247
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.223
Cxcl10	chemokine (C-X-C motif) ligand 10	0.171
Neurod1	neurogenic differentiation 1	0.169
Mndal	myeloid nuclear differentiation antigen like	0.149
Saa3	serum amyloid A 3	0.145
Bst2	bone marrow stromal cell antigen 2	0.140
Parp12	poly (ADP-ribose) polymerase family, member 12	0.124
Ifi203	interferon activated gene 203	0.123
Plac8	placenta-specific 8	0.120
Lcn2	lipocalin 2	0.119
Gbp7	guanylate binding protein 7	0.115
Apol9a	apolipoprotein L 9a	0.112
Fcgr4	Fc receptor, IgG, low affinity IV	0.107
Traf3	TNF receptor-associated factor 3	0.105
Pyhin1	pyrin and HIN domain family, member 1	0.100
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.097
Herc6	hect domain and RLD 6	0.089
Il18bp	interleukin 18 binding protein	0.078
Epsti1	epithelial stromal interaction 1 (breast)	0.070
Hsph1	heat shock 105kDa/110kDa protein 1	0.070
Hnrnpc	heterogeneous nuclear ribonucleoprotein C	0.069
Xaf1	XIAP associated factor 1	0.067
Slfn2	schlafen 2	0.065
Slfn8	schlafen 8	0.064
Gch1	GTP cyclohydrolase 1	0.056
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.053
Igtp	interferon gamma induced GTPase	0.052
Hck	hemopoietic cell kinase	0.045
Ifitm1	interferon induced transmembrane protein 1	0.044
Ly6c2	lymphocyte antigen 6 complex, locus C2	0.042
H2-T24	histocompatibility 2, T region locus 24	0.042
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.041
Tmem176b	transmembrane protein 176B	0.036
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.036
Pml	promyelocytic leukemia	0.035
Ifi35	interferon-induced protein 35	0.035
Fcgr1	Fc receptor, IgG, high affinity I	0.033
Zc3hav1	zinc finger CCCH type, antiviral 1	0.033	Human
Parp9	poly (ADP-ribose) polymerase family, member 9	0.033
Gsdmd	gasdermin D	0.032
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.031	Mouse
Sp100	nuclear antigen Sp100	0.029
Sykb	spleen tyrosine kinase	0.029
Mlkl	mixed lineage kinase domain-like	0.029
Dtx3l	deltex 3-like (Drosophila)	0.029
Tmem176a	transmembrane protein 176A	0.028
Ltf	lactotransferrin	0.027
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.027
AI607873	expressed sequence AI607873	0.027
Znfx1	zinc finger, NFX1-type containing 1	0.027
Samhd1	SAM domain and HD domain, 1	0.026
Unc93b1	unc-93 homolog B1 (C. elegans)	0.025
Ifitm6	interferon induced transmembrane protein 6	0.024	Human
Cxcl9	chemokine (C-X-C motif) ligand 9	0.023
Samd9l	sterile alpha motif domain containing 9-like	0.022
Trim34a	tripartite motif-containing 34A	0.020
Irgm2	immunity-related GTPase family M member 2	0.018
Ly6e	lymphocyte antigen 6 complex, locus E	0.018
Ifi47	interferon gamma inducible protein 47	0.018
Pabpn1	poly(A) binding protein, nuclear 1	0.018
Txnip	thioredoxin interacting protein	0.018
Bst1	bone marrow stromal cell antigen 1	0.017
Clec1b	C-type lectin domain family 1, member b	0.017
Slfn5	schlafen 5	0.017
Mnda	myeloid cell nuclear differentiation antigen	0.016	Human
Parp10	poly (ADP-ribose) polymerase family, member 10	0.016	Human
Hdac2	histone deacetylase 2	0.015
Gm12185	predicted gene 12185	0.014
Parp1	poly (ADP-ribose) polymerase family, member 1	0.014
BC013712	cDNA sequence BC013712	0.014
Rbm14	RNA binding motif protein 14	0.014
Cdc7	cell division cycle 7 (S. cerevisiae)	0.014
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.014
Nlrc5	NLR family, CARD domain containing 5	0.013
l7Rn6	lethal, Chr 7, Rinchik 6	0.013
Myd88	myeloid differentiation primary response gene 88	0.013
Trim25	tripartite motif-containing 25	0.013
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.013
Clca1	chloride channel calcium activated 1	0.013
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.013
Ifi204	interferon activated gene 204	0.012	Human
Adar	adenosine deaminase, RNA-specific	0.012
Rnf31	ring finger protein 31	0.012
Ccndbp1	cyclin D-type binding-protein 1	0.012
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.012
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.011
Ezh1	enhancer of zeste homolog 1 (Drosophila)	0.011
Kpnb1	karyopherin (importin) beta 1	0.011
H2afy	H2A histone family, member Y	0.011
Sae1	SUMO1 activating enzyme subunit 1	0.011
Ccrl2	chemokine (C-C motif) receptor-like 2	0.011
Stat1	signal transducer and activator of transcription 1	0.011
Irg1	immunoresponsive gene 1	0.011
Klhl24	kelch-like 24 (Drosophila)	0.011
Gbp6	guanylate binding protein 6	0.011
Rbbp4	retinoblastoma binding protein 4	0.011
Ticam1	toll-like receptor adaptor molecule 1	0.011
Oas1c	2'-5' oligoadenylate synthetase 1C	0.010	Human
Camp	cathelicidin antimicrobial peptide	0.010
Mov10	Moloney leukemia virus 10	0.010
Frrs1	ferric-chelate reductase 1	0.010
Sf3b2	splicing factor 3b, subunit 2	0.010