IMP: Integrative Multi-species Prediction

Mus musculus

16 genes annotated in mouse

Multi-species View

nuclear transcribed mrna catabolic process

GO:0000956

The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nuclear transcribed mrna catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "nuclear transcribed mrna catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.921
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.743	Yeast
Rc3h1	RING CCCH (C3H) domains 1	0.614
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.424
Tnrc6b	trinucleotide repeat containing 6b	0.368
Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	0.291
Btg1	B-cell translocation gene 1, anti-proliferative	0.210
Neurl1a	neuralized homolog 1A (Drosophila)	0.201
Rbmxrt	RNA binding motif protein, X chromosome retrogene	0.136
Fos	FBJ osteosarcoma oncogene	0.133
Dusp1	dual specificity phosphatase 1	0.128
Junb	Jun-B oncogene	0.115
Hmgb1	high mobility group box 1	0.112
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.109
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.098
Kpnb1	karyopherin (importin) beta 1	0.094
Snrpa1	small nuclear ribonucleoprotein polypeptide A'	0.093
Srsf7	serine/arginine-rich splicing factor 7	0.087
Tmem123	transmembrane protein 123	0.084
Bptf	bromodomain PHD finger transcription factor	0.081
Srsf1	serine/arginine-rich splicing factor 1	0.080	Yeast
Wdr77	WD repeat domain 77	0.079
Prpf4b	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	0.075
Prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.072
Hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.065
Ddx17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.060	Yeast
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.060	Yeast
Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.055
Nono	non-POU-domain-containing, octamer binding protein	0.052
Ewsr1	Ewing sarcoma breakpoint region 1	0.052
Cnot6	CCR4-NOT transcription complex, subunit 6	0.048	Human Mouse Fly
Npm1	nucleophosmin 1	0.048
Trim32	tripartite motif-containing 32	0.047
Ccnl2	cyclin L2	0.042
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.040
Srsf2	serine/arginine-rich splicing factor 2	0.040
Cox4nb	COX4 neighbor	0.039
Bcl6	B-cell leukemia/lymphoma 6	0.038
Srsf6	serine/arginine-rich splicing factor 6	0.038
Rpl7l1	ribosomal protein L7-like 1	0.037
Brd4	bromodomain containing 4	0.037
Atf3	activating transcription factor 3	0.036
0610009D07Rik	RIKEN cDNA 0610009D07 gene	0.036
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.036
Phf5a	PHD finger protein 5A	0.036
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.036
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.034
Ubp1	upstream binding protein 1	0.034
Actl6a	actin-like 6A	0.031
Rbm7	RNA binding motif protein 7	0.031
Nr2c2	nuclear receptor subfamily 2, group C, member 2	0.031
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.030
Anp32b	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.030
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.030
Rfx7	regulatory factor X, 7	0.029
Cd28	CD28 antigen	0.029
Egr1	early growth response 1	0.028
Snrnp40	small nuclear ribonucleoprotein 40 (U5)	0.028
2310036O22Rik	RIKEN cDNA 2310036O22 gene	0.028
Emg1	EMG1 nucleolar protein homolog (S. cerevisiae)	0.027
Fbxo11	F-box protein 11	0.027
Jun	Jun oncogene	0.027
Ncbp1	nuclear cap binding protein subunit 1	0.027
Polr2h	polymerase (RNA) II (DNA directed) polypeptide H	0.026
Tia1	cytotoxic granule-associated RNA binding protein 1	0.026	Yeast
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.026
Thoc4	THO complex 4	0.026
U2af1	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1	0.025
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.025
2810403A07Rik	RIKEN cDNA 2810403A07 gene	0.024
Brd2	bromodomain containing 2	0.024
H3f3a	H3 histone, family 3A	0.024
Rpl22	ribosomal protein L22	0.024
Ier2	immediate early response 2	0.023
Erbb2ip	Erbb2 interacting protein	0.023
Ncoa1	nuclear receptor coactivator 1	0.023
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.023
Akt2	thymoma viral proto-oncogene 2	0.023	Yeast
Ldb3	LIM domain binding 3	0.023
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.023
Pabpc1	poly(A) binding protein, cytoplasmic 1	0.023
Tnrc6a	trinucleotide repeat containing 6a	0.023
Rpa3	replication protein A3	0.023
Nipbl	Nipped-B homolog (Drosophila)	0.022
Chfr	checkpoint with forkhead and ring finger domains	0.022
Tex10	testis expressed gene 10	0.021
Ptma	prothymosin alpha	0.021
Hmgn1	high mobility group nucleosomal binding domain 1	0.021
Zc3h11a	zinc finger CCCH type containing 11A	0.021
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.021
Kdm3a	lysine (K)-specific demethylase 3A	0.021
Mbtd1	mbt domain containing 1	0.021
Ssbp1	single-stranded DNA binding protein 1	0.020
Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.020
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.020
Dtymk	deoxythymidylate kinase	0.020
Tfdp1	transcription factor Dp 1	0.020
Akt1	thymoma viral proto-oncogene 1	0.020	Yeast
Mcl1	myeloid cell leukemia sequence 1	0.019
Tbca	tubulin cofactor A	0.019
Ube2n	ubiquitin-conjugating enzyme E2N	0.018
Erh	enhancer of rudimentary homolog (Drosophila)	0.018
Nap1l1	nucleosome assembly protein 1-like 1	0.018
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.018
Ddx21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.018
Ttc13	tetratricopeptide repeat domain 13	0.018
Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein	0.017
Zfp329	zinc finger protein 329	0.017
Xpot	exportin, tRNA (nuclear export receptor for tRNAs)	0.017
Vhl	von Hippel-Lindau tumor suppressor	0.017
Rnf145	ring finger protein 145	0.017
Wnk1	WNK lysine deficient protein kinase 1	0.016
Snrpb2	U2 small nuclear ribonucleoprotein B	0.016
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.016
Zmynd11	zinc finger, MYND domain containing 11	0.016
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.016	Yeast
Dcaf13	DDB1 and CUL4 associated factor 13	0.016
Polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.016
Snrpe	small nuclear ribonucleoprotein E	0.015
Rasal3	RAS protein activator like 3	0.015
Zmym5	zinc finger, MYM-type 5	0.015
Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.015
Topbp1	topoisomerase (DNA) II binding protein 1	0.015
Nsun2	NOL1/NOP2/Sun domain family member 2	0.015
Pabpn1	poly(A) binding protein, nuclear 1	0.015
Lig4	ligase IV, DNA, ATP-dependent	0.015
Fbl	fibrillarin	0.015
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.015
Ilf2	interleukin enhancer binding factor 2	0.015
Luc7l3	LUC7-like 3 (S. cerevisiae)	0.015
Naa38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.015
Pdcd4	programmed cell death 4	0.015
Igf1r	insulin-like growth factor I receptor	0.014
Nlk	nemo like kinase	0.014
Ankhd1	ankyrin repeat and KH domain containing 1	0.014
Rbm10	RNA binding motif protein 10	0.014
Rasal1	RAS protein activator like 1 (GAP1 like)	0.014
B230308N11Rik	RIKEN cDNA B230308N11 gene	0.014
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.014
5830433M19Rik	RIKEN cDNA 5830433M19 gene	0.014
Upf3b	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.014
D10Wsu102e	DNA segment, Chr 10, Wayne State University 102, expressed	0.014
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.014
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.014
2810046L04Rik	RIKEN cDNA 2810046L04 gene	0.014
Rc3h2	ring finger and CCCH-type zinc finger domains 2	0.014	Mouse
Foxo1	forkhead box O1	0.014
Ttc27	tetratricopeptide repeat domain 27	0.014
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.014
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.013
Rbm14	RNA binding motif protein 14	0.013
Gsk3b	glycogen synthase kinase 3 beta	0.013
Thoc3	THO complex 3	0.013
Zfp148	zinc finger protein 148	0.013
Nup153	nucleoporin 153	0.013
Pim1	proviral integration site 1	0.013
Mael	maelstrom homolog (Drosophila)	0.013
Smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.013
Usp10	ubiquitin specific peptidase 10	0.013
Rdbp	RD RNA-binding protein	0.013
Jmjd1c	jumonji domain containing 1C	0.013
Ngdn	neuroguidin, EIF4E binding protein	0.013
Polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.013
Utp18	UTP18, small subunit (SSU) processome component, homolog (yeast)	0.013
Zfc3h1	zinc finger, C3H1-type containing	0.013
Ttc3	tetratricopeptide repeat domain 3	0.013
Celf1	CUGBP, Elav-like family member 1	0.012
Hgs	HGF-regulated tyrosine kinase substrate	0.012
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.012
Rps20	ribosomal protein S20	0.012
Ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.012
Nupl1	nucleoporin like 1	0.012
Pcna	proliferating cell nuclear antigen	0.012
Ppan	peter pan homolog (Drosophila)	0.012
Nmd3	NMD3 homolog (S. cerevisiae)	0.012
Rcor1	REST corepressor 1	0.012
Rcc2	regulator of chromosome condensation 2	0.012
Ranbp1	RAN binding protein 1	0.012
Rsl24d1	ribosomal L24 domain containing 1	0.012
Hnrnpul1	heterogeneous nuclear ribonucleoprotein U-like 1	0.011
Ammecr1l	AMME chromosomal region gene 1-like	0.011
Mapkap1	mitogen-activated protein kinase associated protein 1	0.011
Cetn2	centrin 2	0.011
Morc2a	microrchidia 2A	0.011
Zbtb1	zinc finger and BTB domain containing 1	0.011
Clns1a	chloride channel, nucleotide-sensitive, 1A	0.011
Med13	mediator complex subunit 13	0.011
Mcmbp	MCM (minichromosome maintenance deficient) binding protein	0.011
Elf1	E74-like factor 1	0.011
Dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	0.011
Rnpc3	RNA-binding region (RNP1, RRM) containing 3	0.011
Tcf12	transcription factor 12	0.011
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.011
Tdg	thymine DNA glycosylase	0.011
Zfp26	zinc finger protein 26	0.011
Igh	immunoglobulin heavy chain complex	0.011
Nhp2	NHP2 ribonucleoprotein homolog (yeast)	0.011
Ythdc1	YTH domain containing 1	0.011
Pbx2	pre B-cell leukemia transcription factor 2	0.010
Lrrc40	leucine rich repeat containing 40	0.010
Snrpd1	small nuclear ribonucleoprotein D1	0.010
Caprin1	cell cycle associated protein 1	0.010
Rhob	ras homolog gene family, member B	0.010
Nup188	nucleoporin 188	0.010
Midn	midnolin	0.010
Stk4	serine/threonine kinase 4	0.010
Edc4	enhancer of mRNA decapping 4	0.010
Blnk	B-cell linker	0.010
Exosc7	exosome component 7	0.010
Srsf3	serine/arginine-rich splicing factor 3	0.010
Klf6	Kruppel-like factor 6	0.010
Cramp1l	Crm, cramped-like (Drosophila)	0.010