IMP
Process View
negative regulation of mitosis
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mitosis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Shh | sonic hedgehog | 0.905 | ||
| Trp53 | transformation related protein 53 | 0.902 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.695 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.580 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.309 | ||
| Ccne1 | cyclin E1 | 0.307 | Fly | |
| Ccnb1 | cyclin B1 | 0.282 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.252 | Yeast | |
| C330027C09Rik | RIKEN cDNA C330027C09 gene | 0.230 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.228 | ||
| Cdk1 | cyclin-dependent kinase 1 | 0.215 | ||
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.193 | Yeast | |
| Kif23 | kinesin family member 23 | 0.172 | ||
| Ccnf | cyclin F | 0.158 | ||
| Sox9 | SRY-box containing gene 9 | 0.140 | ||
| Kif2c | kinesin family member 2C | 0.127 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.124 | ||
| Spag5 | sperm associated antigen 5 | 0.118 | ||
| Pten | phosphatase and tensin homolog | 0.104 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.100 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.095 | ||
| Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.090 | ||
| Kif20a | kinesin family member 20A | 0.082 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.081 | ||
| Foxc1 | forkhead box C1 | 0.073 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.071 | Fly | |
| Brca1 | breast cancer 1 | 0.070 | ||
| Ccna2 | cyclin A2 | 0.069 | ||
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.067 | ||
| Pds5b | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.065 | ||
| Blm | Bloom syndrome, RecQ helicase-like | 0.060 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.059 | Human | |
| Neurog2 | neurogenin 2 | 0.059 | ||
| Ooep | oocyte expressed protein homolog (dog) | 0.056 | ||
| Melk | maternal embryonic leucine zipper kinase | 0.056 | ||
| Kif4 | kinesin family member 4 | 0.055 | ||
| Rpgrip1l | Rpgrip1-like | 0.053 | ||
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.051 | ||
| Ptch1 | patched homolog 1 | 0.048 | ||
| Cenpk | centromere protein K | 0.047 | ||
| Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.046 | ||
| Cdca8 | cell division cycle associated 8 | 0.045 | ||
| Ccnb2 | cyclin B2 | 0.045 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.045 | ||
| Dtl | denticleless homolog (Drosophila) | 0.044 | ||
| Birc5 | baculoviral IAP repeat-containing 5 | 0.041 | ||
| Kif11 | kinesin family member 11 | 0.040 | ||
| Aurka | aurora kinase A | 0.039 | ||
| Skp1a | S-phase kinase-associated protein 1A | 0.039 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.039 | ||
| Gsg2 | germ cell-specific gene 2 | 0.038 | ||
| 4632434I11Rik | RIKEN cDNA 4632434I11 gene | 0.036 | ||
| Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.034 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.034 | ||
| Pthlh | parathyroid hormone-like peptide | 0.034 | ||
| Kif22 | kinesin family member 22 | 0.033 | ||
| Gtse1 | G two S phase expressed protein 1 | 0.033 | ||
| Nf1 | neurofibromatosis 1 | 0.033 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.032 | Human | |
| Sgol1 | shugoshin-like 1 (S. pombe) | 0.032 | ||
| Sgol2 | shugoshin-like 2 (S. pombe) | 0.031 | ||
| Suv39h2 | suppressor of variegation 3-9 homolog 2 (Drosophila) | 0.029 | ||
| 2610039C10Rik | RIKEN cDNA 2610039C10 gene | 0.029 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.029 | ||
| Dna2 | DNA replication helicase 2 homolog (yeast) | 0.027 | ||
| Mis18bp1 | MIS18 binding protein 1 | 0.027 | ||
| Trp63 | transformation related protein 63 | 0.026 | ||
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.026 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.024 | ||
| Cenpn | centromere protein N | 0.024 | ||
| Ywhae | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.024 | Yeast | |
| Msx1 | homeobox, msh-like 1 | 0.024 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.023 | ||
| Mns1 | meiosis-specific nuclear structural protein 1 | 0.022 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.022 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.022 | ||
| Cdc45 | cell division cycle 45 homolog (S. cerevisiae) | 0.020 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.019 | ||
| Plk4 | polo-like kinase 4 (Drosophila) | 0.019 | ||
| Anln | anillin, actin binding protein | 0.019 | ||
| Chaf1b | chromatin assembly factor 1, subunit B (p60) | 0.019 | ||
| Cenpe | centromere protein E | 0.018 | ||
| Rb1 | retinoblastoma 1 | 0.018 | ||
| Ccdc99 | coiled-coil domain containing 99 | 0.018 | ||
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.018 | ||
| Trim59 | tripartite motif-containing 59 | 0.018 | ||
| Aurkb | aurora kinase B | 0.017 | ||
| Ywhah | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.017 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.017 | ||
| Brca2 | breast cancer 2 | 0.016 | ||
| Hist1h2bm | histone cluster 1, H2bm | 0.016 | ||
| Stil | Scl/Tal1 interrupting locus | 0.015 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.015 | ||
| Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.015 | Yeast | |
| Ckap2 | cytoskeleton associated protein 2 | 0.015 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.015 | ||
| Aspm | asp (abnormal spindle)-like, microcephaly associated (Drosophila) | 0.015 | ||
| Orc1 | origin recognition complex, subunit 1 | 0.015 | ||
| Lmnb1 | lamin B1 | 0.015 | ||
| 6720463M24Rik | RIKEN cDNA 6720463M24 gene | 0.014 | ||
| E2f8 | E2F transcription factor 8 | 0.014 | ||
| Cbx1 | chromobox homolog 1 (Drosophila HP1 beta) | 0.014 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.014 | ||
| Lin9 | lin-9 homolog (C. elegans) | 0.014 | ||
| Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.013 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.013 | ||
| Nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.013 | ||
| Ndc80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.013 | ||
| Hells | helicase, lymphoid specific | 0.013 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.013 | ||
| Igh | immunoglobulin heavy chain complex | 0.012 | ||
| Dsn1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.012 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.012 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.012 | Human | |
| Ncapg | non-SMC condensin I complex, subunit G | 0.012 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.012 | ||
| Mxd3 | Max dimerization protein 3 | 0.012 | ||
| Recql | RecQ protein-like | 0.011 | ||
| Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.011 | Human | |
| Eed | embryonic ectoderm development | 0.011 | ||
| Cdca4 | cell division cycle associated 4 | 0.011 | ||
| Lig4 | ligase IV, DNA, ATP-dependent | 0.011 | ||
| H2afz | H2A histone family, member Z | 0.011 | ||
| Ncapd3 | non-SMC condensin II complex, subunit D3 | 0.011 | ||
| Nedd4l | neural precursor cell expressed, developmentally down-regulated gene 4-like | 0.010 | ||
| 2810417H13Rik | RIKEN cDNA 2810417H13 gene | 0.010 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.010 | ||
| Ppih | peptidyl prolyl isomerase H | 0.010 | ||
| Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.010 | ||
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.010 | ||
| Orc2 | origin recognition complex, subunit 2 | 0.010 |