IMP: Integrative Multi-species Prediction

Mus musculus

56 genes annotated in mouse

response to reactive oxygen species

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouseInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to reactive oxygen species"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to reactive oxygen species" (in gray)

Name	Description	Probability	Func Analog Organism
Mapk14	mitogen-activated protein kinase 14	0.988	Mouse Worm Fly
Trp53	transformation related protein 53	0.972
Rnf2	ring finger protein 2	0.853
Clock	circadian locomotor output cycles kaput	0.849
Pten	phosphatase and tensin homolog	0.847
Dusp1	dual specificity phosphatase 1	0.799
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.744
Rybp	RING1 and YY1 binding protein	0.743
Lox	lysyl oxidase	0.739
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.712
Apoe	apolipoprotein E	0.688
Hbb-b1	hemoglobin, beta adult major chain	0.685
Cry2	cryptochrome 2 (photolyase-like)	0.620
Per2	period homolog 2 (Drosophila)	0.601	Zebrafish
Mapkapk2	MAP kinase-activated protein kinase 2	0.570
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.529
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.518
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.505	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.491
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.435
Plxnd1	plexin D1	0.433
Thbs1	thrombospondin 1	0.419
Ltbp2	latent transforming growth factor beta binding protein 2	0.416	Mouse
Pxn	paxillin	0.380	Human
Nos1	nitric oxide synthase 1, neuronal	0.379	Rat
Btg2	B-cell translocation gene 2, anti-proliferative	0.371
Fbn1	fibrillin 1	0.367
Prkce	protein kinase C, epsilon	0.353
Cav1	caveolin 1, caveolae protein	0.295
Stat3	signal transducer and activator of transcription 3	0.292
Mitf	microphthalmia-associated transcription factor	0.282
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.281
Cyld	cylindromatosis (turban tumor syndrome)	0.278
Kpna1	karyopherin (importin) alpha 1	0.277
Vegfa	vascular endothelial growth factor A	0.275
Phc2	polyhomeotic-like 2 (Drosophila)	0.271
Blnk	B-cell linker	0.271
Mdm2	transformed mouse 3T3 cell double minute 2	0.270
Rarg	retinoic acid receptor, gamma	0.260
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.258
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.255
Prnp	prion protein	0.252
Atf2	activating transcription factor 2	0.249
Ghr	growth hormone receptor	0.235
Pparg	peroxisome proliferator activated receptor gamma	0.234
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.215
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.214
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.211
Ptgs2	prostaglandin-endoperoxide synthase 2	0.209
Cry1	cryptochrome 1 (photolyase-like)	0.208	Zebrafish
Prdx1	peroxiredoxin 1	0.208
Ep300	E1A binding protein p300	0.205
Gab1	growth factor receptor bound protein 2-associated protein 1	0.204
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.196
Cd40	CD40 antigen	0.196
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.193
Sqstm1	sequestosome 1	0.187
Per1	period homolog 1 (Drosophila)	0.184
Ccbp2	chemokine binding protein 2	0.184
Mdm4	transformed mouse 3T3 cell double minute 4	0.178
Myd88	myeloid differentiation primary response gene 88	0.178
Junb	Jun-B oncogene	0.175
Src	Rous sarcoma oncogene	0.172	Rat
Cbx7	chromobox homolog 7	0.167
Cyr61	cysteine rich protein 61	0.166
Agtr2	angiotensin II receptor, type 2	0.159
Ager	advanced glycosylation end product-specific receptor	0.156	Rat
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.154
Htra3	HtrA serine peptidase 3	0.152
Eed	embryonic ectoderm development	0.148
Kit	kit oncogene	0.146
Lrp2	low density lipoprotein receptor-related protein 2	0.143
Fgfr1	fibroblast growth factor receptor 1	0.142
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.141
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.139
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.138
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.138
Mapk1	mitogen-activated protein kinase 1	0.138	Fly
Bag3	BCL2-associated athanogene 3	0.134
Idua	iduronidase, alpha-L-	0.131
Stk38	serine/threonine kinase 38	0.130
Pcgf2	polycomb group ring finger 2	0.130
Sftpd	surfactant associated protein D	0.127
Epas1	endothelial PAS domain protein 1	0.127
Stim2	stromal interaction molecule 2	0.127
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.126
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.126
Akt1	thymoma viral proto-oncogene 1	0.123
Myc	myelocytomatosis oncogene	0.119
Lrpprc	leucine-rich PPR-motif containing	0.118
Plcg1	phospholipase C, gamma 1	0.118	Rat
Ctnnb1	catenin (cadherin associated protein), beta 1	0.118
Jarid2	jumonji, AT rich interactive domain 2	0.117
Igh	immunoglobulin heavy chain complex	0.116
E2f1	E2F transcription factor 1	0.110
Lrp1	low density lipoprotein receptor-related protein 1	0.109
Tlr4	toll-like receptor 4	0.109
Cryab	crystallin, alpha B	0.108
Gdnf	glial cell line derived neurotrophic factor	0.106
Kitl	kit ligand	0.106
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.106
Prkcc	protein kinase C, gamma	0.103
Insr	insulin receptor	0.102	Worm
Grb2	growth factor receptor bound protein 2	0.102
Pea15a	phosphoprotein enriched in astrocytes 15A	0.102
Nos3	nitric oxide synthase 3, endothelial cell	0.102
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.100
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.100
Lep	leptin	0.100
Mmp9	matrix metallopeptidase 9	0.099
Thbs2	thrombospondin 2	0.097	Mouse
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.094
Dnm1l	dynamin 1-like	0.093
Thrb	thyroid hormone receptor beta	0.092
Bak1	BCL2-antagonist/killer 1	0.092	Mouse
Ldlr	low density lipoprotein receptor	0.091
Ring1	ring finger protein 1	0.091
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.090
Spp1	secreted phosphoprotein 1	0.090
Pvr	poliovirus receptor	0.090
Prrx2	paired related homeobox 2	0.089
Tgfb2	transforming growth factor, beta 2	0.088
Nampt	nicotinamide phosphoribosyltransferase	0.087
Vhl	von Hippel-Lindau tumor suppressor	0.087
Ptk2	PTK2 protein tyrosine kinase 2	0.086
Klf4	Kruppel-like factor 4 (gut)	0.085
Tcra	T-cell receptor alpha chain	0.085
Per3	period homolog 3 (Drosophila)	0.084
Mfn2	mitofusin 2	0.084
Cks2	CDC28 protein kinase regulatory subunit 2	0.083
Mapk8	mitogen-activated protein kinase 8	0.082
Pkd1	polycystic kidney disease 1 homolog	0.082
Bicc1	bicaudal C homolog 1 (Drosophila)	0.082
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.081
Mt1	metallothionein 1	0.080
Fbln5	fibulin 5	0.078
Gata3	GATA binding protein 3	0.078
Gsn	gelsolin	0.078
Il6st	interleukin 6 signal transducer	0.077
Cd44	CD44 antigen	0.076
Traf2	TNF receptor-associated factor 2	0.076
Tcrb	T-cell receptor beta chain	0.075
Rara	retinoic acid receptor, alpha	0.075
Msln	mesothelin	0.074
Ngf	nerve growth factor	0.074
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.073
Hoxa1	homeobox A1	0.073
Dnm1	dynamin 1	0.072
Duox2	dual oxidase 2	0.072
Chia	chitinase, acidic	0.071
Wwox	WW domain-containing oxidoreductase	0.071
Gstm1	glutathione S-transferase, mu 1	0.070
Tgfbr1	transforming growth factor, beta receptor I	0.070
Adra2b	adrenergic receptor, alpha 2b	0.070
Timp3	tissue inhibitor of metalloproteinase 3	0.070
Ate1	arginyltransferase 1	0.070
Grb10	growth factor receptor bound protein 10	0.070
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.069
Npc1	Niemann Pick type C1	0.068
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.067
Pax8	paired box gene 8	0.067	Mouse
Aebp1	AE binding protein 1	0.067
Dok1	docking protein 1	0.067
Atf3	activating transcription factor 3	0.066
Nrap	nebulin-related anchoring protein	0.066
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.066
Tgfb1	transforming growth factor, beta 1	0.066
Dlg1	discs, large homolog 1 (Drosophila)	0.066
Rac1	RAS-related C3 botulinum substrate 1	0.066
Sgpl1	sphingosine phosphate lyase 1	0.065
Gspt1	G1 to S phase transition 1	0.065
Pgls	6-phosphogluconolactonase	0.065
Csnk1e	casein kinase 1, epsilon	0.063
Eln	elastin	0.063
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.062	Mouse
Mybpc3	myosin binding protein C, cardiac	0.062
Hint1	histidine triad nucleotide binding protein 1	0.062
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.061	Rat
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.061
Actn2	actinin alpha 2	0.061
Mapk3	mitogen-activated protein kinase 3	0.060	Fly
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.060
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.059	Rat
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.059
Lama4	laminin, alpha 4	0.058
Cd8a	CD8 antigen, alpha chain	0.058
Sulf2	sulfatase 2	0.058
Hspb1	heat shock protein 1	0.058	Mouse
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.058
Gna13	guanine nucleotide binding protein, alpha 13	0.058
Cd40lg	CD40 ligand	0.057
Flt1	FMS-like tyrosine kinase 1	0.057
Egr1	early growth response 1	0.056
Cd4	CD4 antigen	0.056
Rgs9	regulator of G-protein signaling 9	0.056
Smyd1	SET and MYND domain containing 1	0.056
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.056
Ece1	endothelin converting enzyme 1	0.055
Mt2	metallothionein 2	0.055
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.055
Prrx1	paired related homeobox 1	0.055
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.055
Has1	hyaluronan synthase1	0.055
Kat2a	K(lysine) acetyltransferase 2A	0.054
Sik3	SIK family kinase 3	0.054
Bcl6	B-cell leukemia/lymphoma 6	0.054
Arrb1	arrestin, beta 1	0.054
Fth1	ferritin heavy chain 1	0.054
Aebp2	AE binding protein 2	0.054
Capn1	calpain 1	0.054
Bmp5	bone morphogenetic protein 5	0.054
Sfrp4	secreted frizzled-related protein 4	0.053
Runx2	runt related transcription factor 2	0.053
Sphk1	sphingosine kinase 1	0.053	Rat
Krt15	keratin 15	0.053
Itgav	integrin alpha V	0.053
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.053
Mup4	major urinary protein 4	0.052
Phc1	polyhomeotic-like 1 (Drosophila)	0.052
Sftpc	surfactant associated protein C	0.052
Prlr	prolactin receptor	0.051
Birc3	baculoviral IAP repeat-containing 3	0.051
Mavs	mitochondrial antiviral signaling protein	0.051
Igfbp6	insulin-like growth factor binding protein 6	0.050
Tgfb3	transforming growth factor, beta 3	0.050
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.050
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.050
Steap3	STEAP family member 3	0.050
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.050
Cfh	complement component factor h	0.049
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.049
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.049
Lcn3	lipocalin 3	0.049
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.049
Hif1a	hypoxia inducible factor 1, alpha subunit	0.049	Rat
Hnf1b	HNF1 homeobox B	0.048
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.048
Itch	itchy, E3 ubiquitin protein ligase	0.048
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.048
Huwe1	HECT, UBA and WWE domain containing 1	0.048
F3	coagulation factor III	0.048
Phldb1	pleckstrin homology-like domain, family B, member 1	0.048
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.048
Ikzf3	IKAROS family zinc finger 3	0.048
Ptgfr	prostaglandin F receptor	0.047
Sulf1	sulfatase 1	0.047
Fgfr3	fibroblast growth factor receptor 3	0.047
Cyb5	cytochrome b-5	0.047
Foxo3	forkhead box O3	0.047	Mouse
Phf1	PHD finger protein 1	0.047
Ftl1	ferritin light chain 1	0.046
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.046
Tmem123	transmembrane protein 123	0.046
Pitx3	paired-like homeodomain transcription factor 3	0.045
Vcl	vinculin	0.045
Plat	plasminogen activator, tissue	0.045
Tenc1	tensin like C1 domain-containing phosphatase	0.045
Ifngr1	interferon gamma receptor 1	0.045
Fgfr2	fibroblast growth factor receptor 2	0.045
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.045
Scp2	sterol carrier protein 2, liver	0.045
Acvr1	activin A receptor, type 1	0.044
Osmr	oncostatin M receptor	0.044
Ccnb2	cyclin B2	0.044
Bax	BCL2-associated X protein	0.044	Mouse
Klc1	kinesin light chain 1	0.044
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.044
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.043
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.043
Fxr2	fragile X mental retardation, autosomal homolog 2	0.043
Cd19	CD19 antigen	0.043
Bcl2l1	BCL2-like 1	0.043	Mouse
Mkl2	MKL/myocardin-like 2	0.043
Msh2	mutS homolog 2 (E. coli)	0.042
Pbk	PDZ binding kinase	0.042
Cul4a	cullin 4A	0.042
Lepr	leptin receptor	0.042
Notch2	Notch gene homolog 2 (Drosophila)	0.041
Gpx1	glutathione peroxidase 1	0.041
Anln	anillin, actin binding protein	0.041
Pygo2	pygopus 2	0.041
Pfkl	phosphofructokinase, liver, B-type	0.041
Fmo3	flavin containing monooxygenase 3	0.041
Pmm1	phosphomannomutase 1	0.041
Mapk11	mitogen-activated protein kinase 11	0.041	Mouse Worm Fly
Slc31a1	solute carrier family 31, member 1	0.041
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.041
Ch25h	cholesterol 25-hydroxylase	0.040
Rexo2	REX2, RNA exonuclease 2 homolog (S. cerevisiae)	0.040
Plaa	phospholipase A2, activating protein	0.040
C9	complement component 9	0.040
Apob	apolipoprotein B	0.040
Cfd	complement factor D (adipsin)	0.040
Bmper	BMP-binding endothelial regulator	0.040
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.040
Foxo1	forkhead box O1	0.040
Htra1	HtrA serine peptidase 1	0.040
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.040
Gmnn	geminin	0.040
Mag	myelin-associated glycoprotein	0.039
Rps3	ribosomal protein S3	0.039
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.039
Il1r1	interleukin 1 receptor, type I	0.039	Rat
Bcl2	B-cell leukemia/lymphoma 2	0.039
Ptpre	protein tyrosine phosphatase, receptor type, E	0.039
Mapk9	mitogen-activated protein kinase 9	0.039	Mouse Fly
S1pr2	sphingosine-1-phosphate receptor 2	0.039
Cd28	CD28 antigen	0.039
Rb1	retinoblastoma 1	0.038
Tnf	tumor necrosis factor	0.038
Wdfy2	WD repeat and FYVE domain containing 2	0.038
Atf4	activating transcription factor 4	0.038
Thbd	thrombomodulin	0.038
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.038
Slc12a6	solute carrier family 12, member 6	0.038
Apod	apolipoprotein D	0.038
Ces1g	carboxylesterase 1G	0.038
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.037
Gm3776	predicted gene 3776	0.037
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.037
Nsf	N-ethylmaleimide sensitive fusion protein	0.037
Ctsd	cathepsin D	0.037
Vcp	valosin containing protein	0.037
Mta1	metastasis associated 1	0.036
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.036
Sykb	spleen tyrosine kinase	0.036
Tal1	T-cell acute lymphocytic leukemia 1	0.036
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.036
Fam164c	family with sequence similarity 164, member C	0.036
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.036
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.036
Col8a1	collagen, type VIII, alpha 1	0.036
Lmna	lamin A	0.036
Epha2	Eph receptor A2	0.035
Mib1	mindbomb homolog 1 (Drosophila)	0.035
Fbxo47	F-box protein 47	0.035
Mmp2	matrix metallopeptidase 2	0.035	Rat
Pdc	phosducin	0.035
Pgf	placental growth factor	0.035
Tbx1	T-box 1	0.035
Chd2	chromodomain helicase DNA binding protein 2	0.035
Thbs3	thrombospondin 3	0.035	Mouse
Igbp1	immunoglobulin (CD79A) binding protein 1	0.035
F2r	coagulation factor II (thrombin) receptor	0.035
U46068	cDNA sequence U46068	0.035
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.035
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.034
Kdm2b	lysine (K)-specific demethylase 2B	0.034
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.034	Mouse
Atr	ataxia telangiectasia and Rad3 related	0.034
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.034
Klf7	Kruppel-like factor 7 (ubiquitous)	0.034
Wnt10b	wingless related MMTV integration site 10b	0.034
Ccnb1	cyclin B1	0.034
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.034
Ube2o	ubiquitin-conjugating enzyme E2O	0.034
Pam	peptidylglycine alpha-amidating monooxygenase	0.034
Prx	periaxin	0.034
Arrb2	arrestin, beta 2	0.034
Prl3d1	prolactin family 3, subfamily d, member 1	0.034
Il1r2	interleukin 1 receptor, type II	0.034
Phospho1	phosphatase, orphan 1	0.034
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.033
Ctgf	connective tissue growth factor	0.033
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.033
Zap70	zeta-chain (TCR) associated protein kinase	0.033
Aco1	aconitase 1	0.033
Csf1	colony stimulating factor 1 (macrophage)	0.033
Pnpla2	patatin-like phospholipase domain containing 2	0.033
Nppb	natriuretic peptide type B	0.033
Chi3l1	chitinase 3-like 1	0.033
Wwtr1	WW domain containing transcription regulator 1	0.033
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.032
Ccl2	chemokine (C-C motif) ligand 2	0.032
Irs2	insulin receptor substrate 2	0.032
Fzd4	frizzled homolog 4 (Drosophila)	0.032
Cdk4	cyclin-dependent kinase 4	0.032
Smad1	MAD homolog 1 (Drosophila)	0.032
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.032
Ltc4s	leukotriene C4 synthase	0.032
Hrh1	histamine receptor H1	0.032
Lyst	lysosomal trafficking regulator	0.032
Ifng	interferon gamma	0.032
Fabp4	fatty acid binding protein 4, adipocyte	0.032
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.032
Usp14	ubiquitin specific peptidase 14	0.032
Irs1	insulin receptor substrate 1	0.032
Cisd2	CDGSH iron sulfur domain 2	0.031
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.031
Gabarapl1	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1	0.031
Lum	lumican	0.031
Ngp	neutrophilic granule protein	0.031
Ptgds	prostaglandin D2 synthase (brain)	0.031
Hoxa3	homeobox A3	0.031
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.031
Esd	esterase D/formylglutathione hydrolase	0.031
H2afx	H2A histone family, member X	0.031
Upk2	uroplakin 2	0.031
Nmur1	neuromedin U receptor 1	0.031
Itgb5	integrin beta 5	0.031
Rdh10	retinol dehydrogenase 10 (all-trans)	0.030
Prp2	proline rich protein 2	0.030
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.030
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.030
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.030
Dbi	diazepam binding inhibitor	0.030
Yap1	yes-associated protein 1	0.030
Slc12a4	solute carrier family 12, member 4	0.030
Mcpt8	mast cell protease 8	0.030
Pnmt	phenylethanolamine-N-methyltransferase	0.030
Camp	cathelicidin antimicrobial peptide	0.030
Mc4r	melanocortin 4 receptor	0.030
Alad	aminolevulinate, delta-, dehydratase	0.030
Paics	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase	0.030
Cxcr4	chemokine (C-X-C motif) receptor 4	0.030
Stub1	STIP1 homology and U-Box containing protein 1	0.030
Rbbp4	retinoblastoma binding protein 4	0.030
Fyn	Fyn proto-oncogene	0.030
L3mbtl2	l(3)mbt-like 2 (Drosophila)	0.030
Rab25	RAB25, member RAS oncogene family	0.030
Ar	androgen receptor	0.030
Rassf1	Ras association (RalGDS/AF-6) domain family member 1	0.030
Opa1	optic atrophy 1 homolog (human)	0.030	Worm
Creg1	cellular repressor of E1A-stimulated genes 1	0.029
Mef2a	myocyte enhancer factor 2A	0.029
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.029
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.029
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.029
Nppa	natriuretic peptide type A	0.029
Ppp1r1a	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.029
Lpin1	lipin 1	0.029
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.029
Ppara	peroxisome proliferator activated receptor alpha	0.029
Timp2	tissue inhibitor of metalloproteinase 2	0.029
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.029
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.029	Rat
Ren1	renin 1 structural	0.029
Necap2	NECAP endocytosis associated 2	0.029
Runx1	runt related transcription factor 1	0.029
Flt3	FMS-like tyrosine kinase 3	0.029
Trim43a	tripartite motif-containing 43A	0.029
Dusp16	dual specificity phosphatase 16	0.029
Slc2a5	solute carrier family 2 (facilitated glucose transporter), member 5	0.028
Prc1	protein regulator of cytokinesis 1	0.028
Sorbs3	sorbin and SH3 domain containing 3	0.028
Ubc	ubiquitin C	0.028
Gsdma3	gasdermin A3	0.028
Casp3	caspase 3	0.028
Senp2	SUMO/sentrin specific peptidase 2	0.028
Asprv1	aspartic peptidase, retroviral-like 1	0.028
Apoa1	apolipoprotein A-I	0.028
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.028
Cst8	cystatin 8 (cystatin-related epididymal spermatogenic)	0.028
Stk11	serine/threonine kinase 11	0.028
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.028
Ptpn23	protein tyrosine phosphatase, non-receptor type 23	0.028
Ccne2	cyclin E2	0.028
Lass2	LAG1 homolog, ceramide synthase 2	0.028
Hspa1a	heat shock protein 1A	0.028
Cidec	cell death-inducing DFFA-like effector c	0.028
Pld2	phospholipase D2	0.028	Rat
Txnrd1	thioredoxin reductase 1	0.028	Rat
Adora3	adenosine A3 receptor	0.028
Pitpnm1	phosphatidylinositol transfer protein, membrane-associated 1	0.028
Fam96a	family with sequence similarity 96, member A	0.028
Hrg	histidine-rich glycoprotein	0.027
Bglap	bone gamma carboxyglutamate protein	0.027
Inpp4a	inositol polyphosphate-4-phosphatase, type I	0.027
Fbln1	fibulin 1	0.027	Mouse
Xpa	xeroderma pigmentosum, complementation group A	0.027
Otc	ornithine transcarbamylase	0.027
Rarb	retinoic acid receptor, beta	0.027
Ptrf	polymerase I and transcript release factor	0.027
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.027
Hlx	H2.0-like homeobox	0.027
Hspa1l	heat shock protein 1-like	0.027
Papolb	poly (A) polymerase beta (testis specific)	0.027
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.027
Mfap2	microfibrillar-associated protein 2	0.027
Lamc2	laminin, gamma 2	0.027
Adrbk1	adrenergic receptor kinase, beta 1	0.027	Rat
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.027
Bhlhe40	basic helix-loop-helix family, member e40	0.027
Fosb	FBJ osteosarcoma oncogene B	0.027
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.027	Rat
Cbl	Casitas B-lineage lymphoma	0.027
Stk40	serine/threonine kinase 40	0.027
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.027
Afg3l2	AFG3(ATPase family gene 3)-like 2 (yeast)	0.027
Met	met proto-oncogene	0.027	Human
Pdpn	podoplanin	0.027
Plxna1	plexin A1	0.027
Cbr1	carbonyl reductase 1	0.026
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.026
Gpr3	G-protein coupled receptor 3	0.026
Shank2	SH3/ankyrin domain gene 2	0.026
Iqgap1	IQ motif containing GTPase activating protein 1	0.026
Col16a1	collagen, type XVI, alpha 1	0.026
Rim4	recombination induced mutation 4	0.026
Bmx	BMX non-receptor tyrosine kinase	0.026	Mouse
Epn2	epsin 2	0.026
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.026
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.026
Srxn1	sulfiredoxin 1 homolog (S. cerevisiae)	0.026
Gsta4	glutathione S-transferase, alpha 4	0.026	Mouse
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.026
Adam17	a disintegrin and metallopeptidase domain 17	0.026
Kdm1a	lysine (K)-specific demethylase 1A	0.026
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.026
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.026
Clic3	chloride intracellular channel 3	0.026
Klc2	kinesin light chain 2	0.026
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.026
Scarb2	scavenger receptor class B, member 2	0.026	Mouse
St6galnac2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	0.026
Rnf128	ring finger protein 128	0.026
Arc	activity regulated cytoskeletal-associated protein	0.026
Wisp2	WNT1 inducible signaling pathway protein 2	0.026
Cdk18	cyclin-dependent kinase 18	0.026
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.026
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.026
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.026
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.026
Cul4b	cullin 4B	0.025
Beta-s	hemoglobin subunit beta-1-like	0.025
Grasp	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	0.025
Zfp598	zinc finger protein 598	0.025
Adprhl2	ADP-ribosylhydrolase like 2	0.025
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.025
Pdgfb	platelet derived growth factor, B polypeptide	0.025
Rasal1	RAS protein activator like 1 (GAP1 like)	0.025
Omd	osteomodulin	0.025
Nfil3	nuclear factor, interleukin 3, regulated	0.025
Flna	filamin, alpha	0.025
Aurkb	aurora kinase B	0.025
Rhob	ras homolog gene family, member B	0.025	Human
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.025
Ffar3	free fatty acid receptor 3	0.025
Hbegf	heparin-binding EGF-like growth factor	0.025
1810019N24Rik	RIKEN cDNA 1810019N24 gene	0.025
Jup	junction plakoglobin	0.025
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.025
Fstl3	follistatin-like 3	0.025
Cys1	cystin 1	0.025
Tnnt2	troponin T2, cardiac	0.025
Retn	resistin	0.025
Gaa	glucosidase, alpha, acid	0.025
Aqp2	aquaporin 2	0.025
Mettl7a1	methyltransferase like 7A1	0.025
Bdkrb1	bradykinin receptor, beta 1	0.025
Epb4.9	erythrocyte protein band 4.9	0.025
Ctsl	cathepsin L	0.025
Arl8b	ADP-ribosylation factor-like 8B	0.025
Eya1	eyes absent 1 homolog (Drosophila)	0.025
Ereg	epiregulin	0.025
T2	brachyury 2	0.025
Prdx2	peroxiredoxin 2	0.025
Stra8	stimulated by retinoic acid gene 8	0.024
Gja1	gap junction protein, alpha 1	0.024
Slc7a5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.024
Gstm6	glutathione S-transferase, mu 6	0.024
Foxf1a	forkhead box F1a	0.024
Stk10	serine/threonine kinase 10	0.024
Tsc1	tuberous sclerosis 1	0.024
Lage3	L antigen family, member 3	0.024
Tuba4a	tubulin, alpha 4A	0.024
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.024
Adipoq	adiponectin, C1Q and collagen domain containing	0.024
Diap1	diaphanous homolog 1 (Drosophila)	0.024
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.024
Npy1r	neuropeptide Y receptor Y1	0.024
Stk4	serine/threonine kinase 4	0.024
Nbn	nibrin	0.024
Smoc2	SPARC related modular calcium binding 2	0.024
Eif2s3y	eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked	0.024
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.024	Rat
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.024	Rat
L1cam	L1 cell adhesion molecule	0.024
Stc1	stanniocalcin 1	0.024
Pde12	phosphodiesterase 12	0.024
Kif3a	kinesin family member 3A	0.024
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.024
Fgf7	fibroblast growth factor 7	0.024
Jun	Jun oncogene	0.024	Rat
Cct6b	chaperonin containing Tcp1, subunit 6b (zeta)	0.024
Cxadr	coxsackie virus and adenovirus receptor	0.024
Gcet2	germinal center expressed transcript 2	0.024
Inpp5d	inositol polyphosphate-5-phosphatase D	0.024
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.023
Pcp2	Purkinje cell protein 2 (L7)	0.023
Hmx3	H6 homeobox 3	0.023
Immt	inner membrane protein, mitochondrial	0.023
Hgd	homogentisate 1, 2-dioxygenase	0.023
Grm1	glutamate receptor, metabotropic 1	0.023
Xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	0.023
Il17ra	interleukin 17 receptor A	0.023
Crlf1	cytokine receptor-like factor 1	0.023
Ddx3y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.023
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.023
Akr1c6	aldo-keto reductase family 1, member C6	0.023
AU021092	expressed sequence AU021092	0.023
Sva	seminal vesicle antigen	0.023
Oprm1	opioid receptor, mu 1	0.023
Gm2223	predicted pseudogene 2223	0.023
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.023	Rat
Ndufs6	NADH dehydrogenase (ubiquinone) Fe-S protein 6	0.023
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.023
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.023
Tshr	thyroid stimulating hormone receptor	0.023
Edn1	endothelin 1	0.023
Kif20a	kinesin family member 20A	0.023
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.023
Bcor	BCL6 interacting corepressor	0.023
Jak1	Janus kinase 1	0.023
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.023
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.023
Rrm2	ribonucleotide reductase M2	0.023
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.023
Bsn	bassoon	0.023
Nf1	neurofibromatosis 1	0.023
Git1	G protein-coupled receptor kinase-interactor 1	0.023	Mouse
Gsr	glutathione reductase	0.023	Worm
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.023
Plcb1	phospholipase C, beta 1	0.023
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.023
Metap1	methionyl aminopeptidase 1	0.023
Rhbdf1	rhomboid family 1 (Drosophila)	0.023
Psme3	proteaseome (prosome, macropain) 28 subunit, 3	0.023
Mcm9	minichromosome maintenance complex component 9	0.023
Ercc1	excision repair cross-complementing rodent repair deficiency, complementation group 1	0.023
Apoc4	apolipoprotein C-IV	0.022
Clip1	CAP-GLY domain containing linker protein 1	0.022
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.022
Fam83f	family with sequence similarity 83, member F	0.022
Cpa3	carboxypeptidase A3, mast cell	0.022
Vmn2r26	vomeronasal 2, receptor 26	0.022
Pkd2	polycystic kidney disease 2	0.022
Clec3b	C-type lectin domain family 3, member b	0.022
Myo1d	myosin ID	0.022
Psap	prosaposin	0.022
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.022
Colec12	collectin sub-family member 12	0.022
Rab3a	RAB3A, member RAS oncogene family	0.022
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.022
Mpl	myeloproliferative leukemia virus oncogene	0.022
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.022
Ftl2	ferritin light chain 2	0.022
Men1	multiple endocrine neoplasia 1	0.022
Brd2	bromodomain containing 2	0.022
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.022
Tyrp1	tyrosinase-related protein 1	0.022
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.022
Tcf21	transcription factor 21	0.022
C77027	expressed sequence C77027	0.022
Ptgdr	prostaglandin D receptor	0.022
Il4ra	interleukin 4 receptor, alpha	0.022
Tubb2c	tubulin, beta 2C	0.022
Ndufab1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1	0.022
Cby1	chibby homolog 1 (Drosophila)	0.022
Nrp1	neuropilin 1	0.022
Fosl1	fos-like antigen 1	0.022	Rat
Prkci	protein kinase C, iota	0.022
Trabd	TraB domain containing	0.022
Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	0.022	Mouse Rat
Palm	paralemmin	0.022
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.022
Scn1b	sodium channel, voltage-gated, type I, beta	0.022
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.022
Sult1d1	sulfotransferase family 1D, member 1	0.022
Myh10	myosin, heavy polypeptide 10, non-muscle	0.022
Smad3	MAD homolog 3 (Drosophila)	0.022
A4galt	alpha 1,4-galactosyltransferase	0.022
Hpcal1	hippocalcin-like 1	0.022
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.021
Cd151	CD151 antigen	0.021
Hba-a2	hemoglobin alpha, adult chain 2	0.021
Gcsh	glycine cleavage system protein H (aminomethyl carrier)	0.021
Thra	thyroid hormone receptor alpha	0.021
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.021
Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	0.021
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.021
Emp2	epithelial membrane protein 2	0.021
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.021
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.021
Sult1c1	sulfotransferase family, cytosolic, 1C, member 1	0.021
Hspa1b	heat shock protein 1B	0.021
Ptk7	PTK7 protein tyrosine kinase 7	0.021
Fga	fibrinogen alpha chain	0.021
Birc5	baculoviral IAP repeat-containing 5	0.021
Rhd	Rh blood group, D antigen	0.021
Klf13	Kruppel-like factor 13	0.021
Lat	linker for activation of T cells	0.021
Ahsg	alpha-2-HS-glycoprotein	0.021
Adarb1	adenosine deaminase, RNA-specific, B1	0.021
Inpp5k	inositol polyphosphate 5-phosphatase K	0.021
Atf6	activating transcription factor 6	0.021
Hic1	hypermethylated in cancer 1	0.021
Nphs2	nephrosis 2 homolog, podocin (human)	0.021
Ces1c	carboxylesterase 1C	0.021
Ptprg	protein tyrosine phosphatase, receptor type, G	0.021
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.021
Ddr2	discoidin domain receptor family, member 2	0.021
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.021
Sp3	trans-acting transcription factor 3	0.021
Nt5dc2	5'-nucleotidase domain containing 2	0.021
Hspd1	heat shock protein 1 (chaperonin)	0.021
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.021
Sos1	son of sevenless homolog 1 (Drosophila)	0.021
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.021
Il1rap	interleukin 1 receptor accessory protein	0.021
Sult1b1	sulfotransferase family 1B, member 1	0.021
Axin1	axin 1	0.021
Mtap4	microtubule-associated protein 4	0.021
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.021
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.021
Hrc	histidine rich calcium binding protein	0.021
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.021
Tg	thyroglobulin	0.021
Ecm1	extracellular matrix protein 1	0.020
Arf5	ADP-ribosylation factor 5	0.020
Txn1	thioredoxin 1	0.020	Human
Resp18	regulated endocrine-specific protein 18	0.020
Ccl11	chemokine (C-C motif) ligand 11	0.020
Map2k2	mitogen-activated protein kinase kinase 2	0.020
Car1	carbonic anhydrase 1	0.020
Smr3a	submaxillary gland androgen regulated protein 3A	0.020
Rab12	RAB12, member RAS oncogene family	0.020
S100g	S100 calcium binding protein G	0.020
Tdo2	tryptophan 2,3-dioxygenase	0.020
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.020
Pabpc4	poly(A) binding protein, cytoplasmic 4	0.020
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.020
Ankrd40	ankyrin repeat domain 40	0.020
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.020
Adh1	alcohol dehydrogenase 1 (class I)	0.020
Mfap5	microfibrillar associated protein 5	0.020
Krtdap	keratinocyte differentiation associated protein	0.020
Gclm	glutamate-cysteine ligase, modifier subunit	0.020
Faf1	Fas-associated factor 1	0.020
Keg1	kidney expressed gene 1	0.020
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.020
Umod	uromodulin	0.020
Map2k4	mitogen-activated protein kinase kinase 4	0.020
Inppl1	inositol polyphosphate phosphatase-like 1	0.020
Mmp8	matrix metallopeptidase 8	0.020
Aadat	aminoadipate aminotransferase	0.020
March5	membrane-associated ring finger (C3HC4) 5	0.020
Flt3l	FMS-like tyrosine kinase 3 ligand	0.020
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.020
Mafg	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)	0.020