IMP
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hematopoietic stem cell differentiation
The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "hematopoietic stem cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Neurod1 | neurogenic differentiation 1 | 0.923 | Mouse | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.694 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.663 | ||
| Ccnd1 | cyclin D1 | 0.651 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.578 | ||
| Ccnd2 | cyclin D2 | 0.350 | ||
| Sfrp2 | secreted frizzled-related protein 2 | 0.339 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.310 | ||
| Ptf1a | pancreas specific transcription factor, 1a | 0.309 | Mouse | |
| Uncx | UNC homeobox | 0.292 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.274 | ||
| Tcf15 | transcription factor 15 | 0.227 | Mouse | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.213 | ||
| Dsg4 | desmoglein 4 | 0.202 | ||
| Gata1 | GATA binding protein 1 | 0.190 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.188 | ||
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.187 | ||
| Pax6 | paired box gene 6 | 0.172 | ||
| Gfra3 | glial cell line derived neurotrophic factor family receptor alpha 3 | 0.117 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.113 | Mouse | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.101 | ||
| Neurog2 | neurogenin 2 | 0.097 | Mouse | |
| Onecut1 | one cut domain, family member 1 | 0.093 | ||
| Shh | sonic hedgehog | 0.092 | ||
| Gata4 | GATA binding protein 4 | 0.090 | ||
| Mecom | MDS1 and EVI1 complex locus | 0.088 | ||
| Hoxc5 | homeobox C5 | 0.087 | ||
| Efna2 | ephrin A2 | 0.086 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.085 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.080 | ||
| Gsc | goosecoid homeobox | 0.080 | ||
| Srebf2 | sterol regulatory element binding factor 2 | 0.078 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.069 | ||
| Hoxb5 | homeobox B5 | 0.066 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.065 | ||
| En1 | engrailed 1 | 0.064 | ||
| Dlx2 | distal-less homeobox 2 | 0.062 | ||
| Crb2 | crumbs homolog 2 (Drosophila) | 0.062 | ||
| Insm1 | insulinoma-associated 1 | 0.059 | ||
| Prph | peripherin | 0.057 | ||
| Pax3 | paired box gene 3 | 0.056 | ||
| Myog | myogenin | 0.054 | ||
| Cbfa2t3 | core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) | 0.052 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.051 | ||
| Foxf1a | forkhead box F1a | 0.047 | ||
| Nkx3-2 | NK3 homeobox 2 | 0.047 | ||
| Tlx3 | T-cell leukemia, homeobox 3 | 0.046 | ||
| Smu1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 0.045 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.045 | ||
| Hoxc6 | homeobox C6 | 0.045 | ||
| Six5 | sine oculis-related homeobox 5 homolog (Drosophila) | 0.045 | ||
| Anapc4 | anaphase promoting complex subunit 4 | 0.045 | ||
| Hoxd13 | homeobox D13 | 0.043 | ||
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.042 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.041 | Mouse | |
| Smn1 | survival motor neuron 1 | 0.041 | ||
| Nhlh1 | nescient helix loop helix 1 | 0.041 | Mouse | |
| Rim4 | recombination induced mutation 4 | 0.040 | ||
| Lep | leptin | 0.040 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.038 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.038 | ||
| Tbx5 | T-box 5 | 0.037 | ||
| Has2 | hyaluronan synthase 2 | 0.037 | ||
| Cpsf3 | cleavage and polyadenylation specificity factor 3 | 0.036 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.036 | ||
| Foxd3 | forkhead box D3 | 0.035 | ||
| Hoxa11 | homeobox A11 | 0.035 | ||
| Des | desmin | 0.034 | ||
| Shox2 | short stature homeobox 2 | 0.034 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.034 | ||
| Nbn | nibrin | 0.034 | ||
| Nkx2-9 | NK2 transcription factor related, locus 9 (Drosophila) | 0.034 | ||
| Foxd2 | forkhead box D2 | 0.033 | ||
| Gpr50 | G-protein-coupled receptor 50 | 0.032 | ||
| Myh7 | myosin, heavy polypeptide 7, cardiac muscle, beta | 0.031 | ||
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.031 | ||
| Il21r | interleukin 21 receptor | 0.031 | ||
| Meox2 | mesenchyme homeobox 2 | 0.031 | ||
| Hoxb1 | homeobox B1 | 0.031 | ||
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.031 | ||
| Epor | erythropoietin receptor | 0.031 | ||
| Nrarp | Notch-regulated ankyrin repeat protein | 0.031 | ||
| Phldb2 | pleckstrin homology-like domain, family B, member 2 | 0.031 | ||
| Dok1 | docking protein 1 | 0.030 | ||
| Fgf15 | fibroblast growth factor 15 | 0.030 | ||
| Lhx5 | LIM homeobox protein 5 | 0.029 | ||
| Tcf3 | transcription factor 3 | 0.029 | ||
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.029 | ||
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.028 | ||
| Ttn | titin | 0.028 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.028 | ||
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.028 | ||
| Hoxa5 | homeobox A5 | 0.028 | ||
| Mybpc3 | myosin binding protein C, cardiac | 0.028 | ||
| Lhx6 | LIM homeobox protein 6 | 0.028 | ||
| Col22a1 | collagen, type XXII, alpha 1 | 0.027 | ||
| Madcam1 | mucosal vascular addressin cell adhesion molecule 1 | 0.027 | ||
| Isl2 | insulin related protein 2 (islet 2) | 0.027 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.027 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.026 | ||
| Hoxd3 | homeobox D3 | 0.026 | ||
| Edn3 | endothelin 3 | 0.026 | ||
| Twist1 | twist homolog 1 (Drosophila) | 0.025 | Mouse | |
| Neurog1 | neurogenin 1 | 0.025 | Mouse | |
| Msx2 | homeobox, msh-like 2 | 0.025 | ||
| Barx1 | BarH-like homeobox 1 | 0.024 | ||
| Hoxa10 | homeobox A10 | 0.024 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.024 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.024 | ||
| Neurod4 | neurogenic differentiation 4 | 0.024 | Mouse | |
| Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.023 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.023 | ||
| Sox14 | SRY-box containing gene 14 | 0.023 | ||
| Sox11 | SRY-box containing gene 11 | 0.023 | ||
| Neurog3 | neurogenin 3 | 0.023 | Mouse | |
| Mrvi1 | MRV integration site 1 | 0.022 | ||
| Dmpk | dystrophia myotonica-protein kinase | 0.022 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.022 | ||
| Ldb3 | LIM domain binding 3 | 0.022 | ||
| Hoxa1 | homeobox A1 | 0.021 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.021 | ||
| Ush1g | Usher syndrome 1G homolog (human) | 0.021 | ||
| Capn6 | calpain 6 | 0.021 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.021 | ||
| Nfe2 | nuclear factor, erythroid derived 2 | 0.020 | ||
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.020 | ||
| Dbh | dopamine beta hydroxylase | 0.020 | ||
| Pitx3 | paired-like homeodomain transcription factor 3 | 0.020 | ||
| Sfrp5 | secreted frizzled-related sequence protein 5 | 0.020 | ||
| Plrg1 | pleiotropic regulator 1, PRL1 homolog (Arabidopsis) | 0.020 | ||
| Sox2 | SRY-box containing gene 2 | 0.020 | ||
| Hoxc4 | homeobox C4 | 0.020 | ||
| Wrn | Werner syndrome homolog (human) | 0.020 | ||
| Foxc2 | forkhead box C2 | 0.020 | ||
| Aimp1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | 0.020 | ||
| Sim2 | single-minded homolog 2 (Drosophila) | 0.020 | ||
| Irx1 | Iroquois related homeobox 1 (Drosophila) | 0.019 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.019 | ||
| Dlk1 | delta-like 1 homolog (Drosophila) | 0.019 | ||
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.019 | ||
| Sox1 | SRY-box containing gene 1 | 0.019 | ||
| Gnrh1 | gonadotropin releasing hormone 1 | 0.019 | ||
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.019 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.019 | Zebrafish | |
| Hoxa7 | homeobox A7 | 0.018 | ||
| Evx1 | even skipped homeotic gene 1 homolog | 0.018 | ||
| Epx | eosinophil peroxidase | 0.018 | ||
| Foxo1 | forkhead box O1 | 0.018 | ||
| Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | 0.018 | ||
| Hoxb2 | homeobox B2 | 0.018 | ||
| Nat3 | N-acetyltransferase 3 | 0.018 | ||
| Psen2 | presenilin 2 | 0.018 | ||
| Mta2 | metastasis-associated gene family, member 2 | 0.018 | ||
| Myf5 | myogenic factor 5 | 0.018 | ||
| Srrm4 | serine/arginine repetitive matrix 4 | 0.018 | ||
| Ins2 | insulin II | 0.017 | ||
| Fgf17 | fibroblast growth factor 17 | 0.017 | ||
| Ccnd3 | cyclin D3 | 0.017 | ||
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.017 | ||
| Ebf2 | early B-cell factor 2 | 0.017 | ||
| Tbx20 | T-box 20 | 0.017 | ||
| Hoxb4 | homeobox B4 | 0.017 | Human | |
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.017 | ||
| Gdf11 | growth differentiation factor 11 | 0.016 | ||
| Hnrnpf | heterogeneous nuclear ribonucleoprotein F | 0.016 | ||
| Hopx | HOP homeobox | 0.016 | ||
| Sar1a | SAR1 gene homolog A (S. cerevisiae) | 0.016 | ||
| Irx4 | Iroquois related homeobox 4 (Drosophila) | 0.016 | ||
| Galr1 | galanin receptor 1 | 0.016 | ||
| Cops4 | COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana) | 0.016 | ||
| Sost | sclerostin | 0.016 | ||
| Phox2b | paired-like homeobox 2b | 0.016 | ||
| 2700060E02Rik | RIKEN cDNA 2700060E02 gene | 0.016 | ||
| U2af1 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 | 0.016 | ||
| Ebf3 | early B-cell factor 3 | 0.016 | ||
| Nrk | Nik related kinase | 0.016 | ||
| Fgf16 | fibroblast growth factor 16 | 0.016 | ||
| Fes | feline sarcoma oncogene | 0.016 | ||
| Gtl3 | gene trap locus 3 | 0.016 | ||
| Runx1t1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.015 | ||
| Foxo4 | forkhead box O4 | 0.015 | ||
| Dcc | deleted in colorectal carcinoma | 0.015 | ||
| Ptx3 | pentraxin related gene | 0.015 | ||
| Bglap | bone gamma carboxyglutamate protein | 0.015 | ||
| Irs4 | insulin receptor substrate 4 | 0.015 | ||
| Hif3a | hypoxia inducible factor 3, alpha subunit | 0.015 | ||
| Hmga2 | high mobility group AT-hook 2 | 0.015 | ||
| Hic1 | hypermethylated in cancer 1 | 0.015 | ||
| Myl3 | myosin, light polypeptide 3 | 0.015 | ||
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.015 | ||
| Sim1 | single-minded homolog 1 (Drosophila) | 0.015 | ||
| Hoxa13 | homeobox A13 | 0.015 | ||
| Lmo2 | LIM domain only 2 | 0.015 | ||
| Lhx9 | LIM homeobox protein 9 | 0.015 | ||
| Bnc1 | basonuclin 1 | 0.015 | ||
| Msx1 | homeobox, msh-like 1 | 0.015 | ||
| Fgf4 | fibroblast growth factor 4 | 0.015 | ||
| Sall3 | sal-like 3 (Drosophila) | 0.014 | ||
| Apex1 | apurinic/apyrimidinic endonuclease 1 | 0.014 | ||
| Mlh1 | mutL homolog 1 (E. coli) | 0.014 | ||
| Hmx1 | H6 homeobox 1 | 0.014 | ||
| Glra1 | glycine receptor, alpha 1 subunit | 0.014 | ||
| Magel2 | melanoma antigen, family L, 2 | 0.014 | ||
| Insr | insulin receptor | 0.014 | ||
| Tnni3 | troponin I, cardiac 3 | 0.014 | ||
| Pax9 | paired box gene 9 | 0.014 | ||
| Dnajc5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.014 | ||
| Igfbpl1 | insulin-like growth factor binding protein-like 1 | 0.014 | ||
| Gata2 | GATA binding protein 2 | 0.014 | ||
| Pou2f2 | POU domain, class 2, transcription factor 2 | 0.014 | ||
| Trim10 | tripartite motif-containing 10 | 0.014 | ||
| Nfatc4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 0.014 | ||
| Adcy4 | adenylate cyclase 4 | 0.014 | ||
| Sox7 | SRY-box containing gene 7 | 0.014 | ||
| Elk3 | ELK3, member of ETS oncogene family | 0.013 | ||
| Lag3 | lymphocyte-activation gene 3 | 0.013 | ||
| Gdf15 | growth differentiation factor 15 | 0.013 | ||
| Cfdp1 | craniofacial development protein 1 | 0.013 | ||
| Cdca3 | cell division cycle associated 3 | 0.013 | ||
| Igf2bp2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.013 | ||
| Mfng | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.013 | ||
| Ina | internexin neuronal intermediate filament protein, alpha | 0.013 | ||
| Hoxd12 | homeobox D12 | 0.013 | ||
| Rbmxrt | RNA binding motif protein, X chromosome retrogene | 0.013 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.013 | ||
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.013 | ||
| Ermap | erythroblast membrane-associated protein | 0.013 | ||
| Myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.013 | ||
| Nkx2-4 | NK2 transcription factor related, locus 4 (Drosophila) | 0.013 | ||
| Alx3 | aristaless-like homeobox 3 | 0.013 | ||
| Etv4 | ets variant gene 4 (E1A enhancer binding protein, E1AF) | 0.013 | ||
| Parl | presenilin associated, rhomboid-like | 0.013 | ||
| Ptgir | prostaglandin I receptor (IP) | 0.012 | ||
| Ccrl2 | chemokine (C-C motif) receptor-like 2 | 0.012 | ||
| Eya4 | eyes absent 4 homolog (Drosophila) | 0.012 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.012 | ||
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.012 | ||
| Hnf1a | HNF1 homeobox A | 0.012 | ||
| Gsx2 | GS homeobox 2 | 0.012 | ||
| Mnx1 | motor neuron and pancreas homeobox 1 | 0.012 | ||
| Myom1 | myomesin 1 | 0.012 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.012 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.012 | ||
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.012 | ||
| Cpa1 | carboxypeptidase A1 | 0.012 | ||
| Sox3 | SRY-box containing gene 3 | 0.012 | ||
| Dlx1 | distal-less homeobox 1 | 0.012 | ||
| Fgf6 | fibroblast growth factor 6 | 0.011 | ||
| Hoxb6 | homeobox B6 | 0.011 | ||
| D10Wsu52e | DNA segment, Chr 10, Wayne State University 52, expressed | 0.011 | ||
| Prx | periaxin | 0.011 | ||
| Scrt2 | scratch homolog 2, zinc finger protein (Drosophila) | 0.011 | ||
| Prox1 | prospero-related homeobox 1 | 0.011 | ||
| Zscan2 | zinc finger and SCAN domain containing 2 | 0.011 | ||
| Akp3 | alkaline phosphatase 3, intestine, not Mn requiring | 0.011 | ||
| Gcm1 | glial cells missing homolog 1 (Drosophila) | 0.011 | ||
| BC020535 | cDNA sequence BC020535 | 0.011 | ||
| Ankrd1 | ankyrin repeat domain 1 (cardiac muscle) | 0.011 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.011 | ||
| Lmo1 | LIM domain only 1 | 0.011 | ||
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.011 | ||
| She | src homology 2 domain-containing transforming protein E | 0.011 | ||
| Btbd17 | BTB (POZ) domain containing 17 | 0.011 | ||
| Grm1 | glutamate receptor, metabotropic 1 | 0.011 | ||
| Gata6 | GATA binding protein 6 | 0.011 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.011 | ||
| Popdc3 | popeye domain containing 3 | 0.010 | ||
| Retnlb | resistin like beta | 0.010 | ||
| Pax1 | paired box gene 1 | 0.010 | ||
| Runx2 | runt related transcription factor 2 | 0.010 | ||
| Hbb-y | hemoglobin Y, beta-like embryonic chain | 0.010 | ||
| Gja1 | gap junction protein, alpha 1 | 0.010 | ||
| Hoxb13 | homeobox B13 | 0.010 | ||
| Npy2r | neuropeptide Y receptor Y2 | 0.010 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.010 | ||
| Pfdn2 | prefoldin 2 | 0.010 | ||
| Nppa | natriuretic peptide type A | 0.010 | ||
| Tnnc1 | troponin C, cardiac/slow skeletal | 0.010 | ||
| Notch3 | Notch gene homolog 3 (Drosophila) | 0.010 | ||
| Efs | embryonal Fyn-associated substrate | 0.010 | ||
| Ets1 | E26 avian leukemia oncogene 1, 5' domain | 0.010 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.010 | ||
| Hdac1 | histone deacetylase 1 | 0.010 | Zebrafish | |
| Exosc7 | exosome component 7 | 0.010 | ||
| Wnt8b | wingless related MMTV integration site 8b | 0.010 | ||
| Rprm | reprimo, TP53 dependent G2 arrest mediator candidate | 0.010 | ||
| Zbp1 | Z-DNA binding protein 1 | 0.010 |