IMP: Integrative Multi-species Prediction

Mus musculus

22 genes annotated in mouse

mrna catabolic process

The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mrna catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "mrna catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.958
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.899	Yeast
Rc3h1	RING CCCH (C3H) domains 1	0.850
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.821	Yeast
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.767
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.618
Srsf1	serine/arginine-rich splicing factor 1	0.607	Yeast
Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	0.457
Ldb3	LIM domain binding 3	0.343
Hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.278
Btg1	B-cell translocation gene 1, anti-proliferative	0.234
Ddx17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.230	Yeast
Fos	FBJ osteosarcoma oncogene	0.227
Npm1	nucleophosmin 1	0.203
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.188
Snrpe	small nuclear ribonucleoprotein E	0.186
Dusp1	dual specificity phosphatase 1	0.178
Neurl1a	neuralized homolog 1A (Drosophila)	0.165
Cnot6	CCR4-NOT transcription complex, subunit 6	0.161	Human Mouse Fly
Trrap	transformation/transcription domain-associated protein	0.149
Tnrc6b	trinucleotide repeat containing 6b	0.144
Sp1	trans-acting transcription factor 1	0.129
Naa38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.127
Junb	Jun-B oncogene	0.125
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.123
Cetn3	centrin 3	0.122
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.119
Nap1l1	nucleosome assembly protein 1-like 1	0.115
Actl6a	actin-like 6A	0.108
Srsf7	serine/arginine-rich splicing factor 7	0.099
Cnot1	CCR4-NOT transcription complex, subunit 1	0.094
Rbmxrt	RNA binding motif protein, X chromosome retrogene	0.091
Sarnp	SAP domain containing ribonucleoprotein	0.091
Btg2	B-cell translocation gene 2, anti-proliferative	0.089	Human
Pcna	proliferating cell nuclear antigen	0.080
Wdr77	WD repeat domain 77	0.078
Gsk3b	glycogen synthase kinase 3 beta	0.077
Zfp36	zinc finger protein 36	0.077
Tra2b	transformer 2 beta homolog (Drosophila)	0.075
Srsf3	serine/arginine-rich splicing factor 3	0.070
Ier2	immediate early response 2	0.070
Cnot7	CCR4-NOT transcription complex, subunit 7	0.068
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.068
Nono	non-POU-domain-containing, octamer binding protein	0.066
Bptf	bromodomain PHD finger transcription factor	0.065
Hmgn1	high mobility group nucleosomal binding domain 1	0.064
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.061
Srsf6	serine/arginine-rich splicing factor 6	0.061
Jun	Jun oncogene	0.059
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.057	Yeast
Rfx7	regulatory factor X, 7	0.056
Hmgb1	high mobility group box 1	0.055
Hnrpll	heterogeneous nuclear ribonucleoprotein L-like	0.052
Zc3h11a	zinc finger CCCH type containing 11A	0.051
Fam96a	family with sequence similarity 96, member A	0.051
Ptma	prothymosin alpha	0.050
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.049
Trim32	tripartite motif-containing 32	0.049
Srsf2	serine/arginine-rich splicing factor 2	0.046
Tardbp	TAR DNA binding protein	0.046
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.045
Brd4	bromodomain containing 4	0.045
Tbca	tubulin cofactor A	0.044
Gtf2e2	general transcription factor II E, polypeptide 2 (beta subunit)	0.044
Taf9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.044
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.043
Kpna2	karyopherin (importin) alpha 2	0.043
Rbm8a	RNA binding motif protein 8a	0.043	Human
Anp32b	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.043
H3f3a	H3 histone, family 3A	0.042
Nfya	nuclear transcription factor-Y alpha	0.041
Pabpn1	poly(A) binding protein, nuclear 1	0.040
Ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.040
Snrnp40	small nuclear ribonucleoprotein 40 (U5)	0.040
Erh	enhancer of rudimentary homolog (Drosophila)	0.040
Zfp322a	zinc finger protein 322A	0.039
2700029M09Rik	RIKEN cDNA 2700029M09 gene	0.039
Ssbp1	single-stranded DNA binding protein 1	0.038
Hdac2	histone deacetylase 2	0.038
Pabpc1	poly(A) binding protein, cytoplasmic 1	0.037
Polr2h	polymerase (RNA) II (DNA directed) polypeptide H	0.037
Uba2	ubiquitin-like modifier activating enzyme 2	0.036
Lig4	ligase IV, DNA, ATP-dependent	0.036
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.036
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.036
Actn2	actinin alpha 2	0.035
Egr1	early growth response 1	0.034
Nlk	nemo like kinase	0.034
Snrpb2	U2 small nuclear ribonucleoprotein B	0.034
Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.034
Psmg2	proteasome (prosome, macropain) assembly chaperone 2	0.033
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.033
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.033
Nanos2	nanos homolog 2 (Drosophila)	0.033
Pcbp1	poly(rC) binding protein 1	0.032
Chfr	checkpoint with forkhead and ring finger domains	0.031
Klf6	Kruppel-like factor 6	0.030
Btf3	basic transcription factor 3	0.030
Smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.030
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.029
Gpatch8	G patch domain containing 8	0.029
Ubp1	upstream binding protein 1	0.029
Sumo2	SMT3 suppressor of mif two 3 homolog 2 (yeast)	0.029
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.029
Tmem123	transmembrane protein 123	0.028
Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.028
Ncoa3	nuclear receptor coactivator 3	0.028
Ttc13	tetratricopeptide repeat domain 13	0.028
Srsf10	serine/arginine-rich splicing factor 10	0.028
Pum1	pumilio 1 (Drosophila)	0.027	Yeast
Rpa3	replication protein A3	0.027
Pias1	protein inhibitor of activated STAT 1	0.027
Tfdp1	transcription factor Dp 1	0.027
Dido1	death inducer-obliterator 1	0.027
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.027
Mau2	MAU2 chromatid cohesion factor homolog (C. elegans)	0.027
Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.027
Mael	maelstrom homolog (Drosophila)	0.026
Hnrnph3	heterogeneous nuclear ribonucleoprotein H3	0.026
Thoc4	THO complex 4	0.026
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.026
Atf3	activating transcription factor 3	0.026
0610009D07Rik	RIKEN cDNA 0610009D07 gene	0.025
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.025
Zranb2	zinc finger, RAN-binding domain containing 2	0.024
Brd2	bromodomain containing 2	0.024
Luc7l3	LUC7-like 3 (S. cerevisiae)	0.024
Ranbp1	RAN binding protein 1	0.024
Ccdc58	coiled-coil domain containing 58	0.023
Kpnb1	karyopherin (importin) beta 1	0.023
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.023
Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.023
Cacybp	calcyclin binding protein	0.023
Lmna	lamin A	0.023
Dtymk	deoxythymidylate kinase	0.022
Caprin1	cell cycle associated protein 1	0.022
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.022
Fcf1	FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)	0.022
Cetn2	centrin 2	0.022
Sbno1	sno, strawberry notch homolog 1 (Drosophila)	0.022
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.022
Midn	midnolin	0.021
Wbp7	WW domain binding protein 7	0.021
Fam192a	family with sequence similarity 192, member A	0.021
Ran	RAN, member RAS oncogene family	0.021
Rc3h2	ring finger and CCCH-type zinc finger domains 2	0.021	Mouse
Hnrnpul1	heterogeneous nuclear ribonucleoprotein U-like 1	0.021
Xrn1	5'-3' exoribonuclease 1	0.021
Nudcd2	NudC domain containing 2	0.021
Dhx9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.021
Bms1	BMS1 homolog, ribosome assembly protein (yeast)	0.021
Med13	mediator complex subunit 13	0.021
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.021
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.021
Ilf2	interleukin enhancer binding factor 2	0.021
Zmym4	zinc finger, MYM-type 4	0.021
Ube2n	ubiquitin-conjugating enzyme E2N	0.020
Prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.020
Tcf12	transcription factor 12	0.020
Tdp2	tyrosyl-DNA phosphodiesterase 2	0.020
Prpf4b	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	0.020
Zfc3h1	zinc finger, C3H1-type containing	0.020
LOC433064	peptidyl-prolyl cis-trans isomerase H-like	0.019
Fbxo11	F-box protein 11	0.019
Lnpep	leucyl/cystinyl aminopeptidase	0.019
Ptk2	PTK2 protein tyrosine kinase 2	0.019
Nsun2	NOL1/NOP2/Sun domain family member 2	0.019
Tia1	cytotoxic granule-associated RNA binding protein 1	0.019	Yeast
Elf1	E74-like factor 1	0.019
Gm12372	predicted gene 12372	0.019
Cenpc1	centromere protein C1	0.019
Wnk1	WNK lysine deficient protein kinase 1	0.019
Cfdp1	craniofacial development protein 1	0.019
Snrpg	small nuclear ribonucleoprotein polypeptide G	0.019
Cd28	CD28 antigen	0.019
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.018
Cnot2	CCR4-NOT transcription complex, subunit 2	0.018
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.018
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.018
Mcl1	myeloid cell leukemia sequence 1	0.018
Nr2c2	nuclear receptor subfamily 2, group C, member 2	0.018
Tnrc6c	trinucleotide repeat containing 6C	0.018	Human
Rpl22	ribosomal protein L22	0.018
Morc2a	microrchidia 2A	0.017
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.017
Snrpd1	small nuclear ribonucleoprotein D1	0.017
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.017
Cks2	CDC28 protein kinase regulatory subunit 2	0.017
Faim	Fas apoptotic inhibitory molecule	0.017
Rbm14	RNA binding motif protein 14	0.017
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.016
Purb	purine rich element binding protein B	0.016
Synrg	synergin, gamma	0.016
Utp18	UTP18, small subunit (SSU) processome component, homolog (yeast)	0.016
Xpo1	exportin 1, CRM1 homolog (yeast)	0.016
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.016
Prrc2c	proline-rich coiled-coil 2C	0.016
Cul4b	cullin 4B	0.016
Slbp	stem-loop binding protein	0.016
Csrnp1	cysteine-serine-rich nuclear protein 1	0.015
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.015
Naf1	nuclear assembly factor 1 homolog (S. cerevisiae)	0.015
Zfp329	zinc finger protein 329	0.015
Nudt21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.015
Irf2bp2	interferon regulatory factor 2 binding protein 2	0.015
5830433M19Rik	RIKEN cDNA 5830433M19 gene	0.015
Ythdf2	YTH domain family 2	0.015
Mex3c	mex3 homolog C (C. elegans)	0.014
Zfp207	zinc finger protein 207	0.014
E130309D02Rik	RIKEN cDNA E130309D02 gene	0.014
Hspa14	heat shock protein 14	0.014
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.014
Ankhd1	ankyrin repeat and KH domain containing 1	0.014
Rcor1	REST corepressor 1	0.014
Znrf2	zinc and ring finger 2	0.014
Ammecr1l	AMME chromosomal region gene 1-like	0.014
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.013
Taf4a	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.013
Casp8ap2	caspase 8 associated protein 2	0.013
Taok1	TAO kinase 1	0.013
Seh1l	SEH1-like (S. cerevisiae	0.013
Scrib	scribbled homolog (Drosophila)	0.013
Ebna1bp2	EBNA1 binding protein 2	0.013
Klf7	Kruppel-like factor 7 (ubiquitous)	0.013
Zfp326	zinc finger protein 326	0.013
Map2k3	mitogen-activated protein kinase kinase 3	0.013
Ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.013
Ttc27	tetratricopeptide repeat domain 27	0.013
Csnk1g1	casein kinase 1, gamma 1	0.013
Mrfap1	Morf4 family associated protein 1	0.013
Tipin	timeless interacting protein	0.013
Zbtb1	zinc finger and BTB domain containing 1	0.013
Egr2	early growth response 2	0.012
Fam168b	family with sequence similarity 168, member B	0.012
Zfp148	zinc finger protein 148	0.012
Lsm3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.012
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
Rasal1	RAS protein activator like 1 (GAP1 like)	0.012
Pde7a	phosphodiesterase 7A	0.012
Cbll1	Casitas B-lineage lymphoma-like 1	0.012
Api5	apoptosis inhibitor 5	0.012
Hnrnpf	heterogeneous nuclear ribonucleoprotein F	0.012
Ewsr1	Ewing sarcoma breakpoint region 1	0.012
Pnpla2	patatin-like phospholipase domain containing 2	0.012
Grm1	glutamate receptor, metabotropic 1	0.012
Rdbp	RD RNA-binding protein	0.012
Armc10	armadillo repeat containing 10	0.012
Nipbl	Nipped-B homolog (Drosophila)	0.012
Nup188	nucleoporin 188	0.012
Ifrd2	interferon-related developmental regulator 2	0.012
Sesn1	sestrin 1	0.012
Pdcd4	programmed cell death 4	0.012
Irs2	insulin receptor substrate 2	0.012
Zfp266	zinc finger protein 266	0.012
Dcaf13	DDB1 and CUL4 associated factor 13	0.012
Bcl6	B-cell leukemia/lymphoma 6	0.012
Mbtd1	mbt domain containing 1	0.012
Helz	helicase with zinc finger domain	0.011
Gtf2a1	general transcription factor II A, 1	0.011
Nxf1	nuclear RNA export factor 1 homolog (S. cerevisiae)	0.011
Celf1	CUGBP, Elav-like family member 1	0.011	Zebrafish
Smad1	MAD homolog 1 (Drosophila)	0.011
Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.011
Stk4	serine/threonine kinase 4	0.011
Cramp1l	Crm, cramped-like (Drosophila)	0.011
Anapc1	anaphase promoting complex subunit 1	0.011
Rspry1	ring finger and SPRY domain containing 1	0.011
Zfp263	zinc finger protein 263	0.011
Sesn3	sestrin 3	0.011
Pdcd10	programmed cell death 10	0.011
Fam188a	family with sequence similarity 188, member A	0.011
Nup153	nucleoporin 153	0.011
Rnf126	ring finger protein 126	0.011
Zfp280c	zinc finger protein 280C	0.011
Snrpa1	small nuclear ribonucleoprotein polypeptide A'	0.011
Tnrc6a	trinucleotide repeat containing 6a	0.011
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.011
Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	0.011
Fas	Fas (TNF receptor superfamily member 6)	0.011
Nupl1	nucleoporin like 1	0.011
Ssh2	slingshot homolog 2 (Drosophila)	0.011
Bcas2	breast carcinoma amplified sequence 2	0.011
Rps20	ribosomal protein S20	0.011
Ppp1r14b	protein phosphatase 1, regulatory (inhibitor) subunit 14B	0.011
Timm9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.011
Ankrd10	ankyrin repeat domain 10	0.011
Ltbr	lymphotoxin B receptor	0.011
D030056L22Rik	RIKEN cDNA D030056L22 gene	0.011
Pknox1	Pbx/knotted 1 homeobox	0.010
Srpk1	serine/arginine-rich protein specific kinase 1	0.010
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.010
Stx16	syntaxin 16	0.010
Gtf2b	general transcription factor IIB	0.010
Ncbp1	nuclear cap binding protein subunit 1	0.010
Mcmbp	MCM (minichromosome maintenance deficient) binding protein	0.010
Set	SET nuclear oncogene	0.010
Ogfr	opioid growth factor receptor	0.010
Xpot	exportin, tRNA (nuclear export receptor for tRNAs)	0.010
Ccnt1	cyclin T1	0.010
Msl1	male-specific lethal 1 homolog (Drosophila)	0.010
Prkd3	protein kinase D3	0.010
Blnk	B-cell linker	0.010
Eif3a	eukaryotic translation initiation factor 3, subunit A	0.010
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.010
Cnot3	CCR4-NOT transcription complex, subunit 3	0.010
Ireb2	iron responsive element binding protein 2	0.010
Khsrp	KH-type splicing regulatory protein	0.010
U2af1	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1	0.010
Cpsf3	cleavage and polyadenylation specificity factor 3	0.010
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.010
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.010
Fbxl20	F-box and leucine-rich repeat protein 20	0.010
Eif4a3	eukaryotic translation initiation factor 4A3	0.010	Human
Rad17	RAD17 homolog (S. pombe)	0.010
Whsc1	Wolf-Hirschhorn syndrome candidate 1 (human)	0.010
Cdk12	cyclin-dependent kinase 12	0.010
Magohb	mago-nashi homolog B (Drosophila)	0.010
Spag9	sperm associated antigen 9	0.010
2310036O22Rik	RIKEN cDNA 2310036O22 gene	0.010
Drosha	drosha, ribonuclease type III	0.010
Htt	huntingtin	0.010
Vhl	von Hippel-Lindau tumor suppressor	0.010