IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

positive regulation of striated muscle contraction

GO:0045989

Any process that activates or increases the frequency, rate or extent of striated muscle contraction.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of striated muscle contraction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of striated muscle contraction" (in gray)

Name	Description	Probability	Func Analog Organism
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.416
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.393
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.315
Hsph1	heat shock 105kDa/110kDa protein 1	0.238
Hspa8	heat shock protein 8	0.216
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.190
Pvalb	parvalbumin	0.085
Hspa5	heat shock protein 5	0.081
Itgb1bp2	integrin beta 1 binding protein 2	0.079
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.075
Ednrb	endothelin receptor type B	0.074
Tmem146	transmembrane protein 146	0.069
Scn1a	sodium channel, voltage-gated, type I, alpha	0.069
Actn2	actinin alpha 2	0.064
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.062
Casq2	calsequestrin 2	0.060
Sparcl1	SPARC-like 1	0.055
Cox8b	cytochrome c oxidase, subunit VIIIb	0.055
Cdh13	cadherin 13	0.054
Scn5a	sodium channel, voltage-gated, type V, alpha	0.053
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.052
Vamp2	vesicle-associated membrane protein 2	0.050
Tmprss6	transmembrane serine protease 6	0.049
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.048
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.046
Hbb-b2	hemoglobin, beta adult minor chain	0.045
Cacybp	calcyclin binding protein	0.044
Ptprb	protein tyrosine phosphatase, receptor type, B	0.044
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.043
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.041
Iqcb1	IQ calmodulin-binding motif containing 1	0.040
Ldb3	LIM domain binding 3	0.039
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.038
Hspd1	heat shock protein 1 (chaperonin)	0.037
Darc	Duffy blood group, chemokine receptor	0.036
Casq1	calsequestrin 1	0.035
Ank1	ankyrin 1, erythroid	0.035
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.034
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.034
Prkcb	protein kinase C, beta	0.033
Fkbp1b	FK506 binding protein 1b	0.033
Cckbr	cholecystokinin B receptor	0.032
Ahi1	Abelson helper integration site 1	0.032
Pygm	muscle glycogen phosphorylase	0.032
Actc1	actin, alpha, cardiac muscle 1	0.031
Nkx6-3	NK6 homeobox 3	0.031
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.031
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.030
Tnnc2	troponin C2, fast	0.030
Akt1	thymoma viral proto-oncogene 1	0.030
Rgs7	regulator of G protein signaling 7	0.030
Adra1b	adrenergic receptor, alpha 1b	0.030
Bzw1	basic leucine zipper and W2 domains 1	0.030
Eed	embryonic ectoderm development	0.029
Car2	carbonic anhydrase 2	0.029
Srpk3	serine/arginine-rich protein specific kinase 3	0.028
Nrap	nebulin-related anchoring protein	0.028
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.028
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.028
Trp63	transformation related protein 63	0.027
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.027
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.026
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.026
Kcne2	potassium voltage-gated channel, Isk-related subfamily, gene 2	0.026
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.025
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.025
Cntn1	contactin 1	0.024
Cul9	cullin 9	0.024
Fam105a	family with sequence similarity 105, member A	0.024
Tnnt3	troponin T3, skeletal, fast	0.023
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.023
F3	coagulation factor III	0.023
Sncb	synuclein, beta	0.023
Plp1	proteolipid protein (myelin) 1	0.023
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.023
Htt	huntingtin	0.023
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.023
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.023
Clstn1	calsyntenin 1	0.023
Ckmt2	creatine kinase, mitochondrial 2	0.022
Myom2	myomesin 2	0.022
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.022
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.022
Cyr61	cysteine rich protein 61	0.022
Cadm3	cell adhesion molecule 3	0.022
Timp3	tissue inhibitor of metalloproteinase 3	0.021
Frmd5	FERM domain containing 5	0.021
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.021
Hspa4l	heat shock protein 4 like	0.021
Plin4	perilipin 4	0.021
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.021
Lama2	laminin, alpha 2	0.020
Zc3h15	zinc finger CCCH-type containing 15	0.020
Nefm	neurofilament, medium polypeptide	0.020
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.020
Tnni2	troponin I, skeletal, fast 2	0.020
Myom1	myomesin 1	0.019
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.019
Rasa3	RAS p21 protein activator 3	0.019
Astn1	astrotactin 1	0.019
Ptpro	protein tyrosine phosphatase, receptor type, O	0.019
Hpca	hippocalcin	0.019
Sdpr	serum deprivation response	0.019
Tmprss13	transmembrane protease, serine 13	0.019
Col19a1	collagen, type XIX, alpha 1	0.019
Hbb-b1	hemoglobin, beta adult major chain	0.018
Nop58	NOP58 ribonucleoprotein homolog (yeast)	0.018
Tcap	titin-cap	0.018
Ptprm	protein tyrosine phosphatase, receptor type, M	0.018
Nsg2	neuron specific gene family member 2	0.018
Prkcc	protein kinase C, gamma	0.018
Errfi1	ERBB receptor feedback inhibitor 1	0.018
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.018
Hrc	histidine rich calcium binding protein	0.018
Nsf	N-ethylmaleimide sensitive fusion protein	0.018
Ntsr2	neurotensin receptor 2	0.018
Pcp4	Purkinje cell protein 4	0.018
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.018
Tubb2a	tubulin, beta 2A	0.018
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.017
Gpr37l1	G protein-coupled receptor 37-like 1	0.017
St6galnac5	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	0.017
Npy1r	neuropeptide Y receptor Y1	0.017
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.017
Gja1	gap junction protein, alpha 1	0.017
Acta1	actin, alpha 1, skeletal muscle	0.017
Arrb2	arrestin, beta 2	0.016
Limch1	LIM and calponin homology domains 1	0.016
Phkg1	phosphorylase kinase gamma 1	0.016
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.016
Hrh2	histamine receptor H2	0.016
Fgfrl1	fibroblast growth factor receptor-like 1	0.016
Myl1	myosin, light polypeptide 1	0.016
Kap	kidney androgen regulated protein	0.016
Fgf13	fibroblast growth factor 13	0.016
Twf2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.016
Ttn	titin	0.016
Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1	0.016
Lpar1	lysophosphatidic acid receptor 1	0.016
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.015
Actg1	actin, gamma, cytoplasmic 1	0.015
Matk	megakaryocyte-associated tyrosine kinase	0.015
Cd83	CD83 antigen	0.015
Ckm	creatine kinase, muscle	0.015
Cel	carboxyl ester lipase	0.015
Cpne6	copine VI	0.015
Mbp	myelin basic protein	0.015
Dusp1	dual specificity phosphatase 1	0.015
Ahsa2	AHA1, activator of heat shock protein ATPase homolog 2 (yeast)	0.015
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.015
Nefl	neurofilament, light polypeptide	0.015
Camk4	calcium/calmodulin-dependent protein kinase IV	0.015
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.015
Snap25	synaptosomal-associated protein 25	0.015
Prrx1	paired related homeobox 1	0.015
Coro1a	coronin, actin binding protein 1A	0.015
Canx	calnexin	0.015
Chl1	cell adhesion molecule with homology to L1CAM	0.015
Stk32c	serine/threonine kinase 32C	0.015
Scg3	secretogranin III	0.014
Rgs4	regulator of G-protein signaling 4	0.014	Mouse
Morf4l2	mortality factor 4 like 2	0.014
Syt1	synaptotagmin I	0.014
Sgk1	serum/glucocorticoid regulated kinase 1	0.014
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.014
Ncan	neurocan	0.014
Prnp	prion protein	0.014
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.014
Plcb1	phospholipase C, beta 1	0.014
Cct6a	chaperonin containing Tcp1, subunit 6a (zeta)	0.014
Neurod2	neurogenic differentiation 2	0.014
Ccdc109b	coiled-coil domain containing 109B	0.014
Myoz1	myozenin 1	0.014
Fgf1	fibroblast growth factor 1	0.014
Calm1	calmodulin 1	0.014
Stac3	SH3 and cysteine rich domain 3	0.014
Cd200	CD200 antigen	0.014
Lamp3	lysosomal-associated membrane protein 3	0.014
Ly86	lymphocyte antigen 86	0.014
Aif1	allograft inflammatory factor 1	0.014
Gpx6	glutathione peroxidase 6	0.013
Prox1	prospero-related homeobox 1	0.013
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.013
Gfap	glial fibrillary acidic protein	0.013
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.013
Rtn2	reticulon 2 (Z-band associated protein)	0.013
Mcoln1	mucolipin 1	0.013
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.013
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.013
Fhod3	formin homology 2 domain containing 3	0.013
Emcn	endomucin	0.013
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.013
Fosb	FBJ osteosarcoma oncogene B	0.013
Dynll1	dynein light chain LC8-type 1	0.013
Mef2c	myocyte enhancer factor 2C	0.013
Thy1	thymus cell antigen 1, theta	0.013
Npr3	natriuretic peptide receptor 3	0.013
Adcy2	adenylate cyclase 2	0.013
Ryr1	ryanodine receptor 1, skeletal muscle	0.013	Mouse
Col17a1	collagen, type XVII, alpha 1	0.013
Ogn	osteoglycin	0.013
Capn3	calpain 3	0.013
Egr2	early growth response 2	0.013
Rab5c	RAB5C, member RAS oncogene family	0.013
Dtna	dystrobrevin alpha	0.013
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.013
Olfr16	olfactory receptor 16	0.013
Ppp1r1a	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.013
Gal	galanin	0.013
Bex6	brain expressed gene 6	0.012
Sorbs1	sorbin and SH3 domain containing 1	0.012
St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.012
Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	0.012
Scn10a	sodium channel, voltage-gated, type X, alpha	0.012
Tuba1a	tubulin, alpha 1A	0.012
Lxn	latexin	0.012
Mtap2	microtubule-associated protein 2	0.012
Spna2	spectrin alpha 2	0.012
Rgs6	regulator of G-protein signaling 6	0.012
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.012
Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.012
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.012
Coch	coagulation factor C homolog (Limulus polyphemus)	0.012
Dtx1	deltex 1 homolog (Drosophila)	0.012
Fezf2	Fez family zinc finger 2	0.012
Dio2	deiodinase, iodothyronine, type II	0.012
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.012
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.012
Gm6788	predicted gene 6788	0.012
Dennd4b	DENN/MADD domain containing 4B	0.012
Lrrk2	leucine-rich repeat kinase 2	0.012
Gpm6b	glycoprotein m6b	0.012
Scrg1	scrapie responsive gene 1	0.012
Actn1	actinin, alpha 1	0.012
Cst9	cystatin 9	0.012
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.012
Gh	growth hormone	0.012
Pgam2	phosphoglycerate mutase 2	0.012
Rasd1	RAS, dexamethasone-induced 1	0.012
Pdlim3	PDZ and LIM domain 3	0.012
Timp4	tissue inhibitor of metalloproteinase 4	0.012
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.012
Cd33	CD33 antigen	0.012
Gli2	GLI-Kruppel family member GLI2	0.012
Fgfr3	fibroblast growth factor receptor 3	0.012
Sncg	synuclein, gamma	0.012
L1cam	L1 cell adhesion molecule	0.012
Vldlr	very low density lipoprotein receptor	0.012
Doc2b	double C2, beta	0.012
Rtn1	reticulon 1	0.012
Klf1	Kruppel-like factor 1 (erythroid)	0.012
Oxt	oxytocin	0.012
Clstn3	calsyntenin 3	0.012
Lmod3	leiomodin 3 (fetal)	0.012
Ptgds	prostaglandin D2 synthase (brain)	0.012
Evl	Ena-vasodilator stimulated phosphoprotein	0.012
Sh3bgr	SH3-binding domain glutamic acid-rich protein	0.012
Fam65b	family with sequence similarity 65, member B	0.011
Ttr	transthyretin	0.011
Hhatl	hedgehog acyltransferase-like	0.011
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.011
Hspa9	heat shock protein 9	0.011
Art3	ADP-ribosyltransferase 3	0.011
Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1	0.011
Alpk3	alpha-kinase 3	0.011
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.011
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.011
Padi2	peptidyl arginine deiminase, type II	0.011
Rab3a	RAB3A, member RAS oncogene family	0.011
Rpgrip1l	Rpgrip1-like	0.011
Rhoj	ras homolog gene family, member J	0.011
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.011
Samd4	sterile alpha motif domain containing 4	0.011
Tmem182	transmembrane protein 182	0.011
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.011
Mpped1	metallophosphoesterase domain containing 1	0.011
Zic1	zinc finger protein of the cerebellum 1	0.011
Kdm5a	lysine (K)-specific demethylase 5A	0.011
Parm1	prostate androgen-regulated mucin-like protein 1	0.011
Cotl1	coactosin-like 1 (Dictyostelium)	0.011
Hspb3	heat shock protein 3	0.011
Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	0.011
Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	0.011
Cryab	crystallin, alpha B	0.011
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.011
Dck	deoxycytidine kinase	0.011
Rps6kl1	ribosomal protein S6 kinase-like 1	0.011
Laptm5	lysosomal-associated protein transmembrane 5	0.011
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.011
Adam23	a disintegrin and metallopeptidase domain 23	0.011
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.011
Ccl20	chemokine (C-C motif) ligand 20	0.011
Anxa3	annexin A3	0.011
Nrsn1	neurensin 1	0.011
Rarb	retinoic acid receptor, beta	0.011
Nrgn	neurogranin	0.011
Trpc3	transient receptor potential cation channel, subfamily C, member 3	0.011
Cplx3	complexin 3	0.011
Syn2	synapsin II	0.011
Fxyd1	FXYD domain-containing ion transport regulator 1	0.011
Klf4	Kruppel-like factor 4 (gut)	0.011
Cntn3	contactin 3	0.011
Wwtr1	WW domain containing transcription regulator 1	0.010
Slc18a1	solute carrier family 18 (vesicular monoamine), member 1	0.010
Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	0.010
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.010
Rgs5	regulator of G-protein signaling 5	0.010	Mouse
Flt1	FMS-like tyrosine kinase 1	0.010
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.010
Stmn2	stathmin-like 2	0.010
Arrb1	arrestin, beta 1	0.010
Gpr83	G protein-coupled receptor 83	0.010
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.010
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.010
Snap91	synaptosomal-associated protein 91	0.010
Zfpm2	zinc finger protein, multitype 2	0.010
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.010
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.010
Svop	SV2 related protein	0.010
Oprl1	opioid receptor-like 1	0.010
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.010
Fos	FBJ osteosarcoma oncogene	0.010
Spink8	serine peptidase inhibitor, Kazal type 8	0.010
Penk	preproenkephalin	0.010
Ryr3	ryanodine receptor 3	0.010	Mouse
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.010
Olfm1	olfactomedin 1	0.010
Bsnd	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.010
Cct2	chaperonin containing Tcp1, subunit 2 (beta)	0.010
Rasgrp1	RAS guanyl releasing protein 1	0.010
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.010
Dlg2	discs, large homolog 2 (Drosophila)	0.010
Mb	myoglobin	0.010
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.010
Stx1a	syntaxin 1A (brain)	0.010
Tspan2	tetraspanin 2	0.010
Trim54	tripartite motif-containing 54	0.010
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.010