IMP: Integrative Multi-species Prediction

Mus musculus

59 genes annotated in mouse

response to decreased oxygen levels

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to decreased oxygen levels"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to decreased oxygen levels" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	0.999
Vegfa	vascular endothelial growth factor A	0.997	Human
Trp53	transformation related protein 53	0.995	Human Zebrafish Worm
Tgfbr2	transforming growth factor, beta receptor II	0.988	Rat
Nos1	nitric oxide synthase 1, neuronal	0.976	Human Mouse Rat
Nos3	nitric oxide synthase 3, endothelial cell	0.958	Mouse Rat
Csf1	colony stimulating factor 1 (macrophage)	0.957
Lyz2	lysozyme 2	0.924
Mmp9	matrix metallopeptidase 9	0.911	Mouse Rat
Insr	insulin receptor	0.888	Fly
Ldb3	LIM domain binding 3	0.802
Pparg	peroxisome proliferator activated receptor gamma	0.799	Mouse
Clock	circadian locomotor output cycles kaput	0.793
Egfl7	EGF-like domain 7	0.770
Fbn1	fibrillin 1	0.752
Thbs1	thrombospondin 1	0.737
Hbb-b1	hemoglobin, beta adult major chain	0.647
Lepr	leptin receptor	0.633
Ece1	endothelin converting enzyme 1	0.625	Rat
Ptgs2	prostaglandin-endoperoxide synthase 2	0.615	Human
Tgfb1	transforming growth factor, beta 1	0.597	Rat
Epas1	endothelial PAS domain protein 1	0.590
Acvrl1	activin A receptor, type II-like 1	0.589
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.557	Human
Cav1	caveolin 1, caveolae protein	0.547
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.544
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.520
Rb1	retinoblastoma 1	0.505
Emx1	empty spiracles homolog 1 (Drosophila)	0.499
Tgfb2	transforming growth factor, beta 2	0.495	Human
Notch2	Notch gene homolog 2 (Drosophila)	0.492	Mouse
Cd44	CD44 antigen	0.479
Gata6	GATA binding protein 6	0.472	Human
Skil	SKI-like	0.463
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.460
Il6st	interleukin 6 signal transducer	0.460
Ghr	growth hormone receptor	0.458
Tpi1	triosephosphate isomerase 1	0.431
Neurl1a	neuralized homolog 1A (Drosophila)	0.411
Ctnnb1	catenin (cadherin associated protein), beta 1	0.407
Lep	leptin	0.403
Bdkrb2	bradykinin receptor, beta 2	0.400
Plau	plasminogen activator, urokinase	0.387
Ccl2	chemokine (C-C motif) ligand 2	0.383
Hbb-b2	hemoglobin, beta adult minor chain	0.374
Ahr	aryl-hydrocarbon receptor	0.368
Gata4	GATA binding protein 4	0.368
Lox	lysyl oxidase	0.368
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.367	Zebrafish Rat
Edn1	endothelin 1	0.364
Vhl	von Hippel-Lindau tumor suppressor	0.346	Human Worm Fly
Ep300	E1A binding protein p300	0.334	Human
Onecut1	one cut domain, family member 1	0.331
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.327	Mouse
Kit	kit oncogene	0.312	Mouse
Gpi1	glucose phosphate isomerase 1	0.309
Dll1	delta-like 1 (Drosophila)	0.309
Vdr	vitamin D receptor	0.307	Mouse
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.303	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.296
Prkcc	protein kinase C, gamma	0.294
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.293
Chrnb4	cholinergic receptor, nicotinic, beta polypeptide 4	0.288	Mouse
Nos2	nitric oxide synthase 2, inducible	0.286
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.285
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.280
Smad3	MAD homolog 3 (Drosophila)	0.270	Human
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.265
Stat3	signal transducer and activator of transcription 3	0.261
Wnt6	wingless-related MMTV integration site 6	0.256
Hif1a	hypoxia inducible factor 1, alpha subunit	0.253
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.251
Fgf8	fibroblast growth factor 8	0.250
Apoa1	apolipoprotein A-I	0.247
Col1a1	collagen, type I, alpha 1	0.246
Fgfr2	fibroblast growth factor receptor 2	0.242
Pax6	paired box gene 6	0.240
Loxl1	lysyl oxidase-like 1	0.239
Flt1	FMS-like tyrosine kinase 1	0.239
Plg	plasminogen	0.235	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.231
Pgk1	phosphoglycerate kinase 1	0.230
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.228	Human
Sox9	SRY-box containing gene 9	0.228
Myod1	myogenic differentiation 1	0.226
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.225
Cryab	crystallin, alpha B	0.222
Selp	selectin, platelet	0.216
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.215
Ar	androgen receptor	0.213
Foxo1	forkhead box O1	0.211
Gnrh1	gonadotropin releasing hormone 1	0.208
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.206
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.204
Col4a3	collagen, type IV, alpha 3	0.203
Pdgfb	platelet derived growth factor, B polypeptide	0.203
Kl	klotho	0.201
Agtr1a	angiotensin II receptor, type 1a	0.194
Meox1	mesenchyme homeobox 1	0.192
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.188	Rat
Gm5506	predicted gene 5506	0.188
Tsc1	tuberous sclerosis 1	0.186	Fly
Ifngr1	interferon gamma receptor 1	0.183
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.180
Apc	adenomatosis polyposis coli	0.172
Apoe	apolipoprotein E	0.172
Pkd1	polycystic kidney disease 1 homolog	0.172
Htra3	HtrA serine peptidase 3	0.172
Gdnf	glial cell line derived neurotrophic factor	0.170
Cyld	cylindromatosis (turban tumor syndrome)	0.169
Notch4	Notch gene homolog 4 (Drosophila)	0.167	Mouse
Gh	growth hormone	0.166	Mouse
Tgfbr1	transforming growth factor, beta receptor I	0.166	Rat
Col4a1	collagen, type IV, alpha 1	0.165
Spry4	sprouty homolog 4 (Drosophila)	0.164
Prlr	prolactin receptor	0.161
Nodal	nodal	0.158
Smad1	MAD homolog 1 (Drosophila)	0.157
Prkce	protein kinase C, epsilon	0.156
Notch1	Notch gene homolog 1 (Drosophila)	0.155
Cd151	CD151 antigen	0.154
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.152
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.150
Hif3a	hypoxia inducible factor 3, alpha subunit	0.148
Pkm2	pyruvate kinase, muscle	0.146
Ldha	lactate dehydrogenase A	0.142	Zebrafish
Tcfap2a	transcription factor AP-2, alpha	0.142
Per2	period homolog 2 (Drosophila)	0.141
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.141
Tgm2	transglutaminase 2, C polypeptide	0.140
Tlr4	toll-like receptor 4	0.137	Rat
Il18	interleukin 18	0.137
Fgf23	fibroblast growth factor 23	0.137
Prrx1	paired related homeobox 1	0.134
Alx3	aristaless-like homeobox 3	0.133
Dok1	docking protein 1	0.131
Irs2	insulin receptor substrate 2	0.130	Fly
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.130
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.129
Stat6	signal transducer and activator of transcription 6	0.127
Upk3b	uroplakin 3B	0.126
Egr1	early growth response 1	0.125
Cyr61	cysteine rich protein 61	0.124
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.122
Eng	endoglin	0.121	Human
Tsc2	tuberous sclerosis 2	0.121
F2r	coagulation factor II (thrombin) receptor	0.121
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.121
Bcl2	B-cell leukemia/lymphoma 2	0.119
Ptprb	protein tyrosine phosphatase, receptor type, B	0.119
Sfn	stratifin	0.119
Egln1	EGL nine homolog 1 (C. elegans)	0.119	Human Rat Worm Fly
Npc1	Niemann Pick type C1	0.118
Ren1	renin 1 structural	0.118
Ltbp3	latent transforming growth factor beta binding protein 3	0.117
Kdr	kinase insert domain protein receptor	0.117	Mouse
Sox17	SRY-box containing gene 17	0.117
Tcf21	transcription factor 21	0.116
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.114	Human
Hand2	heart and neural crest derivatives expressed transcript 2	0.114	Mouse
Tnf	tumor necrosis factor	0.113	Rat
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.113
Glra1	glycine receptor, alpha 1 subunit	0.113
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.111
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.111
Hrh1	histamine receptor H1	0.111
Rxra	retinoid X receptor alpha	0.111
Gypa	glycophorin A	0.110
Psen1	presenilin 1	0.110
Mdm2	transformed mouse 3T3 cell double minute 2	0.110	Human
Hdac1	histone deacetylase 1	0.109
Rbl1	retinoblastoma-like 1 (p107)	0.108
Otp	orthopedia homolog (Drosophila)	0.105
Stat5a	signal transducer and activator of transcription 5A	0.105
Gata1	GATA binding protein 1	0.104
Pax3	paired box gene 3	0.104
Kcnk3	potassium channel, subfamily K, member 3	0.102
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.102
Gpr50	G-protein-coupled receptor 50	0.101
Epha2	Eph receptor A2	0.101
Adcy4	adenylate cyclase 4	0.101
Kiss1r	KISS1 receptor	0.101
Galr1	galanin receptor 1	0.100
Esr1	estrogen receptor 1 (alpha)	0.098
Nrp1	neuropilin 1	0.098
Egln3	EGL nine homolog 3 (C. elegans)	0.098	Rat Worm Fly
Cry2	cryptochrome 2 (photolyase-like)	0.096
F2	coagulation factor II	0.095
Grb10	growth factor receptor bound protein 10	0.094
Bhlha15	basic helix-loop-helix family, member a15	0.093	Mouse
Mmp2	matrix metallopeptidase 2	0.093
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.093
Gck	glucokinase	0.092
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.092
Hdac2	histone deacetylase 2	0.092
Ltbp2	latent transforming growth factor beta binding protein 2	0.092
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.091
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.090
Cdh5	cadherin 5	0.090
Fos	FBJ osteosarcoma oncogene	0.090
Hnf4a	hepatic nuclear factor 4, alpha	0.089
Pnpla2	patatin-like phospholipase domain containing 2	0.089
Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	0.088
Epor	erythropoietin receptor	0.087
Guca2b	guanylate cyclase activator 2b (retina)	0.087
Proc	protein C	0.085
Cxcl13	chemokine (C-X-C motif) ligand 13	0.083
Pfkl	phosphofructokinase, liver, B-type	0.082
Tgfbr3	transforming growth factor, beta receptor III	0.082	Rat
Lhx6	LIM homeobox protein 6	0.081
Mkl2	MKL/myocardin-like 2	0.081	Fly
Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)	0.080
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.080
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.079
Kitl	kit ligand	0.079
Hspb1	heat shock protein 1	0.079	Mouse Fly
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.079	Rat
Rint1	RAD50 interactor 1	0.077
Fosb	FBJ osteosarcoma oncogene B	0.077
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.077
Itpr3	inositol 1,4,5-triphosphate receptor 3	0.077	Mouse
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.076
Ikzf1	IKAROS family zinc finger 1	0.075
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.075	Mouse
Amh	anti-Mullerian hormone	0.075
Col4a2	collagen, type IV, alpha 2	0.074
Col6a1	collagen, type VI, alpha 1	0.073
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.073
Bmp8b	bone morphogenetic protein 8b	0.073
Vipr1	vasoactive intestinal peptide receptor 1	0.073
Kiss1	KiSS-1 metastasis-suppressor	0.072
Dusp1	dual specificity phosphatase 1	0.072
Wnt11	wingless-related MMTV integration site 11	0.072
Rara	retinoic acid receptor, alpha	0.071
Foxf1a	forkhead box F1a	0.071
Jag1	jagged 1	0.071
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.071
Ahsg	alpha-2-HS-glycoprotein	0.071
Ptf1a	pancreas specific transcription factor, 1a	0.071	Mouse
Il1r1	interleukin 1 receptor, type I	0.070
Ncoa3	nuclear receptor coactivator 3	0.070
Trfr2	transferrin receptor 2	0.070
Fbxw7	F-box and WD-40 domain protein 7	0.070
Sim1	single-minded homolog 1 (Drosophila)	0.070	Mouse
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.069
E2f1	E2F transcription factor 1	0.069
Eif4a2	eukaryotic translation initiation factor 4A2	0.069
Hic1	hypermethylated in cancer 1	0.068
Lmna	lamin A	0.068	Human
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.068
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.068
Clcnka	chloride channel Ka	0.068
Hsf4	heat shock transcription factor 4	0.068
Wisp2	WNT1 inducible signaling pathway protein 2	0.067
Ppard	peroxisome proliferator activator receptor delta	0.067
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.067
Twist1	twist homolog 1 (Drosophila)	0.067
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.067
Fzd4	frizzled homolog 4 (Drosophila)	0.066
Plat	plasminogen activator, tissue	0.066
Mapkap1	mitogen-activated protein kinase associated protein 1	0.066
Igf2r	insulin-like growth factor 2 receptor	0.065
Nf2	neurofibromatosis 2	0.065
Daxx	Fas death domain-associated protein	0.065
Agtr2	angiotensin II receptor, type 2	0.064
Myc	myelocytomatosis oncogene	0.064
Ager	advanced glycosylation end product-specific receptor	0.064
Mpz	myelin protein zero	0.063
Acvr1	activin A receptor, type 1	0.062
Cry1	cryptochrome 1 (photolyase-like)	0.062
Fgf9	fibroblast growth factor 9	0.062
Vav2	vav 2 oncogene	0.061
Has1	hyaluronan synthase1	0.061
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.061
Smo	smoothened homolog (Drosophila)	0.060
Krt5	keratin 5	0.060
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.060
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.060
Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.059
Ptgir	prostaglandin I receptor (IP)	0.059
Fgfr1	fibroblast growth factor receptor 1	0.059
Socs1	suppressor of cytokine signaling 1	0.059
Axl	AXL receptor tyrosine kinase	0.059
Wnt10b	wingless related MMTV integration site 10b	0.058
Hspd1	heat shock protein 1 (chaperonin)	0.058
Elane	elastase, neutrophil expressed	0.058
Psg19	pregnancy specific glycoprotein 19	0.057
Notch3	Notch gene homolog 3 (Drosophila)	0.057	Mouse
Ccbp2	chemokine binding protein 2	0.057
Per1	period homolog 1 (Drosophila)	0.056
Yap1	yes-associated protein 1	0.056
Ptrf	polymerase I and transcript release factor	0.056
Barx2	BarH-like homeobox 2	0.055
Ephb2	Eph receptor B2	0.055
Mybph	myosin binding protein H	0.055
Chrna9	cholinergic receptor, nicotinic, alpha polypeptide 9	0.055	Mouse
Prdm1	PR domain containing 1, with ZNF domain	0.055
Pthlh	parathyroid hormone-like peptide	0.054
Irf1	interferon regulatory factor 1	0.054
Trp73	transformation related protein 73	0.054	Worm
Huwe1	HECT, UBA and WWE domain containing 1	0.054
Loxl2	lysyl oxidase-like 2	0.053
Npy1r	neuropeptide Y receptor Y1	0.053
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.053
Tln1	talin 1	0.053
Fmo3	flavin containing monooxygenase 3	0.053
Msln	mesothelin	0.053
Popdc3	popeye domain containing 3	0.052
Hhex	hematopoietically expressed homeobox	0.052
Flt4	FMS-like tyrosine kinase 4	0.052	Mouse
Il10	interleukin 10	0.051
Gata2	GATA binding protein 2	0.051
Smad4	MAD homolog 4 (Drosophila)	0.051	Human
Igf1	insulin-like growth factor 1	0.051
Foxa2	forkhead box A2	0.051
Asxl1	additional sex combs like 1 (Drosophila)	0.051
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.050
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.050
Pmp22	peripheral myelin protein 22	0.050
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.050	Mouse
Col13a1	collagen, type XIII, alpha 1	0.050
Nppb	natriuretic peptide type B	0.050
Fgg	fibrinogen gamma chain	0.050
Pgam1	phosphoglycerate mutase 1	0.050
Sult5a1	sulfotransferase family 5A, member 1	0.049
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.049
Grem1	gremlin 1	0.049
Msh2	mutS homolog 2 (E. coli)	0.049
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.049
Spna1	spectrin alpha 1	0.049
Sik3	SIK family kinase 3	0.049
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.049
Ptk2	PTK2 protein tyrosine kinase 2	0.049
Igbp1b	immunoglobulin (CD79A) binding protein 1b	0.049
Col10a1	collagen, type X, alpha 1	0.048
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.048
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.048
Itgb3	integrin beta 3	0.048
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.048
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.047
Gbp5	guanylate binding protein 5	0.047
Pla2r1	phospholipase A2 receptor 1	0.047
Bhlhe40	basic helix-loop-helix family, member e40	0.047
Cd36	CD36 antigen	0.047
Chrna10	cholinergic receptor, nicotinic, alpha polypeptide 10	0.047	Mouse
Sva	seminal vesicle antigen	0.046
Tacr1	tachykinin receptor 1	0.046
Mn1	meningioma 1	0.046
Slc6a18	solute carrier family 6 (neurotransmitter transporter), member 18	0.046
Flnc	filamin C, gamma	0.046
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.046
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.046
Apob	apolipoprotein B	0.046
Psen2	presenilin 2	0.046
Alx4	aristaless-like homeobox 4	0.046
Apom	apolipoprotein M	0.046
Adrb1	adrenergic receptor, beta 1	0.046
Hand1	heart and neural crest derivatives expressed transcript 1	0.045	Mouse
Ikbkb	inhibitor of kappaB kinase beta	0.045
Bnip3	BCL2/adenovirus E1B interacting protein 3	0.045	Human
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.045
Agpat1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.045
Hrh2	histamine receptor H2	0.045
Dhh	desert hedgehog	0.045
Rax	retina and anterior neural fold homeobox	0.045
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.045
Junb	Jun-B oncogene	0.044
Cd14	CD14 antigen	0.044
Trim47	tripartite motif-containing 47	0.044
Cryga	crystallin, gamma A	0.044
Stab1	stabilin 1	0.044
Pzp	pregnancy zone protein	0.044
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.044
Bag3	BCL2-associated athanogene 3	0.043
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.043
Rhbdf1	rhomboid family 1 (Drosophila)	0.043
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.043
Srebf2	sterol regulatory element binding factor 2	0.043
Sfpi1	SFFV proviral integration 1	0.043
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.043
Oc90	otoconin 90	0.043
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.043
Cxcl12	chemokine (C-X-C motif) ligand 12	0.043
Gja1	gap junction protein, alpha 1	0.043
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.043
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.043
Tert	telomerase reverse transcriptase	0.042
Ins2	insulin II	0.042
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.042
C5ar1	complement component 5a receptor 1	0.042
Inpp5d	inositol polyphosphate-5-phosphatase D	0.042
Fut7	fucosyltransferase 7	0.042
Wnt3a	wingless-related MMTV integration site 3A	0.041
Gdf1	growth differentiation factor 1	0.041	Mouse
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.041
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.041
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.041
Cdx2	caudal type homeobox 2	0.041
Hc	hemolytic complement	0.041
Ang2	angiogenin, ribonuclease A family, member 2	0.041	Human
Fstl1	follistatin-like 1	0.041
Rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.041
Plcg1	phospholipase C, gamma 1	0.041
Vasn	vasorin	0.041
Lrp5	low density lipoprotein receptor-related protein 5	0.041
Fstl3	follistatin-like 3	0.041
Bgn	biglycan	0.041
Elk3	ELK3, member of ETS oncogene family	0.040
Uqcrc1	ubiquinol-cytochrome c reductase core protein 1	0.040
Myh9	myosin, heavy polypeptide 9, non-muscle	0.040
Kif11	kinesin family member 11	0.040
Gip	gastric inhibitory polypeptide	0.040
Nkx3-2	NK3 homeobox 2	0.040
Ptch1	patched homolog 1	0.040
Icam1	intercellular adhesion molecule 1	0.040	Rat
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.040
1300001I01Rik	RIKEN cDNA 1300001I01 gene	0.040
Ltb	lymphotoxin B	0.040
Arx	aristaless related homeobox	0.040
Gpr33	G protein-coupled receptor 33	0.040
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.039
Ect2	ect2 oncogene	0.039
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.039
Insm1	insulinoma-associated 1	0.039
Amdhd1	amidohydrolase domain containing 1	0.039
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.039
Sox18	SRY-box containing gene 18	0.039
Egfr	epidermal growth factor receptor	0.039
Tmem204	transmembrane protein 204	0.039
Hgfac	hepatocyte growth factor activator	0.039	Mouse
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.039
Prc1	protein regulator of cytokinesis 1	0.039
Sycn	syncollin	0.039
Uts2r	urotensin 2 receptor	0.039
Mrpl4	mitochondrial ribosomal protein L4	0.039
Ecm1	extracellular matrix protein 1	0.039
Lif	leukemia inhibitory factor	0.039
Clcn1	chloride channel 1	0.039
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.039	Rat
Sct	secretin	0.039
Gdf15	growth differentiation factor 15	0.039
Foxd4	forkhead box D4	0.038
Dab1	disabled homolog 1 (Drosophila)	0.038
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.038	Mouse
Bsg	basigin	0.038
Defa-rs12	defensin, alpha, related sequence 12	0.038
Timp1	tissue inhibitor of metalloproteinase 1	0.038
Fgf15	fibroblast growth factor 15	0.038
Slc2a1	solute carrier family 2 (facilitated glucose transporter), member 1	0.038
C1ql3	C1q-like 3	0.038
Casp3	caspase 3	0.038	Mouse
Ctsk	cathepsin K	0.038
Slc25a11	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11	0.038
Lag3	lymphocyte-activation gene 3	0.038
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.038
Rictor	RPTOR independent companion of MTOR, complex 2	0.037
Gjb1	gap junction protein, beta 1	0.037
Prph2	peripherin 2	0.037
Irs1	insulin receptor substrate 1	0.037	Fly
Adora3	adenosine A3 receptor	0.037
Ache	acetylcholinesterase	0.037
Fndc7	fibronectin type III domain containing 7	0.037
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.037
Rbp2	retinol binding protein 2, cellular	0.037
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.036
Mybpc3	myosin binding protein C, cardiac	0.036
Mfng	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.036
Gdf3	growth differentiation factor 3	0.036	Mouse
Mrgprf	MAS-related GPR, member F	0.036
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.036
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.036
H1foo	H1 histone family, member O, oocyte-specific	0.036
Dmbx1	diencephalon/mesencephalon homeobox 1	0.036
Tbx1	T-box 1	0.036
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.036	Rat
Edar	ectodysplasin-A receptor	0.036
C3ar1	complement component 3a receptor 1	0.036
Neurog3	neurogenin 3	0.036	Mouse
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.036
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.036
Sdsl	serine dehydratase-like	0.035
Crebbp	CREB binding protein	0.035
Krt17	keratin 17	0.035
Edn2	endothelin 2	0.035	Mouse
Krt20	keratin 20	0.035
Arnt	aryl hydrocarbon receptor nuclear translocator	0.035
Pigr	polymeric immunoglobulin receptor	0.035
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.035
Timp3	tissue inhibitor of metalloproteinase 3	0.035
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.035
Ank1	ankyrin 1, erythroid	0.035
Plvap	plasmalemma vesicle associated protein	0.035
Xpa	xeroderma pigmentosum, complementation group A	0.035
Plcb1	phospholipase C, beta 1	0.035
Gmnn	geminin	0.035
Gp9	glycoprotein 9 (platelet)	0.035
Rem1	rad and gem related GTP binding protein 1	0.035
Stc2	stanniocalcin 2	0.035
Runx2	runt related transcription factor 2	0.035
Casp12	caspase 12	0.034	Mouse
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.034
Scrg1	scrapie responsive gene 1	0.034
Insm2	insulinoma-associated 2	0.034
Fgf4	fibroblast growth factor 4	0.034
Mdm4	transformed mouse 3T3 cell double minute 4	0.034	Human
Atxn1	ataxin 1	0.034
Per3	period homolog 3 (Drosophila)	0.034
Sgol2	shugoshin-like 2 (S. pombe)	0.034
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.034
Spp1	secreted phosphoprotein 1	0.034
Ereg	epiregulin	0.034
Prl	prolactin	0.034	Mouse
S1pr3	sphingosine-1-phosphate receptor 3	0.034
Fam83f	family with sequence similarity 83, member F	0.033
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.033
Gzmf	granzyme F	0.033
Fgf22	fibroblast growth factor 22	0.033
Inhbc	inhibin beta-C	0.033
Ikbkg	inhibitor of kappaB kinase gamma	0.033
Grm1	glutamate receptor, metabotropic 1	0.033
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.033	Worm
Sin3a	transcriptional regulator, SIN3A (yeast)	0.033
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.033
Canx	calnexin	0.033
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.033
Saa4	serum amyloid A 4	0.033
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.033
Ch25h	cholesterol 25-hydroxylase	0.033
Hlx	H2.0-like homeobox	0.033
Syt8	synaptotagmin VIII	0.033
Epx	eosinophil peroxidase	0.033
Plxnd1	plexin D1	0.033
Thbd	thrombomodulin	0.033
Mixl1	Mix1 homeobox-like 1 (Xenopus laevis)	0.033
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.033
Reg3a	regenerating islet-derived 3 alpha	0.032
Lhx9	LIM homeobox protein 9	0.032
Gckr	glucokinase regulatory protein	0.032
Cryba1	crystallin, beta A1	0.032
Cplx2	complexin 2	0.032
Pgf	placental growth factor	0.032
Mark4	MAP/microtubule affinity-regulating kinase 4	0.032
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.032	Mouse
Foxp3	forkhead box P3	0.032
Myoc	myocilin	0.032
Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	0.032
P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	0.032
Robo4	roundabout homolog 4 (Drosophila)	0.032
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.032
Prodh2	proline dehydrogenase (oxidase) 2	0.032
Cdk1	cyclin-dependent kinase 1	0.032
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.032
Srpk3	serine/arginine-rich protein specific kinase 3	0.032
Hoxb9	homeobox B9	0.031
Calr	calreticulin	0.031
Ppp5c	protein phosphatase 5, catalytic subunit	0.031
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.031
Smad5	MAD homolog 5 (Drosophila)	0.031
Agrp	agouti related protein	0.031
S1pr2	sphingosine-1-phosphate receptor 2	0.031
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.031
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.031
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.031	Mouse
Gabrq	gamma-aminobutyric acid (GABA) A receptor, subunit theta	0.031
Hdac7	histone deacetylase 7	0.031
Pitx3	paired-like homeodomain transcription factor 3	0.031
Kif17	kinesin family member 17	0.031
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.031
Krt6a	keratin 6A	0.031
P2rx6	purinergic receptor P2X, ligand-gated ion channel, 6	0.031
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.031	Rat
Atoh1	atonal homolog 1 (Drosophila)	0.031	Mouse
Adrb3	adrenergic receptor, beta 3	0.031
Grap2	GRB2-related adaptor protein 2	0.031
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.031
Ccr1	chemokine (C-C motif) receptor 1	0.031
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.031
A4galt	alpha 1,4-galactosyltransferase	0.031
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.031
Stc1	stanniocalcin 1	0.031	Rat
Wisp1	WNT1 inducible signaling pathway protein 1	0.031
Il1rn	interleukin 1 receptor antagonist	0.031
Sspo	SCO-spondin	0.031
Ina	internexin neuronal intermediate filament protein, alpha	0.031
Mark2	MAP/microtubule affinity-regulating kinase 2	0.031
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.031
Cks2	CDC28 protein kinase regulatory subunit 2	0.031
Lhx3	LIM homeobox protein 3	0.031
Aloxe3	arachidonate lipoxygenase 3	0.031
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.031
Myo1c	myosin IC	0.031
Il5	interleukin 5	0.031
H2afx	H2A histone family, member X	0.030
Ccna2	cyclin A2	0.030
Igfbp7	insulin-like growth factor binding protein 7	0.030
Mitf	microphthalmia-associated transcription factor	0.030
Dspp	dentin sialophosphoprotein	0.030
Adam17	a disintegrin and metallopeptidase domain 17	0.030	Human
Anln	anillin, actin binding protein	0.030
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.030
Mapk8	mitogen-activated protein kinase 8	0.030
C1ra	complement component 1, r subcomponent A	0.030
Hmgb1	high mobility group box 1	0.030
Tdgf1	teratocarcinoma-derived growth factor 1	0.030
Gpc3	glypican 3	0.030
Nhlh1	nescient helix loop helix 1	0.030	Mouse
Foxc2	forkhead box C2	0.030
Scgb3a1	secretoglobin, family 3A, member 1	0.030
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.030
Bard1	BRCA1 associated RING domain 1	0.030
Sox14	SRY-box containing gene 14	0.030
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.030
Igf2	insulin-like growth factor 2	0.030
Krt25	keratin 25	0.030
Zic3	zinc finger protein of the cerebellum 3	0.030
Esr2	estrogen receptor 2 (beta)	0.030
Akap2	A kinase (PRKA) anchor protein 2	0.030
Srrm4	serine/arginine repetitive matrix 4	0.030
Runx1	runt related transcription factor 1	0.030
Adra2c	adrenergic receptor, alpha 2c	0.030
Mesp1	mesoderm posterior 1	0.030
Lbp	lipopolysaccharide binding protein	0.030
Rora	RAR-related orphan receptor alpha	0.030	Human
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.030
Cntn1	contactin 1	0.030
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.029
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.029	Mouse
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.029
Kif20a	kinesin family member 20A	0.029
Lrrk1	leucine-rich repeat kinase 1	0.029
Prkci	protein kinase C, iota	0.029
Kcnk10	potassium channel, subfamily K, member 10	0.029
Tdo2	tryptophan 2,3-dioxygenase	0.029
Prf1	perforin 1 (pore forming protein)	0.029
Vegfb	vascular endothelial growth factor B	0.029
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.029	Rat
Pdgfa	platelet derived growth factor, alpha	0.029
Bmp2	bone morphogenetic protein 2	0.029
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.029
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.029
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.029
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.029
Lama4	laminin, alpha 4	0.029
Ccl6	chemokine (C-C motif) ligand 6	0.029
Tfrc	transferrin receptor	0.029
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.029
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.029
Dnase1	deoxyribonuclease I	0.029
Rgs9	regulator of G-protein signaling 9	0.029
Cps1	carbamoyl-phosphate synthetase 1	0.029
Prkca	protein kinase C, alpha	0.029	Mouse
Gpr182	G protein-coupled receptor 182	0.028	Rat
Znrf4	zinc and ring finger 4	0.028
Rapsn	receptor-associated protein of the synapse	0.028
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.028
Hsf1	heat shock factor 1	0.028
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.028
Pkd2	polycystic kidney disease 2	0.028
Tat	tyrosine aminotransferase	0.028
Pcdh12	protocadherin 12	0.028
Ms4a4d	membrane-spanning 4-domains, subfamily A, member 4D	0.028
Marveld3	MARVEL (membrane-associating) domain containing 3	0.028
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.028
Bax	BCL2-associated X protein	0.028	Mouse
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.028
Rgs8	regulator of G-protein signaling 8	0.028
Nobox	NOBOX oogenesis homeobox	0.028
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.028
Naa11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	0.028
Utf1	undifferentiated embryonic cell transcription factor 1	0.028
Ccl12	chemokine (C-C motif) ligand 12	0.028
Cldn2	claudin 2	0.028
Gc	group specific component	0.028
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.028
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.028
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.028
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.028
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.028
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.028
Prox1	prospero-related homeobox 1	0.028
Fut4	fucosyltransferase 4	0.028
Lgals2	lectin, galactose-binding, soluble 2	0.028
Tnnc1	troponin C, cardiac/slow skeletal	0.027
Thrb	thyroid hormone receptor beta	0.027
Des	desmin	0.027
Olfr159	olfactory receptor 159	0.027
Sdc3	syndecan 3	0.027
Hspa12b	heat shock protein 12B	0.027
Gjb5	gap junction protein, beta 5	0.027
Wap	whey acidic protein	0.027
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.027
Mcl1	myeloid cell leukemia sequence 1	0.027	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.027
Hip1	huntingtin interacting protein 1	0.027
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.027
Sorbs1	sorbin and SH3 domain containing 1	0.027
Tcap	titin-cap	0.027
Dll4	delta-like 4 (Drosophila)	0.027
Tnnt2	troponin T2, cardiac	0.027
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.027
Tbr1	T-box brain gene 1	0.027
Birc5	baculoviral IAP repeat-containing 5	0.027
Pcdha10	protocadherin alpha 10	0.027
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.027
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.027
Mpl	myeloproliferative leukemia virus oncogene	0.027
Kng1	kininogen 1	0.027
Fam20c	family with sequence similarity 20, member C	0.027
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.027
Ednra	endothelin receptor type A	0.027
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.027
Elf4	E74-like factor 4 (ets domain transcription factor)	0.027
Slc25a48	solute carrier family 25, member 48	0.027
Tlr2	toll-like receptor 2	0.027
Retnlb	resistin like beta	0.026
Ltbp1	latent transforming growth factor beta binding protein 1	0.026
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.026
Dapk2	death-associated protein kinase 2	0.026
Smad2	MAD homolog 2 (Drosophila)	0.026
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.026
Ltc4s	leukotriene C4 synthase	0.026
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.026
Wwox	WW domain-containing oxidoreductase	0.026
Pex5l	peroxisomal biogenesis factor 5-like	0.026
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.026
Ckap2	cytoskeleton associated protein 2	0.026
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.026
Hoxd11	homeobox D11	0.026
Ccnb2	cyclin B2	0.026
Sox7	SRY-box containing gene 7	0.026
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.026	Fly
Smc3	structural maintenace of chromosomes 3	0.026
Plk4	polo-like kinase 4 (Drosophila)	0.026
Sod2	superoxide dismutase 2, mitochondrial	0.026
Gp5	glycoprotein 5 (platelet)	0.026
Syt7	synaptotagmin VII	0.026
Mgp	matrix Gla protein	0.026
Gpr37	G protein-coupled receptor 37	0.026	Mouse
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.026
Pde4b	phosphodiesterase 4B, cAMP specific	0.026
Tm4sf1	transmembrane 4 superfamily member 1	0.026
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.026
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.026
Atf2	activating transcription factor 2	0.026
Vipr2	vasoactive intestinal peptide receptor 2	0.026
4921517D21Rik	RIKEN cDNA 4921517D21 gene	0.026
Il1rl1	interleukin 1 receptor-like 1	0.026
Il17ra	interleukin 17 receptor A	0.026
Twist2	twist homolog 2 (Drosophila)	0.026	Mouse
Sstr3	somatostatin receptor 3	0.026