IMP
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type i interferon production
The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Myd88 | myeloid differentiation primary response gene 88 | 0.998 | ||
| Tlr4 | toll-like receptor 4 | 0.977 | ||
| Gbp7 | guanylate binding protein 7 | 0.950 | Mouse | |
| Stat1 | signal transducer and activator of transcription 1 | 0.917 | ||
| Irf9 | interferon regulatory factor 9 | 0.913 | ||
| Irgm2 | immunity-related GTPase family M member 2 | 0.902 | ||
| Mavs | mitochondrial antiviral signaling protein | 0.881 | ||
| Trim30a | tripartite motif-containing 30A | 0.881 | Mouse | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.880 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.876 | ||
| Gbp2 | guanylate binding protein 2 | 0.869 | Mouse | |
| Ddx60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.844 | ||
| Ikbkg | inhibitor of kappaB kinase gamma | 0.808 | ||
| Trim21 | tripartite motif-containing 21 | 0.757 | ||
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.666 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.657 | ||
| Oasl2 | 2'-5' oligoadenylate synthetase-like 2 | 0.646 | ||
| Aim2 | absent in melanoma 2 | 0.611 | ||
| Casp1 | caspase 1 | 0.595 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.591 | ||
| Rtp4 | receptor transporter protein 4 | 0.576 | ||
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.560 | ||
| Ifih1 | interferon induced with helicase C domain 1 | 0.546 | Human Mouse | |
| Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.438 | ||
| Igtp | interferon gamma induced GTPase | 0.421 | ||
| Cd40 | CD40 antigen | 0.396 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.377 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.374 | ||
| Nmi | N-myc (and STAT) interactor | 0.374 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.343 | ||
| Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.325 | ||
| Iigp1 | interferon inducible GTPase 1 | 0.316 | ||
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.301 | ||
| Chuk | conserved helix-loop-helix ubiquitous kinase | 0.293 | Mouse | |
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.287 | ||
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.266 | ||
| Samd9l | sterile alpha motif domain containing 9-like | 0.246 | ||
| Irak1 | interleukin-1 receptor-associated kinase 1 | 0.240 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.236 | Mouse | |
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.231 | ||
| Usp18 | ubiquitin specific peptidase 18 | 0.224 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.223 | ||
| Gbp3 | guanylate binding protein 3 | 0.213 | Mouse | |
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.207 | ||
| Traf3 | TNF receptor-associated factor 3 | 0.206 | ||
| Ifi44 | interferon-induced protein 44 | 0.205 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.199 | Mouse | |
| Gbp6 | guanylate binding protein 6 | 0.184 | Mouse | |
| Ifnar2 | interferon (alpha and beta) receptor 2 | 0.177 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.176 | ||
| Pyhin1 | pyrin and HIN domain family, member 1 | 0.173 | ||
| Erap1 | endoplasmic reticulum aminopeptidase 1 | 0.148 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.128 | ||
| Ifi35 | interferon-induced protein 35 | 0.120 | ||
| Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.120 | ||
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.119 | ||
| Isg15 | ISG15 ubiquitin-like modifier | 0.111 | ||
| Trim25 | tripartite motif-containing 25 | 0.106 | ||
| Irak4 | interleukin-1 receptor-associated kinase 4 | 0.105 | ||
| Cblb | Casitas B-lineage lymphoma b | 0.104 | ||
| Hspa9 | heat shock protein 9 | 0.104 | ||
| Traf3ip2 | TRAF3 interacting protein 2 | 0.103 | ||
| BC006779 | cDNA sequence BC006779 | 0.099 | ||
| Tor3a | torsin family 3, member A | 0.097 | ||
| Nfkbie | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.097 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.091 | ||
| Dtx3l | deltex 3-like (Drosophila) | 0.090 | ||
| Stat2 | signal transducer and activator of transcription 2 | 0.089 | ||
| Trim12a | tripartite motif-containing 12A | 0.088 | Mouse | |
| Sfpi1 | SFFV proviral integration 1 | 0.088 | ||
| Gbp10 | guanylate-binding protein 10 | 0.087 | Mouse | |
| Traf2 | TNF receptor-associated factor 2 | 0.086 | Mouse | |
| Irf5 | interferon regulatory factor 5 | 0.084 | Mouse | |
| Sykb | spleen tyrosine kinase | 0.082 | ||
| Ifi47 | interferon gamma inducible protein 47 | 0.075 | ||
| Parp12 | poly (ADP-ribose) polymerase family, member 12 | 0.072 | Mouse | |
| Cd274 | CD274 antigen | 0.071 | ||
| Irf1 | interferon regulatory factor 1 | 0.069 | ||
| Igh | immunoglobulin heavy chain complex | 0.068 | ||
| Casp8 | caspase 8 | 0.068 | ||
| Mnda | myeloid cell nuclear differentiation antigen | 0.067 | ||
| Herc6 | hect domain and RLD 6 | 0.065 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.063 | ||
| Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.062 | ||
| Cmpk2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.061 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.060 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.058 | ||
| Zbp1 | Z-DNA binding protein 1 | 0.057 | ||
| Ifi203 | interferon activated gene 203 | 0.056 | ||
| Gbp4 | guanylate binding protein 4 | 0.056 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.055 | ||
| Trim30d | tripartite motif-containing 30D | 0.053 | Mouse | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.052 | ||
| Ikzf3 | IKAROS family zinc finger 3 | 0.051 | ||
| Tlr2 | toll-like receptor 2 | 0.050 | ||
| Parp10 | poly (ADP-ribose) polymerase family, member 10 | 0.048 | ||
| Cd19 | CD19 antigen | 0.048 | ||
| Tgtp2 | T-cell specific GTPase 2 | 0.048 | ||
| 1810019J16Rik | RIKEN cDNA 1810019J16 gene | 0.045 | ||
| Rnf31 | ring finger protein 31 | 0.044 | ||
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.043 | ||
| Il1rn | interleukin 1 receptor antagonist | 0.040 | ||
| Rel | reticuloendotheliosis oncogene | 0.040 | ||
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.040 | ||
| Nlrc5 | NLR family, CARD domain containing 5 | 0.040 | ||
| Irf7 | interferon regulatory factor 7 | 0.039 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.038 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.038 | ||
| Cd79b | CD79B antigen | 0.037 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.037 | ||
| Ikbke | inhibitor of kappaB kinase epsilon | 0.036 | Mouse | |
| Apobec3 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 | 0.036 | ||
| Tap1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.035 | ||
| Mcl1 | myeloid cell leukemia sequence 1 | 0.034 | ||
| Tnf | tumor necrosis factor | 0.034 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.033 | ||
| Serpinb9 | serine (or cysteine) peptidase inhibitor, clade B, member 9 | 0.033 | ||
| Trim34a | tripartite motif-containing 34A | 0.033 | Mouse | |
| Tapbpl | TAP binding protein-like | 0.032 | ||
| Oas3 | 2'-5' oligoadenylate synthetase 3 | 0.031 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.031 | ||
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.031 | ||
| Tifa | TRAF-interacting protein with forkhead-associated domain | 0.031 | ||
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.030 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.030 | ||
| Samhd1 | SAM domain and HD domain, 1 | 0.029 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.029 | ||
| Prkcd | protein kinase C, delta | 0.029 | ||
| Irak3 | interleukin-1 receptor-associated kinase 3 | 0.029 | ||
| Icam1 | intercellular adhesion molecule 1 | 0.029 | ||
| Oasl1 | 2'-5' oligoadenylate synthetase-like 1 | 0.029 | ||
| Psme2 | proteasome (prosome, macropain) 28 subunit, beta | 0.028 | ||
| H2-Q7 | histocompatibility 2, Q region locus 7 | 0.028 | ||
| Slc15a3 | solute carrier family 15, member 3 | 0.027 | ||
| Epsti1 | epithelial stromal interaction 1 (breast) | 0.027 | ||
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.027 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.027 | ||
| D14Ertd668e | DNA segment, Chr 14, ERATO Doi 668, expressed | 0.027 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.027 | ||
| Trafd1 | TRAF type zinc finger domain containing 1 | 0.026 | ||
| Tmem106a | transmembrane protein 106A | 0.026 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.026 | ||
| Oas1b | 2'-5' oligoadenylate synthetase 1B | 0.025 | ||
| Ddx58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.025 | ||
| Lrpprc | leucine-rich PPR-motif containing | 0.025 | ||
| Rnf135 | ring finger protein 135 | 0.025 | Human | |
| Csprs | component of Sp100-rs | 0.024 | ||
| BC013712 | cDNA sequence BC013712 | 0.024 | ||
| Plagl2 | pleiomorphic adenoma gene-like 2 | 0.023 | ||
| Irf8 | interferon regulatory factor 8 | 0.023 | Mouse | |
| Itch | itchy, E3 ubiquitin protein ligase | 0.022 | ||
| Trim14 | tripartite motif-containing 14 | 0.022 | ||
| Irf4 | interferon regulatory factor 4 | 0.022 | Mouse | |
| Tank | TRAF family member-associated Nf-kappa B activator | 0.022 | ||
| Sp100 | nuclear antigen Sp100 | 0.022 | ||
| Gsdmd | gasdermin D | 0.021 | ||
| Mlkl | mixed lineage kinase domain-like | 0.021 | ||
| Sh3bp2 | SH3-domain binding protein 2 | 0.021 | ||
| Vwa5a | von Willebrand factor A domain containing 5A | 0.021 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.021 | ||
| Rnf41 | ring finger protein 41 | 0.020 | ||
| Rbm43 | RNA binding motif protein 43 | 0.020 | ||
| Trim5 | tripartite motif-containing 5 | 0.020 | Mouse | |
| Adar | adenosine deaminase, RNA-specific | 0.020 | ||
| Clec4e | C-type lectin domain family 4, member e | 0.020 | ||
| Oas1a | 2'-5' oligoadenylate synthetase 1A | 0.020 | ||
| Becn1 | beclin 1, autophagy related | 0.019 | ||
| Zcchc6 | zinc finger, CCHC domain containing 6 | 0.019 | ||
| Pdcd1lg2 | programmed cell death 1 ligand 2 | 0.018 | ||
| Znfx1 | zinc finger, NFX1-type containing 1 | 0.018 | ||
| Bst2 | bone marrow stromal cell antigen 2 | 0.018 | ||
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.018 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.017 | ||
| Cd300ld | CD300 molecule-like family member d | 0.017 | ||
| Cd84 | CD84 antigen | 0.017 | ||
| Adap2 | ArfGAP with dual PH domains 2 | 0.017 | ||
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.017 | ||
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.017 | ||
| Oas2 | 2'-5' oligoadenylate synthetase 2 | 0.017 | ||
| Psme1 | proteasome (prosome, macropain) 28 subunit, alpha | 0.016 | ||
| Aicda | activation-induced cytidine deaminase | 0.016 | ||
| Zc3hav1 | zinc finger CCCH type, antiviral 1 | 0.016 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.016 | ||
| Tlr3 | toll-like receptor 3 | 0.016 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.016 | ||
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.016 | ||
| H2-M3 | histocompatibility 2, M region locus 3 | 0.016 | ||
| Prkd2 | protein kinase D2 | 0.016 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.016 | ||
| Dhx30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.016 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.016 | ||
| Slamf8 | SLAM family member 8 | 0.016 | ||
| 2010106G01Rik | RIKEN cDNA 2010106G01 gene | 0.016 | ||
| Slfn2 | schlafen 2 | 0.016 | ||
| Tnfrsf14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.016 | ||
| Hpgds | hematopoietic prostaglandin D synthase | 0.015 | ||
| Psmb10 | proteasome (prosome, macropain) subunit, beta type 10 | 0.015 | ||
| Vav1 | vav 1 oncogene | 0.015 | ||
| Gm12185 | predicted gene 12185 | 0.015 | ||
| Cd33 | CD33 antigen | 0.015 | ||
| Ube2l6 | ubiquitin-conjugating enzyme E2L 6 | 0.015 | ||
| Tapbp | TAP binding protein | 0.015 | ||
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.014 | ||
| Naip1 | NLR family, apoptosis inhibitory protein 1 | 0.014 | ||
| Ubp1 | upstream binding protein 1 | 0.014 | ||
| Parp4 | poly (ADP-ribose) polymerase family, member 4 | 0.014 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.014 | ||
| Pion | pigeon homolog (Drosophila) | 0.014 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.014 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.014 | ||
| Drosha | drosha, ribonuclease type III | 0.014 | ||
| Atg16l1 | autophagy-related 16-like 1 (yeast) | 0.013 | ||
| Trim12c | tripartite motif-containing 12C | 0.013 | Mouse | |
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.013 | ||
| Ly96 | lymphocyte antigen 96 | 0.013 | ||
| Tlr7 | toll-like receptor 7 | 0.013 | ||
| Clk1 | CDC-like kinase 1 | 0.013 | ||
| Nod1 | nucleotide-binding oligomerization domain containing 1 | 0.013 | ||
| Cd86 | CD86 antigen | 0.013 | ||
| Tmem173 | transmembrane protein 173 | 0.013 | ||
| Cd22 | CD22 antigen | 0.013 | ||
| Trim56 | tripartite motif-containing 56 | 0.013 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.013 | ||
| Slc37a2 | solute carrier family 37 (glycerol-3-phosphate transporter), member 2 | 0.013 | ||
| Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.013 | ||
| Gbp9 | guanylate-binding protein 9 | 0.013 | Mouse | |
| Tlr9 | toll-like receptor 9 | 0.013 | ||
| Aim1 | absent in melanoma 1 | 0.013 | ||
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.013 | ||
| N4bp1 | NEDD4 binding protein 1 | 0.013 | ||
| H2-T10 | histocompatibility 2, T region locus 10 | 0.012 | ||
| Cd180 | CD180 antigen | 0.012 | Mouse | |
| Gmip | Gem-interacting protein | 0.012 | ||
| Gvin1 | GTPase, very large interferon inducible 1 | 0.012 | ||
| Kif3b | kinesin family member 3B | 0.012 | ||
| Runx3 | runt related transcription factor 3 | 0.012 | ||
| Rab32 | RAB32, member RAS oncogene family | 0.012 | ||
| Apbb1ip | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein | 0.012 | ||
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.012 | ||
| Otud7b | OTU domain containing 7B | 0.012 | ||
| Ankfy1 | ankyrin repeat and FYVE domain containing 1 | 0.012 | ||
| Ctage5 | CTAGE family, member 5 | 0.012 | ||
| Tlr1 | toll-like receptor 1 | 0.012 | Mouse | |
| Atr | ataxia telangiectasia and Rad3 related | 0.012 | ||
| AB124611 | cDNA sequence AB124611 | 0.012 | ||
| Parp3 | poly (ADP-ribose) polymerase family, member 3 | 0.012 | ||
| Crtc2 | CREB regulated transcription coactivator 2 | 0.012 | ||
| Tlr11 | toll-like receptor 11 | 0.012 | Mouse | |
| Mov10 | Moloney leukemia virus 10 | 0.012 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.011 | ||
| Siae | sialic acid acetylesterase | 0.011 | ||
| E330016A19Rik | RIKEN cDNA E330016A19 gene | 0.011 | ||
| Sptlc2 | serine palmitoyltransferase, long chain base subunit 2 | 0.011 | ||
| Dhx58 | DEXH (Asp-Glu-X-His) box polypeptide 58 | 0.011 | ||
| Tdrd7 | tudor domain containing 7 | 0.011 | ||
| Polg | polymerase (DNA directed), gamma | 0.011 | ||
| Bmf | BCL2 modifying factor | 0.011 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.011 | ||
| Itga4 | integrin alpha 4 | 0.011 | ||
| Birc2 | baculoviral IAP repeat-containing 2 | 0.011 | ||
| Cd44 | CD44 antigen | 0.011 | ||
| Plekhn1 | pleckstrin homology domain containing, family N member 1 | 0.011 | ||
| Arid3a | AT rich interactive domain 3A (BRIGHT-like) | 0.011 | ||
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.011 | ||
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.011 | ||
| Taf1a | TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A | 0.011 | ||
| Gm885 | predicted gene 885 | 0.011 | ||
| Mcm3ap | minichromosome maintenance deficient 3 (S. cerevisiae) associated protein | 0.010 | ||
| Mx2 | myxovirus (influenza virus) resistance 2 | 0.010 | ||
| Abcg3 | ATP-binding cassette, sub-family G (WHITE), member 3 | 0.010 | ||
| Trim26 | tripartite motif-containing 26 | 0.010 | ||
| Anks3 | ankyrin repeat and sterile alpha motif domain containing 3 | 0.010 | ||
| Rasa4 | RAS p21 protein activator 4 | 0.010 | ||
| Il2ra | interleukin 2 receptor, alpha chain | 0.010 | ||
| Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.010 | ||
| Myo1g | myosin IG | 0.010 | ||
| Pml | promyelocytic leukemia | 0.010 | ||
| Tor1aip1 | torsin A interacting protein 1 | 0.010 | ||
| Pkhd1l1 | polycystic kidney and hepatic disease 1-like 1 | 0.010 |