IMP: Integrative Multi-species Prediction

Mus musculus

123 genes annotated in mouse

Multi-species View

negative regulation of cell cycle

GO:0045786

Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cell cycle"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Rb1	retinoblastoma 1	1.000
Mdm2	transformed mouse 3T3 cell double minute 2	0.999	Human Zebrafish
Smad4	MAD homolog 4 (Drosophila)	0.995
Brca1	breast cancer 1	0.994	Human
Apc	adenomatosis polyposis coli	0.992	Human
Pten	phosphatase and tensin homolog	0.991	Human
Shh	sonic hedgehog	0.991
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.988
Ctnnb1	catenin (cadherin associated protein), beta 1	0.984
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.981
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.977
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.973	Fly
Mdm4	transformed mouse 3T3 cell double minute 4	0.966
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.961	Human
E2f1	E2F transcription factor 1	0.941
Brca2	breast cancer 2	0.935
Rbl1	retinoblastoma-like 1 (p107)	0.883	Mouse Worm Fly
Gli3	GLI-Kruppel family member GLI3	0.878
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.874
Cdk4	cyclin-dependent kinase 4	0.862	Human
Ptch1	patched homolog 1	0.862
Nbn	nibrin	0.861
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.859
Neurod1	neurogenic differentiation 1	0.844
Fgfr2	fibroblast growth factor receptor 2	0.831
Cdk1	cyclin-dependent kinase 1	0.801
Rara	retinoic acid receptor, alpha	0.792
Msh2	mutS homolog 2 (E. coli)	0.786
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.755	Fly
Bmp4	bone morphogenetic protein 4	0.740	Human
Gata4	GATA binding protein 4	0.739	Mouse
Cdk2	cyclin-dependent kinase 2	0.737	Yeast Mouse
Fzd8	frizzled homolog 8 (Drosophila)	0.726	Mouse
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.703
Gli2	GLI-Kruppel family member GLI2	0.702
Smad3	MAD homolog 3 (Drosophila)	0.700	Human Worm
Braf	Braf transforming gene	0.672
Atm	ataxia telangiectasia mutated homolog (human)	0.634	Human Fly
Hes1	hairy and enhancer of split 1 (Drosophila)	0.626
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.620
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.615	Yeast
Hells	helicase, lymphoid specific	0.611
En1	engrailed 1	0.601
Fgfr1	fibroblast growth factor receptor 1	0.594	Mouse
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.594
Sox9	SRY-box containing gene 9	0.584
Nf1	neurofibromatosis 1	0.582
Mybl2	myeloblastosis oncogene-like 2	0.580
Rbl2	retinoblastoma-like 2	0.579	Mouse Worm Fly
Id1	inhibitor of DNA binding 1	0.566	Mouse
Smo	smoothened homolog (Drosophila)	0.562	Fly
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.551	Fly
Lin9	lin-9 homolog (C. elegans)	0.550
Lmnb1	lamin B1	0.543	Worm
Prc1	protein regulator of cytokinesis 1	0.542
Smc2	structural maintenance of chromosomes 2	0.536	Yeast
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.530
Bcl2	B-cell leukemia/lymphoma 2	0.525
Tcf3	transcription factor 3	0.524
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.515	Worm Fly
Smad1	MAD homolog 1 (Drosophila)	0.512	Worm Fly
Notch1	Notch gene homolog 1 (Drosophila)	0.496
Pthlh	parathyroid hormone-like peptide	0.490
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.487
Arid1b	AT rich interactive domain 1B (SWI-like)	0.485
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.470
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.465
Vhl	von Hippel-Lindau tumor suppressor	0.465
Aurkb	aurora kinase B	0.462
Jarid2	jumonji, AT rich interactive domain 2	0.460
Cenpk	centromere protein K	0.453
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.452
Amhr2	anti-Mullerian hormone type 2 receptor	0.450
Ccna2	cyclin A2	0.442
Cbx1	chromobox homolog 1 (Drosophila HP1 beta)	0.422
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.418	Human Zebrafish Rat
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.408
Add1	adducin 1 (alpha)	0.389
Dtl	denticleless homolog (Drosophila)	0.388	Zebrafish
Kit	kit oncogene	0.381
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.381
Blm	Bloom syndrome, RecQ helicase-like	0.379	Human
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.375	Yeast
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.370
Msx2	homeobox, msh-like 2	0.369
Casp1	caspase 1	0.363	Mouse
Plk4	polo-like kinase 4 (Drosophila)	0.362
Fst	follistatin	0.362
Kif23	kinesin family member 23	0.357
Cd80	CD80 antigen	0.354
Trp63	transformation related protein 63	0.352	Mouse
Ilk	integrin linked kinase	0.352	Rat
Cdk6	cyclin-dependent kinase 6	0.351	Human
Ccnd1	cyclin D1	0.350	Human
Meox2	mesenchyme homeobox 2	0.349
Foxa2	forkhead box A2	0.348
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.347
Hdac1	histone deacetylase 1	0.346
Id3	inhibitor of DNA binding 3	0.343	Mouse
Rxra	retinoid X receptor alpha	0.339
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.338
Mecom	MDS1 and EVI1 complex locus	0.336
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.335
Hif1a	hypoxia inducible factor 1, alpha subunit	0.333
Ttk	Ttk protein kinase	0.331	Yeast Zebrafish Fly
Xpa	xeroderma pigmentosum, complementation group A	0.330
Plk1	polo-like kinase 1 (Drosophila)	0.329	Human Mouse
Raf1	v-raf-leukemia viral oncogene 1	0.326
Tsc1	tuberous sclerosis 1	0.324
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.319
Snai1	snail homolog 1 (Drosophila)	0.319	Fly
Foxo3	forkhead box O3	0.318	Mouse
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.317	Fly
Gja1	gap junction protein, alpha 1	0.315
Stk11	serine/threonine kinase 11	0.314	Human
Thbs1	thrombospondin 1	0.313	Human
Pfn1	profilin 1	0.312
Pax3	paired box gene 3	0.310
Parp1	poly (ADP-ribose) polymerase family, member 1	0.310
Crebbp	CREB binding protein	0.308
Kitl	kit ligand	0.306
Axin1	axin 1	0.300
Pou5f1	POU domain, class 5, transcription factor 1	0.299
Rfc1	replication factor C (activator 1) 1	0.299
Skil	SKI-like	0.298
Neurog2	neurogenin 2	0.295	Mouse
Orc1	origin recognition complex, subunit 1	0.289
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.288	Fly
Sox11	SRY-box containing gene 11	0.287	Human
Smc3	structural maintenace of chromosomes 3	0.287	Human
H2afx	H2A histone family, member X	0.283
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.283
Cul4a	cullin 4A	0.283	Fly
Sufu	suppressor of fused homolog (Drosophila)	0.282
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.279
Ccnf	cyclin F	0.277	Human
Pax9	paired box gene 9	0.275
Rad51ap1	RAD51 associated protein 1	0.273
Lmna	lamin A	0.272	Worm
Ep300	E1A binding protein p300	0.271
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.271
Bax	BCL2-associated X protein	0.269	Mouse
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.266
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.263
Col2a1	collagen, type II, alpha 1	0.262
Mecp2	methyl CpG binding protein 2	0.260
Trim59	tripartite motif-containing 59	0.259
Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	0.259
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.258
Notch2	Notch gene homolog 2 (Drosophila)	0.258	Human
Egr2	early growth response 2	0.255
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.253
Kif2c	kinesin family member 2C	0.252
Otx2	orthodenticle homolog 2 (Drosophila)	0.252
Ncoa3	nuclear receptor coactivator 3	0.250
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.250
Hoxd13	homeobox D13	0.249
Aurka	aurora kinase A	0.247
Kif20a	kinesin family member 20A	0.247
Topbp1	topoisomerase (DNA) II binding protein 1	0.246	Fly
Brd4	bromodomain containing 4	0.243	Human
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.242
Creb1	cAMP responsive element binding protein 1	0.242
Sox4	SRY-box containing gene 4	0.241	Human
Gdnf	glial cell line derived neurotrophic factor	0.241
Stat3	signal transducer and activator of transcription 3	0.240
Gata5	GATA binding protein 5	0.239	Mouse
Myc	myelocytomatosis oncogene	0.239	Human
Esr1	estrogen receptor 1 (alpha)	0.235
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.233
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.232
Kif11	kinesin family member 11	0.231	Worm
A930001N09Rik	RIKEN cDNA A930001N09 gene	0.230
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.229
Foxp1	forkhead box P1	0.228
Dna2	DNA replication helicase 2 homolog (yeast)	0.228
Fgfr3	fibroblast growth factor receptor 3	0.227
Ahr	aryl-hydrocarbon receptor	0.226
Tcf19	transcription factor 19	0.223
Gtse1	G two S phase expressed protein 1	0.222
Fadd	Fas (TNFRSF6)-associated via death domain	0.221
Mis18bp1	MIS18 binding protein 1	0.220
Runx2	runt related transcription factor 2	0.220	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.219	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.218
Wnt5a	wingless-related MMTV integration site 5A	0.218	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.218
Lif	leukemia inhibitory factor	0.215
Cdca7	cell division cycle associated 7	0.211
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.210
Efnb1	ephrin B1	0.209
Ccne2	cyclin E2	0.209	Worm Fly
Wls	wntless homolog (Drosophila)	0.209
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.208
Prlr	prolactin receptor	0.206
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.204
Prrx2	paired related homeobox 2	0.203
Foxo1	forkhead box O1	0.201	Mouse
Spnb2	spectrin beta 2	0.198
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.197	Fly
Smc1a	structural maintenance of chromosomes 1A	0.196	Human
Tsc2	tuberous sclerosis 2	0.195
Foxc1	forkhead box C1	0.193	Human
Bmi1	Bmi1 polycomb ring finger oncogene	0.192
Ar	androgen receptor	0.191
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.190
Ccnb1	cyclin B1	0.189	Human
Pbx1	pre B-cell leukemia transcription factor 1	0.187
Krt14	keratin 14	0.186
Sae1	SUMO1 activating enzyme subunit 1	0.186
Ccnd2	cyclin D2	0.185
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.184
Prrx1	paired related homeobox 1	0.182
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.180
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.179
Hoxa5	homeobox A5	0.177
Neurod4	neurogenic differentiation 4	0.177	Mouse
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.177	Human
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.176
Pola1	polymerase (DNA directed), alpha 1	0.175
Mapk14	mitogen-activated protein kinase 14	0.170
Nhlh1	nescient helix loop helix 1	0.170	Mouse
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.169	Human
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.169
Tmpo	thymopoietin	0.169
Efnb2	ephrin B2	0.168
Gopc	golgi associated PDZ and coiled-coil motif containing	0.168
Gps1	G protein pathway suppressor 1	0.168	Fly
Atf2	activating transcription factor 2	0.167	Human
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.167
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.164
Birc5	baculoviral IAP repeat-containing 5	0.164
Pdx1	pancreatic and duodenal homeobox 1	0.164
Hmgb1	high mobility group box 1	0.163
Stil	Scl/Tal1 interrupting locus	0.162
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.162
Usp1	ubiquitin specific peptidase 1	0.161
Top2a	topoisomerase (DNA) II alpha	0.159	Yeast
Atf4	activating transcription factor 4	0.158
Lbr	lamin B receptor	0.157
Daxx	Fas death domain-associated protein	0.157
Wnt7a	wingless-related MMTV integration site 7A	0.156	Mouse
Ect2	ect2 oncogene	0.156
Cops6	COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)	0.156
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.155
Trip13	thyroid hormone receptor interactor 13	0.155
Hoxa1	homeobox A1	0.155
Cnot1	CCR4-NOT transcription complex, subunit 1	0.154
Nab2	Ngfi-A binding protein 2	0.154
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.152	Mouse
Dek	DEK oncogene (DNA binding)	0.151
Pea15a	phosphoprotein enriched in astrocytes 15A	0.151
Inpp5k	inositol polyphosphate 5-phosphatase K	0.149
Pkd1	polycystic kidney disease 1 homolog	0.147
Anln	anillin, actin binding protein	0.146
Kif4	kinesin family member 4	0.146
Lef1	lymphoid enhancer binding factor 1	0.145
Pax6	paired box gene 6	0.144
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.144
Kif22	kinesin family member 22	0.143
Dusp1	dual specificity phosphatase 1	0.143
Ckap2	cytoskeleton associated protein 2	0.142
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.142	Worm Fly
Nup107	nucleoporin 107	0.142
Rad21	RAD21 homolog (S. pombe)	0.142
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.142
Isl1	ISL1 transcription factor, LIM/homeodomain	0.142
Fen1	flap structure specific endonuclease 1	0.141
Bard1	BRCA1 associated RING domain 1	0.140
Foxc2	forkhead box C2	0.139
Stag1	stromal antigen 1	0.139
Lrp6	low density lipoprotein receptor-related protein 6	0.137
Wwox	WW domain-containing oxidoreductase	0.137
Bptf	bromodomain PHD finger transcription factor	0.136	Fly
Tgfb2	transforming growth factor, beta 2	0.136	Human Mouse
Il18	interleukin 18	0.135
Sfn	stratifin	0.135	Yeast
Wnt10b	wingless related MMTV integration site 10b	0.135
Socs1	suppressor of cytokine signaling 1	0.135
Ccne1	cyclin E1	0.135	Worm Fly
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.133
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.133
Ypel3	yippee-like 3 (Drosophila)	0.133
Actl6a	actin-like 6A	0.132
Cdt1	chromatin licensing and DNA replication factor 1	0.132
Arid1a	AT rich interactive domain 1A (SWI-like)	0.132
Zfhx3	zinc finger homeobox 3	0.131
Onecut1	one cut domain, family member 1	0.131
Nptx1	neuronal pentraxin 1	0.131
Haus6	HAUS augmin-like complex, subunit 6	0.131
E2f8	E2F transcription factor 8	0.130
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.130
Shox2	short stature homeobox 2	0.129
Msx1	homeobox, msh-like 1	0.129
Fgf8	fibroblast growth factor 8	0.129
Bak1	BCL2-antagonist/killer 1	0.129	Mouse
Yap1	yes-associated protein 1	0.129
Gsg2	germ cell-specific gene 2	0.129
Nf2	neurofibromatosis 2	0.128	Fly
Arpc4	actin related protein 2/3 complex, subunit 4	0.128
Nkx2-1	NK2 homeobox 1	0.126
Arhgap1	Rho GTPase activating protein 1	0.126
Fbxo32	F-box protein 32	0.125
Tnks1bp1	tankyrase 1 binding protein 1	0.125
Psme3	proteaseome (prosome, macropain) 28 subunit, 3	0.124
Dok1	docking protein 1	0.124
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.124	Fly
Smn1	survival motor neuron 1	0.124	Worm
Tfdp2	transcription factor Dp 2	0.123
Prim1	DNA primase, p49 subunit	0.121
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.121
Zc3h18	zinc finger CCCH-type containing 18	0.119
Rc3h1	RING CCCH (C3H) domains 1	0.119
Irf1	interferon regulatory factor 1	0.119	Human
Mapk3	mitogen-activated protein kinase 3	0.119	Yeast Worm
Rrm1	ribonucleotide reductase M1	0.119
Bcl2l1	BCL2-like 1	0.118	Human Mouse
Ntf3	neurotrophin 3	0.118
Cdca8	cell division cycle associated 8	0.117
Arx	aristaless related homeobox	0.116
Atr	ataxia telangiectasia and Rad3 related	0.115	Fly
Rfc4	replication factor C (activator 1) 4	0.115
Osbpl11	oxysterol binding protein-like 11	0.114
Chuk	conserved helix-loop-helix ubiquitous kinase	0.114
Cd151	CD151 antigen	0.114
Aim2	absent in melanoma 2	0.113
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.112
Hdac2	histone deacetylase 2	0.112
Pou4f2	POU domain, class 4, transcription factor 2	0.112
App	amyloid beta (A4) precursor protein	0.112
Smc4	structural maintenance of chromosomes 4	0.111
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.111
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.111
Hoxc5	homeobox C5	0.110
Gsk3b	glycogen synthase kinase 3 beta	0.110
Banf1	barrier to autointegration factor 1	0.110
Pitx2	paired-like homeodomain transcription factor 2	0.110
Bmp5	bone morphogenetic protein 5	0.110
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.108
Pgr	progesterone receptor	0.108
Dab1	disabled homolog 1 (Drosophila)	0.108
Fzd7	frizzled homolog 7 (Drosophila)	0.108	Mouse
Ncaph	non-SMC condensin I complex, subunit H	0.108
Cbl	Casitas B-lineage lymphoma	0.108
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.108
Brd2	bromodomain containing 2	0.107
Nos3	nitric oxide synthase 3, endothelial cell	0.107
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.107	Fly
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.106	Yeast
Twist1	twist homolog 1 (Drosophila)	0.106	Mouse
Igbp1	immunoglobulin (CD79A) binding protein 1	0.106
Spag5	sperm associated antigen 5	0.106
Skp2	S-phase kinase-associated protein 2 (p45)	0.106
Cdc7	cell division cycle 7 (S. cerevisiae)	0.105	Yeast
Irs1	insulin receptor substrate 1	0.105
Cdh1	cadherin 1	0.105
Casp3	caspase 3	0.105
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.105
Ret	ret proto-oncogene	0.105
Tlx3	T-cell leukemia, homeobox 3	0.105
Zeb1	zinc finger E-box binding homeobox 1	0.104
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.104
Bad	BCL2-associated agonist of cell death	0.104
Fbn1	fibrillin 1	0.104
Hist1h2bc	histone cluster 1, H2bc	0.104
Cdx2	caudal type homeobox 2	0.103
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.103	Fly
Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.103
Ccdc99	coiled-coil domain containing 99	0.102
Dmtf1	cyclin D binding myb-like transcription factor 1	0.102
Ooep	oocyte expressed protein homolog (dog)	0.102
Racgap1	Rac GTPase-activating protein 1	0.102
Axin2	axin2	0.102
Zcchc14	zinc finger, CCHC domain containing 14	0.101
Ruvbl2	RuvB-like protein 2	0.100
Eya4	eyes absent 4 homolog (Drosophila)	0.100
Cenpc1	centromere protein C1	0.099
Alx3	aristaless-like homeobox 3	0.098
Alx4	aristaless-like homeobox 4	0.098
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.098
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.098
Zfp503	zinc finger protein 503	0.098
Pax2	paired box gene 2	0.098
Lmx1a	LIM homeobox transcription factor 1 alpha	0.098
Gas1	growth arrest specific 1	0.097	Human
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.097
Epha1	Eph receptor A1	0.097
Zfp362	zinc finger protein 362	0.097
Gja8	gap junction protein, alpha 8	0.096
Jun	Jun oncogene	0.096
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.095
Trrap	transformation/transcription domain-associated protein	0.095
Ptk2	PTK2 protein tyrosine kinase 2	0.094
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.094
Stag2	stromal antigen 2	0.093	Human
Cdh6	cadherin 6	0.093
Smarcb1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.093
Mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.093
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.093
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.092
Fzd4	frizzled homolog 4 (Drosophila)	0.092	Mouse
Rint1	RAD50 interactor 1	0.092
Emx2	empty spiracles homolog 2 (Drosophila)	0.092
Hoxa2	homeobox A2	0.091
Gsx1	GS homeobox 1	0.091
Porcn	porcupine homolog (Drosophila)	0.090
Men1	multiple endocrine neoplasia 1	0.090
Bmp8b	bone morphogenetic protein 8b	0.090
Zfp36	zinc finger protein 36	0.089
Kat2a	K(lysine) acetyltransferase 2A	0.089	Mouse
Phox2b	paired-like homeobox 2b	0.089
Cdca5	cell division cycle associated 5	0.088
Mms22l	MMS22-like, DNA repair protein	0.088
Nrg1	neuregulin 1	0.088
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.087
Nlrp3	NLR family, pyrin domain containing 3	0.087
Sp1	trans-acting transcription factor 1	0.087
Trp73	transformation related protein 73	0.087
Hoxb5	homeobox B5	0.087
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.087
Hbegf	heparin-binding EGF-like growth factor	0.086
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.086
Igh	immunoglobulin heavy chain complex	0.086
Wnt6	wingless-related MMTV integration site 6	0.086	Mouse
Purb	purine rich element binding protein B	0.086
T	brachyury	0.086
Plagl2	pleiomorphic adenoma gene-like 2	0.086
Ubr7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0.086
Prox1	prospero-related homeobox 1	0.086
Chd7	chromodomain helicase DNA binding protein 7	0.086
Huwe1	HECT, UBA and WWE domain containing 1	0.086
Rcc2	regulator of chromosome condensation 2	0.085
Ccnb2	cyclin B2	0.085
Ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.085
Bach1	BTB and CNC homology 1	0.085
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.085
Rac1	RAS-related C3 botulinum substrate 1	0.085
Klf3	Kruppel-like factor 3 (basic)	0.085
Stk4	serine/threonine kinase 4	0.084
Pum1	pumilio 1 (Drosophila)	0.084
Nlrp5	NLR family, pyrin domain containing 5	0.084
Tbx15	T-box 15	0.084
Mapk1	mitogen-activated protein kinase 1	0.084	Yeast Worm
Tdp2	tyrosyl-DNA phosphodiesterase 2	0.084
Kl	klotho	0.084
Runx3	runt related transcription factor 3	0.084
Notch3	Notch gene homolog 3 (Drosophila)	0.084
Ihh	Indian hedgehog	0.083
Cnot7	CCR4-NOT transcription complex, subunit 7	0.083	Worm
Usp22	ubiquitin specific peptidase 22	0.083
Sox1	SRY-box containing gene 1	0.083
Foxn1	forkhead box N1	0.083
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.083	Worm Fly
Pofut1	protein O-fucosyltransferase 1	0.083
Dbnl	drebrin-like	0.082
Atad5	ATPase family, AAA domain containing 5	0.082
Clip1	CAP-GLY domain containing linker protein 1	0.082
Cops3	COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)	0.082	Fly
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.082
Mstn	myostatin	0.082	Mouse
Aimp2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	0.081
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.081	Yeast
Capzb	capping protein (actin filament) muscle Z-line, beta	0.081
Abtb1	ankyrin repeat and BTB (POZ) domain containing 1	0.081
Vdr	vitamin D receptor	0.080
Bik	BCL2-interacting killer	0.080
Tacc3	transforming, acidic coiled-coil containing protein 3	0.080
Rarb	retinoic acid receptor, beta	0.080
Ptf1a	pancreas specific transcription factor, 1a	0.080	Mouse
Hoxb9	homeobox B9	0.080
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.080
Ncapd2	non-SMC condensin I complex, subunit D2	0.080
Txnip	thioredoxin interacting protein	0.079
Akap3	A kinase (PRKA) anchor protein 3	0.079
Plec	plectin	0.079
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.079
Evx1	even skipped homeotic gene 1 homolog	0.079
Cenpa	centromere protein A	0.078
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.078
Anapc2	anaphase promoting complex subunit 2	0.078
Itgb5	integrin beta 5	0.078
Adsl	adenylosuccinate lyase	0.078
Esr2	estrogen receptor 2 (beta)	0.078
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.078	Worm Fly
Smc6	structural maintenance of chromosomes 6	0.078
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.077
Hnrpll	heterogeneous nuclear ribonucleoprotein L-like	0.077
Fgf18	fibroblast growth factor 18	0.077
Adam17	a disintegrin and metallopeptidase domain 17	0.077
Il3	interleukin 3	0.077
Vasp	vasodilator-stimulated phosphoprotein	0.077
Gpr50	G-protein-coupled receptor 50	0.077
Hmga2	high mobility group AT-hook 2	0.077
Dlx6	distal-less homeobox 6	0.076
Rnft1	ring finger protein, transmembrane 1	0.076
Rfwd2	ring finger and WD repeat domain 2	0.076
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.076
Sim2	single-minded homolog 2 (Drosophila)	0.076
Ephb2	Eph receptor B2	0.075
Pax7	paired box gene 7	0.075
Sap18	Sin3-associated polypeptide 18	0.075
Mlh1	mutL homolog 1 (E. coli)	0.075
Acd	adrenocortical dysplasia	0.075
Pcna	proliferating cell nuclear antigen	0.075
Cops2	COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)	0.075
Hoxd8	homeobox D8	0.074
Chd2	chromodomain helicase DNA binding protein 2	0.074
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.074
Chek2	CHK2 checkpoint homolog (S. pombe)	0.074	Human Fly
Myb	myeloblastosis oncogene	0.074
Lama5	laminin, alpha 5	0.074
Stra6	stimulated by retinoic acid gene 6	0.074
Des	desmin	0.074
Epha2	Eph receptor A2	0.074
Sgol1	shugoshin-like 1 (S. pombe)	0.074
Rsf1	remodeling and spacing factor 1	0.074
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.073	Human
Mettl1	methyltransferase like 1	0.073
Wnt4	wingless-related MMTV integration site 4	0.072	Mouse
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.072
Tcf4	transcription factor 4	0.072
Ccni	cyclin I	0.072
Adcy9	adenylate cyclase 9	0.072
Klhl24	kelch-like 24 (Drosophila)	0.072
Fos	FBJ osteosarcoma oncogene	0.072
Plcd1	phospholipase C, delta 1	0.072
Emid2	EMI domain containing 2	0.072
Crb2	crumbs homolog 2 (Drosophila)	0.072
Psen1	presenilin 1	0.072
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.072
Taok1	TAO kinase 1	0.071
Gjb5	gap junction protein, beta 5	0.071
Tert	telomerase reverse transcriptase	0.071
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.071
Cyld	cylindromatosis (turban tumor syndrome)	0.071
Hes5	hairy and enhancer of split 5 (Drosophila)	0.071
Csf1	colony stimulating factor 1 (macrophage)	0.070
Smad7	MAD homolog 7 (Drosophila)	0.070
Cops7b	COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana)	0.070
Il23a	interleukin 23, alpha subunit p19	0.070
Zfp101	zinc finger protein 101	0.070
Wrn	Werner syndrome homolog (human)	0.070
Fzd1	frizzled homolog 1 (Drosophila)	0.069	Mouse
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.069
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.068
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.068
C78339	expressed sequence C78339	0.068
Olig2	oligodendrocyte transcription factor 2	0.068
Fbxl20	F-box and leucine-rich repeat protein 20	0.068
Adra2b	adrenergic receptor, alpha 2b	0.068
Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.068
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.068
Fbxo5	F-box protein 5	0.068
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.068
Hoxa10	homeobox A10	0.067
Sass6	spindle assembly 6 homolog (C. elegans)	0.067
Pou3f3	POU domain, class 3, transcription factor 3	0.067
Fzd2	frizzled homolog 2 (Drosophila)	0.067	Mouse
Tprgl	transformation related protein 63 regulated like	0.067
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.066
Lyzl4	lysozyme-like 4	0.066
Selp	selectin, platelet	0.066
Inhba	inhibin beta-A	0.066	Human
Prkci	protein kinase C, iota	0.066
Erg	avian erythroblastosis virus E-26 (v-ets) oncogene related	0.066
Mfsd4	major facilitator superfamily domain containing 4	0.066
Pkdcc	protein kinase domain containing, cytoplasmic	0.066
Mapt	microtubule-associated protein tau	0.066
Ube3a	ubiquitin protein ligase E3A	0.066
Dll1	delta-like 1 (Drosophila)	0.065
Kif18a	kinesin family member 18A	0.065
Efna4	ephrin A4	0.065
Ikzf1	IKAROS family zinc finger 1	0.065
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.065
Tgfb1	transforming growth factor, beta 1	0.065
Irf6	interferon regulatory factor 6	0.065	Human
Itga3	integrin alpha 3	0.065
Atp2c2	ATPase, Ca++ transporting, type 2C, member 2	0.065
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.065
Asxl1	additional sex combs like 1 (Drosophila)	0.065
Klf4	Kruppel-like factor 4 (gut)	0.065
Chd4	chromodomain helicase DNA binding protein 4	0.064	Fly
Uchl5	ubiquitin carboxyl-terminal esterase L5	0.064
Rel	reticuloendotheliosis oncogene	0.064
Neurog1	neurogenin 1	0.064	Mouse
Ptgdr	prostaglandin D receptor	0.064
Nrbp1	nuclear receptor binding protein 1	0.064
Acvr1b	activin A receptor, type 1B	0.064
Recql	RecQ protein-like	0.064
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.064
Pkn2	protein kinase N2	0.064
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.064
Pou3f2	POU domain, class 3, transcription factor 2	0.063
Ccng2	cyclin G2	0.063
Wnt1	wingless-related MMTV integration site 1	0.063	Mouse Fly
Mxd3	Max dimerization protein 3	0.063
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.063
Sox14	SRY-box containing gene 14	0.063
Smad2	MAD homolog 2 (Drosophila)	0.063	Worm
Foxd1	forkhead box D1	0.063
Ift140	intraflagellar transport 140 homolog (Chlamydomonas)	0.063
Rpa3	replication protein A3	0.063
Lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.063
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.063
Wdr19	WD repeat domain 19	0.063
Bglap	bone gamma carboxyglutamate protein	0.062
Sox3	SRY-box containing gene 3	0.062
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.062
Hnf4a	hepatic nuclear factor 4, alpha	0.062	Rat
Gbp2	guanylate binding protein 2	0.062
Foxm1	forkhead box M1	0.062	Human
Dab2ip	disabled homolog 2 (Drosophila) interacting protein	0.062	Human
Dlx5	distal-less homeobox 5	0.061
Obfc2b	oligonucleotide/oligosaccharide-binding fold containing 2B	0.061
Bhlha9	basic helix-loop-helix family, member a9	0.061
Rps6kb1	ribosomal protein S6 kinase, polypeptide 1	0.061	Mouse
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.061
Chrdl2	chordin-like 2	0.061
Wdr45	WD repeat domain 45	0.061
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.061	Fly
Spnb3	spectrin beta 3	0.061
Rnf19a	ring finger protein 19A	0.061
Foxf2	forkhead box F2	0.061
Ccndbp1	cyclin D-type binding-protein 1	0.061
Mtl5	metallothionein-like 5, testis-specific (tesmin)	0.061
Hdac3	histone deacetylase 3	0.061
Mki67	antigen identified by monoclonal antibody Ki 67	0.060
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.060
Irx2	Iroquois related homeobox 2 (Drosophila)	0.060
Foxp3	forkhead box P3	0.060
Nfic	nuclear factor I/C	0.060
Srsf2	serine/arginine-rich splicing factor 2	0.060
Mrto4	MRT4, mRNA turnover 4, homolog (S. cerevisiae)	0.060
Efna5	ephrin A5	0.060
Bnc1	basonuclin 1	0.060
Incenp	inner centromere protein	0.060
Capn1	calpain 1	0.060
Abi1	abl-interactor 1	0.060
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.060
Lrp5	low density lipoprotein receptor-related protein 5	0.060
Emx1	empty spiracles homolog 1 (Drosophila)	0.060
Src	Rous sarcoma oncogene	0.059
Psap	prosaposin	0.059
Edn3	endothelin 3	0.059
Mastl	microtubule associated serine/threonine kinase-like	0.059
Cdx1	caudal type homeobox 1	0.059
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.059	Yeast Fly
Hus1	Hus1 homolog (S. pombe)	0.059
Sct	secretin	0.059
Nup88	nucleoporin 88	0.059
Iqgap3	IQ motif containing GTPase activating protein 3	0.059
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.059
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.058
Hmgb2	high mobility group box 2	0.058
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.058
Wee1	WEE 1 homolog 1 (S. pombe)	0.058	Mouse Fly
Sesn1	sestrin 1	0.058
Myf5	myogenic factor 5	0.058	Mouse
Polr1a	polymerase (RNA) I polypeptide A	0.058
Zmym2	zinc finger, MYM-type 2	0.058
Adra2a	adrenergic receptor, alpha 2a	0.057
Rtkn	rhotekin	0.057
Gbp3	guanylate binding protein 3	0.057
Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha	0.057
Hexim1	hexamethylene bis-acetamide inducible 1	0.057	Human
Sox2	SRY-box containing gene 2	0.057	Human
Nkx6-1	NK6 homeobox 1	0.057
Gfi1	growth factor independent 1	0.057
Casp8ap2	caspase 8 associated protein 2	0.057
Ireb2	iron responsive element binding protein 2	0.057
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.057
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.057	Fly
Rpa1	replication protein A1	0.057
B230308N11Rik	RIKEN cDNA B230308N11 gene	0.056
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.056
Saal1	serum amyloid A-like 1	0.056
Sssca1	Sjogren's syndrome/scleroderma autoantigen 1 homolog (human)	0.056
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.056
Dusp6	dual specificity phosphatase 6	0.056
Cenpn	centromere protein N	0.056
Stat6	signal transducer and activator of transcription 6	0.056
Cxadr	coxsackie virus and adenovirus receptor	0.056
Glg1	golgi apparatus protein 1	0.056
Wnt11	wingless-related MMTV integration site 11	0.056	Mouse
Inha	inhibin alpha	0.056
Bdnf	brain derived neurotrophic factor	0.056
Timeless	timeless homolog (Drosophila)	0.056
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.056
Bmp7	bone morphogenetic protein 7	0.056	Human
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.056
Eftud2	elongation factor Tu GTP binding domain containing 2	0.056
Nodal	nodal	0.056
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.056
Foxd3	forkhead box D3	0.056
Tbx21	T-box 21	0.055
Fbxo15	F-box protein 15	0.055
Cops8	COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana)	0.055
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.055
Diap3	diaphanous homolog 3 (Drosophila)	0.055
Cops4	COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)	0.055
Mta2	metastasis-associated gene family, member 2	0.055
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.055
Mos	Moloney sarcoma oncogene	0.055
2610027L16Rik	RIKEN cDNA 2610027L16 gene	0.055
Ptch2	patched homolog 2	0.055
Nog	noggin	0.054
Rcc1	regulator of chromosome condensation 1	0.054
Nlk	nemo like kinase	0.054
Terf1	telomeric repeat binding factor 1	0.054	Human
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.054
2900010M23Rik	RIKEN cDNA 2900010M23 gene	0.054
Etaa1	Ewing's tumor-associated antigen 1	0.054
Dpysl2	dihydropyrimidinase-like 2	0.054
Mib1	mindbomb homolog 1 (Drosophila)	0.054
Kiss1	KiSS-1 metastasis-suppressor	0.054
Nusap1	nucleolar and spindle associated protein 1	0.054
Cxcr4	chemokine (C-X-C motif) receptor 4	0.054
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)	0.054
Slc12a8	solute carrier family 12 (potassium/chloride transporters), member 8	0.053
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.053
Hoxb4	homeobox B4	0.053
Cnih2	cornichon homolog 2 (Drosophila)	0.053
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.053
Crb1	crumbs homolog 1 (Drosophila)	0.053
Glis3	GLIS family zinc finger 3	0.053
Foxa1	forkhead box A1	0.053
Hoxb6	homeobox B6	0.053
Hdac5	histone deacetylase 5	0.052
Pdha2	pyruvate dehydrogenase E1 alpha 2	0.052
Sun1	Sad1 and UNC84 domain containing 1	0.052
Hp1bp3	heterochromatin protein 1, binding protein 3	0.052
H2afy	H2A histone family, member Y	0.052	Human
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.052
Mnda	myeloid cell nuclear differentiation antigen	0.052
Dlx3	distal-less homeobox 3	0.052
Amotl2	angiomotin-like 2	0.052
Ints7	integrator complex subunit 7	0.052
Wt1	Wilms tumor 1 homolog	0.052
Dlx2	distal-less homeobox 2	0.051
Phf1	PHD finger protein 1	0.051
Il1b	interleukin 1 beta	0.051
Inhbb	inhibin beta-B	0.051
Rim4	recombination induced mutation 4	0.051
Tbx3	T-box 3	0.051
Max	Max protein	0.051
Nae1	NEDD8 activating enzyme E1 subunit 1	0.051
Cnot6	CCR4-NOT transcription complex, subunit 6	0.051
Gnb1	guanine nucleotide binding protein (G protein), beta 1	0.051
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.050