IMP: Integrative Multi-species Prediction

Mus musculus

15 genes annotated in mouse

Multi-species View

regulation of lipase activity

GO:0060191

Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of lipase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of lipase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Ptk2	PTK2 protein tyrosine kinase 2	0.949
Cbl	Casitas B-lineage lymphoma	0.906
Apoe	apolipoprotein E	0.879
Prrx1	paired related homeobox 1	0.611
Ldlr	low density lipoprotein receptor	0.574
Sox9	SRY-box containing gene 9	0.572
Fyn	Fyn proto-oncogene	0.499	Mouse
Pnpla2	patatin-like phospholipase domain containing 2	0.478
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.451
Nos3	nitric oxide synthase 3, endothelial cell	0.435
Agtr1a	angiotensin II receptor, type 1a	0.423	Human
Runx2	runt related transcription factor 2	0.398
Lepr	leptin receptor	0.299
Pten	phosphatase and tensin homolog	0.291
Abhd5	abhydrolase domain containing 5	0.284
Bmp4	bone morphogenetic protein 4	0.248
Lrp1	low density lipoprotein receptor-related protein 1	0.202
Npc1	Niemann Pick type C1	0.199
Fgfr2	fibroblast growth factor receptor 2	0.193	Human
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.192
Was	Wiskott-Aldrich syndrome homolog (human)	0.189
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.182	Fly
Psen1	presenilin 1	0.179
Lrp6	low density lipoprotein receptor-related protein 6	0.175	Mouse
Fgfrl1	fibroblast growth factor receptor-like 1	0.169
Tbx3	T-box 3	0.165
Ren1	renin 1 structural	0.163
Lcat	lecithin cholesterol acyltransferase	0.161
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.155
Pdgfb	platelet derived growth factor, B polypeptide	0.148
Gli2	GLI-Kruppel family member GLI2	0.136
Dok2	docking protein 2	0.133
Apoa1	apolipoprotein A-I	0.125
Itgb2	integrin beta 2	0.118
Gsk3b	glycogen synthase kinase 3 beta	0.117
Ednrb	endothelin receptor type B	0.110
Bmp2	bone morphogenetic protein 2	0.109
Ghr	growth hormone receptor	0.108
Fgfr3	fibroblast growth factor receptor 3	0.107	Human
Fgf7	fibroblast growth factor 7	0.105
Rab6	RAB6, member RAS oncogene family	0.104
Folr2	folate receptor 2 (fetal)	0.101
Flt1	FMS-like tyrosine kinase 1	0.100	Human
Foxc2	forkhead box C2	0.099
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.097	Rat
Egfr	epidermal growth factor receptor	0.095
Gli3	GLI-Kruppel family member GLI3	0.094
Vdr	vitamin D receptor	0.090
Bmp5	bone morphogenetic protein 5	0.090
Trp53	transformation related protein 53	0.089
Prrx2	paired related homeobox 2	0.089
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.084
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.082	Human
Lpin1	lipin 1	0.078
Pthlh	parathyroid hormone-like peptide	0.078
Angptl4	angiopoietin-like 4	0.076
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.075	Human
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.070
Inpp5d	inositol polyphosphate-5-phosphatase D	0.068
Msx2	homeobox, msh-like 2	0.067
Ret	ret proto-oncogene	0.067
Ctgf	connective tissue growth factor	0.067	Mouse
Nrp1	neuropilin 1	0.065
Selp	selectin, platelet	0.065
Foxc1	forkhead box C1	0.064
Zeb1	zinc finger E-box binding homeobox 1	0.063
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.062
Pick1	protein interacting with C kinase 1	0.062
Vegfa	vascular endothelial growth factor A	0.061
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.061
Snai1	snail homolog 1 (Drosophila)	0.061
Lat	linker for activation of T cells	0.058
Apaf1	apoptotic peptidase activating factor 1	0.056
Fbln1	fibulin 1	0.056
Ngf	nerve growth factor	0.056
Sftpb	surfactant associated protein B	0.055
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.054
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.052
Duox2	dual oxidase 2	0.052
Cidec	cell death-inducing DFFA-like effector c	0.051
Angptl3	angiopoietin-like 3	0.050
Lox	lysyl oxidase	0.050
Becn1	beclin 1, autophagy related	0.049
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.049
Prlr	prolactin receptor	0.049
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.049
Prkce	protein kinase C, epsilon	0.048
Ctnnb1	catenin (cadherin associated protein), beta 1	0.048
F7	coagulation factor VII	0.046
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.046
Sox11	SRY-box containing gene 11	0.045
Ncr1	natural cytotoxicity triggering receptor 1	0.045
Mapk8	mitogen-activated protein kinase 8	0.044
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.043
Tcra	T-cell receptor alpha chain	0.043
Col12a1	collagen, type XII, alpha 1	0.041
Blnk	B-cell linker	0.041
Gpr97	G protein-coupled receptor 97	0.040
Fos	FBJ osteosarcoma oncogene	0.040
Dok1	docking protein 1	0.040
Ptgs2	prostaglandin-endoperoxide synthase 2	0.039
Cyr61	cysteine rich protein 61	0.038
Thra	thyroid hormone receptor alpha	0.038
Cnr2	cannabinoid receptor 2 (macrophage)	0.038
Wwc2	WW, C2 and coiled-coil domain containing 2	0.038
Agtr2	angiotensin II receptor, type 2	0.037
Ltbp2	latent transforming growth factor beta binding protein 2	0.037
Sox17	SRY-box containing gene 17	0.036
Plcg2	phospholipase C, gamma 2	0.035
Rxra	retinoid X receptor alpha	0.035
Notch2	Notch gene homolog 2 (Drosophila)	0.035
Fgfr1	fibroblast growth factor receptor 1	0.035	Human
Lrp5	low density lipoprotein receptor-related protein 5	0.035	Mouse
Fga	fibrinogen alpha chain	0.034
Ptprc	protein tyrosine phosphatase, receptor type, C	0.034
Ctsw	cathepsin W	0.034
Gpr182	G protein-coupled receptor 182	0.032
Amotl2	angiomotin-like 2	0.032
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.032
Gpc3	glypican 3	0.032
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.031
Tgfbr2	transforming growth factor, beta receptor II	0.031
Kng1	kininogen 1	0.031
Idua	iduronidase, alpha-L-	0.030
Twist2	twist homolog 2 (Drosophila)	0.030
Mmp11	matrix metallopeptidase 11	0.030
Itgb3	integrin beta 3	0.030
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.030
Sele	selectin, endothelial cell	0.030	Human
Zap70	zeta-chain (TCR) associated protein kinase	0.030
Fgfr4	fibroblast growth factor receptor 4	0.029
Ptpre	protein tyrosine phosphatase, receptor type, E	0.029
Pgr	progesterone receptor	0.029
Jun	Jun oncogene	0.029
Mn1	meningioma 1	0.028
Tbx5	T-box 5	0.028
Sorbs3	sorbin and SH3 domain containing 3	0.028
Smagp	small cell adhesion glycoprotein	0.028
Egr1	early growth response 1	0.027
Ang2	angiogenin, ribonuclease A family, member 2	0.027	Human
Reg2	regenerating islet-derived 2	0.026
Gnrh1	gonadotropin releasing hormone 1	0.026
Tfpi2	tissue factor pathway inhibitor 2	0.025
Amhr2	anti-Mullerian hormone type 2 receptor	0.025
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.025
Acvr1	activin A receptor, type 1	0.025
Tenc1	tensin like C1 domain-containing phosphatase	0.024
Cdh11	cadherin 11	0.024
Ctsk	cathepsin K	0.024
Csf1	colony stimulating factor 1 (macrophage)	0.023
Bdkrb2	bradykinin receptor, beta 2	0.023
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.023
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.023
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.023
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.023	Human
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.023
Hpx	hemopexin	0.023
Itgax	integrin alpha X	0.023
Dusp1	dual specificity phosphatase 1	0.022
Plg	plasminogen	0.022
Wisp2	WNT1 inducible signaling pathway protein 2	0.022	Mouse
Msln	mesothelin	0.022
Ltbp1	latent transforming growth factor beta binding protein 1	0.022
Grb2	growth factor receptor bound protein 2	0.022
Rgs4	regulator of G-protein signaling 4	0.021	Mouse
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.021
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.021
Ahsg	alpha-2-HS-glycoprotein	0.021
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.021
Clnk	cytokine-dependent hematopoietic cell linker	0.021
Mid2	midline 2	0.020
Tll1	tolloid-like	0.020
Igf1	insulin-like growth factor 1	0.019
Lmf1	lipase maturation factor 1	0.019
Cd40	CD40 antigen	0.019
Cd6	CD6 antigen	0.019
Fzd4	frizzled homolog 4 (Drosophila)	0.019
Ptch1	patched homolog 1	0.019
Thrb	thyroid hormone receptor beta	0.019
S1pr3	sphingosine-1-phosphate receptor 3	0.019
Pofut1	protein O-fucosyltransferase 1	0.019
Aqp2	aquaporin 2	0.019
Hcls1	hematopoietic cell specific Lyn substrate 1	0.019
Plcd1	phospholipase C, delta 1	0.019	Rat
Agtrap	angiotensin II, type I receptor-associated protein	0.019
Cd247	CD247 antigen	0.018
Lama5	laminin, alpha 5	0.018
F3	coagulation factor III	0.018
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.018
Rarb	retinoic acid receptor, beta	0.018
Cd86	CD86 antigen	0.018
Sulf2	sulfatase 2	0.018
Ednra	endothelin receptor type A	0.018
Umod	uromodulin	0.018
Cd28	CD28 antigen	0.018
Nradd	neurotrophin receptor associated death domain	0.017
Pzp	pregnancy zone protein	0.017
Meox2	mesenchyme homeobox 2	0.017
Mcoln2	mucolipin 2	0.017
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.017
Fosb	FBJ osteosarcoma oncogene B	0.017
Itga8	integrin alpha 8	0.017
Skap2	src family associated phosphoprotein 2	0.017
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.017
Mertk	c-mer proto-oncogene tyrosine kinase	0.017
Mrc2	mannose receptor, C type 2	0.017	Mouse
Prdm1	PR domain containing 1, with ZNF domain	0.017
Wasf2	WAS protein family, member 2	0.017
Mocs1	molybdenum cofactor synthesis 1	0.016
Fzd1	frizzled homolog 1 (Drosophila)	0.016
Nkx3-2	NK3 homeobox 2	0.016
Thbs2	thrombospondin 2	0.016
Inhba	inhibin beta-A	0.016
Rara	retinoic acid receptor, alpha	0.016
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.016
Lyl1	lymphoblastomic leukemia 1	0.016
Sell	selectin, lymphocyte	0.016
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.016
Slc12a1	solute carrier family 12, member 1	0.016
Cd3d	CD3 antigen, delta polypeptide	0.016
Thbs1	thrombospondin 1	0.016
Gna11	guanine nucleotide binding protein, alpha 11	0.016	Fly
Ccbp2	chemokine binding protein 2	0.016
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.016
Ptgir	prostaglandin I receptor (IP)	0.016
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.016	Human
Pla2r1	phospholipase A2 receptor 1	0.016
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.015
Smo	smoothened homolog (Drosophila)	0.015
Ncoa1	nuclear receptor coactivator 1	0.015
Plcb1	phospholipase C, beta 1	0.015
Plxna2	plexin A2	0.015
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.015
Vangl2	vang-like 2 (van gogh, Drosophila)	0.015
Lama4	laminin, alpha 4	0.015
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.015
Apc	adenomatosis polyposis coli	0.015
Cpe	carboxypeptidase E	0.015
Has2	hyaluronan synthase 2	0.014
Grm2	glutamate receptor, metabotropic 2	0.014
Sntg2	syntrophin, gamma 2	0.014
Ikzf1	IKAROS family zinc finger 1	0.014
Vim	vimentin	0.014
Gzmb	granzyme B	0.014
Il18rap	interleukin 18 receptor accessory protein	0.014
Wt1	Wilms tumor 1 homolog	0.014
Lpl	lipoprotein lipase	0.014
Apoc1	apolipoprotein C-I	0.014
Cd7	CD7 antigen	0.014
Fcgr1	Fc receptor, IgG, high affinity I	0.014
Nkg7	natural killer cell group 7 sequence	0.014
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.014
Irs2	insulin receptor substrate 2	0.014
Arhgap9	Rho GTPase activating protein 9	0.013
Sh2d1b1	SH2 domain protein 1B1	0.013
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.013
Mtap1b	microtubule-associated protein 1B	0.013
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.013
Epas1	endothelial PAS domain protein 1	0.013
Ccrl1	chemokine (C-C motif) receptor-like 1	0.013
Scg2	secretogranin II	0.013
Cd96	CD96 antigen	0.013
Rel	reticuloendotheliosis oncogene	0.013
Axl	AXL receptor tyrosine kinase	0.013
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.013
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.013
Hlx	H2.0-like homeobox	0.013
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.013
Fst	follistatin	0.013
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.013
Clec4f	C-type lectin domain family 4, member f	0.013
Dab2	disabled homolog 2 (Drosophila)	0.013
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.013	Human
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.013
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.013
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.013
Btk	Bruton agammaglobulinemia tyrosine kinase	0.013	Mouse
Ddr2	discoidin domain receptor family, member 2	0.012
Cd22	CD22 antigen	0.012
Cd5l	CD5 antigen-like	0.012
Wwtr1	WW domain containing transcription regulator 1	0.012
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.012
Npy1r	neuropeptide Y receptor Y1	0.012
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.012
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.012
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.012
Hdac5	histone deacetylase 5	0.012
Cbr2	carbonyl reductase 2	0.012
Snai2	snail homolog 2 (Drosophila)	0.012
Fam105a	family with sequence similarity 105, member A	0.012
Rhoj	ras homolog gene family, member J	0.012
Rasa3	RAS p21 protein activator 3	0.012
Gja1	gap junction protein, alpha 1	0.012
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.012
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.012
Tmed8	transmembrane emp24 domain containing 8	0.012
Gpx3	glutathione peroxidase 3	0.012
Cnn1	calponin 1	0.012
Bmx	BMX non-receptor tyrosine kinase	0.012	Mouse
Dnm1	dynamin 1	0.012
Pou2af1	POU domain, class 2, associating factor 1	0.012
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.012
Phldb1	pleckstrin homology-like domain, family B, member 1	0.012
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.012
Igf1r	insulin-like growth factor I receptor	0.011
Vipr2	vasoactive intestinal peptide receptor 2	0.011
Cxcr3	chemokine (C-X-C motif) receptor 3	0.011
Sertad2	SERTA domain containing 2	0.011
Sykb	spleen tyrosine kinase	0.011
Men1	multiple endocrine neoplasia 1	0.011
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.011
Tbx15	T-box 15	0.011
Adcy7	adenylate cyclase 7	0.011
Gna15	guanine nucleotide binding protein, alpha 15	0.011
Il2rb	interleukin 2 receptor, beta chain	0.011
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.011
Fkbp10	FK506 binding protein 10	0.011
Postn	periostin, osteoblast specific factor	0.011
Orm1	orosomucoid 1	0.011
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.011
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.011
Rnase4	ribonuclease, RNase A family 4	0.011
Cav1	caveolin 1, caveolae protein	0.011
Klf4	Kruppel-like factor 4 (gut)	0.011
Tnc	tenascin C	0.011
Lrp4	low density lipoprotein receptor-related protein 4	0.011	Mouse
Plcg1	phospholipase C, gamma 1	0.011
Taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B	0.011
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.011
Ncoa3	nuclear receptor coactivator 3	0.011
Sdc3	syndecan 3	0.011
Grpr	gastrin releasing peptide receptor	0.011
Gne	glucosamine	0.011
Ikzf3	IKAROS family zinc finger 3	0.011
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.011
Timp2	tissue inhibitor of metalloproteinase 2	0.011
Ids	iduronate 2-sulfatase	0.011
Bmp10	bone morphogenetic protein 10	0.010
Plat	plasminogen activator, tissue	0.010
Fyb	FYN binding protein	0.010
Hck	hemopoietic cell kinase	0.010	Mouse
F5	coagulation factor V	0.010
Npr2	natriuretic peptide receptor 2	0.010
Mesdc2	mesoderm development candidate 2	0.010
Plin5	perilipin 5	0.010
Col6a1	collagen, type VI, alpha 1	0.010
Ppard	peroxisome proliferator activator receptor delta	0.010
En1	engrailed 1	0.010
Wisp1	WNT1 inducible signaling pathway protein 1	0.010	Mouse
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.010
Alb	albumin	0.010
Dll1	delta-like 1 (Drosophila)	0.010
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.010