IMP
Process View
fatty acid beta oxidation
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "fatty acid beta oxidation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Acaa2 | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 0.997 | Rat | |
| Acadm | acyl-Coenzyme A dehydrogenase, medium chain | 0.995 | ||
| Etfa | electron transferring flavoprotein, alpha polypeptide | 0.994 | ||
| Lep | leptin | 0.970 | ||
| Ech1 | enoyl coenzyme A hydratase 1, peroxisomal | 0.955 | ||
| Eci2 | enoyl-Coenzyme A delta isomerase 2 | 0.928 | Rat | |
| Etfdh | electron transferring flavoprotein, dehydrogenase | 0.927 | ||
| Hadh | hydroxyacyl-Coenzyme A dehydrogenase | 0.906 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.871 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.769 | Mouse | |
| Slc25a20 | solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 | 0.765 | ||
| Decr1 | 2,4-dienoyl CoA reductase 1, mitochondrial | 0.742 | Human | |
| Hsd17b4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.740 | ||
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.672 | Rat | |
| Hsdl2 | hydroxysteroid dehydrogenase like 2 | 0.666 | ||
| Scp2 | sterol carrier protein 2, liver | 0.582 | ||
| Lepr | leptin receptor | 0.575 | ||
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.564 | Mouse | |
| Retsat | retinol saturase (all trans retinol 13,14 reductase) | 0.461 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.440 | ||
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.393 | Mouse | |
| Phyh | phytanoyl-CoA hydroxylase | 0.375 | ||
| C1qc | complement component 1, q subcomponent, C chain | 0.371 | Mouse | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.319 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.274 | ||
| Insr | insulin receptor | 0.257 | ||
| Cidec | cell death-inducing DFFA-like effector c | 0.213 | ||
| Acat1 | acetyl-Coenzyme A acetyltransferase 1 | 0.206 | ||
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.203 | ||
| Dhrs4 | dehydrogenase/reductase (SDR family) member 4 | 0.201 | ||
| Hadha | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 0.194 | ||
| Abcd3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.183 | Human Mouse | |
| Etfb | electron transferring flavoprotein, beta polypeptide | 0.181 | ||
| Cav1 | caveolin 1, caveolae protein | 0.170 | ||
| Acaa1b | acetyl-Coenzyme A acyltransferase 1B | 0.162 | ||
| Hibch | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 0.155 | ||
| Pccb | propionyl Coenzyme A carboxylase, beta polypeptide | 0.143 | ||
| Acadl | acyl-Coenzyme A dehydrogenase, long-chain | 0.142 | ||
| Ghr | growth hormone receptor | 0.138 | ||
| Hadhb | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 0.134 | Rat | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.126 | ||
| Plin1 | perilipin 1 | 0.107 | ||
| Acox1 | acyl-Coenzyme A oxidase 1, palmitoyl | 0.105 | Human | |
| Cpt2 | carnitine palmitoyltransferase 2 | 0.101 | ||
| Suclg2 | succinate-Coenzyme A ligase, GDP-forming, beta subunit | 0.099 | ||
| Ephx2 | epoxide hydrolase 2, cytoplasmic | 0.096 | ||
| Lipe | lipase, hormone sensitive | 0.095 | ||
| Ehhadh | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 0.090 | ||
| Acad11 | acyl-Coenzyme A dehydrogenase family, member 11 | 0.089 | ||
| Irs2 | insulin receptor substrate 2 | 0.088 | Human | |
| Chpt1 | choline phosphotransferase 1 | 0.086 | ||
| Cmbl | carboxymethylenebutenolidase-like (Pseudomonas) | 0.084 | ||
| Eci1 | enoyl-Coenzyme A delta isomerase 1 | 0.080 | ||
| Ak3 | adenylate kinase 3 | 0.079 | ||
| Rab9 | RAB9, member RAS oncogene family | 0.076 | ||
| Aldh9a1 | aldehyde dehydrogenase 9, subfamily A1 | 0.072 | ||
| Rxra | retinoid X receptor alpha | 0.071 | ||
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.071 | ||
| Bckdha | branched chain ketoacid dehydrogenase E1, alpha polypeptide | 0.070 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.066 | ||
| Pxmp4 | peroxisomal membrane protein 4 | 0.064 | ||
| Ppara | peroxisome proliferator activated receptor alpha | 0.060 | Mouse | |
| Acot1 | acyl-CoA thioesterase 1 | 0.059 | ||
| Pcx | pyruvate carboxylase | 0.059 | ||
| Acsl1 | acyl-CoA synthetase long-chain family member 1 | 0.057 | ||
| Ly86 | lymphocyte antigen 86 | 0.055 | ||
| Sqstm1 | sequestosome 1 | 0.053 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.052 | ||
| Agpat2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 0.051 | ||
| 4931406C07Rik | RIKEN cDNA 4931406C07 gene | 0.051 | ||
| Adipor2 | adiponectin receptor 2 | 0.050 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.048 | ||
| Mccc1 | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 0.048 | ||
| Gpam | glycerol-3-phosphate acyltransferase, mitochondrial | 0.048 | ||
| Mosc2 | MOCO sulphurase C-terminal domain containing 2 | 0.047 | ||
| Vegfa | vascular endothelial growth factor A | 0.047 | ||
| Cbr4 | carbonyl reductase 4 | 0.046 | ||
| Abhd5 | abhydrolase domain containing 5 | 0.043 | ||
| Ulk1 | Unc-51 like kinase 1 (C. elegans) | 0.041 | ||
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.040 | ||
| Pmpcb | peptidase (mitochondrial processing) beta | 0.040 | ||
| Cat | catalase | 0.040 | ||
| Rxrg | retinoid X receptor gamma | 0.039 | ||
| Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.039 | Yeast | |
| Kl | klotho | 0.039 | ||
| Ctss | cathepsin S | 0.039 | ||
| H2-Aa | histocompatibility 2, class II antigen A, alpha | 0.039 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.038 | ||
| Gpd1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | 0.038 | ||
| Apoe | apolipoprotein E | 0.037 | ||
| Lpin1 | lipin 1 | 0.036 | ||
| D19Wsu162e | DNA segment, Chr 19, Wayne State University 162, expressed | 0.036 | ||
| Crat | carnitine acetyltransferase | 0.036 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.035 | ||
| Acads | acyl-Coenzyme A dehydrogenase, short chain | 0.035 | Rat | |
| Aif1 | allograft inflammatory factor 1 | 0.035 | ||
| Lonp2 | lon peptidase 2, peroxisomal | 0.034 | Human | |
| Mut | methylmalonyl-Coenzyme A mutase | 0.031 | ||
| Mrc1 | mannose receptor, C type 1 | 0.031 | ||
| Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 0.031 | ||
| Npc1 | Niemann Pick type C1 | 0.030 | ||
| Pts | 6-pyruvoyl-tetrahydropterin synthase | 0.030 | ||
| Acadvl | acyl-Coenzyme A dehydrogenase, very long chain | 0.028 | ||
| Hsd17b10 | hydroxysteroid (17-beta) dehydrogenase 10 | 0.028 | ||
| Pcyox1 | prenylcysteine oxidase 1 | 0.027 | ||
| Sdha | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.027 | ||
| Pex11a | peroxisomal biogenesis factor 11 alpha | 0.026 | ||
| Slc22a5 | solute carrier family 22 (organic cation transporter), member 5 | 0.026 | ||
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.025 | ||
| Adrb1 | adrenergic receptor, beta 1 | 0.025 | ||
| Entpd5 | ectonucleoside triphosphate diphosphohydrolase 5 | 0.025 | ||
| Por | P450 (cytochrome) oxidoreductase | 0.025 | ||
| 1300010F03Rik | RIKEN cDNA 1300010F03 gene | 0.024 | ||
| Mccc2 | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 0.024 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.024 | ||
| Hibadh | 3-hydroxyisobutyrate dehydrogenase | 0.024 | ||
| Mknk2 | MAP kinase-interacting serine/threonine kinase 2 | 0.024 | ||
| Ptgr2 | prostaglandin reductase 2 | 0.023 | ||
| Acot2 | acyl-CoA thioesterase 2 | 0.022 | ||
| Sik3 | SIK family kinase 3 | 0.022 | ||
| Cryz | crystallin, zeta | 0.022 | ||
| Pex5 | peroxisomal biogenesis factor 5 | 0.022 | ||
| Npy1r | neuropeptide Y receptor Y1 | 0.022 | ||
| Apoa1 | apolipoprotein A-I | 0.022 | ||
| Plin4 | perilipin 4 | 0.022 | ||
| Idh2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.021 | Yeast | |
| Gstz1 | glutathione transferase zeta 1 (maleylacetoacetate isomerase) | 0.021 | ||
| Slc25a11 | solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 | 0.020 | ||
| Clybl | citrate lyase beta like | 0.020 | ||
| Nrxn1 | neurexin I | 0.020 | ||
| Gcgr | glucagon receptor | 0.020 | ||
| Syt7 | synaptotagmin VII | 0.020 | ||
| Ins2 | insulin II | 0.019 | ||
| Aco1 | aconitase 1 | 0.019 | ||
| Rdh16 | retinol dehydrogenase 16 | 0.019 | ||
| Gata6 | GATA binding protein 6 | 0.019 | ||
| Aifm1 | apoptosis-inducing factor, mitochondrion-associated 1 | 0.018 | ||
| 1110002B05Rik | RIKEN cDNA 1110002B05 gene | 0.018 | ||
| Ahsg | alpha-2-HS-glycoprotein | 0.018 | ||
| Neurog3 | neurogenin 3 | 0.018 | ||
| Apoc1 | apolipoprotein C-I | 0.018 | ||
| Pld4 | phospholipase D family, member 4 | 0.018 | ||
| Car3 | carbonic anhydrase 3 | 0.018 | ||
| Hacl1 | 2-hydroxyacyl-CoA lyase 1 | 0.018 | ||
| Aldh6a1 | aldehyde dehydrogenase family 6, subfamily A1 | 0.017 | ||
| Tmem135 | transmembrane protein 135 | 0.017 | ||
| Hint2 | histidine triad nucleotide binding protein 2 | 0.017 | ||
| Irs1 | insulin receptor substrate 1 | 0.017 | Human | |
| Hmgcs1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 0.017 | ||
| Aldob | aldolase B, fructose-bisphosphate | 0.017 | ||
| Lipa | lysosomal acid lipase A | 0.016 | ||
| Apoc4 | apolipoprotein C-IV | 0.016 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.016 | ||
| Gna12 | guanine nucleotide binding protein, alpha 12 | 0.016 | ||
| Ebf3 | early B-cell factor 3 | 0.016 | ||
| Zfand6 | zinc finger, AN1-type domain 6 | 0.016 | ||
| Dgat2 | diacylglycerol O-acyltransferase 2 | 0.016 | ||
| Lmna | lamin A | 0.015 | ||
| Smpd2 | sphingomyelin phosphodiesterase 2, neutral | 0.015 | ||
| Fabp1 | fatty acid binding protein 1, liver | 0.015 | Rat | |
| Lyz1 | lysozyme 1 | 0.015 | ||
| Acly | ATP citrate lyase | 0.015 | ||
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.015 | ||
| Nhlh2 | nescient helix loop helix 2 | 0.015 | ||
| Ces1d | carboxylesterase 1D | 0.015 | ||
| Mocs2 | molybdenum cofactor synthesis 2 | 0.015 | ||
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.015 | ||
| G0s2 | G0/G1 switch gene 2 | 0.015 | ||
| Pipox | pipecolic acid oxidase | 0.015 | ||
| Fbxo8 | F-box protein 8 | 0.015 | ||
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.014 | ||
| Akt2 | thymoma viral proto-oncogene 2 | 0.014 | Human | |
| Acsm3 | acyl-CoA synthetase medium-chain family member 3 | 0.014 | ||
| Optn | optineurin | 0.014 | ||
| Hgd | homogentisate 1, 2-dioxygenase | 0.014 | ||
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.014 | ||
| Gstk1 | glutathione S-transferase kappa 1 | 0.014 | ||
| Ormdl1 | ORM1-like 1 (S. cerevisiae) | 0.013 | ||
| Trabd | TraB domain containing | 0.013 | ||
| Mafb | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) | 0.013 | ||
| Bckdhb | branched chain ketoacid dehydrogenase E1, beta polypeptide | 0.013 | ||
| Cplx1 | complexin 1 | 0.013 | ||
| Glud1 | glutamate dehydrogenase 1 | 0.013 | ||
| C3 | complement component 3 | 0.013 | ||
| Dram2 | VDNA-damage regulated autophagy modulator 2 | 0.013 | ||
| Acaa1a | acetyl-Coenzyme A acyltransferase 1A | 0.013 | Rat | |
| Fcgrt | Fc receptor, IgG, alpha chain transporter | 0.013 | ||
| Sult1d1 | sulfotransferase family 1D, member 1 | 0.013 | ||
| Mpv17 | MpV17 mitochondrial inner membrane protein | 0.013 | ||
| Aldh4a1 | aldehyde dehydrogenase 4 family, member A1 | 0.013 | ||
| Gucy2e | guanylate cyclase 2e | 0.012 | ||
| Hsd17b11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.012 | ||
| Igf1 | insulin-like growth factor 1 | 0.012 | ||
| Adrb3 | adrenergic receptor, beta 3 | 0.012 | ||
| Iars2 | isoleucine-tRNA synthetase 2, mitochondrial | 0.012 | ||
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.012 | ||
| Vstm2b | V-set and transmembrane domain containing 2B | 0.012 | ||
| Tpmt | thiopurine methyltransferase | 0.012 | ||
| Iyd | iodotyrosine deiodinase | 0.012 | ||
| Foxo1 | forkhead box O1 | 0.012 | ||
| Cyp3a25 | cytochrome P450, family 3, subfamily a, polypeptide 25 | 0.012 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.012 | ||
| Lgals4 | lectin, galactose binding, soluble 4 | 0.012 | ||
| Prlr | prolactin receptor | 0.012 | ||
| 2310001A20Rik | RIKEN cDNA 2310001A20 gene | 0.012 | ||
| Nr1h3 | nuclear receptor subfamily 1, group H, member 3 | 0.012 | ||
| Adh5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.012 | ||
| Hmgcl | 3-hydroxy-3-methylglutaryl-Coenzyme A lyase | 0.012 | ||
| Dgcr2 | DiGeorge syndrome critical region gene 2 | 0.012 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.011 | ||
| Sult1b1 | sulfotransferase family 1B, member 1 | 0.011 | ||
| Azgp1 | alpha-2-glycoprotein 1, zinc | 0.011 | ||
| Sema5b | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | 0.011 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.011 | ||
| Nit2 | nitrilase family, member 2 | 0.011 | ||
| Rarg | retinoic acid receptor, gamma | 0.011 | ||
| Ces1f | carboxylesterase 1F | 0.011 | ||
| Pgm2 | phosphoglucomutase 2 | 0.011 | ||
| Klc4 | kinesin light chain 4 | 0.011 | ||
| Mark2 | MAP/microtubule affinity-regulating kinase 2 | 0.011 | ||
| Capn1 | calpain 1 | 0.011 | ||
| Cidea | cell death-inducing DNA fragmentation factor, alpha subunit-like effector A | 0.011 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.011 | ||
| Abcc2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.011 | ||
| Cfp | complement factor properdin | 0.011 | ||
| Lyrm5 | LYR motif containing 5 | 0.011 | ||
| Cfd | complement factor D (adipsin) | 0.011 | ||
| C8g | complement component 8, gamma polypeptide | 0.011 | ||
| Hcn1 | hyperpolarization-activated, cyclic nucleotide-gated K+ 1 | 0.011 | ||
| Nr1i2 | nuclear receptor subfamily 1, group I, member 2 | 0.011 | Mouse | |
| H1f0 | H1 histone family, member 0 | 0.011 | ||
| BC013529 | cDNA sequence BC013529 | 0.011 | ||
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.010 | ||
| Nr1h4 | nuclear receptor subfamily 1, group H, member 4 | 0.010 | Mouse | |
| Kiss1r | KISS1 receptor | 0.010 | ||
| Cd36 | CD36 antigen | 0.010 | ||
| Abcg5 | ATP-binding cassette, sub-family G (WHITE), member 5 | 0.010 | ||
| Marveld1 | MARVEL (membrane-associating) domain containing 1 | 0.010 | ||
| Apoa4 | apolipoprotein A-IV | 0.010 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.010 | ||
| Lyz2 | lysozyme 2 | 0.010 | ||
| Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.010 |