IMP: Integrative Multi-species Prediction

Mus musculus

21 genes annotated in mouse

lytic vacuole organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lytic vacuole organization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "lytic vacuole organization" (in gray)

Name	Description	Probability	Func Analog Organism
Dpp7	dipeptidylpeptidase 7	0.991
Hexb	hexosaminidase B	0.986
Hexa	hexosaminidase A	0.972
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.971
Idua	iduronidase, alpha-L-	0.815
Mitf	microphthalmia-associated transcription factor	0.791
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.735
Lyst	lysosomal trafficking regulator	0.708
Apoe	apolipoprotein E	0.600
Npc1	Niemann Pick type C1	0.574
a	nonagouti	0.456
Rab27a	RAB27A, member RAS oncogene family	0.447
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.373
Gaa	glucosidase, alpha, acid	0.343
Naga	N-acetyl galactosaminidase, alpha	0.338
Gusb	glucuronidase, beta	0.312
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.284
Renbp	renin binding protein	0.255
Pld3	phospholipase D family, member 3	0.242
Myo6	myosin VI	0.225
Ctsa	cathepsin A	0.218
Dscr3	Down syndrome critical region gene 3	0.202
Man2b1	mannosidase 2, alpha B1	0.199
Mfsd1	major facilitator superfamily domain containing 1	0.189
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.186
Itgb5	integrin beta 5	0.179
Ush1g	Usher syndrome 1G homolog (human)	0.166
Naglu	alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)	0.157
Adam17	a disintegrin and metallopeptidase domain 17	0.153
Wdr81	WD repeat domain 81	0.136
Lamp1	lysosomal-associated membrane protein 1	0.132
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.120	Mouse
Gba	glucosidase, beta, acid	0.120
Coro1b	coronin, actin binding protein 1B	0.117
Neu1	neuraminidase 1	0.115
Gns	glucosamine (N-acetyl)-6-sulfatase	0.115
Sgpl1	sphingosine phosphate lyase 1	0.108
Pldn	pallidin	0.102
Hps6	Hermansky-Pudlak syndrome 6	0.102
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.101
Glb1	galactosidase, beta 1	0.098
Tpra1	transmembrane protein, adipocyte asscociated 1	0.097
Epn1	epsin 1	0.096
Arsa	arylsulfatase A	0.096
Mpv17	MpV17 mitochondrial inner membrane protein	0.094
Asah1	N-acylsphingosine amidohydrolase 1	0.088
Arsb	arylsulfatase B	0.085
Tcn2	transcobalamin 2	0.082
Il10rb	interleukin 10 receptor, beta	0.079
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.078
Pmel	premelanosome protein	0.078
Gopc	golgi associated PDZ and coiled-coil motif containing	0.075
Ctsz	cathepsin Z	0.075
Ctsd	cathepsin D	0.075
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.075
Pold4	polymerase (DNA-directed), delta 4	0.071
Siae	sialic acid acetylesterase	0.070
Galns	galactosamine (N-acetyl)-6-sulfate sulfatase	0.063
Yipf3	Yip1 domain family, member 3	0.062
Tpp1	tripeptidyl peptidase I	0.060
Lgals8	lectin, galactose binding, soluble 8	0.059
Hs1bp3	HCLS1 binding protein 3	0.058
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.057
Mcoln1	mucolipin 1	0.056	Worm
Rora	RAR-related orphan receptor alpha	0.055
Mertk	c-mer proto-oncogene tyrosine kinase	0.055
Uap1l1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.054
Psap	prosaposin	0.050
Zbtb24	zinc finger and BTB domain containing 24	0.050
4833420G17Rik	RIKEN cDNA 4833420G17 gene	0.049
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.048	Human
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.048	Mouse
Atp13a2	ATPase type 13A2	0.047
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.046
Gm2a	GM2 ganglioside activator protein	0.046
Pik3r2	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)	0.046
Txndc16	thioredoxin domain containing 16	0.045
Lamtor3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.044
Ppt1	palmitoyl-protein thioesterase 1	0.044
Manba	mannosidase, beta A, lysosomal	0.043
Stard3	START domain containing 3	0.043
Spsb2	splA/ryanodine receptor domain and SOCS box containing 2	0.042
Unc93b1	unc-93 homolog B1 (C. elegans)	0.042
Cln3	ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	0.042
Slc35c2	solute carrier family 35, member C2	0.042
Lipa	lysosomal acid lipase A	0.041
Gnpda1	glucosamine-6-phosphate deaminase 1	0.041
Man2b2	mannosidase 2, alpha B2	0.040
Npc2	Niemann Pick type C2	0.039
Zfp187	zinc finger protein 187	0.038
Mlph	melanophilin	0.038
Sirpa	signal-regulatory protein alpha	0.038
Itm2c	integral membrane protein 2C	0.038
Sat1	spermidine/spermine N1-acetyl transferase 1	0.037
Dram2	VDNA-damage regulated autophagy modulator 2	0.037
Pex6	peroxisomal biogenesis factor 6	0.037
Tex264	testis expressed gene 264	0.037
Lrp1	low density lipoprotein receptor-related protein 1	0.036
Pla2g15	phospholipase A2, group XV	0.036
AW549877	expressed sequence AW549877	0.036
Tom1	target of myb1 homolog (chicken)	0.035
Amdhd2	amidohydrolase domain containing 2	0.034
Lgmn	legumain	0.034
Ush1c	Usher syndrome 1C homolog (human)	0.033
Heatr7a	HEAT repeat containing 7A	0.033
S1pr3	sphingosine-1-phosphate receptor 3	0.033
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.033
Pigs	phosphatidylinositol glycan anchor biosynthesis, class S	0.032
Ccni	cyclin I	0.032
Rbl2	retinoblastoma-like 2	0.031
Ghdc	GH3 domain containing	0.031
Hps3	Hermansky-Pudlak syndrome 3 homolog (human)	0.031
Lrpap1	low density lipoprotein receptor-related protein associated protein 1	0.030
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.030
Ppt2	palmitoyl-protein thioesterase 2	0.029	Mouse
Vps41	vacuolar protein sorting 41 (yeast)	0.029
Gm12942	predicted gene 12942	0.029
Klc4	kinesin light chain 4	0.029
Cyp4f13	cytochrome P450, family 4, subfamily f, polypeptide 13	0.029
Ctns	cystinosis, nephropathic	0.029
Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.028
AI413582	expressed sequence AI413582	0.028
Soat1	sterol O-acyltransferase 1	0.028
Ikbkb	inhibitor of kappaB kinase beta	0.028
Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	0.028
Clcn7	chloride channel 7	0.027
Nagk	N-acetylglucosamine kinase	0.027
Vim	vimentin	0.026
Cx3cr1	chemokine (C-X3-C) receptor 1	0.026
1600012H06Rik	RIKEN cDNA 1600012H06 gene	0.026
Mapre3	microtubule-associated protein, RP/EB family, member 3	0.025
Edem2	ER degradation enhancer, mannosidase alpha-like 2	0.024
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.024	Worm
2310044H10Rik	RIKEN cDNA 2310044H10 gene	0.024
Pnrc2	proline-rich nuclear receptor coactivator 2	0.024
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.024	Mouse
Tgfbr1	transforming growth factor, beta receptor I	0.024
Hgsnat	heparan-alpha-glucosaminide N-acetyltransferase	0.023
Fxc1	fractured callus expressed transcript 1	0.023
2210016L21Rik	RIKEN cDNA 2210016L21 gene	0.023
Daglb	diacylglycerol lipase, beta	0.023
Ap1g2	adaptor protein complex AP-1, gamma 2 subunit	0.023
Tspyl1	testis-specific protein, Y-encoded-like 1	0.022
Igsf8	immunoglobulin superfamily, member 8	0.022
Stxbp2	syntaxin binding protein 2	0.022
Tmem86a	transmembrane protein 86A	0.022
Cno	cappuccino	0.022
Def8	differentially expressed in FDCP 8	0.022
Paqr7	progestin and adipoQ receptor family member VII	0.021
Bckdk	branched chain ketoacid dehydrogenase kinase	0.021
Grn	granulin	0.021
5033414D02Rik	RIKEN cDNA 5033414D02 gene	0.021
ORF61	open reading frame 61	0.021
Tbxas1	thromboxane A synthase 1, platelet	0.020
Slc24a6	solute carrier family 24 (sodium/potassium/calcium exchanger), member 6	0.020
Pltp	phospholipid transfer protein	0.020
Slc7a8	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8	0.020
Dtnbp1	dystrobrevin binding protein 1	0.020
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.020
Snap23	synaptosomal-associated protein 23	0.019
Adam10	a disintegrin and metallopeptidase domain 10	0.019
Tmem150a	transmembrane protein 150A	0.019
Galc	galactosylceramidase	0.019
S1pr2	sphingosine-1-phosphate receptor 2	0.019
Rab4b	RAB4B, member RAS oncogene family	0.019
B3galt4	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4	0.019
Fundc1	FUN14 domain containing 1	0.019
G6pc3	glucose 6 phosphatase, catalytic, 3	0.019
Tep1	telomerase associated protein 1	0.019
Phka2	phosphorylase kinase alpha 2	0.019
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.018
BC026585	cDNA sequence BC026585	0.018
Agtrap	angiotensin II, type I receptor-associated protein	0.018
Galk2	galactokinase 2	0.018
Ccng2	cyclin G2	0.018
Fam134a	family with sequence similarity 134, member A	0.018
Mapk9	mitogen-activated protein kinase 9	0.018
Osbpl9	oxysterol binding protein-like 9	0.018
Pigt	phosphatidylinositol glycan anchor biosynthesis, class T	0.018
Sel1l	sel-1 suppressor of lin-12-like (C. elegans)	0.018
Vps18	vacuolar protein sorting 18 (yeast)	0.017
Flcn	folliculin	0.017
Mtmr1	myotubularin related protein 1	0.017
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.017
Slc50a1	solute carrier family 50 (sugar transporter), member 1	0.017
BC017643	cDNA sequence BC017643	0.017
Cept1	choline/ethanolaminephosphotransferase 1	0.017
Nhlrc3	NHL repeat containing 3	0.017
Man1a	mannosidase 1, alpha	0.016
Mettl7a1	methyltransferase like 7A1	0.016
Eif4a2	eukaryotic translation initiation factor 4A2	0.016
Anpep	alanyl (membrane) aminopeptidase	0.016
Cd68	CD68 antigen	0.016
Ctbs	chitobiase, di-N-acetyl-	0.016
Tbc1d22a	TBC1 domain family, member 22a	0.016
Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.016
Scpep1	serine carboxypeptidase 1	0.016
Kit	kit oncogene	0.015
Gla	galactosidase, alpha	0.015
Btd	biotinidase	0.015
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.015
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.015
Phf1	PHD finger protein 1	0.015
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.015
Pycard	PYD and CARD domain containing	0.015
Abca2	ATP-binding cassette, sub-family A (ABC1), member 2	0.014
Enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.014
Mylip	myosin regulatory light chain interacting protein	0.014
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.014
Fbp2	fructose bisphosphatase 2	0.014
Gdf15	growth differentiation factor 15	0.014
Fkbp15	FK506 binding protein 15	0.014
Araf	v-raf murine sarcoma 3611 viral oncogene homolog	0.014
Pdzk1ip1	PDZK1 interacting protein 1	0.014
Clta	clathrin, light polypeptide (Lca)	0.014
Tyk2	tyrosine kinase 2	0.014
Wbp2	WW domain binding protein 2	0.014
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.014
Sumf1	sulfatase modifying factor 1	0.014
Inpp5k	inositol polyphosphate 5-phosphatase K	0.014
Fbxl3	F-box and leucine-rich repeat protein 3	0.014
Snta1	syntrophin, acidic 1	0.014
Hrh2	histamine receptor H2	0.014
Tmem179b	transmembrane protein 179B	0.014
Slc17a5	solute carrier family 17 (anion/sugar transporter), member 5	0.014
Kif3b	kinesin family member 3B	0.014
Xylt2	xylosyltransferase II	0.013
Slc31a2	solute carrier family 31, member 2	0.013
Gpr137b	G protein-coupled receptor 137B	0.013
Inpp4a	inositol polyphosphate-4-phosphatase, type I	0.013
Bri3	brain protein I3	0.013
Fzd8	frizzled homolog 8 (Drosophila)	0.013
Spg21	spastic paraplegia 21 homolog (human)	0.013
Ctsh	cathepsin H	0.013
Rnf111	ring finger 111	0.013
Tpd52	tumor protein D52	0.013
Ids	iduronate 2-sulfatase	0.013
Arf3	ADP-ribosylation factor 3	0.013
Fcgrt	Fc receptor, IgG, alpha chain transporter	0.013
Nrip2	nuclear receptor interacting protein 2	0.013
Snx14	sorting nexin 14	0.013
Stx7	syntaxin 7	0.013
Myo5a	myosin VA	0.013
Ephx1	epoxide hydrolase 1, microsomal	0.013
Pnpla7	patatin-like phospholipase domain containing 7	0.012
Mogat2	monoacylglycerol O-acyltransferase 2	0.012
D6Wsu116e	DNA segment, Chr 6, Wayne State University 116, expressed	0.012
C330006K01Rik	RIKEN cDNA C330006K01 gene	0.012
Usp8	ubiquitin specific peptidase 8	0.012
Zfp524	zinc finger protein 524	0.012
Slc25a45	solute carrier family 25, member 45	0.012
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.012
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.012
Taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B	0.012
Rab7l1	RAB7, member RAS oncogene family-like 1	0.012
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.012
Tbxa2r	thromboxane A2 receptor	0.012
Pld2	phospholipase D2	0.012
Cln6	ceroid-lipofuscinosis, neuronal 6	0.012
Rab5b	RAB5B, member RAS oncogene family	0.012
Tmc6	transmembrane channel-like gene family 6	0.012
Zfand6	zinc finger, AN1-type domain 6	0.012
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.012
Slc9a8	solute carrier family 9 (sodium/hydrogen exchanger), member 8	0.012
Tbc1d23	TBC1 domain family, member 23	0.012
Ergic3	ERGIC and golgi 3	0.012
Sntb1	syntrophin, basic 1	0.012
Hsd17b11	hydroxysteroid (17-beta) dehydrogenase 11	0.012
Plekhb1	pleckstrin homology domain containing, family B (evectins) member 1	0.012
Iah1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	0.012
Khk	ketohexokinase	0.012
Uvrag	UV radiation resistance associated gene	0.012
Prkcb	protein kinase C, beta	0.012
Ubr1	ubiquitin protein ligase E3 component n-recognin 1	0.012
Inppl1	inositol polyphosphate phosphatase-like 1	0.012
Map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.011
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.011
Fndc3a	fibronectin type III domain containing 3A	0.011
Atp2c1	ATPase, Ca++-sequestering	0.011
Rnf130	ring finger protein 130	0.011
Fuca1	fucosidase, alpha-L- 1, tissue	0.011
Plcb2	phospholipase C, beta 2	0.011
Rassf2	Ras association (RalGDS/AF-6) domain family member 2	0.011
Eef2	eukaryotic translation elongation factor 2	0.011
Acp5	acid phosphatase 5, tartrate resistant	0.011
Ppm1m	protein phosphatase 1M	0.011
Epha1	Eph receptor A1	0.011
1110003E01Rik	RIKEN cDNA 1110003E01 gene	0.011
Nucb1	nucleobindin 1	0.011
St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	0.011
Slc38a6	solute carrier family 38, member 6	0.011
Uckl1	uridine-cytidine kinase 1-like 1	0.011
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.011
Cln5	ceroid-lipofuscinosis, neuronal 5	0.011
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.011
Fbxl8	F-box and leucine-rich repeat protein 8	0.011
Slc38a7	solute carrier family 38, member 7	0.011
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.011
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.011
Tmed8	transmembrane emp24 domain containing 8	0.011
Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	0.011
Cyba	cytochrome b-245, alpha polypeptide	0.011
Clk1	CDC-like kinase 1	0.011
Slc2a8	solute carrier family 2, (facilitated glucose transporter), member 8	0.011
Pqlc2	PQ loop repeat containing 2	0.011
Slc17a9	solute carrier family 17, member 9	0.011
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.011
Alg1	asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)	0.011
Plxnb2	plexin B2	0.011
Dhrs3	dehydrogenase/reductase (SDR family) member 3	0.011
Slc12a9	solute carrier family 12 (potassium/chloride transporters), member 9	0.011
Fam3a	family with sequence similarity 3, member A	0.011
Rogdi	rogdi homolog (Drosophila)	0.010
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	0.010
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.010
Dnase1l1	deoxyribonuclease 1-like 1	0.010
Guca1a	guanylate cyclase activator 1a (retina)	0.010
Kcp	kielin/chordin-like protein	0.010
Nt5e	5' nucleotidase, ecto	0.010
Slc39a13	solute carrier family 39 (metal ion transporter), member 13	0.010
Aldh3b1	aldehyde dehydrogenase 3 family, member B1	0.010
Mfap4	microfibrillar-associated protein 4	0.010
Fbxw4	F-box and WD-40 domain protein 4	0.010
Xiap	X-linked inhibitor of apoptosis	0.010
Ccpg1	cell cycle progression 1	0.010
Galnt4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4	0.010
Hoxb4	homeobox B4	0.010
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.010