IMP: Integrative Multi-species Prediction

Mus musculus

15 genes annotated in mouse

Multi-species View

positive regulation of t cell mediated cytotoxicity

GO:0001916

Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of t cell mediated cytotoxicity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of t cell mediated cytotoxicity" (in gray)

Name	Description	Probability	Func Analog Organism
B2m	beta-2 microglobulin	1.000
H2-K1	histocompatibility 2, K1, K region	1.000
Tapbp	TAP binding protein	1.000
H2-D1	histocompatibility 2, D region locus 1	1.000
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	1.000
H2-Q7	histocompatibility 2, Q region locus 7	1.000
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	1.000	Mouse
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	1.000
Fyn	Fyn proto-oncogene	1.000
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	1.000
Pnp2	purine-nucleoside phosphorylase 2	0.999
Il2rg	interleukin 2 receptor, gamma chain	0.985
Lck	lymphocyte protein tyrosine kinase	0.981
Tcra	T-cell receptor alpha chain	0.980
Lat	linker for activation of T cells	0.907
Cd247	CD247 antigen	0.894
Casp8	caspase 8	0.885
H2-Q6	histocompatibility 2, Q region locus 6	0.879	Mouse Rat
H2-Q8	histocompatibility 2, Q region locus 8	0.753
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.654
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.622
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.569
Gbp2	guanylate binding protein 2	0.550
Il23a	interleukin 23, alpha subunit p19	0.520
Cp	ceruloplasmin	0.518
Fas	Fas (TNF receptor superfamily member 6)	0.514
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.511
Gbp7	guanylate binding protein 7	0.463
H2-M3	histocompatibility 2, M region locus 3	0.383
Stat1	signal transducer and activator of transcription 1	0.351
Sh2d2a	SH2 domain protein 2A	0.341
Shisa5	shisa homolog 5 (Xenopus laevis)	0.311
Ptprc	protein tyrosine phosphatase, receptor type, C	0.300
Irf1	interferon regulatory factor 1	0.247
H2-T10	histocompatibility 2, T region locus 10	0.242	Mouse
Il10rb	interleukin 10 receptor, beta	0.230
Dnm2	dynamin 2	0.226
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.218
Ikzf1	IKAROS family zinc finger 1	0.217
Ciita	class II transactivator	0.209
Nmi	N-myc (and STAT) interactor	0.199
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.185
Psme1	proteasome (prosome, macropain) 28 subunit, alpha	0.178
Rap1b	RAS related protein 1b	0.177
H2-T18	histocompatibility 2, T region locus 18	0.177
Psme2	proteasome (prosome, macropain) 28 subunit, beta	0.173
H2-Bl	histocompatibility 2, blastocyst	0.153
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.148	Mouse
Bst2	bone marrow stromal cell antigen 2	0.143
Itm2b	integral membrane protein 2B	0.136
Sp100	nuclear antigen Sp100	0.130
Parp14	poly (ADP-ribose) polymerase family, member 14	0.130
Gbp3	guanylate binding protein 3	0.126
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.126	Mouse
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.117
Trim21	tripartite motif-containing 21	0.115
Il12b	interleukin 12b	0.114
C3	complement component 3	0.112
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.090
Ghrl	ghrelin	0.089
Pon3	paraoxonase 3	0.078
Tapbpl	TAP binding protein-like	0.078
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.071
Grb2	growth factor receptor bound protein 2	0.069
H2-Q5	histocompatibility 2, Q region locus 5	0.069
Tgtp2	T-cell specific GTPase 2	0.067
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.066	Mouse
Shc1	src homology 2 domain-containing transforming protein C1	0.065
AW112010	expressed sequence AW112010	0.057
Spry4	sprouty homolog 4 (Drosophila)	0.056
Ephx1	epoxide hydrolase 1, microsomal	0.056
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.055
Itk	IL2-inducible T-cell kinase	0.055
Ptafr	platelet-activating factor receptor	0.050
Skap2	src family associated phosphoprotein 2	0.049
Tnf	tumor necrosis factor	0.048
Ifi35	interferon-induced protein 35	0.046
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.044
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.043
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.043
Uba7	ubiquitin-like modifier activating enzyme 7	0.043
Ifi27l1	interferon, alpha-inducible protein 27 like 1	0.042
Ctsz	cathepsin Z	0.042
Ly6e	lymphocyte antigen 6 complex, locus E	0.041
Ccrl2	chemokine (C-C motif) receptor-like 2	0.040
C2	complement component 2 (within H-2S)	0.040
Il15	interleukin 15	0.039
Irgm2	immunity-related GTPase family M member 2	0.039
Cflar	CASP8 and FADD-like apoptosis regulator	0.038
5133401N09Rik	RIKEN cDNA 5133401N09 gene	0.038
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.037
Lgals8	lectin, galactose binding, soluble 8	0.037
Ctsc	cathepsin C	0.035
Gm2a	GM2 ganglioside activator protein	0.035
Vti1b	vesicle transport through interaction with t-SNAREs 1B homolog	0.034
Dnase1l1	deoxyribonuclease 1-like 1	0.034
Adora2a	adenosine A2a receptor	0.033
Chl1	cell adhesion molecule with homology to L1CAM	0.032
Cd302	CD302 antigen	0.032
H2-Q10	histocompatibility 2, Q region locus 10	0.032	Mouse Rat
Ctsh	cathepsin H	0.032
Ocm	oncomodulin	0.031
Apbh	androgen-binding protein eta	0.029
Ifi203	interferon activated gene 203	0.027
Stx4a	syntaxin 4A (placental)	0.026
H2-Q1	histocompatibility 2, Q region locus 1	0.025	Mouse Rat
Mgmt	O-6-methylguanine-DNA methyltransferase	0.025
Anxa4	annexin A4	0.025
Casp12	caspase 12	0.025
Pgcp	plasma glutamate carboxypeptidase	0.025
Ccr9	chemokine (C-C motif) receptor 9	0.025
Fut7	fucosyltransferase 7	0.025
Ptprn	protein tyrosine phosphatase, receptor type, N	0.024
Mcpt8	mast cell protease 8	0.024
Olfr93	olfactory receptor 93	0.024
Cbl	Casitas B-lineage lymphoma	0.024
Klf6	Kruppel-like factor 6	0.023
Epo	erythropoietin	0.023
Il15ra	interleukin 15 receptor, alpha chain	0.023
Dynlt1b	dynein light chain Tctex-type 1D	0.023
Flt3l	FMS-like tyrosine kinase 3 ligand	0.023
Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	0.022
Fcna	ficolin A	0.022
Sct	secretin	0.021
H2-T9	histocompatibility 2, T region locus 9	0.019
Mrap	melanocortin 2 receptor accessory protein	0.019
Trim30a	tripartite motif-containing 30A	0.019
Cd274	CD274 antigen	0.018
Xcl1	chemokine (C motif) ligand 1	0.018
Asah1	N-acylsphingosine amidohydrolase 1	0.018
Itgav	integrin alpha V	0.017
Gh	growth hormone	0.017
H2-Q2	histocompatibility 2, Q region locus 2	0.017
Gbp4	guanylate binding protein 4	0.017
Sry	sex determining region of Chr Y	0.017
Irgm1	immunity-related GTPase family M member 1	0.017
Dnase1l3	deoxyribonuclease 1-like 3	0.016
Cd4	CD4 antigen	0.016
Wipf1	WAS/WASL interacting protein family, member 1	0.016
H2-T23	histocompatibility 2, T region locus 23	0.016
H2-DMb1	histocompatibility 2, class II, locus Mb1	0.016
F7	coagulation factor VII	0.016
Casp6	caspase 6	0.016
Stom	stomatin	0.015
Cd40	CD40 antigen	0.015
Sntb1	syntrophin, basic 1	0.015
Rnase4	ribonuclease, RNase A family 4	0.015
H2-M2	histocompatibility 2, M region locus 2	0.015	Mouse
Igtp	interferon gamma induced GTPase	0.015
Gm8909	predicted gene 8909	0.015	Mouse Rat
Cd83	CD83 antigen	0.015
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.014
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.014
Irf8	interferon regulatory factor 8	0.014
Ctsa	cathepsin A	0.014
Gsdmd	gasdermin D	0.014
Hfe	hemochromatosis	0.014	Mouse
Csprs	component of Sp100-rs	0.014
Tubb2c	tubulin, beta 2C	0.014
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.014
Gdf15	growth differentiation factor 15	0.014
Rpl39	ribosomal protein L39	0.013
Cd209d	CD209d antigen	0.013
Cx3cr1	chemokine (C-X3-C) receptor 1	0.013
Cd38	CD38 antigen	0.013
Parp9	poly (ADP-ribose) polymerase family, member 9	0.013
Zfp36	zinc finger protein 36	0.012
Serpinf1	serine (or cysteine) peptidase inhibitor, clade F, member 1	0.012
Dynlt1f	dynein light chain Tctex-type 1F	0.012
Acp5	acid phosphatase 5, tartrate resistant	0.012
C1ra	complement component 1, r subcomponent A	0.012
Itga3	integrin alpha 3	0.011
Hamp	hepcidin antimicrobial peptide	0.011
Jak1	Janus kinase 1	0.011
4732456N10Rik	RIKEN cDNA 4732456N10 gene	0.011
Txnip	thioredoxin interacting protein	0.011
Krtap5-4	keratin associated protein 5-4	0.011
Snx10	sorting nexin 10	0.011
Egfl8	EGF-like domain 8	0.011
Zc3h3	zinc finger CCCH type containing 3	0.010
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.010
Cxcl5	chemokine (C-X-C motif) ligand 5	0.010
Cd36	CD36 antigen	0.010
Tmprss5	transmembrane protease, serine 5 (spinesin)	0.010
Tsx	testis specific X-linked gene	0.010
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.010
Dhrs3	dehydrogenase/reductase (SDR family) member 3	0.010