Process View
A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "telomere capping"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.999 | ||
Trp53 | transformation related protein 53 | 0.999 | ||
Lig4 | ligase IV, DNA, ATP-dependent | 0.961 | ||
Igh | immunoglobulin heavy chain complex | 0.953 | ||
Nbn | nibrin | 0.919 | ||
Acd | adrenocortical dysplasia | 0.903 | ||
Terf1 | telomeric repeat binding factor 1 | 0.736 | Mouse | |
Pola1 | polymerase (DNA directed), alpha 1 | 0.564 | ||
Brca1 | breast cancer 1 | 0.524 | ||
Dna2 | DNA replication helicase 2 homolog (yeast) | 0.428 | ||
Prim2 | DNA primase, p58 subunit | 0.418 | ||
Brca2 | breast cancer 2 | 0.402 | ||
Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.372 | ||
Mre11a | meiotic recombination 11 homolog A (S. cerevisiae) | 0.359 | Fly | |
Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.326 | ||
Atm | ataxia telangiectasia mutated homolog (human) | 0.317 | Fly | |
Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.307 | ||
Rad50 | RAD50 homolog (S. cerevisiae) | 0.266 | Fly | |
Msh2 | mutS homolog 2 (E. coli) | 0.197 | ||
Trp53bp1 | transformation related protein 53 binding protein 1 | 0.174 | ||
Mphosph9 | M-phase phosphoprotein 9 | 0.142 | ||
Wrn | Werner syndrome homolog (human) | 0.091 | ||
Mlh1 | mutL homolog 1 (E. coli) | 0.089 | ||
Tcra | T-cell receptor alpha chain | 0.079 | ||
Ints9 | integrator complex subunit 9 | 0.072 | ||
Rfc1 | replication factor C (activator 1) 1 | 0.070 | ||
Rnf8 | ring finger protein 8 | 0.054 | ||
Smn1 | survival motor neuron 1 | 0.049 | ||
Rag1 | recombination activating gene 1 | 0.046 | ||
Parp2 | poly (ADP-ribose) polymerase family, member 2 | 0.046 | ||
Ckap5 | cytoskeleton associated protein 5 | 0.043 | ||
Ikzf1 | IKAROS family zinc finger 1 | 0.042 | ||
Pot1a | protection of telomeres 1A | 0.041 | Mouse | |
Sin3a | transcriptional regulator, SIN3A (yeast) | 0.040 | ||
Xrcc5 | X-ray repair complementing defective repair in Chinese hamster cells 5 | 0.039 | ||
Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.037 | ||
Nfatc3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.036 | ||
Fancm | Fanconi anemia, complementation group M | 0.032 | ||
Zmym4 | zinc finger, MYM-type 4 | 0.032 | ||
Xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.032 | ||
Obfc1 | oligonucleotide/oligosaccharide-binding fold containing 1 | 0.031 | ||
Atr | ataxia telangiectasia and Rad3 related | 0.029 | ||
Card11 | caspase recruitment domain family, member 11 | 0.029 | ||
Mtf2 | metal response element binding transcription factor 2 | 0.028 | ||
Pou2f1 | POU domain, class 2, transcription factor 1 | 0.027 | ||
Zfp101 | zinc finger protein 101 | 0.027 | ||
Huwe1 | HECT, UBA and WWE domain containing 1 | 0.027 | ||
5830418K08Rik | RIKEN cDNA 5830418K08 gene | 0.026 | ||
Recql | RecQ protein-like | 0.026 | ||
Tpp1 | tripeptidyl peptidase I | 0.025 | ||
Rttn | rotatin | 0.025 | ||
Tcrb | T-cell receptor beta chain | 0.022 | ||
Gps2 | G protein pathway suppressor 2 | 0.021 | ||
Rbl1 | retinoblastoma-like 1 (p107) | 0.021 | ||
Tcrd | T-cell receptor delta chain | 0.020 | ||
Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.020 | ||
Etaa1 | Ewing's tumor-associated antigen 1 | 0.020 | ||
Smc6 | structural maintenance of chromosomes 6 | 0.018 | ||
Aqr | aquarius | 0.018 | ||
Lcp2 | lymphocyte cytosolic protein 2 | 0.017 | ||
Hmbox1 | homeobox containing 1 | 0.017 | ||
Hmgxb4 | HMG box domain containing 4 | 0.017 | ||
Saal1 | serum amyloid A-like 1 | 0.016 | ||
Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.016 | ||
Zw10 | ZW10 homolog (Drosophila), centromere/kinetochore protein | 0.016 | ||
Hjurp | Holliday junction recognition protein | 0.016 | ||
Nup188 | nucleoporin 188 | 0.016 | ||
Tcf3 | transcription factor 3 | 0.015 | ||
Usp48 | ubiquitin specific peptidase 48 | 0.015 | ||
Odf2 | outer dense fiber of sperm tails 2 | 0.015 | ||
Snhg5 | small nucleolar RNA host gene 5 | 0.015 | ||
Cdk5rap2 | CDK5 regulatory subunit associated protein 2 | 0.015 | ||
Terf2 | telomeric repeat binding factor 2 | 0.015 | ||
AW146020 | expressed sequence AW146020 | 0.014 | ||
Asxl1 | additional sex combs like 1 (Drosophila) | 0.014 | ||
Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.014 | ||
Ankrd26 | ankyrin repeat domain 26 | 0.014 | ||
Hltf | helicase-like transcription factor | 0.014 | ||
Rnf219 | ring finger protein 219 | 0.014 | ||
Sp1 | trans-acting transcription factor 1 | 0.014 | ||
Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.014 | ||
Brd8 | bromodomain containing 8 | 0.014 | ||
Clk2 | CDC-like kinase 2 | 0.013 | ||
Men1 | multiple endocrine neoplasia 1 | 0.013 | ||
1500010J02Rik | RIKEN cDNA 1500010J02 gene | 0.013 | ||
Rps6kb1 | ribosomal protein S6 kinase, polypeptide 1 | 0.013 | ||
Pinx1 | PIN2/TERF1 interacting, telomerase inhibitor 1 | 0.013 | ||
Setdb1 | SET domain, bifurcated 1 | 0.013 | ||
Pot1b | protection of telomeres 1B | 0.013 | ||
Dclre1a | DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae) | 0.013 | ||
Med1 | mediator complex subunit 1 | 0.013 | ||
Rtel1 | regulator of telomere elongation helicase 1 | 0.013 | ||
Arid4a | AT rich interactive domain 4A (RBP1-like) | 0.012 | ||
Spice1 | spindle and centriole associated protein 1 | 0.012 | ||
Narg2 | NMDA receptor-regulated gene 2 | 0.012 | ||
C2cd3 | C2 calcium-dependent domain containing 3 | 0.012 | ||
Ncapd3 | non-SMC condensin II complex, subunit D3 | 0.012 | ||
Chek2 | CHK2 checkpoint homolog (S. pombe) | 0.012 | ||
Tubgcp4 | tubulin, gamma complex associated protein 4 | 0.012 | ||
Alms1 | Alstrom syndrome 1 homolog (human) | 0.012 | ||
Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.012 | ||
Xpo7 | exportin 7 | 0.012 | ||
Mtbp | Mdm2, transformed 3T3 cell double minute p53 binding protein | 0.012 | ||
Daxx | Fas death domain-associated protein | 0.011 | ||
6030458C11Rik | RIKEN cDNA 6030458C11 gene | 0.011 | ||
Tia1 | cytotoxic granule-associated RNA binding protein 1 | 0.011 | ||
Tinf2 | Terf1 (TRF1)-interacting nuclear factor 2 | 0.011 | ||
Bod1l | biorientation of chromosomes in cell division 1-like | 0.011 | ||
Zmynd8 | zinc finger, MYND-type containing 8 | 0.011 | ||
Prmt3 | protein arginine N-methyltransferase 3 | 0.011 | ||
Ift140 | intraflagellar transport 140 homolog (Chlamydomonas) | 0.011 | ||
Wdr67 | WD repeat domain 67 | 0.011 | ||
Helb | helicase (DNA) B | 0.011 | ||
Senp1 | SUMO1/sentrin specific peptidase 1 | 0.010 | ||
Phtf1 | putative homeodomain transcription factor 1 | 0.010 | ||
Ikzf3 | IKAROS family zinc finger 3 | 0.010 | ||
Tdp1 | tyrosyl-DNA phosphodiesterase 1 | 0.010 | ||
Dcps | decapping enzyme, scavenger | 0.010 | ||
Casp3 | caspase 3 | 0.010 | ||
2700049A03Rik | RIKEN cDNA 2700049A03 gene | 0.010 |