IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

nuclear dna replication

GO:0033260

The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nuclear dna replication"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "nuclear dna replication" (in gray)

Name	Description	Probability	Func Analog Organism
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.998	Yeast
Mapk14	mitogen-activated protein kinase 14	0.992	Yeast
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.951	Yeast
Cdt1	chromatin licensing and DNA replication factor 1	0.940
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.934	Yeast
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.874	Yeast
Ccna2	cyclin A2	0.643
Timeless	timeless homolog (Drosophila)	0.631
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.549	Yeast
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.513
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.478
Lig1	ligase I, DNA, ATP-dependent	0.429
Ncaph	non-SMC condensin I complex, subunit H	0.421
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.410
Ccne1	cyclin E1	0.388
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.351
Rpgrip1l	Rpgrip1-like	0.350
Atf2	activating transcription factor 2	0.308
Rfc2	replication factor C (activator 1) 2	0.304
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.286
Prc1	protein regulator of cytokinesis 1	0.252
Cdca5	cell division cycle associated 5	0.229
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.222
Orc6	origin recognition complex, subunit 6	0.216
Zfp930	zinc finger protein 930	0.212
Smc1a	structural maintenance of chromosomes 1A	0.199
Tcf19	transcription factor 19	0.197
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.194
Trp53	transformation related protein 53	0.190
Mcm6	minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	0.190	Yeast
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.185	Yeast
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.181
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.166
Orc1	origin recognition complex, subunit 1	0.162
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.160
Rrm2	ribonucleotide reductase M2	0.151
Rrm1	ribonucleotide reductase M1	0.149
Pole	polymerase (DNA directed), epsilon	0.141
Kif22	kinesin family member 22	0.140
Ccnb2	cyclin B2	0.124
Cdca8	cell division cycle associated 8	0.123
Rabep1	rabaptin, RAB GTPase binding effector protein 1	0.119
Top2a	topoisomerase (DNA) II alpha	0.113
Mapk11	mitogen-activated protein kinase 11	0.108	Yeast
Mapk8	mitogen-activated protein kinase 8	0.107	Yeast
Aurkb	aurora kinase B	0.102
Rfc5	replication factor C (activator 1) 5	0.098
Lrrk2	leucine-rich repeat kinase 2	0.096
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.092
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.087
Rad51ap1	RAD51 associated protein 1	0.086
Cdca7	cell division cycle associated 7	0.079
Mecp2	methyl CpG binding protein 2	0.076
Cdc7	cell division cycle 7 (S. cerevisiae)	0.075	Human
Plk4	polo-like kinase 4 (Drosophila)	0.073
Tk1	thymidine kinase 1	0.073
Plk1	polo-like kinase 1 (Drosophila)	0.071
Cdca4	cell division cycle associated 4	0.071
Brca2	breast cancer 2	0.071
Fen1	flap structure specific endonuclease 1	0.069
Prim1	DNA primase, p49 subunit	0.067
Ung	uracil DNA glycosylase	0.064
Haus3	HAUS augmin-like complex, subunit 3	0.063
Dnajc9	DnaJ (Hsp40) homolog, subfamily C, member 9	0.060
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.057
Rad51	RAD51 homolog (S. cerevisiae)	0.056
Ccnf	cyclin F	0.056
Haus5	HAUS augmin-like complex, subunit 5	0.055
Incenp	inner centromere protein	0.055
Cdca7l	cell division cycle associated 7 like	0.055
Mapk9	mitogen-activated protein kinase 9	0.053	Yeast
Mki67	antigen identified by monoclonal antibody Ki 67	0.050
Cks1b	CDC28 protein kinase 1b	0.048
Racgap1	Rac GTPase-activating protein 1	0.048
Ncapd3	non-SMC condensin II complex, subunit D3	0.048
Aurka	aurora kinase A	0.047
Mapkapk2	MAP kinase-activated protein kinase 2	0.047
Gtse1	G two S phase expressed protein 1	0.045
Nup107	nucleoporin 107	0.045
Iqcb1	IQ calmodulin-binding motif containing 1	0.044
Ints7	integrator complex subunit 7	0.043
Hells	helicase, lymphoid specific	0.042
Smc3	structural maintenace of chromosomes 3	0.042
Mybl2	myeloblastosis oncogene-like 2	0.042
Mlh1	mutL homolog 1 (E. coli)	0.041
Orc2	origin recognition complex, subunit 2	0.041	Yeast
Hist1h1a	histone cluster 1, H1a	0.040
E2f1	E2F transcription factor 1	0.040
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.039
Ccnb1	cyclin B1	0.039
Mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.039
Blzf1	basic leucine zipper nuclear factor 1	0.037
Kif11	kinesin family member 11	0.037
Pou5f1	POU domain, class 5, transcription factor 1	0.036
Ccdc99	coiled-coil domain containing 99	0.034
Myef2	myelin basic protein expression factor 2, repressor	0.034
Klc1	kinesin light chain 1	0.034
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.033
Brca1	breast cancer 1	0.033
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.032
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.032
Ggps1	geranylgeranyl diphosphate synthase 1	0.031
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.031
H1	histocompatibility 1	0.030
Spag9	sperm associated antigen 9	0.030
Mms22l	MMS22-like, DNA repair protein	0.030
Pola1	polymerase (DNA directed), alpha 1	0.030
Prim2	DNA primase, p58 subunit	0.029
Mtf2	metal response element binding transcription factor 2	0.029
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.029
Arhgap8	Rho GTPase activating protein 8	0.029
Msh2	mutS homolog 2 (E. coli)	0.028
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.028
Stmn1	stathmin 1	0.028
Ncapd2	non-SMC condensin I complex, subunit D2	0.027
Birc5	baculoviral IAP repeat-containing 5	0.027
Klf5	Kruppel-like factor 5	0.026
Llgl2	lethal giant larvae homolog 2 (Drosophila)	0.026
Tipin	timeless interacting protein	0.026
Dnm1l	dynamin 1-like	0.025
Haus4	HAUS augmin-like complex, subunit 4	0.025
Ccne2	cyclin E2	0.025
Dhfr	dihydrofolate reductase	0.025
Rcc1	regulator of chromosome condensation 1	0.024
Hdac1	histone deacetylase 1	0.024
Dna2	DNA replication helicase 2 homolog (yeast)	0.024
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.024
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.023
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.023
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.023
Eed	embryonic ectoderm development	0.023
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.023
2410089E03Rik	RIKEN cDNA 2410089E03 gene	0.023
Kif23	kinesin family member 23	0.022
Zfp146	zinc finger protein 146	0.022
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.021
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.021
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.021
Gmnn	geminin	0.021
Dck	deoxycytidine kinase	0.021
Ckap2	cytoskeleton associated protein 2	0.021
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.020
Wwox	WW domain-containing oxidoreductase	0.020
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.020
Pbk	PDZ binding kinase	0.020
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.020
Rbl1	retinoblastoma-like 1 (p107)	0.020
Rps6	ribosomal protein S6	0.019
Mtmr1	myotubularin related protein 1	0.019
Lmna	lamin A	0.019
D030056L22Rik	RIKEN cDNA D030056L22 gene	0.019
Pola2	polymerase (DNA directed), alpha 2	0.019
Zbtb7b	zinc finger and BTB domain containing 7B	0.018
Anln	anillin, actin binding protein	0.018
Slbp	stem-loop binding protein	0.018	Human
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.018
Lmnb1	lamin B1	0.018
Zmym1	zinc finger, MYM domain containing 1	0.018
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.018
Rtn2	reticulon 2 (Z-band associated protein)	0.017
Orc3	origin recognition complex, subunit 3	0.017
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.017
Scg3	secretogranin III	0.017
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.017
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.017
Smc2	structural maintenance of chromosomes 2	0.017
Blm	Bloom syndrome, RecQ helicase-like	0.017
Pmf1	polyamine-modulated factor 1	0.016
Gsta4	glutathione S-transferase, alpha 4	0.016
Zwilch	Zwilch, kinetochore associated, homolog (Drosophila)	0.016
Chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.016
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.016
Zfp955b	zinc finger protein 955B	0.016
Klc2	kinesin light chain 2	0.016
Krtcap3	keratinocyte associated protein 3	0.016
Skp2	S-phase kinase-associated protein 2 (p45)	0.016
Snap25	synaptosomal-associated protein 25	0.016
Mphosph9	M-phase phosphoprotein 9	0.015
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.015
Ate1	arginyltransferase 1	0.015
Hist1h3g	histone cluster 1, H3g	0.015
Vcl	vinculin	0.015
Irf6	interferon regulatory factor 6	0.015
Pcna	proliferating cell nuclear antigen	0.015
Mbd4	methyl-CpG binding domain protein 4	0.015
Mthfd1l	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.015
Kif20a	kinesin family member 20A	0.015
Ldoc1l	leucine zipper, down-regulated in cancer 1-like	0.015
Prkce	protein kinase C, epsilon	0.015
Rfwd3	ring finger and WD repeat domain 3	0.015
Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.014
Stmn3	stathmin-like 3	0.014
Trip13	thyroid hormone receptor interactor 13	0.014
Tacc3	transforming, acidic coiled-coil containing protein 3	0.014
Rps3a	ribosomal protein S3A	0.014
Raf1	v-raf-leukemia viral oncogene 1	0.014
Tbc1d4	TBC1 domain family, member 4	0.014
Scoc	short coiled-coil protein	0.014
Pask	PAS domain containing serine/threonine kinase	0.014
Cdcp1	CUB domain containing protein 1	0.014
Kif2a	kinesin family member 2A	0.014
4933439F18Rik	RIKEN cDNA 4933439F18 gene	0.014
Hcfc1	host cell factor C1	0.014
Nvl	nuclear VCP-like	0.014
Rpusd1	RNA pseudouridylate synthase domain containing 1	0.014
Zfp639	zinc finger protein 639	0.014
Cstf2	cleavage stimulation factor, 3' pre-RNA subunit 2	0.013
Ankrd26	ankyrin repeat domain 26	0.013
2900011O08Rik	RIKEN cDNA 2900011O08 gene	0.013
Lipe	lipase, hormone sensitive	0.013
Mapkbp1	mitogen-activated protein kinase binding protein 1	0.013
Zfml	zinc finger, matrin-like	0.013
Rps16	ribosomal protein S16	0.013
Fancg	Fanconi anemia, complementation group G	0.013
Ncapg2	non-SMC condensin II complex, subunit G2	0.013
Dtl	denticleless homolog (Drosophila)	0.013
Mta1	metastasis associated 1	0.013
Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like	0.013
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.013
Psmd11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.013
Txlnb	taxilin beta	0.013
Haus6	HAUS augmin-like complex, subunit 6	0.013
Lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.013
Hspb3	heat shock protein 3	0.013
Phospho2	phosphatase, orphan 2	0.013
Rpl3l	ribosomal protein L3-like	0.013
Eri2	exoribonuclease 2	0.013
Pkp3	plakophilin 3	0.013
Smtnl1	smoothelin-like 1	0.013
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.012
Capn5	calpain 5	0.012
Trp73	transformation related protein 73	0.012
Ttn	titin	0.012
Jun	Jun oncogene	0.012
Gmfb	glia maturation factor, beta	0.012
Zfp35	zinc finger protein 35	0.012
Tjp3	tight junction protein 3	0.012
Trim54	tripartite motif-containing 54	0.012
Kpna1	karyopherin (importin) alpha 1	0.012
Vill	villin-like	0.012
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.012
Serpini1	serine (or cysteine) peptidase inhibitor, clade I, member 1	0.012
Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	0.012
Nup93	nucleoporin 93	0.012
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.012
Homer1	homer homolog 1 (Drosophila)	0.012
1110034B05Rik	RIKEN cDNA 1110034B05 gene	0.012
Tgif2	TGFB-induced factor homeobox 2	0.012
Zfp142	zinc finger protein 142	0.012
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.012
Ube2c	ubiquitin-conjugating enzyme E2C	0.012
Syce2	synaptonemal complex central element protein 2	0.012
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
Dazap1	DAZ associated protein 1	0.012
Spint1	serine protease inhibitor, Kunitz type 1	0.012
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.012
Naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)	0.012
E2f4	E2F transcription factor 4	0.011
Stxbp1	syntaxin binding protein 1	0.011
E130303B06Rik	RIKEN cDNA E130303B06 gene	0.011
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.011
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.011
Tonsl	tonsoku-like, DNA repair protein	0.011
Zscan4b	zinc finger and SCAN domain containing 4B	0.011
Gripap1	GRIP1 associated protein 1	0.011
Usf2	upstream transcription factor 2	0.011
Ube3a	ubiquitin protein ligase E3A	0.011
Rad1	RAD1 homolog (S. pombe)	0.011
Rpa2	replication protein A2	0.011
Zfp445	zinc finger protein 445	0.011
Cenpa	centromere protein A	0.011
Recql4	RecQ protein-like 4	0.011
E2f8	E2F transcription factor 8	0.011
Cdk2	cyclin-dependent kinase 2	0.011	Yeast
Ttf2	transcription termination factor, RNA polymerase II	0.011
Scn4b	sodium channel, type IV, beta	0.011
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.011
Fyttd1	forty-two-three domain containing 1	0.011
Rpap2	RNA polymerase II associated protein 2	0.011
Scmh1	sex comb on midleg homolog 1	0.011
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.011
Ncor2	nuclear receptor co-repressor 2	0.011
Rybp	RING1 and YY1 binding protein	0.011
Smc6	structural maintenance of chromosomes 6	0.011
Ccnd1	cyclin D1	0.010
Ak1	adenylate kinase 1	0.010
Rps4x	ribosomal protein S4, X-linked	0.010
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.010
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.010
Phgdh	3-phosphoglycerate dehydrogenase	0.010
H2afx	H2A histone family, member X	0.010
Arf2	ADP-ribosylation factor 2	0.010
Asb11	ankyrin repeat and SOCS box-containing 11	0.010
4930430F08Rik	RIKEN cDNA 4930430F08 gene	0.010
Lrrc2	leucine rich repeat containing 2	0.010
Iqgap3	IQ motif containing GTPase activating protein 3	0.010
Dsg4	desmoglein 4	0.010
Ache	acetylcholinesterase	0.010
Gsk3a	glycogen synthase kinase 3 alpha	0.010
Ccdc132	coiled-coil domain containing 132	0.010
Arhgdig	Rho GDP dissociation inhibitor (GDI) gamma	0.010
Ckap5	cytoskeleton associated protein 5	0.010
Msh6	mutS homolog 6 (E. coli)	0.010
Ppp1r13l	protein phosphatase 1, regulatory (inhibitor) subunit 13 like	0.010
Lipt1	lipoyltransferase 1	0.010