IMP
Process View
mitotic sister chromatid cohesion
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitotic sister chromatid cohesion"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Smc1a | structural maintenance of chromosomes 1A | 0.998 | Yeast | |
| Pten | phosphatase and tensin homolog | 0.924 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.889 | ||
| Brca1 | breast cancer 1 | 0.872 | ||
| Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.862 | ||
| Pds5a | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) | 0.749 | Human Worm | |
| Smc3 | structural maintenace of chromosomes 3 | 0.713 | Yeast Zebrafish | |
| Rb1 | retinoblastoma 1 | 0.698 | Human | |
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.590 | ||
| Brca2 | breast cancer 2 | 0.545 | ||
| Cenpf | centromere protein F | 0.524 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.493 | ||
| Zfp871 | zinc finger protein 871 | 0.489 | ||
| Pold1 | polymerase (DNA directed), delta 1, catalytic subunit | 0.487 | ||
| Sgol1 | shugoshin-like 1 (S. pombe) | 0.486 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.479 | ||
| Stag2 | stromal antigen 2 | 0.440 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.402 | ||
| Rbl2 | retinoblastoma-like 2 | 0.377 | Fly | |
| E2f1 | E2F transcription factor 1 | 0.325 | ||
| Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.313 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.313 | ||
| Mms22l | MMS22-like, DNA repair protein | 0.308 | ||
| Trp53 | transformation related protein 53 | 0.287 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.278 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.272 | ||
| Timeless | timeless homolog (Drosophila) | 0.266 | Worm | |
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.244 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.240 | ||
| Dtl | denticleless homolog (Drosophila) | 0.239 | ||
| Tpx2 | TPX2, microtubule-associated protein homolog (Xenopus laevis) | 0.237 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.216 | ||
| Clspn | claspin homolog (Xenopus laevis) | 0.204 | ||
| Ccnf | cyclin F | 0.203 | ||
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.190 | ||
| Aspm | asp (abnormal spindle)-like, microcephaly associated (Drosophila) | 0.185 | ||
| Stag1 | stromal antigen 1 | 0.174 | ||
| Ttk | Ttk protein kinase | 0.170 | ||
| Ndc80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.170 | ||
| Kif2c | kinesin family member 2C | 0.169 | ||
| Kif22 | kinesin family member 22 | 0.163 | ||
| Ncaph | non-SMC condensin I complex, subunit H | 0.146 | ||
| Aurkb | aurora kinase B | 0.146 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.139 | ||
| Lig1 | ligase I, DNA, ATP-dependent | 0.139 | ||
| Mycbp2 | MYC binding protein 2 | 0.138 | ||
| Exo1 | exonuclease 1 | 0.132 | ||
| Kif11 | kinesin family member 11 | 0.131 | ||
| Atf2 | activating transcription factor 2 | 0.129 | ||
| Cenpn | centromere protein N | 0.128 | ||
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.127 | ||
| Kif4 | kinesin family member 4 | 0.123 | ||
| Cdt1 | chromatin licensing and DNA replication factor 1 | 0.110 | ||
| Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.109 | ||
| Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.108 | ||
| Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.104 | ||
| Ercc6l | excision repair cross-complementing rodent repair deficiency complementation group 6 - like | 0.102 | ||
| Uhrf1 | ubiquitin-like, containing PHD and RING finger domains, 1 | 0.100 | ||
| Melk | maternal embryonic leucine zipper kinase | 0.099 | ||
| Pds5b | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.098 | Human Worm | |
| Cdca2 | cell division cycle associated 2 | 0.095 | ||
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.095 | ||
| Scaf11 | SR-related CTD-associated factor 11 | 0.091 | ||
| Ncoa6 | nuclear receptor coactivator 6 | 0.090 | ||
| Kif20a | kinesin family member 20A | 0.090 | ||
| Pole | polymerase (DNA directed), epsilon | 0.088 | Yeast | |
| Cenpe | centromere protein E | 0.086 | ||
| Apc | adenomatosis polyposis coli | 0.084 | ||
| Ckap2 | cytoskeleton associated protein 2 | 0.080 | ||
| Mcm5 | minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 0.079 | ||
| Eme1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.079 | ||
| Rad51 | RAD51 homolog (S. cerevisiae) | 0.079 | ||
| Rsf1 | remodeling and spacing factor 1 | 0.078 | ||
| Mis18bp1 | MIS18 binding protein 1 | 0.077 | ||
| Ncapg | non-SMC condensin I complex, subunit G | 0.075 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.075 | ||
| Dlg1 | discs, large homolog 1 (Drosophila) | 0.074 | ||
| Mcm2 | minichromosome maintenance deficient 2 mitotin (S. cerevisiae) | 0.070 | ||
| Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 | 0.068 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.066 | ||
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.065 | ||
| Racgap1 | Rac GTPase-activating protein 1 | 0.065 | ||
| Crebbp | CREB binding protein | 0.065 | ||
| Txndc16 | thioredoxin domain containing 16 | 0.064 | ||
| Blm | Bloom syndrome, RecQ helicase-like | 0.064 | ||
| Usp9x | ubiquitin specific peptidase 9, X chromosome | 0.063 | ||
| Incenp | inner centromere protein | 0.063 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.063 | ||
| Ccna2 | cyclin A2 | 0.061 | ||
| E2f8 | E2F transcription factor 8 | 0.058 | ||
| Cnot6l | CCR4-NOT transcription complex, subunit 6-like | 0.057 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.057 | ||
| Bod1l | biorientation of chromosomes in cell division 1-like | 0.055 | ||
| Kif23 | kinesin family member 23 | 0.055 | ||
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.054 | ||
| Ncor1 | nuclear receptor co-repressor 1 | 0.054 | ||
| Kntc1 | kinetochore associated 1 | 0.054 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.051 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.049 | ||
| Stil | Scl/Tal1 interrupting locus | 0.049 | ||
| Zranb2 | zinc finger, RAN-binding domain containing 2 | 0.047 | ||
| Ptch1 | patched homolog 1 | 0.046 | ||
| Rmnd5a | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.045 | ||
| Cep55 | centrosomal protein 55 | 0.045 | ||
| Cbx5 | chromobox homolog 5 (Drosophila HP1a) | 0.044 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.043 | ||
| Rad54l | RAD54 like (S. cerevisiae) | 0.041 | ||
| Foxo3 | forkhead box O3 | 0.041 | ||
| Thoc2 | THO complex 2 | 0.040 | ||
| Fbxo5 | F-box protein 5 | 0.039 | ||
| Vezf1 | vascular endothelial zinc finger 1 | 0.039 | ||
| Chtf18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) | 0.039 | ||
| Lrr1 | leucine rich repeat protein 1 | 0.038 | ||
| Kit | kit oncogene | 0.036 | ||
| Xpo1 | exportin 1, CRM1 homolog (yeast) | 0.036 | ||
| Lmnb1 | lamin B1 | 0.034 | ||
| Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.034 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.034 | ||
| Ash1l | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.033 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.033 | ||
| Pcmtd2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.032 | ||
| Brd8 | bromodomain containing 8 | 0.032 | ||
| Gtse1 | G two S phase expressed protein 1 | 0.032 | ||
| Arid2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.032 | ||
| Ncapd2 | non-SMC condensin I complex, subunit D2 | 0.031 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.031 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.031 | ||
| Ep300 | E1A binding protein p300 | 0.031 | ||
| Kitl | kit ligand | 0.030 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.030 | ||
| Ckap2l | cytoskeleton associated protein 2-like | 0.030 | ||
| Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.029 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.028 | ||
| Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.028 | ||
| Tk1 | thymidine kinase 1 | 0.028 | ||
| Ccdc99 | coiled-coil domain containing 99 | 0.027 | ||
| Zfp280d | zinc finger protein 280D | 0.027 | ||
| Nfatc3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.027 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.027 | ||
| Ctcf | CCCTC-binding factor | 0.027 | ||
| Aurka | aurora kinase A | 0.027 | ||
| Cenpm | centromere protein M | 0.026 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.026 | Fly | |
| Trip13 | thyroid hormone receptor interactor 13 | 0.026 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.026 | ||
| Top2b | topoisomerase (DNA) II beta | 0.025 | ||
| Spag5 | sperm associated antigen 5 | 0.025 | ||
| Dna2 | DNA replication helicase 2 homolog (yeast) | 0.024 | ||
| Mbtd1 | mbt domain containing 1 | 0.023 | ||
| Pdpk1 | 3-phosphoinositide dependent protein kinase 1 | 0.023 | ||
| Spnb2 | spectrin beta 2 | 0.023 | ||
| Cdca7l | cell division cycle associated 7 like | 0.022 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.022 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.022 | ||
| Cenpi | centromere protein I | 0.022 | ||
| Diap3 | diaphanous homolog 3 (Drosophila) | 0.022 | ||
| Bptf | bromodomain PHD finger transcription factor | 0.021 | ||
| Nfyb | nuclear transcription factor-Y beta | 0.021 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.021 | ||
| Prpf4b | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 0.021 | ||
| Cenpk | centromere protein K | 0.021 | ||
| D2Ertd750e | DNA segment, Chr 2, ERATO Doi 750, expressed | 0.021 | ||
| Cdca8 | cell division cycle associated 8 | 0.020 | ||
| Ccnb1 | cyclin B1 | 0.020 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.020 | ||
| Ndufaf4 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4 | 0.020 | ||
| Mcm10 | minichromosome maintenance deficient 10 (S. cerevisiae) | 0.019 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.019 | ||
| Kdm6a | 4lysine (K)-specific demethylase 6A | 0.019 | ||
| Zcchc11 | zinc finger, CCHC domain containing 11 | 0.019 | ||
| Psen1 | presenilin 1 | 0.019 | ||
| Tcf19 | transcription factor 19 | 0.019 | ||
| Chek2 | CHK2 checkpoint homolog (S. pombe) | 0.018 | ||
| Orc1 | origin recognition complex, subunit 1 | 0.018 | ||
| Macf1 | microtubule-actin crosslinking factor 1 | 0.018 | ||
| Pum1 | pumilio 1 (Drosophila) | 0.018 | ||
| Mastl | microtubule associated serine/threonine kinase-like | 0.018 | ||
| 2610101N10Rik | RIKEN cDNA 2610101N10 gene | 0.017 | ||
| Gins1 | GINS complex subunit 1 (Psf1 homolog) | 0.017 | ||
| Cdkn2d | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 0.017 | ||
| Zmym5 | zinc finger, MYM-type 5 | 0.017 | ||
| Espl1 | extra spindle poles-like 1 (S. cerevisiae) | 0.017 | ||
| Ncapd3 | non-SMC condensin II complex, subunit D3 | 0.016 | ||
| Ncoa1 | nuclear receptor coactivator 1 | 0.016 | ||
| Sltm | SAFB-like, transcription modulator | 0.016 | ||
| Krit1 | KRIT1, ankyrin repeat containing | 0.016 | ||
| Trip12 | thyroid hormone receptor interactor 12 | 0.016 | ||
| Akap9 | A kinase (PRKA) anchor protein (yotiao) 9 | 0.016 | ||
| Rif1 | Rap1 interacting factor 1 homolog (yeast) | 0.016 | ||
| Senp6 | SUMO/sentrin specific peptidase 6 | 0.015 | ||
| Rfx7 | regulatory factor X, 7 | 0.015 | ||
| Rfc5 | replication factor C (activator 1) 5 | 0.015 | ||
| Pias1 | protein inhibitor of activated STAT 1 | 0.015 | ||
| Cenpa | centromere protein A | 0.015 | ||
| E2f7 | E2F transcription factor 7 | 0.015 | ||
| Ruvbl2 | RuvB-like protein 2 | 0.015 | ||
| Kif20b | kinesin family member 20B | 0.015 | ||
| Pkdcc | protein kinase domain containing, cytoplasmic | 0.015 | ||
| Tmpo | thymopoietin | 0.015 | ||
| Ylpm1 | YLP motif containing 1 | 0.014 | ||
| Ung | uracil DNA glycosylase | 0.014 | ||
| Mns1 | meiosis-specific nuclear structural protein 1 | 0.014 | ||
| Iqgap3 | IQ motif containing GTPase activating protein 3 | 0.014 | ||
| Eri2 | exoribonuclease 2 | 0.014 | ||
| Wrn | Werner syndrome homolog (human) | 0.014 | ||
| Mysm1 | myb-like, SWIRM and MPN domains 1 | 0.014 | ||
| Smc2 | structural maintenance of chromosomes 2 | 0.014 | ||
| Casp3 | caspase 3 | 0.014 | ||
| Atad2 | ATPase family, AAA domain containing 2 | 0.014 | ||
| Birc5 | baculoviral IAP repeat-containing 5 | 0.014 | ||
| Nipbl | Nipped-B homolog (Drosophila) | 0.014 | Human | |
| Wapal | wings apart-like homolog (Drosophila) | 0.014 | ||
| AW549877 | expressed sequence AW549877 | 0.014 | ||
| Anp32e | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.014 | ||
| Rad51c | RAD51 homolog c (S. cerevisiae) | 0.014 | ||
| Wnk1 | WNK lysine deficient protein kinase 1 | 0.013 | ||
| Pum2 | pumilio 2 (Drosophila) | 0.013 | ||
| Usp33 | ubiquitin specific peptidase 33 | 0.013 | ||
| Hook3 | hook homolog 3 (Drosophila) | 0.013 | ||
| Ola1 | Obg-like ATPase 1 | 0.013 | ||
| Hnrnpul2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.013 | ||
| A930001N09Rik | RIKEN cDNA A930001N09 gene | 0.013 | ||
| Pold2 | polymerase (DNA directed), delta 2, regulatory subunit | 0.013 | ||
| Sesn1 | sestrin 1 | 0.013 | ||
| Arid4a | AT rich interactive domain 4A (RBP1-like) | 0.013 | ||
| Smc6 | structural maintenance of chromosomes 6 | 0.013 | ||
| Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) | 0.013 | ||
| Phip | pleckstrin homology domain interacting protein | 0.013 | ||
| Wdr26 | WD repeat domain 26 | 0.013 | ||
| Tacc3 | transforming, acidic coiled-coil containing protein 3 | 0.012 | ||
| Hells | helicase, lymphoid specific | 0.012 | ||
| 2810417H13Rik | RIKEN cDNA 2810417H13 gene | 0.012 | ||
| Jarid2 | jumonji, AT rich interactive domain 2 | 0.012 | ||
| Rad21 | RAD21 homolog (S. pombe) | 0.012 | ||
| G2e3 | G2/M-phase specific E3 ubiquitin ligase | 0.012 | ||
| Cenpt | centromere protein T | 0.012 | ||
| Atad1 | ATPase family, AAA domain containing 1 | 0.012 | ||
| Spc24 | SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.012 | ||
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.012 | ||
| Zfp292 | zinc finger protein 292 | 0.012 | ||
| Cenph | centromere protein H | 0.012 | ||
| Dram2 | VDNA-damage regulated autophagy modulator 2 | 0.012 | ||
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.012 | ||
| Ulk2 | Unc-51 like kinase 2 (C. elegans) | 0.012 | ||
| Trim33 | tripartite motif-containing 33 | 0.012 | ||
| Gen1 | Gen homolog 1, endonuclease (Drosophila) | 0.011 | ||
| Taf6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor | 0.011 | ||
| 2700049A03Rik | RIKEN cDNA 2700049A03 gene | 0.011 | ||
| Sp1 | trans-acting transcription factor 1 | 0.011 | ||
| Fanca | Fanconi anemia, complementation group A | 0.011 | ||
| Zmym2 | zinc finger, MYM-type 2 | 0.011 | ||
| Myo6 | myosin VI | 0.011 | ||
| 4921513D23Rik | RIKEN cDNA 4921513D23 gene | 0.011 | ||
| Suv420h1 | suppressor of variegation 4-20 homolog 1 (Drosophila) | 0.011 | ||
| Ckap5 | cytoskeleton associated protein 5 | 0.011 | ||
| Cdc25a | cell division cycle 25 homolog A (S. pombe) | 0.011 | ||
| Nktr | natural killer tumor recognition sequence | 0.011 | ||
| Prkd3 | protein kinase D3 | 0.011 | ||
| Hp1bp3 | heterochromatin protein 1, binding protein 3 | 0.011 | ||
| Braf | Braf transforming gene | 0.011 | ||
| F630043A04Rik | RIKEN cDNA F630043A04 gene | 0.011 | ||
| Ccne1 | cyclin E1 | 0.010 | ||
| Lcorl | ligand dependent nuclear receptor corepressor-like | 0.010 | ||
| Mphosph9 | M-phase phosphoprotein 9 | 0.010 | ||
| Rfc1 | replication factor C (activator 1) 1 | 0.010 | ||
| Rapgef6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.010 | ||
| Foxm1 | forkhead box M1 | 0.010 | ||
| Igh | immunoglobulin heavy chain complex | 0.010 | ||
| Tnks2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.010 |