IMP: Integrative Multi-species Prediction

Mus musculus

65 genes annotated in mouse

negative regulation of mapk cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mapk cascade"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of mapk cascade" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	0.988	Mouse
Apc	adenomatosis polyposis coli	0.865
Grb2	growth factor receptor bound protein 2	0.853
Mapk1	mitogen-activated protein kinase 1	0.825	Yeast
Per2	period homolog 2 (Drosophila)	0.813
Mdm2	transformed mouse 3T3 cell double minute 2	0.804
Pten	phosphatase and tensin homolog	0.804
Inpp5d	inositol polyphosphate-5-phosphatase D	0.775
Ctnnb1	catenin (cadherin associated protein), beta 1	0.717
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.705	Mouse
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.664
Lyz2	lysozyme 2	0.621
Traf6	TNF receptor-associated factor 6	0.609
Ptprc	protein tyrosine phosphatase, receptor type, C	0.592
Dok1	docking protein 1	0.592
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.559
Axin1	axin 1	0.526
Atf2	activating transcription factor 2	0.520
Cd44	CD44 antigen	0.508
Cav1	caveolin 1, caveolae protein	0.467
Lcp1	lymphocyte cytosolic protein 1	0.463
Fyn	Fyn proto-oncogene	0.461	Mouse
Cbl	Casitas B-lineage lymphoma	0.439
Tsc1	tuberous sclerosis 1	0.420
Prkce	protein kinase C, epsilon	0.396	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.384
Dmd	dystrophin, muscular dystrophy	0.381
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.345
Nos1	nitric oxide synthase 1, neuronal	0.344
Csf1r	colony stimulating factor 1 receptor	0.322
Fos	FBJ osteosarcoma oncogene	0.309
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.303
Mapk14	mitogen-activated protein kinase 14	0.303
Shc1	src homology 2 domain-containing transforming protein C1	0.297
Mapk8	mitogen-activated protein kinase 8	0.297	Fly
Cyld	cylindromatosis (turban tumor syndrome)	0.292
Tnf	tumor necrosis factor	0.291
Vasp	vasodilator-stimulated phosphoprotein	0.290	Mouse
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.287
Adam17	a disintegrin and metallopeptidase domain 17	0.262
Grb10	growth factor receptor bound protein 10	0.258
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.255
Rb1	retinoblastoma 1	0.252
C1qc	complement component 1, q subcomponent, C chain	0.251	Mouse
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.248
Cd80	CD80 antigen	0.247
Ly86	lymphocyte antigen 86	0.236
Ccl4	chemokine (C-C motif) ligand 4	0.236
Ncoa3	nuclear receptor coactivator 3	0.229
Csf1	colony stimulating factor 1 (macrophage)	0.222
Il1b	interleukin 1 beta	0.215
Prkcb	protein kinase C, beta	0.207	Mouse
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.205
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.194
Spnb2	spectrin beta 2	0.190
Insr	insulin receptor	0.190	Mouse
Mdm4	transformed mouse 3T3 cell double minute 4	0.188
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.187
Klf7	Kruppel-like factor 7 (ubiquitous)	0.186
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.185
Smad4	MAD homolog 4 (Drosophila)	0.185
Col1a1	collagen, type I, alpha 1	0.181
Btk	Bruton agammaglobulinemia tyrosine kinase	0.181	Mouse
Fbxw7	F-box and WD-40 domain protein 7	0.179
Prkcc	protein kinase C, gamma	0.176
Skil	SKI-like	0.175
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.170
Cdh5	cadherin 5	0.165
Tgfb1	transforming growth factor, beta 1	0.161
Nsf	N-ethylmaleimide sensitive fusion protein	0.158
Grm1	glutamate receptor, metabotropic 1	0.158
Usp8	ubiquitin specific peptidase 8	0.157
Nf2	neurofibromatosis 2	0.156
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.154
Ccnd1	cyclin D1	0.153
Csk	c-src tyrosine kinase	0.153	Rat
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.153
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.152
Ptk2	PTK2 protein tyrosine kinase 2	0.151	Fly
Ezh1	enhancer of zeste homolog 1 (Drosophila)	0.144
Jun	Jun oncogene	0.144
Cotl1	coactosin-like 1 (Dictyostelium)	0.142
Mmp9	matrix metallopeptidase 9	0.141
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.141
Sh3kbp1	SH3-domain kinase binding protein 1	0.136
Igf2	insulin-like growth factor 2	0.135	Mouse
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.130
Stat3	signal transducer and activator of transcription 3	0.129
Sox9	SRY-box containing gene 9	0.127
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.125
Fcgr1	Fc receptor, IgG, high affinity I	0.125
Evl	Ena-vasodilator stimulated phosphoprotein	0.122	Mouse
Sfrp2	secreted frizzled-related protein 2	0.117
Ghr	growth hormone receptor	0.114
Il1r1	interleukin 1 receptor, type I	0.114
Il6st	interleukin 6 signal transducer	0.114
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.111
Il10	interleukin 10	0.111
Ptpre	protein tyrosine phosphatase, receptor type, E	0.111
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.111
Mrc1	mannose receptor, C type 1	0.109
Zeb1	zinc finger E-box binding homeobox 1	0.107
Gsk3b	glycogen synthase kinase 3 beta	0.105	Rat Fly
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.105
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.104
Fgfr1	fibroblast growth factor receptor 1	0.103
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.103	Fly
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.103
Braf	Braf transforming gene	0.100
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.100
Dlg1	discs, large homolog 1 (Drosophila)	0.099
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.099
Ret	ret proto-oncogene	0.098
Gna11	guanine nucleotide binding protein, alpha 11	0.097
Ilk	integrin linked kinase	0.096
Qk	quaking	0.096
Ldb3	LIM domain binding 3	0.095
Ubc	ubiquitin C	0.094
Casp1	caspase 1	0.094
Tgfbr2	transforming growth factor, beta receptor II	0.094
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.092
Foxc1	forkhead box C1	0.090
Tyrobp	TYRO protein tyrosine kinase binding protein	0.090
Zbtb20	zinc finger and BTB domain containing 20	0.090
Clock	circadian locomotor output cycles kaput	0.090
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.089
C3ar1	complement component 3a receptor 1	0.089
Hif1a	hypoxia inducible factor 1, alpha subunit	0.087
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.087
Unc93b1	unc-93 homolog B1 (C. elegans)	0.086
Ski	ski sarcoma viral oncogene homolog (avian)	0.086
Cd22	CD22 antigen	0.086
Efnb2	ephrin B2	0.084
Flii	flightless I homolog (Drosophila)	0.084
Homer1	homer homolog 1 (Drosophila)	0.083
Ptch1	patched homolog 1	0.082
Nf1	neurofibromatosis 1	0.081
Rac1	RAS-related C3 botulinum substrate 1	0.079
Gab2	growth factor receptor bound protein 2-associated protein 2	0.079
Aif1	allograft inflammatory factor 1	0.079
Plcg2	phospholipase C, gamma 2	0.079
Sfrp1	secreted frizzled-related protein 1	0.077
Pycard	PYD and CARD domain containing	0.076
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.076
Igf1r	insulin-like growth factor I receptor	0.076
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.076
Stag2	stromal antigen 2	0.075
Cd86	CD86 antigen	0.075	Mouse
Trp73	transformation related protein 73	0.075
Tcra	T-cell receptor alpha chain	0.073
Parva	parvin, alpha	0.072
Axl	AXL receptor tyrosine kinase	0.072
Ptgir	prostaglandin I receptor (IP)	0.072
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.072
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.071
Tgfbr1	transforming growth factor, beta receptor I	0.070
Blnk	B-cell linker	0.070
Cd68	CD68 antigen	0.069
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.068
Dok2	docking protein 2	0.068
Ikbkg	inhibitor of kappaB kinase gamma	0.068
Larp4b	La ribonucleoprotein domain family, member 4B	0.067
Ahr	aryl-hydrocarbon receptor	0.067
Jak1	Janus kinase 1	0.067
Sirpa	signal-regulatory protein alpha	0.066
Vav1	vav 1 oncogene	0.066
Rasgrp1	RAS guanyl releasing protein 1	0.066
Arl4c	ADP-ribosylation factor-like 4C	0.066
Src	Rous sarcoma oncogene	0.065	Mouse
Lrp10	low-density lipoprotein receptor-related protein 10	0.065
Prrx1	paired related homeobox 1	0.063
Il22	interleukin 22	0.063
Ikzf1	IKAROS family zinc finger 1	0.063
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.063	Mouse
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.062
Shank2	SH3/ankyrin domain gene 2	0.061
Fgfr3	fibroblast growth factor receptor 3	0.061
Clec4n	C-type lectin domain family 4, member n	0.060
Prnp	prion protein	0.060
Arrb2	arrestin, beta 2	0.060
Notch1	Notch gene homolog 1 (Drosophila)	0.060
Lasp1	LIM and SH3 protein 1	0.059
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.059
Pthlh	parathyroid hormone-like peptide	0.058
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.058
Igf2r	insulin-like growth factor 2 receptor	0.058
Lepr	leptin receptor	0.057
Itgb2	integrin beta 2	0.057
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.057
Itga6	integrin alpha 6	0.056
Noto	notochord homolog (Xenopus laevis)	0.056
Rasa1	RAS p21 protein activator 1	0.056
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.055
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.055
Raf1	v-raf-leukemia viral oncogene 1	0.054
Jak2	Janus kinase 2	0.054
Dusp6	dual specificity phosphatase 6	0.054	Human Mouse Rat Fly
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.054
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.054
Crebbp	CREB binding protein	0.054
Vangl2	vang-like 2 (van gogh, Drosophila)	0.054
Pparg	peroxisome proliferator activated receptor gamma	0.053
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.053
Maf1	MAF1 homolog (S. cerevisiae)	0.053
Btg2	B-cell translocation gene 2, anti-proliferative	0.053
Rtn4r	reticulon 4 receptor	0.053
Ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)	0.053
Marco	macrophage receptor with collagenous structure	0.053
Fgfr2	fibroblast growth factor receptor 2	0.053
Ifna1	interferon alpha 1	0.053
App	amyloid beta (A4) precursor protein	0.051
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.051
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.051
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.050
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.050	Mouse
Nos2	nitric oxide synthase 2, inducible	0.050
Dnm1	dynamin 1	0.049
Rnf11	ring finger protein 11	0.049
Stk4	serine/threonine kinase 4	0.049
Ooep	oocyte expressed protein homolog (dog)	0.049
Cd40	CD40 antigen	0.049
Myd88	myeloid differentiation primary response gene 88	0.049
Cit	citron	0.049
Zic3	zinc finger protein of the cerebellum 3	0.049
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.049
Ptp4a2	protein tyrosine phosphatase 4a2	0.049
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.048
Dusp1	dual specificity phosphatase 1	0.048	Human Mouse
Cd300ld	CD300 molecule-like family member d	0.048
Il1a	interleukin 1 alpha	0.048	Mouse
Runx1	runt related transcription factor 1	0.047
Ctss	cathepsin S	0.047
Junb	Jun-B oncogene	0.047
Rora	RAR-related orphan receptor alpha	0.047
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.046
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.046
Wdr1	WD repeat domain 1	0.046
Lcp2	lymphocyte cytosolic protein 2	0.046
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.046
Actn1	actinin, alpha 1	0.046
Daxx	Fas death domain-associated protein	0.046
Ncam1	neural cell adhesion molecule 1	0.046
March7	membrane-associated ring finger (C3HC4) 7	0.046
Thbs1	thrombospondin 1	0.046
Cxcl2	chemokine (C-X-C motif) ligand 2	0.046
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.046
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.045
Ptprn	protein tyrosine phosphatase, receptor type, N	0.045
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.045
Lef1	lymphoid enhancer binding factor 1	0.045
Egr2	early growth response 2	0.045	Worm
Lair1	leukocyte-associated Ig-like receptor 1	0.045
Nab2	Ngfi-A binding protein 2	0.045
Il2rg	interleukin 2 receptor, gamma chain	0.045
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.044
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.044
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.044
Folr2	folate receptor 2 (fetal)	0.044
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.044
Gng12	guanine nucleotide binding protein (G protein), gamma 12	0.044
Cdx2	caudal type homeobox 2	0.044
Impad1	inositol monophosphatase domain containing 1	0.044
Msl1	male-specific lethal 1 homolog (Drosophila)	0.043
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.043
Kitl	kit ligand	0.043
Ptprq	protein tyrosine phosphatase, receptor type, Q	0.043	Mouse
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.043
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.042
Bcar1	breast cancer anti-estrogen resistance 1	0.042
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.042
Smad3	MAD homolog 3 (Drosophila)	0.042
Mef2a	myocyte enhancer factor 2A	0.041
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.041
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.041
Mefv	Mediterranean fever	0.041
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.041
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.041
Pdcd1	programmed cell death 1	0.041
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.041
Dbnl	drebrin-like	0.041
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.041
Nrxn3	neurexin III	0.040
Pum2	pumilio 2 (Drosophila)	0.040	Worm
Peli1	pellino 1	0.040
Msr1	macrophage scavenger receptor 1	0.040
Stk11	serine/threonine kinase 11	0.040
Enah	enabled homolog (Drosophila)	0.040	Mouse
Igh	immunoglobulin heavy chain complex	0.039
Birc6	baculoviral IAP repeat-containing 6	0.039
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.039
Ier2	immediate early response 2	0.039
Plek	pleckstrin	0.039
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.039	Mouse
Ptpra	protein tyrosine phosphatase, receptor type, A	0.039
Ralbp1	ralA binding protein 1	0.039
Dsg1a	desmoglein 1 alpha	0.038
Actn4	actinin alpha 4	0.038
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.038
Vcl	vinculin	0.038
Hcls1	hematopoietic cell specific Lyn substrate 1	0.038
Nbn	nibrin	0.038
Cx3cr1	chemokine (C-X3-C) receptor 1	0.038
Arrb1	arrestin, beta 1	0.038
Wac	WW domain containing adaptor with coiled-coil	0.038
Ncoa1	nuclear receptor coactivator 1	0.038
Cdc42se1	CDC42 small effector 1	0.038
Cenpj	centromere protein J	0.038
Tlr6	toll-like receptor 6	0.038	Mouse
Runx2	runt related transcription factor 2	0.037
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.037
Cul4a	cullin 4A	0.037
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.037
Egfr	epidermal growth factor receptor	0.037
Scn8a	sodium channel, voltage-gated, type VIII, alpha	0.037
Siah2	seven in absentia 2	0.037
Socs3	suppressor of cytokine signaling 3	0.037
C1qb	complement component 1, q subcomponent, beta polypeptide	0.036	Mouse
Klf4	Kruppel-like factor 4 (gut)	0.036
Rpe65	retinal pigment epithelium 65	0.036
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.036
Notch3	Notch gene homolog 3 (Drosophila)	0.036
Wnt5a	wingless-related MMTV integration site 5A	0.036
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.036
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.035
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.035
Tmem64	transmembrane protein 64	0.035
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.035
Scg3	secretogranin III	0.035
Msh2	mutS homolog 2 (E. coli)	0.035
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.035
Aim2	absent in melanoma 2	0.035
Frs2	fibroblast growth factor receptor substrate 2	0.035
Smad1	MAD homolog 1 (Drosophila)	0.035
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.035
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.035
Ednrb	endothelin receptor type B	0.035
Ins2	insulin II	0.035	Mouse
Mapk3	mitogen-activated protein kinase 3	0.035	Yeast
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.035
Kif19a	kinesin family member 19A	0.035
Ncf1	neutrophil cytosolic factor 1	0.034
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.034
Bmp2	bone morphogenetic protein 2	0.034
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.034
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.034
Fcrls	Fc receptor-like S, scavenger receptor	0.034
Rbl2	retinoblastoma-like 2	0.034
Rab12	RAB12, member RAS oncogene family	0.034
Was	Wiskott-Aldrich syndrome homolog (human)	0.034
Gltp	glycolipid transfer protein	0.034
AF251705	cDNA sequence AF251705	0.034
Cd5	CD5 antigen	0.033
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.033
Ccr6	chemokine (C-C motif) receptor 6	0.033
Tcf7	transcription factor 7, T-cell specific	0.033
Actn2	actinin alpha 2	0.033
Plcg1	phospholipase C, gamma 1	0.033
Prkcd	protein kinase C, delta	0.033	Human
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.033
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.032
Ins1	insulin I	0.032	Mouse
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.032
Egr1	early growth response 1	0.032	Worm
Ikbkb	inhibitor of kappaB kinase beta	0.032
Zfp871	zinc finger protein 871	0.032
Nab1	Ngfi-A binding protein 1	0.032
Ina	internexin neuronal intermediate filament protein, alpha	0.032
Rfwd2	ring finger and WD repeat domain 2	0.032
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.032	Fly
Cybb	cytochrome b-245, beta polypeptide	0.032
Dok3	docking protein 3	0.032
Il18rap	interleukin 18 receptor accessory protein	0.032
Kif3a	kinesin family member 3A	0.032
Ube3a	ubiquitin protein ligase E3A	0.032
Gsta4	glutathione S-transferase, alpha 4	0.031	Mouse
Ptprj	protein tyrosine phosphatase, receptor type, J	0.031
Rc3h1	RING CCCH (C3H) domains 1	0.031
Fgf7	fibroblast growth factor 7	0.031
Mcoln2	mucolipin 2	0.031
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.031
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.031
Cd180	CD180 antigen	0.031	Mouse
Nlk	nemo like kinase	0.031
Mpeg1	macrophage expressed gene 1	0.031
Ccr1	chemokine (C-C motif) receptor 1	0.031
Brd4	bromodomain containing 4	0.031
Wnt10a	wingless related MMTV integration site 10a	0.031
Pld4	phospholipase D family, member 4	0.031
Tsc2	tuberous sclerosis 2	0.031	Rat
Marcksl1	MARCKS-like 1	0.031
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.030
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.030
Pnpla2	patatin-like phospholipase domain containing 2	0.030
Csnk1e	casein kinase 1, epsilon	0.030
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.030
Traf3ip2	TRAF3 interacting protein 2	0.030
Emx1	empty spiracles homolog 1 (Drosophila)	0.030
Npepps	aminopeptidase puromycin sensitive	0.030
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.030
Prdx6	peroxiredoxin 6	0.030
Ankrd17	ankyrin repeat domain 17	0.030
Tifa	TRAF-interacting protein with forkhead-associated domain	0.030
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.030
Eln	elastin	0.030
Myo10	myosin X	0.030
Rasa3	RAS p21 protein activator 3	0.030
Sharpin	SHANK-associated RH domain interacting protein	0.030
Bcl3	B-cell leukemia/lymphoma 3	0.030
Fam105a	family with sequence similarity 105, member A	0.029
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.029
Vdr	vitamin D receptor	0.029
Itga3	integrin alpha 3	0.029
Laptm5	lysosomal-associated protein transmembrane 5	0.029
Prkcz	protein kinase C, zeta	0.029
L1cam	L1 cell adhesion molecule	0.029
Slamf8	SLAM family member 8	0.029
Phlda1	pleckstrin homology-like domain, family A, member 1	0.029
Aplp2	amyloid beta (A4) precursor-like protein 2	0.029
Rel	reticuloendotheliosis oncogene	0.029
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.029
Niacr1	niacin receptor 1	0.029
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.029
Adrbk1	adrenergic receptor kinase, beta 1	0.029
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.029
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.029
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.029
Cul9	cullin 9	0.029
Gstk1	glutathione S-transferase kappa 1	0.029
Mast2	microtubule associated serine/threonine kinase 2	0.029
Abi1	abl-interactor 1	0.029
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.029
Syn2	synapsin II	0.029
Mapk7	mitogen-activated protein kinase 7	0.029
Cd52	CD52 antigen	0.029
Ifngr1	interferon gamma receptor 1	0.028
Sav1	salvador homolog 1 (Drosophila)	0.028
Ids	iduronate 2-sulfatase	0.028
Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	0.028
Il18	interleukin 18	0.028
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.028
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.028	Mouse
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.028
Tbl1x	transducin (beta)-like 1 X-linked	0.028
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.028
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.028
Ptgds	prostaglandin D2 synthase (brain)	0.028
March6	membrane-associated ring finger (C3HC4) 6	0.028
Zfr	zinc finger RNA binding protein	0.028
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.028
Hspa1b	heat shock protein 1B	0.028
Becn1	beclin 1, autophagy related	0.028
Nradd	neurotrophin receptor associated death domain	0.028
Cdh6	cadherin 6	0.028
Ccndbp1	cyclin D-type binding-protein 1	0.028
Cd33	CD33 antigen	0.028
BC013712	cDNA sequence BC013712	0.028
Smad6	MAD homolog 6 (Drosophila)	0.028
Mfhas1	malignant fibrous histiocytoma amplified sequence 1	0.028
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.028
Lrp6	low density lipoprotein receptor-related protein 6	0.028
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.027
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.027
Sh2b2	SH2B adaptor protein 2	0.027
Errfi1	ERBB receptor feedback inhibitor 1	0.027
Rdh10	retinol dehydrogenase 10 (all-trans)	0.027
Gstm1	glutathione S-transferase, mu 1	0.027
Grik4	glutamate receptor, ionotropic, kainate 4	0.027
Vav2	vav 2 oncogene	0.027
Zfp644	zinc finger protein 644	0.027
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.027
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.027
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.027
Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.027
Sik3	SIK family kinase 3	0.027
Irak4	interleukin-1 receptor-associated kinase 4	0.027
Dda1	DET1 and DDB1 associated 1	0.027
Pxn	paxillin	0.027
Hexb	hexosaminidase B	0.027
Kif1b	kinesin family member 1B	0.027
Wbp2	WW domain binding protein 2	0.026
Sos1	son of sevenless homolog 1 (Drosophila)	0.026	Mouse
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.026
Tyro3	TYRO3 protein tyrosine kinase 3	0.026
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.026
Wwtr1	WW domain containing transcription regulator 1	0.026
Hbegf	heparin-binding EGF-like growth factor	0.026
Darc	Duffy blood group, chemokine receptor	0.026
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.026
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.026
Lpin1	lipin 1	0.026
Csnk1d	casein kinase 1, delta	0.026
Cdk14	cyclin-dependent kinase 14	0.026
Rhob	ras homolog gene family, member B	0.026
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.026
Dlg2	discs, large homolog 2 (Drosophila)	0.026
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.026	Fly
Zc3h11a	zinc finger CCCH type containing 11A	0.026
Ctnnd2	catenin (cadherin associated protein), delta 2	0.026
Asprv1	aspartic peptidase, retroviral-like 1	0.026
Men1	multiple endocrine neoplasia 1	0.026	Human Fly
Camk4	calcium/calmodulin-dependent protein kinase IV	0.026
Gja1	gap junction protein, alpha 1	0.026
Ddx54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	0.026
Csrnp1	cysteine-serine-rich nuclear protein 1	0.026
Taok1	TAO kinase 1	0.026
Cdk4	cyclin-dependent kinase 4	0.026
Ubr3	ubiquitin protein ligase E3 component n-recognin 3	0.025
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.025
Ebi3	Epstein-Barr virus induced gene 3	0.025
Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.025
Resp18	regulated endocrine-specific protein 18	0.025
Zfp42	zinc finger protein 42	0.025
Zswim6	zinc finger, SWIM domain containing 6	0.025
Cdh1	cadherin 1	0.025
Klf13	Kruppel-like factor 13	0.025
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.025
Cd247	CD247 antigen	0.025
Arrdc3	arrestin domain containing 3	0.025
Skap2	src family associated phosphoprotein 2	0.025
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.025
Dhrs2	dehydrogenase/reductase member 2	0.025
Sept9	septin 9	0.025
Ifnab	interferon alpha B	0.025
Wdfy2	WD repeat and FYVE domain containing 2	0.025
Clec7a	C-type lectin domain family 7, member a	0.025
Irf5	interferon regulatory factor 5	0.025
Prdm1	PR domain containing 1, with ZNF domain	0.025
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.025
Plcd1	phospholipase C, delta 1	0.025
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.025
Arc	activity regulated cytoskeletal-associated protein	0.025
Cntn2	contactin 2	0.025
Msl2	male-specific lethal 2 homolog (Drosophila)	0.025
Shh	sonic hedgehog	0.025
Gpr35	G protein-coupled receptor 35	0.025
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.025
Yap1	yes-associated protein 1	0.024
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.024
Gbp5	guanylate binding protein 5	0.024
Chd2	chromodomain helicase DNA binding protein 2	0.024
Nxph3	neurexophilin 3	0.024
Tpm4	tropomyosin 4	0.024
Htatip2	HIV-1 tat interactive protein 2, homolog (human)	0.024
Trp53bp1	transformation related protein 53 binding protein 1	0.024
Il1f9	interleukin 1 family, member 9	0.024
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.024
Smad2	MAD homolog 2 (Drosophila)	0.024
Hipk1	homeodomain interacting protein kinase 1	0.024	Mouse
Pygo2	pygopus 2	0.024
Ier5	immediate early response 5	0.024
Ccl8	chemokine (C-C motif) ligand 8	0.024
Fosl2	fos-like antigen 2	0.024
Nrg1	neuregulin 1	0.024
Lipa	lysosomal acid lipase A	0.024
Gpr45	G protein-coupled receptor 45	0.024
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)	0.024
Strn3	striatin, calmodulin binding protein 3	0.024
Spata13	spermatogenesis associated 13	0.024
Cdh13	cadherin 13	0.024
Expi	extracellular proteinase inhibitor	0.024
Dusp4	dual specificity phosphatase 4	0.024	Mouse Rat
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.024
Dst	dystonin	0.024
Myo1c	myosin IC	0.024
Evi2a	ecotropic viral integration site 2a	0.024
Caly	calcyon neuron-specific vesicular protein	0.024
Adcy7	adenylate cyclase 7	0.024
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.024
Igbp1b	immunoglobulin (CD79A) binding protein 1b	0.024
Chrm3	cholinergic receptor, muscarinic 3, cardiac	0.023
Lrrc8c	leucine rich repeat containing 8 family, member C	0.023
Mbnl1	muscleblind-like 1 (Drosophila)	0.023
Tm6sf1	transmembrane 6 superfamily member 1	0.023
Snrk	SNF related kinase	0.023
Rab6	RAB6, member RAS oncogene family	0.023
Cd28	CD28 antigen	0.023
Tmem121	transmembrane protein 121	0.023
Wipf1	WAS/WASL interacting protein family, member 1	0.023
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.023
Bmp5	bone morphogenetic protein 5	0.023
Ctsk	cathepsin K	0.023
Smad7	MAD homolog 7 (Drosophila)	0.023
Ptrf	polymerase I and transcript release factor	0.023
Mapkapk2	MAP kinase-activated protein kinase 2	0.023
Itga1	integrin alpha 1	0.023
Ptplad2	protein tyrosine phosphatase-like A domain containing 2	0.023
Myo15	myosin XV	0.023
Trem3	triggering receptor expressed on myeloid cells 3	0.023
Dsg4	desmoglein 4	0.023
Cdh8	cadherin 8	0.023
Rbms1	RNA binding motif, single stranded interacting protein 1	0.023
Rgs10	regulator of G-protein signalling 10	0.023	Mouse
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.023
Coro1a	coronin, actin binding protein 1A	0.023
Thra	thyroid hormone receptor alpha	0.023
Iqgap1	IQ motif containing GTPase activating protein 1	0.023
Klhl24	kelch-like 24 (Drosophila)	0.023
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.023
Ptprg	protein tyrosine phosphatase, receptor type, G	0.023
Arpp21	cyclic AMP-regulated phosphoprotein, 21	0.023
Matk	megakaryocyte-associated tyrosine kinase	0.023
Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.023
Rhog	ras homolog gene family, member G	0.022
Gatm	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.022
Dusp2	dual specificity phosphatase 2	0.022	Mouse
Gjc2	gap junction protein, gamma 2	0.022
Loxl1	lysyl oxidase-like 1	0.022
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.022
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.022
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.022
Bmper	BMP-binding endothelial regulator	0.022
Nfam1	Nfat activating molecule with ITAM motif 1	0.022
Stim1	stromal interaction molecule 1	0.022
Stmn4	stathmin-like 4	0.022
Gpc3	glypican 3	0.022
Huwe1	HECT, UBA and WWE domain containing 1	0.022
Ache	acetylcholinesterase	0.022
Macf1	microtubule-actin crosslinking factor 1	0.022
Zfp36	zinc finger protein 36	0.022
Klf6	Kruppel-like factor 6	0.022
Pdcd1lg2	programmed cell death 1 ligand 2	0.022	Mouse
Trp63	transformation related protein 63	0.022	Mouse
Dusp26	dual specificity phosphatase 26 (putative)	0.022	Human Yeast
E2f1	E2F transcription factor 1	0.022
Chi3l1	chitinase 3-like 1	0.022
Whrn	whirlin	0.022
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.022
Ctdnep1	CTD nuclear envelope phosphatase 1	0.022
S100a3	S100 calcium binding protein A3	0.022
Pvalb	parvalbumin	0.022
Zcchc14	zinc finger, CCHC domain containing 14	0.022
Cd3e	CD3 antigen, epsilon polypeptide	0.022
Spp1	secreted phosphoprotein 1	0.021
Th	tyrosine hydroxylase	0.021
Dgcr2	DiGeorge syndrome critical region gene 2	0.021
Fxyd1	FXYD domain-containing ion transport regulator 1	0.021
Ccr7	chemokine (C-C motif) receptor 7	0.021
Socs2	suppressor of cytokine signaling 2	0.021
Sox10	SRY-box containing gene 10	0.021
Oxct2a	3-oxoacid CoA transferase 2A	0.021
Numb	numb gene homolog (Drosophila)	0.021
Cd300lf	CD300 antigen like family member F	0.021
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.021
Etv5	ets variant gene 5	0.021
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.021
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.021
Pou3f1	POU domain, class 3, transcription factor 1	0.021
Dlg3	discs, large homolog 3 (Drosophila)	0.021
Ncr1	natural cytotoxicity triggering receptor 1	0.021
Pdyn	prodynorphin	0.021
Cd72	CD72 antigen	0.021
Akt1	thymoma viral proto-oncogene 1	0.021	Rat
Bmp4	bone morphogenetic protein 4	0.021	Human
Hr	hairless	0.021
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.021	Human
Coro1c	coronin, actin binding protein 1C	0.021
Foxo1	forkhead box O1	0.021	Human
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.021
Mark2	MAP/microtubule affinity-regulating kinase 2	0.021
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.021
Ctnnd1	catenin (cadherin associated protein), delta 1	0.021
Efna3	ephrin A3	0.021
Scamp2	secretory carrier membrane protein 2	0.021
Grn	granulin	0.021
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.021
Traf3	TNF receptor-associated factor 3	0.021
Ephb2	Eph receptor B2	0.021
Ppp2r5a	protein phosphatase 2, regulatory subunit B (B56), alpha isoform	0.021
Slmap	sarcolemma associated protein	0.021
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.021
Cd36	CD36 antigen	0.021
Clstn1	calsyntenin 1	0.021
Cfp	complement factor properdin	0.020
Tert	telomerase reverse transcriptase	0.020
Brca1	breast cancer 1	0.020
Klf10	Kruppel-like factor 10	0.020
Nckap1l	NCK associated protein 1 like	0.020
Rgs5	regulator of G-protein signaling 5	0.020	Mouse
Celf6	CUGBP, Elav-like family member 6	0.020
Myc	myelocytomatosis oncogene	0.020
Add1	adducin 1 (alpha)	0.020
Lmna	lamin A	0.020
Plau	plasminogen activator, urokinase	0.020
Gtf2i	general transcription factor II I	0.020
Mff	mitochondrial fission factor	0.020
Med1	mediator complex subunit 1	0.020
Myh10	myosin, heavy polypeptide 10, non-muscle	0.020
Syngr1	synaptogyrin 1	0.020
Hck	hemopoietic cell kinase	0.020	Mouse
Gsta3	glutathione S-transferase, alpha 3	0.020	Mouse
Myo7a	myosin VIIA	0.020
Brs3	bombesin-like receptor 3	0.020
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.020
Fam83f	family with sequence similarity 83, member F	0.020
Galntl5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5	0.020
Bcl10	B-cell leukemia/lymphoma 10	0.020
Acvr2a	activin receptor IIA	0.020
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.020
Triobp	TRIO and F-actin binding protein	0.020
Rap2c	RAP2C, member of RAS oncogene family	0.020
Col4a1	collagen, type IV, alpha 1	0.020
Midn	midnolin	0.020
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.020
Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.020
Krt1	keratin 1	0.020
Lum	lumican	0.020
Fam126b	family with sequence similarity 126, member B	0.020
Syt13	synaptotagmin XIII	0.020
4921517D21Rik	RIKEN cDNA 4921517D21 gene	0.020
Rab10	RAB10, member RAS oncogene family	0.020
Spns1	spinster homolog 1 (Drosophila)	0.020
Pdcd6ip	programmed cell death 6 interacting protein	0.020
Arhgap1	Rho GTPase activating protein 1	0.019
Prkca	protein kinase C, alpha	0.019
Selplg	selectin, platelet (p-selectin) ligand	0.019
Soat1	sterol O-acyltransferase 1	0.019
Siglece	sialic acid binding Ig-like lectin E	0.019
Usp2	ubiquitin specific peptidase 2	0.019
Fam65b	family with sequence similarity 65, member B	0.019
Ifnar1	interferon (alpha and beta) receptor 1	0.019
Irg1	immunoresponsive gene 1	0.019
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.019
Twf2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.019
Grk6	G protein-coupled receptor kinase 6	0.019
Irak3	interleukin-1 receptor-associated kinase 3	0.019
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.019
Fam13b	family with sequence similarity 13, member B	0.019
Myo6	myosin VI	0.019
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.019
Actb	actin, beta	0.019
Ptgfrn	prostaglandin F2 receptor negative regulator	0.019
Timp1	tissue inhibitor of metalloproteinase 1	0.019
Tnrc6b	trinucleotide repeat containing 6b	0.019
Gli3	GLI-Kruppel family member GLI3	0.019
Nrip1	nuclear receptor interacting protein 1	0.019
Grm5	glutamate receptor, metabotropic 5	0.019
Rassf2	Ras association (RalGDS/AF-6) domain family member 2	0.019
Gna12	guanine nucleotide binding protein, alpha 12	0.019
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.019
Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit	0.019
Plcb1	phospholipase C, beta 1	0.019
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.019
Naip6	NLR family, apoptosis inhibitory protein 6	0.019
Mfsd6l	major facilitator superfamily domain containing 6-like	0.019
Fndc1	fibronectin type III domain containing 1	0.019
Mt3	metallothionein 3	0.019
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.019
C78339	expressed sequence C78339	0.019
Shc3	src homology 2 domain-containing transforming protein C3	0.019
Uts2r	urotensin 2 receptor	0.019