IMP: Integrative Multi-species Prediction

Mus musculus

12 genes annotated in mouse

Multi-species View

melanosome localization

GO:0032400

Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "melanosome localization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "melanosome localization" (in gray)

Name	Description	Probability	Func Analog Organism
Bbs4	Bardet-Biedl syndrome 4 (human)	1.000	Zebrafish
Lyst	lysosomal trafficking regulator	1.000
Bbs2	Bardet-Biedl syndrome 2 (human)	0.998	Zebrafish
Bbs1	Bardet-Biedl syndrome 1 (human)	0.998
Rab27a	RAB27A, member RAS oncogene family	0.997
a	nonagouti	0.991
Mitf	microphthalmia-associated transcription factor	0.984
Cno	cappuccino	0.958
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.922
Pldn	pallidin	0.911	Human
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.865
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.865
Tyrp1	tyrosinase-related protein 1	0.773
Tyr	tyrosinase	0.749
Rab11a	RAB11a, member RAS oncogene family	0.647
Mlph	melanophilin	0.627
Arl6	ADP-ribosylation factor-like 6	0.623	Zebrafish
Oca2	oculocutaneous albinism II	0.610
Stx12	syntaxin 12	0.555
Hps6	Hermansky-Pudlak syndrome 6	0.534
Vapa	vesicle-associated membrane protein, associated protein A	0.349
Exoc7	exocyst complex component 7	0.341
Atp6v1c1	ATPase, H+ transporting, lysosomal V1 subunit C1	0.338
Csnk1g2	casein kinase 1, gamma 2	0.300
Prr15	proline rich 15	0.290
Rheb	Ras homolog enriched in brain	0.245
Bbs5	Bardet-Biedl syndrome 5 (human)	0.234
Mlf2	myeloid leukemia factor 2	0.232
Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	0.228
Ttc8	tetratricopeptide repeat domain 8	0.211
Rab5a	RAB5A, member RAS oncogene family	0.196	Mouse
Sh3glb2	SH3-domain GRB2-like endophilin B2	0.167
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.148
Vamp4	vesicle-associated membrane protein 4	0.139
Fkbp8	FK506 binding protein 8	0.136
Aes	amino-terminal enhancer of split	0.123
Dctn2	dynactin 2	0.122
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.120
Hps3	Hermansky-Pudlak syndrome 3 homolog (human)	0.119
Muted	muted	0.111
Add1	adducin 1 (alpha)	0.109
Ppp5c	protein phosphatase 5, catalytic subunit	0.104
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.101
Rab38	RAB38, member of RAS oncogene family	0.098
Bbs9	Bardet-Biedl syndrome 9 (human)	0.096
Stx7	syntaxin 7	0.092
Pef1	penta-EF hand domain containing 1	0.087
Nptn	neuroplastin	0.081
Mc1r	melanocortin 1 receptor	0.077
Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.066
Mapk3	mitogen-activated protein kinase 3	0.063
Btbd10	BTB (POZ) domain containing 10	0.058
Ap2m1	adaptor protein complex AP-2, mu1	0.057
Rab6	RAB6, member RAS oncogene family	0.057
Rnf167	ring finger protein 167	0.055
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.054
Atp6v1d	ATPase, H+ transporting, lysosomal V1 subunit D	0.054
Pacrg	PARK2 co-regulated	0.054
Klhl2	kelch-like 2, Mayven (Drosophila)	0.051
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.051
Ubl7	ubiquitin-like 7 (bone marrow stromal cell-derived)	0.050
Rnf103	ring finger protein 103	0.050
Ccdc64	coiled-coil domain containing 64	0.050
Fbxw5	F-box and WD-40 domain protein 5	0.050
C78339	expressed sequence C78339	0.049
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.049
Grb7	growth factor receptor bound protein 7	0.049
Chmp1b	chromatin modifying protein 1B	0.045
Myo5a	myosin VA	0.044
Pde8b	phosphodiesterase 8B	0.043
Pmel	premelanosome protein	0.042
Dstn	destrin	0.041
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.041
Dctn1	dynactin 1	0.040
Akirin1	akirin 1	0.039
Wwox	WW domain-containing oxidoreductase	0.038
Cldn2	claudin 2	0.037
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.037
Anapc2	anaphase promoting complex subunit 2	0.036
Rnf11	ring finger protein 11	0.036
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.036
Spna2	spectrin alpha 2	0.035
Ndfip1	Nedd4 family interacting protein 1	0.035
Sntb1	syntrophin, basic 1	0.035
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.035
Sox15	SRY-box containing gene 15	0.033
Rab25	RAB25, member RAS oncogene family	0.032	Mouse
Med16	mediator complex subunit 16	0.032
Bloc1s3	biogenesis of lysosome-related organelles complex-1, subunit 3	0.031
Obfc2b	oligonucleotide/oligosaccharide-binding fold containing 2B	0.030
Kit	kit oncogene	0.030
Lep	leptin	0.030
Chmp5	chromatin modifying protein 5	0.030
Slc24a5	solute carrier family 24, member 5	0.029
2410004B18Rik	RIKEN cDNA 2410004B18 gene	0.029
Arf4	ADP-ribosylation factor 4	0.028
Calm1	calmodulin 1	0.028
Chmp2b	chromatin modifying protein 2B	0.028
Akap8l	A kinase (PRKA) anchor protein 8-like	0.027
Ehf	ets homologous factor	0.027
Rab2a	RAB2A, member RAS oncogene family	0.027
Chmp4b	chromatin modifying protein 4B	0.027
Arl1	ADP-ribosylation factor-like 1	0.027
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.027
Pitpna	phosphatidylinositol transfer protein, alpha	0.027
Itfg1	integrin alpha FG-GAP repeat containing 1	0.026
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.026
Sec23a	SEC23A (S. cerevisiae)	0.026
Clptm1	cleft lip and palate associated transmembrane protein 1	0.026
Prf1	perforin 1 (pore forming protein)	0.025
Wbp2	WW domain binding protein 2	0.025
Elf3	E74-like factor 3	0.024
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.024
Lad1	ladinin	0.024
Usp5	ubiquitin specific peptidase 5 (isopeptidase T)	0.024
Golga7	golgi autoantigen, golgin subfamily a, 7	0.024
Nipsnap3b	nipsnap homolog 3B (C. elegans)	0.023
Pomc	pro-opiomelanocortin-alpha	0.023	Zebrafish
Npy6r	neuropeptide Y receptor Y6	0.023
Bag6	BCL2-associated athanogene 6	0.023
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.022
Pfn2	profilin 2	0.021
Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)	0.021
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.020
Nckap1	NCK-associated protein 1	0.019
Mapk13	mitogen-activated protein kinase 13	0.019
Slc25a10	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10	0.019
Glrb	glycine receptor, beta subunit	0.019
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.019
Cdcp1	CUB domain containing protein 1	0.019
Ssbp4	single stranded DNA binding protein 4	0.018
Pmm1	phosphomannomutase 1	0.018
Rdh10	retinol dehydrogenase 10 (all-trans)	0.018
Sytl5	synaptotagmin-like 5	0.018
Chmp1a	chromatin modifying protein 1A	0.018
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.017
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.017
Golga2	golgi autoantigen, golgin subfamily a, 2	0.016
Vipr1	vasoactive intestinal peptide receptor 1	0.016
Rabac1	Rab acceptor 1 (prenylated)	0.016
Cby1	chibby homolog 1 (Drosophila)	0.016
Tsc2	tuberous sclerosis 2	0.016
Nrbf2	nuclear receptor binding factor 2	0.016
Mtmr6	myotubularin related protein 6	0.016
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.016
Pdcd10	programmed cell death 10	0.016
3110043O21Rik	RIKEN cDNA 3110043O21 gene	0.016
Rhob	ras homolog gene family, member B	0.016
Ift74	intraflagellar transport 74 homolog (Chlamydomonas)	0.016
Max	Max protein	0.016
Rragc	Ras-related GTP binding C	0.015
Bbs7	Bardet-Biedl syndrome 7 (human)	0.015
Zfpl1	zinc finger like protein 1	0.015
Slc45a2	solute carrier family 45, member 2	0.015
Car12	carbonic anyhydrase 12	0.015
Cldn3	claudin 3	0.015
Arhgap1	Rho GTPase activating protein 1	0.015
Lrrc68	leucine rich repeat containing 68	0.015
Mkks	McKusick-Kaufman syndrome protein	0.015	Zebrafish
Fmn1	formin 1	0.015
AI837181	expressed sequence AI837181	0.015
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.014
Pex5	peroxisomal biogenesis factor 5	0.014
Cyth2	cytohesin 2	0.014
Fbxo33	F-box protein 33	0.014
Vps4a	vacuolar protein sorting 4a (yeast)	0.014
Golph3	golgi phosphoprotein 3	0.014
Capn5	calpain 5	0.014
Mapre3	microtubule-associated protein, RP/EB family, member 3	0.014
Zfp954	zinc finger protein 954	0.014
Rnf115	ring finger protein 115	0.014
Tusc3	tumor suppressor candidate 3	0.014
Bcl7b	B-cell CLL/lymphoma 7B	0.014
Kdelr1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.014
Ppp6r1	protein phosphatase 6, regulatory subunit 1	0.013
Lgals7	lectin, galactose binding, soluble 7	0.013
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.013
Gdi1	guanosine diphosphate (GDP) dissociation inhibitor 1	0.013
Expi	extracellular proteinase inhibitor	0.013
Cldn6	claudin 6	0.013
Usp12	ubiquitin specific peptidase 12	0.013
Syap1	synapse associated protein 1	0.013
Rap1b	RAS related protein 1b	0.013
Wsb2	WD repeat and SOCS box-containing 2	0.013
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.013
Ppp1r2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.013
Oit1	oncoprotein induced transcript 1	0.013
Hdac5	histone deacetylase 5	0.013
Ckmt1	creatine kinase, mitochondrial 1, ubiquitous	0.013
Eid1	EP300 interacting inhibitor of differentiation 1	0.012
Fam188a	family with sequence similarity 188, member A	0.012
Mia1	melanoma inhibitory activity 1	0.012
Trappc10	trafficking protein particle complex 10	0.012
Hspa4l	heat shock protein 4 like	0.012
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.012
Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.012
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.012
Uso1	USO1 homolog, vesicle docking protein (yeast)	0.012
Mal2	mal, T-cell differentiation protein 2	0.012
Arfip1	ADP-ribosylation factor interacting protein 1	0.012
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.012
Taf13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.012
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.012
Cltc	clathrin, heavy polypeptide (Hc)	0.012
Tspyl4	TSPY-like 4	0.012
Prss8	protease, serine, 8 (prostasin)	0.012
Rapsn	receptor-associated protein of the synapse	0.012
Rab1b	RAB1B, member RAS oncogene family	0.012	Mouse
Rala	v-ral simian leukemia viral oncogene homolog A (ras related)	0.012
Gipc1	GIPC PDZ domain containing family, member 1	0.012
Gm16517	predicted gene, Gm16517	0.012
Btbd2	BTB (POZ) domain containing 2	0.011
Ggt1	gamma-glutamyltransferase 1	0.011
Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	0.011
Klraq1	KLRAQ motif containing 1	0.011
Bsg	basigin	0.011
Dbnl	drebrin-like	0.011
Pxk	PX domain containing serine/threonine kinase	0.011
6330409N04Rik	RIKEN cDNA 6330409N04 gene	0.011
Ap1s1	adaptor protein complex AP-1, sigma 1	0.011
Mark2	MAP/microtubule affinity-regulating kinase 2	0.011
Pfkl	phosphofructokinase, liver, B-type	0.011
8430410K20Rik	RIKEN cDNA 8430410K20 gene	0.011
Hoxc8	homeobox C8	0.011
Asb8	ankyrin repeat and SOCS box-containing 8	0.011
Arfrp1	ADP-ribosylation factor related protein 1	0.011
Lamb3	laminin, beta 3	0.011
Fgfbp1	fibroblast growth factor binding protein 1	0.011
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Crb3	crumbs homolog 3 (Drosophila)	0.011
Hmgn3	high mobility group nucleosomal binding domain 3	0.010
1500031L02Rik	RIKEN cDNA 1500031L02 gene	0.010
Mmp16	matrix metallopeptidase 16	0.010
Map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.010
Efhc1	EF-hand domain (C-terminal) containing 1	0.010
Tcfap2b	transcription factor AP-2 beta	0.010
Zfp790	zinc finger protein 790	0.010
Pde9a	phosphodiesterase 9A	0.010
Rab21	RAB21, member RAS oncogene family	0.010	Mouse
Zc3h12d	zinc finger CCCH type containing 12D	0.010
B9d1	B9 protein domain 1	0.010
Soat2	sterol O-acyltransferase 2	0.010
Limk2	LIM motif-containing protein kinase 2	0.010
Stx11	syntaxin 11	0.010