IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

chromatin silencing at rdna

GO:0000183

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chromatin silencing at rdna"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "chromatin silencing at rdna" (in gray)

Name	Description	Probability	Func Analog Organism
Hdac1	histone deacetylase 1	0.970
Arid1a	AT rich interactive domain 1A (SWI-like)	0.741
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.703
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.508
Sin3a	transcriptional regulator, SIN3A (yeast)	0.487	Yeast
Kdm5b	lysine (K)-specific demethylase 5B	0.448
Baz1b	bromodomain adjacent to zinc finger domain, 1B	0.438
Ep400	E1A binding protein p400	0.324
Trp53	transformation related protein 53	0.286
Dmap1	DNA methyltransferase 1-associated protein 1	0.263
Baz1a	bromodomain adjacent to zinc finger domain 1A	0.239
Hdac2	histone deacetylase 2	0.205
Ncor1	nuclear receptor co-repressor 1	0.189
Ctcf	CCCTC-binding factor	0.143
Qrich1	glutamine-rich 1	0.135
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.131
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.126
Sp1	trans-acting transcription factor 1	0.119
Chd4	chromodomain helicase DNA binding protein 4	0.109
Mta2	metastasis-associated gene family, member 2	0.106
Lepr	leptin receptor	0.100
Rnf2	ring finger protein 2	0.092
Rnf220	ring finger protein 220	0.085
Ep300	E1A binding protein p300	0.081
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.079
Arid1b	AT rich interactive domain 1B (SWI-like)	0.079
Cry1	cryptochrome 1 (photolyase-like)	0.075
Hcfc1	host cell factor C1	0.071
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.069
Sox2	SRY-box containing gene 2	0.068
Nanog	Nanog homeobox	0.068
Zfp292	zinc finger protein 292	0.066
Crebbp	CREB binding protein	0.058
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.053
Kdm1a	lysine (K)-specific demethylase 1A	0.051
Rbbp4	retinoblastoma binding protein 4	0.047
Per2	period homolog 2 (Drosophila)	0.045
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.043
Yy1	YY1 transcription factor	0.043
Srsf10	serine/arginine-rich splicing factor 10	0.043
Brd4	bromodomain containing 4	0.042
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.042
Acin1	apoptotic chromatin condensation inducer 1	0.041
Creb1	cAMP responsive element binding protein 1	0.039
Hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.038
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.038
Pum1	pumilio 1 (Drosophila)	0.037
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.037
Usp7	ubiquitin specific peptidase 7	0.037
Ubn1	ubinuclein 1	0.036
Max	Max protein	0.032
Asxl1	additional sex combs like 1 (Drosophila)	0.030
Rspry1	ring finger and SPRY domain containing 1	0.030
Hdac3	histone deacetylase 3	0.029
Fam193a	family with sequence similarity 193, member A	0.029
Epc2	enhancer of polycomb homolog 2 (Drosophila)	0.028
Mga	MAX gene associated	0.027
Pparg	peroxisome proliferator activated receptor gamma	0.026
Kdm6a	4lysine (K)-specific demethylase 6A	0.026
Smc6	structural maintenance of chromosomes 6	0.025
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.025
Rasl11a	RAS-like, family 11, member A	0.025
Rif1	Rap1 interacting factor 1 homolog (yeast)	0.025
Irs2	insulin receptor substrate 2	0.024
Hmgb1	high mobility group box 1	0.023
Sart3	squamous cell carcinoma antigen recognized by T-cells 3	0.023
Tcfcp2l1	transcription factor CP2-like 1	0.023
Pou2f1	POU domain, class 2, transcription factor 1	0.022
E2f1	E2F transcription factor 1	0.022
L3mbtl2	l(3)mbt-like 2 (Drosophila)	0.022
Foxp1	forkhead box P1	0.022
Krit1	KRIT1, ankyrin repeat containing	0.022
Ghr	growth hormone receptor	0.022
Foxo3	forkhead box O3	0.021
Cnot4	CCR4-NOT transcription complex, subunit 4	0.021
Ranbp2	RAN binding protein 2	0.021
Tubgcp2	tubulin, gamma complex associated protein 2	0.021
Safb	scaffold attachment factor B	0.021
Rc3h2	ring finger and CCCH-type zinc finger domains 2	0.021
Ldb1	LIM domain binding 1	0.021
Daxx	Fas death domain-associated protein	0.021
Srsf4	serine/arginine-rich splicing factor 4	0.020
Trrap	transformation/transcription domain-associated protein	0.020
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.020
Srrm1	serine/arginine repetitive matrix 1	0.020
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.020
Terf1	telomeric repeat binding factor 1	0.020
Npc1	Niemann Pick type C1	0.020
Scaf4	SR-related CTD-associated factor 4	0.019
Polr1a	polymerase (RNA) I polypeptide A	0.019
Tcf3	transcription factor 3	0.019
Pcgf1	polycomb group ring finger 1	0.019
Thoc2	THO complex 2	0.019
Topors	topoisomerase I binding, arginine/serine-rich	0.019
Mecp2	methyl CpG binding protein 2	0.019
Cry2	cryptochrome 2 (photolyase-like)	0.019
Setdb1	SET domain, bifurcated 1	0.019
Rest	RE1-silencing transcription factor	0.018
Hnrnpu	heterogeneous nuclear ribonucleoprotein U	0.018
Sap25	sin3 associated polypeptide	0.018
Ylpm1	YLP motif containing 1	0.018
Tet1	tet oncogene 1	0.018
Braf	Braf transforming gene	0.018
Gps2	G protein pathway suppressor 2	0.018
Sap30	sin3 associated polypeptide	0.018
2810474O19Rik	RIKEN cDNA 2810474O19 gene	0.018
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.018
Tcerg1	transcription elongation regulator 1 (CA150)	0.017
Lpar4	lysophosphatidic acid receptor 4	0.017
Chd8	chromodomain helicase DNA binding protein 8	0.017
Rsbn1	rosbin, round spermatid basic protein 1	0.017
Ing3	inhibitor of growth family, member 3	0.017
Ewsr1	Ewing sarcoma breakpoint region 1	0.017
Snw1	SNW domain containing 1	0.017
Rlf	rearranged L-myc fusion sequence	0.017
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.017
Pum2	pumilio 2 (Drosophila)	0.017
Nfya	nuclear transcription factor-Y alpha	0.017
Nipbl	Nipped-B homolog (Drosophila)	0.017
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.017
Vps72	vacuolar protein sorting 72 (yeast)	0.017
Smc1a	structural maintenance of chromosomes 1A	0.017
1110028C15Rik	RIKEN cDNA 1110028C15 gene	0.017
Exoc7	exocyst complex component 7	0.017
Toe1	target of EGR1, member 1 (nuclear)	0.017
Cyth2	cytohesin 2	0.016
Fam117b	family with sequence similarity 117, member B	0.016
Smek2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	0.016
Brd1	bromodomain containing 1	0.016
Dek	DEK oncogene (DNA binding)	0.016
Maml1	mastermind like 1 (Drosophila)	0.016
Mta1	metastasis associated 1	0.016
Tex264	testis expressed gene 264	0.016
Phip	pleckstrin homology domain interacting protein	0.015
Sin3b	transcriptional regulator, SIN3B (yeast)	0.015	Yeast
Ccnl1	cyclin L1	0.015
Plekha5	pleckstrin homology domain containing, family A member 5	0.015
Cxxc1	CXXC finger 1 (PHD domain)	0.015
Whsc2	Wolf-Hirschhorn syndrome candidate 2 (human)	0.015
Trim8	tripartite motif-containing 8	0.015
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.015
Rcor1	REST corepressor 1	0.015
Chd7	chromodomain helicase DNA binding protein 7	0.015
Msl2	male-specific lethal 2 homolog (Drosophila)	0.014
Mnt	max binding protein	0.014
Bod1l	biorientation of chromosomes in cell division 1-like	0.014
Dmtf1	cyclin D binding myb-like transcription factor 1	0.014
Nup153	nucleoporin 153	0.014
Senp1	SUMO1/sentrin specific peptidase 1	0.014
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.014
Wdr5	WD repeat domain 5	0.014
Clock	circadian locomotor output cycles kaput	0.014
Mbtd1	mbt domain containing 1	0.013
Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)	0.013
Ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	0.013
Pcdhb17	protocadherin beta 17	0.013
Tbc1d20	TBC1 domain family, member 20	0.013
Rybp	RING1 and YY1 binding protein	0.013
Brd8	bromodomain containing 8	0.013
Myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.013
E2f4	E2F transcription factor 4	0.013
Pou5f1	POU domain, class 5, transcription factor 1	0.013
Sbno1	sno, strawberry notch homolog 1 (Drosophila)	0.013
Men1	multiple endocrine neoplasia 1	0.012
Mier3	mesoderm induction early response 1, family member 3	0.012
Rb1	retinoblastoma 1	0.012
Epc1	enhancer of polycomb homolog 1 (Drosophila)	0.012
Taf4a	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.012
Dnajc21	DnaJ (Hsp40) homolog, subfamily C, member 21	0.012
Thrap3	thyroid hormone receptor associated protein 3	0.012
Cramp1l	Crm, cramped-like (Drosophila)	0.012
Msh2	mutS homolog 2 (E. coli)	0.012
Pabpn1	poly(A) binding protein, nuclear 1	0.012
Tle3	transducin-like enhancer of split 3, homolog of Drosophila E(spl)	0.012
Etv6	ets variant gene 6 (TEL oncogene)	0.012
Sufu	suppressor of fused homolog (Drosophila)	0.012
Top1	topoisomerase (DNA) I	0.012	Yeast
Tmem115	transmembrane protein 115	0.012
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.012
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.012
Poc1b	POC1 centriolar protein homolog B (Chlamydomonas)	0.012
Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.012
Aqr	aquarius	0.011
Pbx2	pre B-cell leukemia transcription factor 2	0.011
Gtf3c1	general transcription factor III C 1	0.011
Brd2	bromodomain containing 2	0.011
Per1	period homolog 1 (Drosophila)	0.011
Kiss1	KiSS-1 metastasis-suppressor	0.011
Gatad2b	GATA zinc finger domain containing 2B	0.011
Zmym5	zinc finger, MYM-type 5	0.011
Odf2	outer dense fiber of sperm tails 2	0.011
Tnrc6b	trinucleotide repeat containing 6b	0.011
Supt16h	suppressor of Ty 16 homolog (S. cerevisiae)	0.011
Zbtb22	zinc finger and BTB domain containing 22	0.011
Maf1	MAF1 homolog (S. cerevisiae)	0.011
Ptch1	patched homolog 1	0.011
Rbm22	RNA binding motif protein 22	0.010
Bcor	BCL6 interacting corepressor	0.010
Zfp410	zinc finger protein 410	0.010
Rev1	REV1 homolog (S. cerevisiae)	0.010
Ncaph2	non-SMC condensin II complex, subunit H2	0.010
Cbll1	Casitas B-lineage lymphoma-like 1	0.010
Gpbp1	GC-rich promoter binding protein 1	0.010
Numa1	nuclear mitotic apparatus protein 1	0.010
Rcc2	regulator of chromosome condensation 2	0.010
Dpf2	D4, zinc and double PHD fingers family 2	0.010