IMP: Integrative Multi-species Prediction

Mus musculus

74 genes annotated in mouse

negative regulation of proteolysis

Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of proteolysis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of proteolysis" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	0.999
Shh	sonic hedgehog	0.969
Fgfr2	fibroblast growth factor receptor 2	0.900
Gli3	GLI-Kruppel family member GLI3	0.882
Trp63	transformation related protein 63	0.859	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.757
Psen1	presenilin 1	0.730
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.718
Ptgs2	prostaglandin-endoperoxide synthase 2	0.672
Emx1	empty spiracles homolog 1 (Drosophila)	0.657
Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	0.647	Fly
Skil	SKI-like	0.643
Apoa1	apolipoprotein A-I	0.638
Mndal	myeloid nuclear differentiation antigen like	0.631
Fgfr1	fibroblast growth factor receptor 1	0.609
Wnt3a	wingless-related MMTV integration site 3A	0.605	Mouse
Pax3	paired box gene 3	0.597
Otx2	orthodenticle homolog 2 (Drosophila)	0.559
Mdm2	transformed mouse 3T3 cell double minute 2	0.550
Emx2	empty spiracles homolog 2 (Drosophila)	0.534
Fgf8	fibroblast growth factor 8	0.505
Ctla2b	cytotoxic T lymphocyte-associated protein 2 beta	0.491	Fly
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.476	Human Mouse Rat
Hspa1a	heat shock protein 1A	0.465
Esr1	estrogen receptor 1 (alpha)	0.458
Zeb1	zinc finger E-box binding homeobox 1	0.458
Rb1	retinoblastoma 1	0.445
S100a6	S100 calcium binding protein A6 (calcyclin)	0.421
Foxc1	forkhead box C1	0.407
Lyz2	lysozyme 2	0.406
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.406
Axl	AXL receptor tyrosine kinase	0.405
Pthlh	parathyroid hormone-like peptide	0.394
Mdm4	transformed mouse 3T3 cell double minute 4	0.384
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.384
Krt14	keratin 14	0.367
Arrb2	arrestin, beta 2	0.364	Mouse
Pax6	paired box gene 6	0.345
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.342
Plg	plasminogen	0.338
Prkce	protein kinase C, epsilon	0.331
Pten	phosphatase and tensin homolog	0.325
Mmp9	matrix metallopeptidase 9	0.321
Cdk1	cyclin-dependent kinase 1	0.319
Ccne1	cyclin E1	0.316	Fly
Apoe	apolipoprotein E	0.313
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.305
F2	coagulation factor II	0.304	Human
Nos1	nitric oxide synthase 1, neuronal	0.304
Msx1	homeobox, msh-like 1	0.302
Drd2	dopamine receptor D2	0.297
Mnda	myeloid cell nuclear differentiation antigen	0.294	Human Mouse
Fgb	fibrinogen beta chain	0.288
Gli2	GLI-Kruppel family member GLI2	0.282
Arrb1	arrestin, beta 1	0.280
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.272	Fly
Ccnb2	cyclin B2	0.270
Notch1	Notch gene homolog 1 (Drosophila)	0.270
Sox2	SRY-box containing gene 2	0.261
Chrd	chordin	0.251
Fga	fibrinogen alpha chain	0.251
Col2a1	collagen, type II, alpha 1	0.250
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.249
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.246
Ccnb1	cyclin B1	0.245
Lhx1	LIM homeobox protein 1	0.243
Notch2	Notch gene homolog 2 (Drosophila)	0.240
Ar	androgen receptor	0.240
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.227	Mouse
Msx2	homeobox, msh-like 2	0.223
Alb	albumin	0.221
Osmr	oncostatin M receptor	0.220
Vdr	vitamin D receptor	0.218
Bmp4	bone morphogenetic protein 4	0.218
Ctnnb1	catenin (cadherin associated protein), beta 1	0.218
Dlx5	distal-less homeobox 5	0.209
Ccna2	cyclin A2	0.208
Cyld	cylindromatosis (turban tumor syndrome)	0.208
Pax2	paired box gene 2	0.205	Human
Bmp7	bone morphogenetic protein 7	0.202
Ifi203	interferon activated gene 203	0.197	Mouse
Ambp	alpha 1 microglobulin/bikunin	0.196	Rat
Sox9	SRY-box containing gene 9	0.193
Fgf18	fibroblast growth factor 18	0.189
Ahsg	alpha-2-HS-glycoprotein	0.186	Mouse
Plau	plasminogen activator, urokinase	0.184
Tbx1	T-box 1	0.183
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.182
Cst3	cystatin C	0.179	Human Rat
Nog	noggin	0.177
Wnt4	wingless-related MMTV integration site 4	0.175	Mouse
C1ra	complement component 1, r subcomponent A	0.175
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.173
Smad3	MAD homolog 3 (Drosophila)	0.171
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.171
Trp73	transformation related protein 73	0.171	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.170
F12	coagulation factor XII (Hageman factor)	0.169
Lepr	leptin receptor	0.169
Cp	ceruloplasmin	0.168
Ctgf	connective tissue growth factor	0.166
Pzp	pregnancy zone protein	0.165
Anxa3	annexin A3	0.162
Bag3	BCL2-associated athanogene 3	0.161
Msln	mesothelin	0.161
Pou3f1	POU domain, class 3, transcription factor 1	0.161
Krt13	keratin 13	0.160
Gc	group specific component	0.159
Akt1	thymoma viral proto-oncogene 1	0.158
Gsn	gelsolin	0.154	Mouse
Kit	kit oncogene	0.153
Fbn1	fibrillin 1	0.150
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.150
Agxt	alanine-glyoxylate aminotransferase	0.148
Cfh	complement component factor h	0.147
Cldn4	claudin 4	0.147
Prss23	protease, serine, 23	0.145
C2	complement component 2 (within H-2S)	0.144
Rxra	retinoid X receptor alpha	0.144
Pax8	paired box gene 8	0.143
Bcl6	B-cell leukemia/lymphoma 6	0.142
Cenpj	centromere protein J	0.140
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.140
Apom	apolipoprotein M	0.139
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.139	Fly
Apoc4	apolipoprotein C-IV	0.139
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.135
Lgals3	lectin, galactose binding, soluble 3	0.133
Hpx	hemopexin	0.132
Nos2	nitric oxide synthase 2, inducible	0.131
Crct1	cysteine-rich C-terminal 1	0.131
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.129
Birc5	baculoviral IAP repeat-containing 5	0.129	Human
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.128
C9	complement component 9	0.128
Tlr4	toll-like receptor 4	0.127
Gsk3b	glycogen synthase kinase 3 beta	0.127
Il10	interleukin 10	0.127	Mouse
Fgg	fibrinogen gamma chain	0.126
Ednra	endothelin receptor type A	0.125
Bmp2	bone morphogenetic protein 2	0.124
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.124	Yeast
Gdnf	glial cell line derived neurotrophic factor	0.123
Akr1c6	aldo-keto reductase family 1, member C6	0.121
Ereg	epiregulin	0.120
Otx1	orthodenticle homolog 1 (Drosophila)	0.118
Pax9	paired box gene 9	0.118
App	amyloid beta (A4) precursor protein	0.118	Human
Cfi	complement component factor i	0.117
Socs1	suppressor of cytokine signaling 1	0.117
Rarb	retinoic acid receptor, beta	0.116
Cdk2	cyclin-dependent kinase 2	0.115
Smo	smoothened homolog (Drosophila)	0.115
Amhr2	anti-Mullerian hormone type 2 receptor	0.114
Ece1	endothelin converting enzyme 1	0.114
Lif	leukemia inhibitory factor	0.114
Sgol2	shugoshin-like 2 (S. pombe)	0.114
Itga3	integrin alpha 3	0.113
Spag5	sperm associated antigen 5	0.112
Sfn	stratifin	0.112	Human
Aebp1	AE binding protein 1	0.111
Ppl	periplakin	0.111
Pdgfb	platelet derived growth factor, B polypeptide	0.111
Kif22	kinesin family member 22	0.110
Apoa2	apolipoprotein A-II	0.110
Fos	FBJ osteosarcoma oncogene	0.109
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.108
Pmp22	peripheral myelin protein 22	0.108
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.108	Rat Fly
Ooep	oocyte expressed protein homolog (dog)	0.106
Prc1	protein regulator of cytokinesis 1	0.104
Dlx6	distal-less homeobox 6	0.104
Nnmt	nicotinamide N-methyltransferase	0.103
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.103	Human Mouse Rat
Casp12	caspase 12	0.102
Ccne2	cyclin E2	0.102	Fly
Coro1b	coronin, actin binding protein 1B	0.102
Rarg	retinoic acid receptor, gamma	0.102
Mki67	antigen identified by monoclonal antibody Ki 67	0.101
Tcra	T-cell receptor alpha chain	0.101
Kif20a	kinesin family member 20A	0.101
Prnp	prion protein	0.100
Vcp	valosin containing protein	0.100
Krtdap	keratinocyte differentiation associated protein	0.099
Sqstm1	sequestosome 1	0.098
Fosl2	fos-like antigen 2	0.098
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.098
Kng1	kininogen 1	0.097	Human
Cnr1	cannabinoid receptor 1 (brain)	0.097
Vangl2	vang-like 2 (van gogh, Drosophila)	0.097
Lamc2	laminin, gamma 2	0.096
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.096
Vhl	von Hippel-Lindau tumor suppressor	0.096
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.096
Rara	retinoic acid receptor, alpha	0.096
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.096	Mouse
A2m	alpha-2-macroglobulin	0.095	Human Rat
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.094	Yeast
Foxg1	forkhead box G1	0.094
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.094
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.094
Apof	apolipoprotein F	0.092
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.092
Ube2c	ubiquitin-conjugating enzyme E2C	0.092
Lef1	lymphoid enhancer binding factor 1	0.092	Human
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.092
Rarres2	retinoic acid receptor responder (tazarotene induced) 2	0.092
Csf1	colony stimulating factor 1 (macrophage)	0.092
Onecut1	one cut domain, family member 1	0.092
Tcfap2a	transcription factor AP-2, alpha	0.091	Mouse
Daxx	Fas death domain-associated protein	0.091
Irs1	insulin receptor substrate 1	0.091
Gdf5	growth differentiation factor 5	0.090
Ces1c	carboxylesterase 1C	0.090
Traf2	TNF receptor-associated factor 2	0.090
Bnc1	basonuclin 1	0.090
Ilk	integrin linked kinase	0.090
Egfr	epidermal growth factor receptor	0.089
Wnt5a	wingless-related MMTV integration site 5A	0.089	Mouse
Apcs	serum amyloid P-component	0.089
Dab1	disabled homolog 1 (Drosophila)	0.089
Cd151	CD151 antigen	0.088
Epha2	Eph receptor A2	0.087
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.087
Igh	immunoglobulin heavy chain complex	0.086
Pkp1	plakophilin 1	0.086
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.085	Human Mouse Rat
Ncstn	nicastrin	0.084
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.084
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.083
Dusp1	dual specificity phosphatase 1	0.083
Bcl2	B-cell leukemia/lymphoma 2	0.083	Zebrafish
Mup3	major urinary protein 3	0.082
Tmprss11e	transmembrane protease, serine 11e	0.081
Igf1r	insulin-like growth factor I receptor	0.080	Zebrafish
Tcrd	T-cell receptor delta chain	0.080
Acvr1	activin A receptor, type 1	0.080
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.080
Prrx2	paired related homeobox 2	0.079
Fxyd3	FXYD domain-containing ion transport regulator 3	0.079
F10	coagulation factor X	0.078
Lrp6	low density lipoprotein receptor-related protein 6	0.078
Hoxd13	homeobox D13	0.078
Gjb4	gap junction protein, beta 4	0.078
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.077
Gpx3	glutathione peroxidase 3	0.077
Ctnna2	catenin (cadherin associated protein), alpha 2	0.077
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.077
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.077
Egr1	early growth response 1	0.077
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.077	Mouse
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.076
Top2a	topoisomerase (DNA) II alpha	0.076
Zyx	zyxin	0.075
Apoh	apolipoprotein H	0.075
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.075
Ptch1	patched homolog 1	0.075
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.075
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.075
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.074	Mouse
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.074
Gbx2	gastrulation brain homeobox 2	0.074
Ckap2	cytoskeleton associated protein 2	0.074
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.073
C1s	complement component 1, s subcomponent	0.073
Fjx1	four jointed box 1 (Drosophila)	0.073
Aurka	aurora kinase A	0.073
Hhat	hedgehog acyltransferase	0.073
Fam46a	family with sequence similarity 46, member A	0.073
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.072
H2-Q10	histocompatibility 2, Q region locus 10	0.072
Cpz	carboxypeptidase Z	0.072
Hccs	holocytochrome c synthetase	0.071
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.071
Thbs1	thrombospondin 1	0.071	Human
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.071
Plk4	polo-like kinase 4 (Drosophila)	0.071
Sfrp1	secreted frizzled-related protein 1	0.070	Mouse
Klk6	kallikrein related-peptidase 6	0.070
Tyro3	TYRO3 protein tyrosine kinase 3	0.070
Sulf2	sulfatase 2	0.070
Hoxa3	homeobox A3	0.070
Crygd	crystallin, gamma D	0.070
Apob	apolipoprotein B	0.070
Pdpn	podoplanin	0.069
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.069
F9	coagulation factor IX	0.069
Lbp	lipopolysaccharide binding protein	0.069
Cyr61	cysteine rich protein 61	0.068
Cd40	CD40 antigen	0.068
Itgb4	integrin beta 4	0.068
Rim4	recombination induced mutation 4	0.068
Inhbb	inhibin beta-B	0.068
Ldb3	LIM domain binding 3	0.068
Tagln	transgelin	0.068
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.068
Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	0.068	Human
Fxyd1	FXYD domain-containing ion transport regulator 1	0.068
Il1a	interleukin 1 alpha	0.068
Tcf7	transcription factor 7, T-cell specific	0.068
Rbp2	retinol binding protein 2, cellular	0.067
Foxf1a	forkhead box F1a	0.067
Axin1	axin 1	0.067
Itgb3	integrin beta 3	0.067
Ngf	nerve growth factor	0.067
Kdm6a	4lysine (K)-specific demethylase 6A	0.067
Ifi204	interferon activated gene 204	0.067	Human Mouse
Dcn	decorin	0.067
Ubc	ubiquitin C	0.067
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.066
Kl	klotho	0.066
Hr	hairless	0.066
Anapc2	anaphase promoting complex subunit 2	0.066
Itm2b	integral membrane protein 2B	0.066
Ier3	immediate early response 3	0.066
Lypd3	Ly6/Plaur domain containing 3	0.066
En1	engrailed 1	0.066
Cops6	COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)	0.066
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.065
Wnt10b	wingless related MMTV integration site 10b	0.065	Mouse
Krt4	keratin 4	0.065
Igfbp6	insulin-like growth factor binding protein 6	0.065
Rnf41	ring finger protein 41	0.065
Gata3	GATA binding protein 3	0.065
Dll1	delta-like 1 (Drosophila)	0.064
Cenpe	centromere protein E	0.064
Pou5f1	POU domain, class 5, transcription factor 1	0.064
Brca1	breast cancer 1	0.064
AI607873	expressed sequence AI607873	0.064	Mouse
Apoc2	apolipoprotein C-II	0.063
Krt6a	keratin 6A	0.063
Foxm1	forkhead box M1	0.063
Il6st	interleukin 6 signal transducer	0.063
Cd80	CD80 antigen	0.063
Csnk1g2	casein kinase 1, gamma 2	0.063
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.063
Sh3pxd2a	SH3 and PX domains 2A	0.063
Stfa3	stefin A3	0.063	Human Mouse
Ptf1a	pancreas specific transcription factor, 1a	0.062
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.062	Fly
Inhba	inhibin beta-A	0.062
Pyhin1	pyrin and HIN domain family, member 1	0.062	Mouse
Il1r1	interleukin 1 receptor, type I	0.061
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.061
Aimp1	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	0.061
Sim2	single-minded homolog 2 (Drosophila)	0.061
Diablo	diablo homolog (Drosophila)	0.061
Sgol1	shugoshin-like 1 (S. pombe)	0.060
Crb2	crumbs homolog 2 (Drosophila)	0.060	Human
T	brachyury	0.060
Foxn1	forkhead box N1	0.060
Ube3a	ubiquitin protein ligase E3A	0.060
Thbd	thrombomodulin	0.060
Osbpl9	oxysterol binding protein-like 9	0.060
Ccnf	cyclin F	0.060
Pbxip1	pre-B-cell leukemia transcription factor interacting protein 1	0.060
Brca2	breast cancer 2	0.060
Ikbkb	inhibitor of kappaB kinase beta	0.060
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.059
Foxc2	forkhead box C2	0.059
Plaur	plasminogen activator, urokinase receptor	0.059
Depdc1a	DEP domain containing 1a	0.059
Mall	mal, T-cell differentiation protein-like	0.059
Sp1	trans-acting transcription factor 1	0.059
Nradd	neurotrophin receptor associated death domain	0.059
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.058
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.058
Fgf10	fibroblast growth factor 10	0.058
Agtr1a	angiotensin II receptor, type 1a	0.058
Mbl2	mannose-binding lectin (protein C) 2	0.058
Masp1	mannan-binding lectin serine peptidase 1	0.058
Gpr87	G protein-coupled receptor 87	0.058
Spry4	sprouty homolog 4 (Drosophila)	0.058
Hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.057
Hoxb9	homeobox B9	0.057
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.057	Mouse
Atp11c	ATPase, class VI, type 11C	0.057
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.057
Dlg1	discs, large homolog 1 (Drosophila)	0.056
Rnase4	ribonuclease, RNase A family 4	0.056
Smarcb1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.056
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.056	Mouse
Cdx2	caudal type homeobox 2	0.056
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.055
BC100530	cDNA sequence BC100530	0.055	Human Mouse
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.055
Cdca8	cell division cycle associated 8	0.055
Tgfb2	transforming growth factor, beta 2	0.055
Npn2	neoplastic progression 2	0.055
Clic3	chloride intracellular channel 3	0.055
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.055
Fhdc1	FH2 domain containing 1	0.055
Trim30a	tripartite motif-containing 30A	0.054
Apoc1	apolipoprotein C-I	0.054
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.054
Fcgrt	Fc receptor, IgG, alpha chain transporter	0.054
Lipc	lipase, hepatic	0.054
Runx1	runt related transcription factor 1	0.054
Fgl2	fibrinogen-like protein 2	0.054
Mgp	matrix Gla protein	0.054
Isl1	ISL1 transcription factor, LIM/homeodomain	0.054
Fzd4	frizzled homolog 4 (Drosophila)	0.053
Ivl	involucrin	0.053
Tnni2	troponin I, skeletal, fast 2	0.053
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.053
Irf6	interferon regulatory factor 6	0.053
Scube1	signal peptide, CUB domain, EGF-like 1	0.053
Lin9	lin-9 homolog (C. elegans)	0.052
Lcn2	lipocalin 2	0.052
Hp	haptoglobin	0.052
Prrx1	paired related homeobox 1	0.052
Pcm1	pericentriolar material 1	0.052
Huwe1	HECT, UBA and WWE domain containing 1	0.052
C1rb	complement component 1, r subcomponent B	0.052
Prkcb	protein kinase C, beta	0.052
Hc	hemolytic complement	0.052	Mouse
Hal	histidine ammonia lyase	0.051
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.051
Tgfbi	transforming growth factor, beta induced	0.051
Fgfr3	fibroblast growth factor receptor 3	0.051
Orm2	orosomucoid 2	0.051
Dnase1l2	deoxyribonuclease 1-like 2	0.051
Prlr	prolactin receptor	0.051
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.050
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.050
Cfb	complement factor B	0.050
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.050
Runx2	runt related transcription factor 2	0.050
Apc	adenomatosis polyposis coli	0.050	Human
Tbx3	T-box 3	0.049
Vim	vimentin	0.049
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.049
Flnc	filamin C, gamma	0.049
Igfbp1	insulin-like growth factor binding protein 1	0.049
Traf6	TNF receptor-associated factor 6	0.049
Ctsd	cathepsin D	0.049
Plaa	phospholipase A2, activating protein	0.049
Kpna1	karyopherin (importin) alpha 1	0.049
Dmgdh	dimethylglycine dehydrogenase precursor	0.049
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.048
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.048
Pxn	paxillin	0.048
Procr	protein C receptor, endothelial	0.048
Asprv1	aspartic peptidase, retroviral-like 1	0.048
Creb1	cAMP responsive element binding protein 1	0.048
Nod2	nucleotide-binding oligomerization domain containing 2	0.048
Igf2r	insulin-like growth factor 2 receptor	0.048
Tcf3	transcription factor 3	0.048
Efnb2	ephrin B2	0.048
Ret	ret proto-oncogene	0.048
Jak2	Janus kinase 2	0.048
Crabp2	cellular retinoic acid binding protein II	0.048
Nupr1	nuclear protein 1	0.048
Aicda	activation-induced cytidine deaminase	0.047
Cpn1	carboxypeptidase N, polypeptide 1	0.047
Uox	urate oxidase	0.047
Slc46a2	solute carrier family 46, member 2	0.047
Pknox1	Pbx/knotted 1 homeobox	0.047
Tacstd2	tumor-associated calcium signal transducer 2	0.047
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.047
Sfrp5	secreted frizzled-related sequence protein 5	0.047	Mouse
Racgap1	Rac GTPase-activating protein 1	0.047
Mug1	murinoglobulin 1	0.047	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.047
F2r	coagulation factor II (thrombin) receptor	0.047
Dmkn	dermokine	0.047
Acta1	actin, alpha 1, skeletal muscle	0.046
Serpinb6b	serine (or cysteine) peptidase inhibitor, clade B, member 6b	0.046	Human Mouse
Sox1	SRY-box containing gene 1	0.046
Ccr1	chemokine (C-C motif) receptor 1	0.046
H2afx	H2A histone family, member X	0.046
Cxcl2	chemokine (C-X-C motif) ligand 2	0.046
Plk1	polo-like kinase 1 (Drosophila)	0.046	Human
Gsg2	germ cell-specific gene 2	0.046
Pdx1	pancreatic and duodenal homeobox 1	0.046
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.046
Hist2h4	histone cluster 2, H4	0.046
Lgals2	lectin, galactose-binding, soluble 2	0.046
Foxa1	forkhead box A1	0.045
Dhh	desert hedgehog	0.045	Mouse Fly
Sprr1a	small proline-rich protein 1A	0.045
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.045
Capn1	calpain 1	0.045
Gpr56	G protein-coupled receptor 56	0.045
Nf1	neurofibromatosis 1	0.045
Shkbp1	Sh3kbp1 binding protein 1	0.045
Anxa1	annexin A1	0.045
Chmp2a	chromatin modifying protein 2A	0.045
Hoxd11	homeobox D11	0.045
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.045
Mug2	murinoglobulin 2	0.044
Pbx1	pre B-cell leukemia transcription factor 1	0.044
Cldn14	claudin 14	0.044
Btc	betacellulin, epidermal growth factor family member	0.044
Timp2	tissue inhibitor of metalloproteinase 2	0.044
Emp2	epithelial membrane protein 2	0.044
Porcn	porcupine homolog (Drosophila)	0.044
Cbx1	chromobox homolog 1 (Drosophila HP1 beta)	0.044
Foxa2	forkhead box A2	0.043
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.043
Vars	valyl-tRNA synthetase	0.043
Tgm2	transglutaminase 2, C polypeptide	0.043
Hbegf	heparin-binding EGF-like growth factor	0.043
Saa3	serum amyloid A 3	0.043
Qk	quaking	0.043
Hist2h3c2-ps	histone cluster 2, H3c2, pseudogene	0.043
Hipk1	homeodomain interacting protein kinase 1	0.043
Fuca1	fucosidase, alpha-L- 1, tissue	0.043
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.043
Grn	granulin	0.043
Nrp1	neuropilin 1	0.043
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.043
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.043	Human Mouse Rat
Lrp5	low density lipoprotein receptor-related protein 5	0.043
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.043	Mouse
Atf3	activating transcription factor 3	0.043
Serpinb3b	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B	0.043
Pah	phenylalanine hydroxylase	0.043
Cdh3	cadherin 3	0.043
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.043
Tex264	testis expressed gene 264	0.043
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.043
Sfrp4	secreted frizzled-related protein 4	0.043
Hba-a2	hemoglobin alpha, adult chain 2	0.043
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.042
Lig4	ligase IV, DNA, ATP-dependent	0.042
Sardh	sarcosine dehydrogenase	0.042
Krt5	keratin 5	0.042
Dbf4	DBF4 homolog (S. cerevisiae)	0.042
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.042
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.042
Fgf15	fibroblast growth factor 15	0.042
Glrx3	glutaredoxin 3	0.042
Ephx1	epoxide hydrolase 1, microsomal	0.042
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.042
Ecm1	extracellular matrix protein 1	0.042	Human
Nlrp5	NLR family, pyrin domain containing 5	0.042
Anxa2	annexin A2	0.042
Hoxc8	homeobox C8	0.042
Gm11397	predicted gene 11397	0.042
Cd81	CD81 antigen	0.042
Tnnt3	troponin T3, skeletal, fast	0.042
F13b	coagulation factor XIII, beta subunit	0.042
Sox11	SRY-box containing gene 11	0.041
Actn3	actinin alpha 3	0.041
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.041
Purb	purine rich element binding protein B	0.041
Sprr1b	small proline-rich protein 1B	0.041
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.041
Saa2	serum amyloid A 2	0.041
Cenpn	centromere protein N	0.041
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.041
Orm1	orosomucoid 1	0.041
Fbxw7	F-box and WD-40 domain protein 7	0.041
Vdac3	voltage-dependent anion channel 3	0.041
Rnf2	ring finger protein 2	0.041
Cep55	centrosomal protein 55	0.041
Vcam1	vascular cell adhesion molecule 1	0.040
Smc4	structural maintenance of chromosomes 4	0.040
Fam83h	family with sequence similarity 83, member H	0.040
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.040
Il1f9	interleukin 1 family, member 9	0.040
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.040
Cops5	COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)	0.040	Fly
Fshr	follicle stimulating hormone receptor	0.040
Gm10393	predicted gene 10393	0.040
Atoh7	atonal homolog 7 (Drosophila)	0.040
Dsg1a	desmoglein 1 alpha	0.040
Errfi1	ERBB receptor feedback inhibitor 1	0.040
Krt19	keratin 19	0.040
Sprr2a2	small proline-rich protein 2A2	0.040
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.040
Braf	Braf transforming gene	0.040
Fbxo5	F-box protein 5	0.040	Human Fly
Nppb	natriuretic peptide type B	0.040
Serpinb6c	serine (or cysteine) peptidase inhibitor, clade B, member 6c	0.039	Human Mouse
Ufc1	ubiquitin-fold modifier conjugating enzyme 1	0.039
Efna4	ephrin A4	0.039
Arx	aristaless related homeobox	0.039
Klf2	Kruppel-like factor 2 (lung)	0.039
Rag2	recombination activating gene 2	0.039
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.039
Ncapg	non-SMC condensin I complex, subunit G	0.039
Fabp1	fatty acid binding protein 1, liver	0.039	Human
Tpbg	trophoblast glycoprotein	0.039
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.039
G6pc	glucose-6-phosphatase, catalytic	0.039
Rhod	ras homolog gene family, member D	0.039
Ang2	angiogenin, ribonuclease A family, member 2	0.039
Rgn	regucalcin	0.039
Bdnf	brain derived neurotrophic factor	0.039
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.039
C8a	complement component 8, alpha polypeptide	0.039
Epas1	endothelial PAS domain protein 1	0.039
Crybb2	crystallin, beta B2	0.039
Ly6a	lymphocyte antigen 6 complex, locus A	0.039
Lgals7	lectin, galactose binding, soluble 7	0.038
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.038
Ccdc80	coiled-coil domain containing 80	0.038
Trf	transferrin	0.038
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.038
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.038
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.038
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.038
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.038
Cd44	CD44 antigen	0.038	Human
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.038
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.038
Grb10	growth factor receptor bound protein 10	0.038
Skp1a	S-phase kinase-associated protein 1A	0.038
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.038
Smad7	MAD homolog 7 (Drosophila)	0.038
Myl9	myosin, light polypeptide 9, regulatory	0.038
Klf6	Kruppel-like factor 6	0.038
Areg	amphiregulin	0.038
Samd10	sterile alpha motif domain containing 10	0.038
Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.038
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.038
Foxq1	forkhead box Q1	0.038
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.038
Gvin1	GTPase, very large interferon inducible 1	0.038
Hist1h2bm	histone cluster 1, H2bm	0.038
Saa4	serum amyloid A 4	0.038
Hes1	hairy and enhancer of split 1 (Drosophila)	0.038
Il22	interleukin 22	0.038	Mouse
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.037
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.037
Ptgs1	prostaglandin-endoperoxide synthase 1	0.037
Tgfa	transforming growth factor alpha	0.037
Ctsj	cathepsin J	0.037
Nlrp3	NLR family, pyrin domain containing 3	0.037
Fuz	fuzzy homolog (Drosophila)	0.037
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.037
Csk	c-src tyrosine kinase	0.037
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.037
Cks2	CDC28 protein kinase regulatory subunit 2	0.037
Arg1	arginase, liver	0.037
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.037
Acpp	acid phosphatase, prostate	0.037
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.037
Gjb5	gap junction protein, beta 5	0.037
Bcl2l10	Bcl2-like 10	0.037
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.037
S100a14	S100 calcium binding protein A14	0.037
Lect2	leukocyte cell-derived chemotaxin 2	0.037
Dsg4	desmoglein 4	0.037
Vtn	vitronectin	0.036
Gm4788	predicted gene 4788	0.036
Col4a3	collagen, type IV, alpha 3	0.036
Hoxa13	homeobox A13	0.036
Fosb	FBJ osteosarcoma oncogene B	0.036
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.036
Anxa8	annexin A8	0.036	Human
Lmx1a	LIM homeobox transcription factor 1 alpha	0.036
Sult2b1	sulfotransferase family, cytosolic, 2B, member 1	0.036
Ifi30	interferon gamma inducible protein 30	0.036
Lce1a1	late cornified envelope 1A1	0.036
Apoa5	apolipoprotein A-V	0.036
Btg2	B-cell translocation gene 2, anti-proliferative	0.036
C4b	complement component 4B (Childo blood group)	0.036	Mouse
Dctn1	dynactin 1	0.036
Rhoc	ras homolog gene family, member C	0.036
Prss22	protease, serine, 22	0.036
Foxf2	forkhead box F2	0.036
Nt5e	5' nucleotidase, ecto	0.036
Ncapg2	non-SMC condensin II complex, subunit G2	0.036
Alas2	aminolevulinic acid synthase 2, erythroid	0.036
Dnase1l1	deoxyribonuclease 1-like 1	0.036
Cldn1	claudin 1	0.035
Pkp3	plakophilin 3	0.035
Rnf7	ring finger protein 7	0.035
E2f1	E2F transcription factor 1	0.035
Ikbkg	inhibitor of kappaB kinase gamma	0.035
Il11	interleukin 11	0.035
Plat	plasminogen activator, tissue	0.035	Human
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.035
Des	desmin	0.035
Gsdma3	gasdermin A3	0.035
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.035
Pam	peptidylglycine alpha-amidating monooxygenase	0.035
Steap4	STEAP family member 4	0.035
F3	coagulation factor III	0.035
Snap25	synaptosomal-associated protein 25	0.035
Aff4	AF4/FMR2 family, member 4	0.035
Car12	carbonic anyhydrase 12	0.035
Hist1h2ao	histone cluster 1, H2ao	0.034
Gba	glucosidase, beta, acid	0.034
Hist1h2aa	histone cluster 1, H2aa	0.034
Gja3	gap junction protein, alpha 3	0.034
Fbxo6	F-box protein 6	0.034
Cdh1	cadherin 1	0.034
Drd1a	dopamine receptor D1A	0.034
Il6	interleukin 6	0.034
Hdac3	histone deacetylase 3	0.034
Set	SET nuclear oncogene	0.034
Bst1	bone marrow stromal cell antigen 1	0.034
S100a10	S100 calcium binding protein A10 (calpactin)	0.034
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.034
Nrk	Nik related kinase	0.034
Slfn8	schlafen 8	0.034
Egr2	early growth response 2	0.034
Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	0.034
Usp15	ubiquitin specific peptidase 15	0.034
Ces1g	carboxylesterase 1G	0.034
Fstl3	follistatin-like 3	0.034
Cbl	Casitas B-lineage lymphoma	0.034
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.033
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.033
Klf5	Kruppel-like factor 5	0.033
Tdo2	tryptophan 2,3-dioxygenase	0.033
Krt75	keratin 75	0.033
Gm13290	predicted gene 13290	0.033
Scrg1	scrapie responsive gene 1	0.033
Fst	follistatin	0.033
Fbxo38	F-box protein 38	0.033
Hnf4a	hepatic nuclear factor 4, alpha	0.033
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.033
Cebpz	CCAAT/enhancer binding protein zeta	0.033
Ccl7	chemokine (C-C motif) ligand 7	0.033
Met	met proto-oncogene	0.033
Scrib	scribbled homolog (Drosophila)	0.033
Rras	Harvey rat sarcoma oncogene, subgroup R	0.033
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.033
Trim30d	tripartite motif-containing 30D	0.033
Duoxa1	dual oxidase maturation factor 1	0.033
Melk	maternal embryonic leucine zipper kinase	0.033
Mis18bp1	MIS18 binding protein 1	0.033
Axin2	axin2	0.033
Plxna1	plexin A1	0.033
Hdac4	histone deacetylase 4	0.033
Aqp9	aquaporin 9	0.033
Srgn	serglycin	0.033
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.033
Fgfbp1	fibroblast growth factor binding protein 1	0.033
Krtap4-16	keratin associated protein 4-16	0.033
Trim59	tripartite motif-containing 59	0.033
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.032
Ccl9	chemokine (C-C motif) ligand 9	0.032
Tnf	tumor necrosis factor	0.032
Wwox	WW domain-containing oxidoreductase	0.032
Gckr	glucokinase regulatory protein	0.032
Prph2	peripherin 2	0.032
Wrn	Werner syndrome homolog (human)	0.032
Col17a1	collagen, type XVII, alpha 1	0.032
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.032
Ep300	E1A binding protein p300	0.032
Cd28	CD28 antigen	0.032
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.032
Pax1	paired box gene 1	0.032
Gtse1	G two S phase expressed protein 1	0.032