IMP: Integrative Multi-species Prediction

Mus musculus

77 genes annotated in mouse

Multi-species View

regulation of extrinsic apoptotic signaling pathway

GO:2001236

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of extrinsic apoptotic signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of extrinsic apoptotic signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Col1a1	collagen, type I, alpha 1	1.000	Mouse
Trp53	transformation related protein 53	1.000
Tnf	tumor necrosis factor	0.998
Pten	phosphatase and tensin homolog	0.998
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.993	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.993
Tgfb1	transforming growth factor, beta 1	0.992	Mouse
Cd19	CD19 antigen	0.963
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.961
Lyz2	lysozyme 2	0.946
Csf1	colony stimulating factor 1 (macrophage)	0.943
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.922
Runx1	runt related transcription factor 1	0.917	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.916
Cd44	CD44 antigen	0.904
Bax	BCL2-associated X protein	0.895
Ptgs2	prostaglandin-endoperoxide synthase 2	0.895
Tgfbr2	transforming growth factor, beta receptor II	0.882	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.882	Human Mouse
Casp8	caspase 8	0.882
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.871
Ikzf1	IKAROS family zinc finger 1	0.871
Notch2	Notch gene homolog 2 (Drosophila)	0.861
Esr1	estrogen receptor 1 (alpha)	0.856
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.844	Mouse
Fbn1	fibrillin 1	0.826
Mmp9	matrix metallopeptidase 9	0.818
Tnip1	TNFAIP3 interacting protein 1	0.808
Il2rg	interleukin 2 receptor, gamma chain	0.774
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.768	Mouse
Egfr	epidermal growth factor receptor	0.747
Foxp3	forkhead box P3	0.737
Igh	immunoglobulin heavy chain complex	0.734
Sharpin	SHANK-associated RH domain interacting protein	0.728	Mouse
Nos1	nitric oxide synthase 1, neuronal	0.715
Apc	adenomatosis polyposis coli	0.710
Notch1	Notch gene homolog 1 (Drosophila)	0.709
Il10	interleukin 10	0.707	Mouse
Yap1	yes-associated protein 1	0.704
Fas	Fas (TNF receptor superfamily member 6)	0.699
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.683
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.675	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.675
Nos2	nitric oxide synthase 2, inducible	0.665
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.664
Fst	follistatin	0.655
Ccr2	chemokine (C-C motif) receptor 2	0.643	Mouse
Itch	itchy, E3 ubiquitin protein ligase	0.634
Nf1	neurofibromatosis 1	0.626
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.611
Il4ra	interleukin 4 receptor, alpha	0.606
Col5a2	collagen, type V, alpha 2	0.603	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.596	Mouse
Cbl	Casitas B-lineage lymphoma	0.594
Pdcd1	programmed cell death 1	0.591
Hr	hairless	0.584
App	amyloid beta (A4) precursor protein	0.581
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.547
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.544
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.544	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.540	Mouse
Col3a1	collagen, type III, alpha 1	0.528	Mouse
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.527
Cd40	CD40 antigen	0.511
Socs1	suppressor of cytokine signaling 1	0.509
Efnb2	ephrin B2	0.509
Ifng	interferon gamma	0.503
Skil	SKI-like	0.479
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.478
Thbs1	thrombospondin 1	0.477	Human
Adam17	a disintegrin and metallopeptidase domain 17	0.476
Mdm2	transformed mouse 3T3 cell double minute 2	0.476
Lepr	leptin receptor	0.475
Fshr	follicle stimulating hormone receptor	0.474
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.455
Mcl1	myeloid cell leukemia sequence 1	0.449	Human Mouse
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.437
Smad3	MAD homolog 3 (Drosophila)	0.418
Casp3	caspase 3	0.418	Mouse
Rara	retinoic acid receptor, alpha	0.412
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.407
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.406
Ret	ret proto-oncogene	0.394	Human
Runx2	runt related transcription factor 2	0.390	Mouse
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.390
Fyn	Fyn proto-oncogene	0.388	Rat
Tgfb2	transforming growth factor, beta 2	0.386
Rbl1	retinoblastoma-like 1 (p107)	0.381
Inpp5d	inositol polyphosphate-5-phosphatase D	0.373
Fgfr1	fibroblast growth factor receptor 1	0.355
Vegfa	vascular endothelial growth factor A	0.352
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.345
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.344	Mouse
Snai1	snail homolog 1 (Drosophila)	0.336	Mouse
Ltb	lymphotoxin B	0.335
Wnt5a	wingless-related MMTV integration site 5A	0.330
Cxcl12	chemokine (C-X-C motif) ligand 12	0.330
Psen1	presenilin 1	0.328	Mouse
Bcl3	B-cell leukemia/lymphoma 3	0.328
Xiap	X-linked inhibitor of apoptosis	0.324
Lmnb1	lamin B1	0.322	Mouse
Lta	lymphotoxin A	0.318
Wrn	Werner syndrome homolog (human)	0.318
Rxra	retinoid X receptor alpha	0.315
Ahr	aryl-hydrocarbon receptor	0.314
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.312
Pthlh	parathyroid hormone-like peptide	0.311
Irf1	interferon regulatory factor 1	0.310
Ptk2	PTK2 protein tyrosine kinase 2	0.308
Foxc1	forkhead box C1	0.304
Ncoa3	nuclear receptor coactivator 3	0.302
Pax3	paired box gene 3	0.292
Il18rap	interleukin 18 receptor accessory protein	0.292
Stat3	signal transducer and activator of transcription 3	0.291
Tlr4	toll-like receptor 4	0.289
Braf	Braf transforming gene	0.280	Mouse
Itgb3	integrin beta 3	0.274
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.274
Sfrp2	secreted frizzled-related protein 2	0.273
Gclm	glutamate-cysteine ligase, modifier subunit	0.272
Ciita	class II transactivator	0.272
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.271
Shc1	src homology 2 domain-containing transforming protein C1	0.271
Itgal	integrin alpha L	0.269
Fgd1	FYVE, RhoGEF and PH domain containing 1	0.267
Il1b	interleukin 1 beta	0.263	Human
Selp	selectin, platelet	0.262
Ikbkg	inhibitor of kappaB kinase gamma	0.260
Ghr	growth hormone receptor	0.259
Mdm4	transformed mouse 3T3 cell double minute 4	0.254
Bcl6	B-cell leukemia/lymphoma 6	0.253
Ccl2	chemokine (C-C motif) ligand 2	0.253
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.253
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.252
Casp1	caspase 1	0.249	Mouse
Col6a2	collagen, type VI, alpha 2	0.242
Smad2	MAD homolog 2 (Drosophila)	0.239
Inhba	inhibin beta-A	0.239	Human
Ctnna1	catenin (cadherin associated protein), alpha 1	0.238
Prrx2	paired related homeobox 2	0.236
Atr	ataxia telangiectasia and Rad3 related	0.232
Sparc	secreted acidic cysteine rich glycoprotein	0.226
Gclc	glutamate-cysteine ligase, catalytic subunit	0.226
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.221
Sufu	suppressor of fused homolog (Drosophila)	0.217
Rarg	retinoic acid receptor, gamma	0.217
Phox2a	paired-like homeobox 2a	0.216
Msx2	homeobox, msh-like 2	0.214
Wisp2	WNT1 inducible signaling pathway protein 2	0.212
Gja1	gap junction protein, alpha 1	0.206
Postn	periostin, osteoblast specific factor	0.204
Insr	insulin receptor	0.203
Ddr2	discoidin domain receptor family, member 2	0.201
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.200
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.199
Traf6	TNF receptor-associated factor 6	0.198
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.197	Human
Kitl	kit ligand	0.197
Col6a1	collagen, type VI, alpha 1	0.196
Sox9	SRY-box containing gene 9	0.196
Batf	basic leucine zipper transcription factor, ATF-like	0.195
Plxnd1	plexin D1	0.193
Hif1a	hypoxia inducible factor 1, alpha subunit	0.188
Meox2	mesenchyme homeobox 2	0.188
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.184
Bmp4	bone morphogenetic protein 4	0.180
Cdk4	cyclin-dependent kinase 4	0.179
Itga4	integrin alpha 4	0.178
Bmp1	bone morphogenetic protein 1	0.177
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.176	Human
Capn6	calpain 6	0.174
Pml	promyelocytic leukemia	0.173	Human
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.173
Il1a	interleukin 1 alpha	0.172
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.172
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.171
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.170
Src	Rous sarcoma oncogene	0.169	Human
Col11a1	collagen, type XI, alpha 1	0.169	Mouse
Lum	lumican	0.167
Prrx1	paired related homeobox 1	0.167
Creb1	cAMP responsive element binding protein 1	0.163
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.162
Rasal3	RAS protein activator like 3	0.161
Icos	inducible T-cell co-stimulator	0.161
Amhr2	anti-Mullerian hormone type 2 receptor	0.161	Mouse
Sh2d2a	SH2 domain protein 2A	0.160
Pcolce	procollagen C-endopeptidase enhancer protein	0.159
Gpr132	G protein-coupled receptor 132	0.158
Acvr1	activin A receptor, type 1	0.158	Human Mouse
Dll1	delta-like 1 (Drosophila)	0.158
Mkl2	MKL/myocardin-like 2	0.157
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.155
Apoe	apolipoprotein E	0.154
Vhl	von Hippel-Lindau tumor suppressor	0.153
Nlrp3	NLR family, pyrin domain containing 3	0.151
Eng	endoglin	0.151
Birc3	baculoviral IAP repeat-containing 3	0.150
Sgpl1	sphingosine phosphate lyase 1	0.148
Lif	leukemia inhibitory factor	0.148
Ilk	integrin linked kinase	0.148
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.148
Il10ra	interleukin 10 receptor, alpha	0.147
Ccnd1	cyclin D1	0.146
Tcra	T-cell receptor alpha chain	0.145
Fgf7	fibroblast growth factor 7	0.145	Mouse
Cxcl13	chemokine (C-X-C motif) ligand 13	0.144
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.144
Vdr	vitamin D receptor	0.144
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.143
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.140	Human
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.138
Pvr	poliovirus receptor	0.137
Pgr	progesterone receptor	0.137
Il22	interleukin 22	0.137	Mouse
Il2rb	interleukin 2 receptor, beta chain	0.136
Mapk3	mitogen-activated protein kinase 3	0.136
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.136
Myo1f	myosin IF	0.134
Foxn1	forkhead box N1	0.134
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.134
Ctnnd1	catenin (cadherin associated protein), delta 1	0.133
Elk4	ELK4, member of ETS oncogene family	0.133
Sfrp1	secreted frizzled-related protein 1	0.133
Cbfb	core binding factor beta	0.132
Col4a1	collagen, type IV, alpha 1	0.132
Nod2	nucleotide-binding oligomerization domain containing 2	0.130
Mapk8	mitogen-activated protein kinase 8	0.130
Lmna	lamin A	0.129
Fgfr3	fibroblast growth factor receptor 3	0.128	Mouse
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.128
Flt4	FMS-like tyrosine kinase 4	0.128
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.127
Fadd	Fas (TNFRSF6)-associated via death domain	0.127
Lep	leptin	0.126
Smn1	survival motor neuron 1	0.126
Kdr	kinase insert domain protein receptor	0.126
Il6st	interleukin 6 signal transducer	0.125
Il18	interleukin 18	0.124
Il27ra	interleukin 27 receptor, alpha	0.124
Thra	thyroid hormone receptor alpha	0.124
Hs1bp3	HCLS1 binding protein 3	0.123
Tbx15	T-box 15	0.122
Ccr5	chemokine (C-C motif) receptor 5	0.121	Mouse
Bdnf	brain derived neurotrophic factor	0.120
Id2	inhibitor of DNA binding 2	0.119
Vcl	vinculin	0.118	Mouse
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.118
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.118
Snai2	snail homolog 2 (Drosophila)	0.118
Col2a1	collagen, type II, alpha 1	0.117
Lox	lysyl oxidase	0.116
Hapln1	hyaluronan and proteoglycan link protein 1	0.115
Cenpj	centromere protein J	0.115
Col4a5	collagen, type IV, alpha 5	0.112
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.112
Cav1	caveolin 1, caveolae protein	0.111	Human
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.111
Ccl3	chemokine (C-C motif) ligand 3	0.111
Myc	myelocytomatosis oncogene	0.111
Il1r1	interleukin 1 receptor, type I	0.110
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.109
Prf1	perforin 1 (pore forming protein)	0.109
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.109
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.108
Nrk	Nik related kinase	0.107
Irf4	interferon regulatory factor 4	0.107
Tlr2	toll-like receptor 2	0.106
Sfpi1	SFFV proviral integration 1	0.106
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.105
Trp63	transformation related protein 63	0.105
Acan	aggrecan	0.105
Bmp5	bone morphogenetic protein 5	0.104
Tgfbr1	transforming growth factor, beta receptor I	0.103	Human Mouse
Cxcr5	chemokine (C-X-C motif) receptor 5	0.103	Mouse
Wwtr1	WW domain containing transcription regulator 1	0.101	Mouse
Cst3	cystatin C	0.101
Fstl1	follistatin-like 1	0.101
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.101
Cdh1	cadherin 1	0.101
Fgfr2	fibroblast growth factor receptor 2	0.100	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.100
Drd2	dopamine receptor D2	0.100
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.100
Gli3	GLI-Kruppel family member GLI3	0.100
Skp1a	S-phase kinase-associated protein 1A	0.100
Efs	embryonal Fyn-associated substrate	0.100
Lck	lymphocyte protein tyrosine kinase	0.100
Itgb2	integrin beta 2	0.099
Pxn	paxillin	0.099
Gbp5	guanylate binding protein 5	0.099
Ctsl	cathepsin L	0.098
Numb	numb gene homolog (Drosophila)	0.098
Dsg4	desmoglein 4	0.097
Itgb5	integrin beta 5	0.097
Elf4	E74-like factor 4 (ets domain transcription factor)	0.097
Cyld	cylindromatosis (turban tumor syndrome)	0.096	Human
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.095
Eya1	eyes absent 1 homolog (Drosophila)	0.095
Myb	myeloblastosis oncogene	0.095
Hoxd11	homeobox D11	0.094
Nf2	neurofibromatosis 2	0.094
Col8a1	collagen, type VIII, alpha 1	0.094
Tnc	tenascin C	0.094
Col4a2	collagen, type IV, alpha 2	0.093
Plcg1	phospholipase C, gamma 1	0.092
F2	coagulation factor II	0.092
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.091
Rarb	retinoic acid receptor, beta	0.091
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.091
Fzd1	frizzled homolog 1 (Drosophila)	0.091
Fam20c	family with sequence similarity 20, member C	0.091
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.091
Spnb2	spectrin beta 2	0.091
C3ar1	complement component 3a receptor 1	0.090
Angptl2	angiopoietin-like 2	0.090
Lama4	laminin, alpha 4	0.090
Il2	interleukin 2	0.090
Coro1b	coronin, actin binding protein 1B	0.090
Cdh5	cadherin 5	0.089
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.089
Atm	ataxia telangiectasia mutated homolog (human)	0.089
Cnr1	cannabinoid receptor 1 (brain)	0.088
Tmpo	thymopoietin	0.088
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.088
Cdc42se1	CDC42 small effector 1	0.087
Daxx	Fas death domain-associated protein	0.087
Ctsk	cathepsin K	0.087
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.087
Ar	androgen receptor	0.087	Human
Vav2	vav 2 oncogene	0.086
Bcar1	breast cancer anti-estrogen resistance 1	0.086
Cd96	CD96 antigen	0.086
Tbx21	T-box 21	0.086
Ikbkb	inhibitor of kappaB kinase beta	0.086
Ifnar1	interferon (alpha and beta) receptor 1	0.086
Gsk3b	glycogen synthase kinase 3 beta	0.086
Card11	caspase recruitment domain family, member 11	0.085
Stk4	serine/threonine kinase 4	0.085
Angpt4	angiopoietin 4	0.085
Tgfa	transforming growth factor alpha	0.084
Wipf1	WAS/WASL interacting protein family, member 1	0.084
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.083
Shc3	src homology 2 domain-containing transforming protein C3	0.083
Dok1	docking protein 1	0.083
Jak2	Janus kinase 2	0.083	Mouse
Ptx3	pentraxin related gene	0.082
S1pr4	sphingosine-1-phosphate receptor 4	0.082
Tox	thymocyte selection-associated high mobility group box	0.082
Cd6	CD6 antigen	0.081
Dhh	desert hedgehog	0.081
Met	met proto-oncogene	0.081
Pax8	paired box gene 8	0.079
Ptgir	prostaglandin I receptor (IP)	0.079
Rnf31	ring finger protein 31	0.079
Has2	hyaluronan synthase 2	0.078
Hbegf	heparin-binding EGF-like growth factor	0.078
Ptgfrn	prostaglandin F2 receptor negative regulator	0.078
Ccr6	chemokine (C-C motif) receptor 6	0.078	Mouse
Npr3	natriuretic peptide receptor 3	0.078
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.078
Unc93b1	unc-93 homolog B1 (C. elegans)	0.077
Plaur	plasminogen activator, urokinase receptor	0.077
Twist1	twist homolog 1 (Drosophila)	0.077
Cdh11	cadherin 11	0.077
Rbl2	retinoblastoma-like 2	0.076
Anapc2	anaphase promoting complex subunit 2	0.076
Cybb	cytochrome b-245, beta polypeptide	0.075
Fbln2	fibulin 2	0.075
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.075
Mfn2	mitofusin 2	0.075
Hoxa1	homeobox A1	0.075
Fli1	Friend leukemia integration 1	0.075
Irs1	insulin receptor substrate 1	0.075
Btk	Bruton agammaglobulinemia tyrosine kinase	0.074
Creb3l1	cAMP responsive element binding protein 3-like 1	0.074
Bak1	BCL2-antagonist/killer 1	0.074	Mouse
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.074
Uba7	ubiquitin-like modifier activating enzyme 7	0.074
Id1	inhibitor of DNA binding 1	0.074
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.073
Cd81	CD81 antigen	0.073
Epor	erythropoietin receptor	0.073
Smad4	MAD homolog 4 (Drosophila)	0.073
Osmr	oncostatin M receptor	0.072
Rac1	RAS-related C3 botulinum substrate 1	0.072
Gsdma3	gasdermin A3	0.072
Pikfyve	phosphoinositide kinase, FYVE finger containing	0.071
Ccdc80	coiled-coil domain containing 80	0.071
Il4	interleukin 4	0.071
Thbs3	thrombospondin 3	0.070
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.070
Smad5	MAD homolog 5 (Drosophila)	0.070
Fasl	Fas ligand (TNF superfamily, member 6)	0.070
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.069
Smad7	MAD homolog 7 (Drosophila)	0.069
Col14a1	collagen, type XIV, alpha 1	0.068
Ids	iduronate 2-sulfatase	0.068
Ntf3	neurotrophin 3	0.068
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.068
Irf8	interferon regulatory factor 8	0.068
Col15a1	collagen, type XV, alpha 1	0.068
Prkcd	protein kinase C, delta	0.067
Lima1	LIM domain and actin binding 1	0.067
Hnf4a	hepatic nuclear factor 4, alpha	0.067
Trim47	tripartite motif-containing 47	0.067
Plau	plasminogen activator, urokinase	0.067	Mouse
Hoxd13	homeobox D13	0.066
Htt	huntingtin	0.066	Human
Icam1	intercellular adhesion molecule 1	0.066	Human
Ngf	nerve growth factor	0.065
Ednra	endothelin receptor type A	0.065
Huwe1	HECT, UBA and WWE domain containing 1	0.065
Ccr7	chemokine (C-C motif) receptor 7	0.065	Mouse
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.065
Itga2	integrin alpha 2	0.065
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.065	Human
Nobox	NOBOX oogenesis homeobox	0.065
Stxbp5	syntaxin binding protein 5 (tomosyn)	0.064
Bdkrb2	bradykinin receptor, beta 2	0.064
Chl1	cell adhesion molecule with homology to L1CAM	0.064
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.064
Gbp7	guanylate binding protein 7	0.064
Ldlr	low density lipoprotein receptor	0.064
Gata3	GATA binding protein 3	0.064
Epha2	Eph receptor A2	0.064
Sptlc2	serine palmitoyltransferase, long chain base subunit 2	0.064
Dll4	delta-like 4 (Drosophila)	0.063
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.063
Itgav	integrin alpha V	0.063	Human
Mecom	MDS1 and EVI1 complex locus	0.063
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.063
Lcor	ligand dependent nuclear receptor corepressor	0.063
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.062
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.062
Guca2a	guanylate cyclase activator 2a (guanylin)	0.062
Plcb1	phospholipase C, beta 1	0.062
Homer1	homer homolog 1 (Drosophila)	0.061
Gli2	GLI-Kruppel family member GLI2	0.061
Ptgfr	prostaglandin F receptor	0.061
Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)	0.061
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.061
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.061
Pyhin1	pyrin and HIN domain family, member 1	0.060
C5ar1	complement component 5a receptor 1	0.060
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.060
Blk	B lymphoid kinase	0.060
Zeb1	zinc finger E-box binding homeobox 1	0.060
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.060
Ccr8	chemokine (C-C motif) receptor 8	0.060	Mouse
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.059
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.059
Cd22	CD22 antigen	0.059	Mouse
Flii	flightless I homolog (Drosophila)	0.059
Pltp	phospholipid transfer protein	0.059
Lamc1	laminin, gamma 1	0.059
Bmp2	bone morphogenetic protein 2	0.059
Gna11	guanine nucleotide binding protein, alpha 11	0.059
Mc5r	melanocortin 5 receptor	0.058
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.058
Csf1r	colony stimulating factor 1 receptor	0.058
Rab4b	RAB4B, member RAS oncogene family	0.058
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.058
Thbs2	thrombospondin 2	0.058
F2r	coagulation factor II (thrombin) receptor	0.058
Mvp	major vault protein	0.058
Rb1	retinoblastoma 1	0.057
Casp7	caspase 7	0.057	Mouse
Grb10	growth factor receptor bound protein 10	0.057
Fgf10	fibroblast growth factor 10	0.057
Ifnb1	interferon beta 1, fibroblast	0.057
En1	engrailed 1	0.057
Fgg	fibrinogen gamma chain	0.057
Prox1	prospero-related homeobox 1	0.057
Apaf1	apoptotic peptidase activating factor 1	0.057
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.057
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.057
Sykb	spleen tyrosine kinase	0.057
Mapk1	mitogen-activated protein kinase 1	0.057
Stub1	STIP1 homology and U-Box containing protein 1	0.056
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.056
Gp9	glycoprotein 9 (platelet)	0.056
Il2ra	interleukin 2 receptor, alpha chain	0.055
Wnt7a	wingless-related MMTV integration site 7A	0.055
Fut4	fucosyltransferase 4	0.055
Ccrl2	chemokine (C-C motif) receptor-like 2	0.055	Mouse
Ahsg	alpha-2-HS-glycoprotein	0.055
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.055
Col6a3	collagen, type VI, alpha 3	0.055
Stat1	signal transducer and activator of transcription 1	0.055
Ccr3	chemokine (C-C motif) receptor 3	0.055	Mouse
Irf5	interferon regulatory factor 5	0.055
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.055
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.055
Cmklr1	chemokine-like receptor 1	0.055
Arpc4	actin related protein 2/3 complex, subunit 4	0.054
Stat6	signal transducer and activator of transcription 6	0.054
Gpc3	glypican 3	0.054
Lmnb2	lamin B2	0.054	Mouse
Esr2	estrogen receptor 2 (beta)	0.054
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.054
Socs5	suppressor of cytokine signaling 5	0.054
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.053
Ikzf2	IKAROS family zinc finger 2	0.053
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.053
Fkbp9	FK506 binding protein 9	0.053
Ifngr1	interferon gamma receptor 1	0.053
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.053
Ptch2	patched homolog 2	0.053
Inhbe	inhibin beta E	0.053	Mouse
Csk	c-src tyrosine kinase	0.052
Angpt1	angiopoietin 1	0.052
Usp42	ubiquitin specific peptidase 42	0.052
Ambp	alpha 1 microglobulin/bikunin	0.052
Bdkrb1	bradykinin receptor, beta 1	0.052
Wwox	WW domain-containing oxidoreductase	0.051
Flnb	filamin, beta	0.051
Pou2f2	POU domain, class 2, transcription factor 2	0.051
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.051
Col12a1	collagen, type XII, alpha 1	0.051
Inhbc	inhibin beta-C	0.051
Ptprj	protein tyrosine phosphatase, receptor type, J	0.051
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.051
Capns1	calpain, small subunit 1	0.051
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.051
Gab2	growth factor receptor bound protein 2-associated protein 2	0.051
Col1a2	collagen, type I, alpha 2	0.051	Mouse
Bgn	biglycan	0.050
Prss23	protease, serine, 23	0.050
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.050
Meox1	mesenchyme homeobox 1	0.050
Ltbp2	latent transforming growth factor beta binding protein 2	0.050
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.050
Wnt4	wingless-related MMTV integration site 4	0.049
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.049
Plxna1	plexin A1	0.049
Lama5	laminin, alpha 5	0.049
Atxn1	ataxin 1	0.049
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.049
Fndc1	fibronectin type III domain containing 1	0.049
Mmp16	matrix metallopeptidase 16	0.049
Slamf1	signaling lymphocytic activation molecule family member 1	0.049
Sell	selectin, lymphocyte	0.049
Slfn1	schlafen 1	0.049
Ikbip	IKBKB interacting protein	0.049
Nt5e	5' nucleotidase, ecto	0.049
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.048
Trp73	transformation related protein 73	0.048
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.048
Cd5	CD5 antigen	0.048
Ncr1	natural cytotoxicity triggering receptor 1	0.048
Fgf8	fibroblast growth factor 8	0.048
Pola1	polymerase (DNA directed), alpha 1	0.048
Hck	hemopoietic cell kinase	0.048
Myadm	myeloid-associated differentiation marker	0.048
Vasp	vasodilator-stimulated phosphoprotein	0.048
Barx1	BarH-like homeobox 1	0.048
Cd93	CD93 antigen	0.047
Dmd	dystrophin, muscular dystrophy	0.047
Ednrb	endothelin receptor type B	0.047
Pou3f4	POU domain, class 3, transcription factor 4	0.047
Hspa5	heat shock protein 5	0.047
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.047	Human
Pdgfb	platelet derived growth factor, B polypeptide	0.047	Mouse
Psap	prosaposin	0.047
Phox2b	paired-like homeobox 2b	0.047
Cd86	CD86 antigen	0.047
Inhbb	inhibin beta-B	0.046
Pfn1	profilin 1	0.046
Il7	interleukin 7	0.046
Adora2a	adenosine A2a receptor	0.046
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.046
Prlr	prolactin receptor	0.046
Vcan	versican	0.046
Rhox6	reproductive homeobox 6	0.046
Isl1	ISL1 transcription factor, LIM/homeodomain	0.045
Cd28	CD28 antigen	0.045
Uts2r	urotensin 2 receptor	0.045
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.045
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.045
Mgp	matrix Gla protein	0.045
Jag1	jagged 1	0.045
Vldlr	very low density lipoprotein receptor	0.045
Galr3	galanin receptor 3	0.045
Lrp2	low density lipoprotein receptor-related protein 2	0.045
Apoa1	apolipoprotein A-I	0.045
Elovl1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	0.045
Rad21l	RAD21-like (S. pombe)	0.045
Tnfrsf23	tumor necrosis factor receptor superfamily, member 23	0.045
Mc2r	melanocortin 2 receptor	0.045
Cd40lg	CD40 ligand	0.045
Bbc3	BCL2 binding component 3	0.044
Myh10	myosin, heavy polypeptide 10, non-muscle	0.044
Mest	mesoderm specific transcript	0.044
Hoxa2	homeobox A2	0.044
Epas1	endothelial PAS domain protein 1	0.044
Traf2	TNF receptor-associated factor 2	0.044	Human
Ext1	exostoses (multiple) 1	0.044
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.044
Pkdcc	protein kinase domain containing, cytoplasmic	0.044
Pdpn	podoplanin	0.044
Sfrp5	secreted frizzled-related sequence protein 5	0.044	Mouse
Cd1d2	CD1d2 antigen	0.044
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.044
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.044
Igfbp7	insulin-like growth factor binding protein 7	0.044
Pou2af1	POU domain, class 2, associating factor 1	0.043
Igsf8	immunoglobulin superfamily, member 8	0.043
Retnlb	resistin like beta	0.043
Gbp2	guanylate binding protein 2	0.043
Bst1	bone marrow stromal cell antigen 1	0.043
Igbp1	immunoglobulin (CD79A) binding protein 1	0.043
Tead1	TEA domain family member 1	0.043
Lef1	lymphoid enhancer binding factor 1	0.043
Bmp15	bone morphogenetic protein 15	0.043
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.043
Lrp1	low density lipoprotein receptor-related protein 1	0.043
Cd5l	CD5 antigen-like	0.043
Spry4	sprouty homolog 4 (Drosophila)	0.043
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.043
Ikzf4	IKAROS family zinc finger 4	0.043
Gcet2	germinal center expressed transcript 2	0.043
Oc90	otoconin 90	0.043
Casp12	caspase 12	0.043	Mouse
Lbr	lamin B receptor	0.043
Akap1	A kinase (PRKA) anchor protein 1	0.043
Emx1	empty spiracles homolog 1 (Drosophila)	0.042
Tead3	TEA domain family member 3	0.042
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.042
Smad6	MAD homolog 6 (Drosophila)	0.042
Pdlim5	PDZ and LIM domain 5	0.042
Hic1	hypermethylated in cancer 1	0.042
Rapsn	receptor-associated protein of the synapse	0.042
Cd160	CD160 antigen	0.042
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.042
Gsr	glutathione reductase	0.042
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.042
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.042
Agtr1a	angiotensin II receptor, type 1a	0.042
Wdr1	WD repeat domain 1	0.041
Bcl6b	B-cell CLL/lymphoma 6, member B	0.041
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.041
Cx3cr1	chemokine (C-X3-C) receptor 1	0.041
Usp25	ubiquitin specific peptidase 25	0.041
Vcam1	vascular cell adhesion molecule 1	0.041
Gab1	growth factor receptor bound protein 2-associated protein 1	0.041
Polm	polymerase (DNA directed), mu	0.041
Foxf1a	forkhead box F1a	0.041
Aplnr	apelin receptor	0.041
Blnk	B-cell linker	0.041
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.041
Shh	sonic hedgehog	0.041
Wls	wntless homolog (Drosophila)	0.041
Kit	kit oncogene	0.040
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.040
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.040
Arl10	ADP-ribosylation factor-like 10	0.040
Cfi	complement component factor i	0.040
Pea15a	phosphoprotein enriched in astrocytes 15A	0.040
Nostrin	nitric oxide synthase trafficker	0.040
Sox10	SRY-box containing gene 10	0.040
Slfn3	schlafen 3	0.040
Tll1	tolloid-like	0.040
Rras	Harvey rat sarcoma oncogene, subgroup R	0.040
Psme2	proteasome (prosome, macropain) 28 subunit, beta	0.040
Pdgfc	platelet-derived growth factor, C polypeptide	0.040
Hoxb1	homeobox B1	0.040
Pygb	brain glycogen phosphorylase	0.040
Ptpre	protein tyrosine phosphatase, receptor type, E	0.040	Mouse
Col10a1	collagen, type X, alpha 1	0.040
Pla2r1	phospholipase A2 receptor 1	0.040
Mid1	midline 1	0.040
Prss12	protease, serine, 12 neurotrypsin (motopsin)	0.040
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.040
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.040
Tcf21	transcription factor 21	0.040
Krtap8-1	keratin associated protein 8-1	0.039
Nsd1	nuclear receptor-binding SET-domain protein 1	0.039
Twist2	twist homolog 2 (Drosophila)	0.039
Med14	mediator complex subunit 14	0.039
Sh3pxd2b	SH3 and PX domains 2B	0.039
Tor3a	torsin family 3, member A	0.039
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.039
Tlr6	toll-like receptor 6	0.039
Gltp	glycolipid transfer protein	0.039
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.039
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.039
Prkci	protein kinase C, iota	0.039
Add1	adducin 1 (alpha)	0.039
Masp1	mannan-binding lectin serine peptidase 1	0.039
Dmpk	dystrophia myotonica-protein kinase	0.039
Tgif1	TGFB-induced factor homeobox 1	0.039
Rdh10	retinol dehydrogenase 10 (all-trans)	0.039
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.039
Rhoh	ras homolog gene family, member H	0.039
Pign	phosphatidylinositol glycan anchor biosynthesis, class N	0.038
Adm	adrenomedullin	0.038
Dmtf1	cyclin D binding myb-like transcription factor 1	0.038
Mecp2	methyl CpG binding protein 2	0.038
Arpc1b	actin related protein 2/3 complex, subunit 1B	0.038
Hoxc6	homeobox C6	0.038
Tbx1	T-box 1	0.038
Bglap	bone gamma carboxyglutamate protein	0.038
Axin1	axin 1	0.038
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.038
Ubl4b	ubiquitin-like 4B	0.038
Otp	orthopedia homolog (Drosophila)	0.038
Emp1	epithelial membrane protein 1	0.038
Gpc4	glypican 4	0.038
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.038
Figf	c-fos induced growth factor	0.038	Mouse
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.037
Tmed8	transmembrane emp24 domain containing 8	0.037
Hrc	histidine rich calcium binding protein	0.037
Ebf2	early B-cell factor 2	0.037
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.037
Cd7	CD7 antigen	0.037
Xpa	xeroderma pigmentosum, complementation group A	0.037
Lrmp	lymphoid-restricted membrane protein	0.037
Rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.037
Plg	plasminogen	0.037	Mouse
Cntn4	contactin 4	0.037
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.037
Capn2	calpain 2	0.037
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.037
Igf1	insulin-like growth factor 1	0.037	Human Rat
Atp6v0a4	ATPase, H+ transporting, lysosomal V0 subunit A4	0.037
Il18r1	interleukin 18 receptor 1	0.036
Gna15	guanine nucleotide binding protein, alpha 15	0.036
Mfap2	microfibrillar-associated protein 2	0.036
Frmd6	FERM domain containing 6	0.036
Prdm1	PR domain containing 1, with ZNF domain	0.036
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.036
Fbn2	fibrillin 2	0.036
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.036
Hes1	hairy and enhancer of split 1 (Drosophila)	0.036
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.036
Cxcl2	chemokine (C-X-C motif) ligand 2	0.036
Wnt10a	wingless related MMTV integration site 10a	0.036
Phldb2	pleckstrin homology-like domain, family B, member 2	0.036
Wt1	Wilms tumor 1 homolog	0.036
Traf3	TNF receptor-associated factor 3	0.036
Hoxa11	homeobox A11	0.036
Pzp	pregnancy zone protein	0.036
Slc12a4	solute carrier family 12, member 4	0.035
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.035
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.035
Epha4	Eph receptor A4	0.035
Glg1	golgi apparatus protein 1	0.035
Adam10	a disintegrin and metallopeptidase domain 10	0.035