IMP: Integrative Multi-species Prediction

Mus musculus

28 genes annotated in mouse

dna integrity checkpoint

A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna integrity checkpoint"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "dna integrity checkpoint" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Cdk4	cyclin-dependent kinase 4	0.993
Mapk14	mitogen-activated protein kinase 14	0.921
Brca1	breast cancer 1	0.917	Human
Pten	phosphatase and tensin homolog	0.915
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.855
Rb1	retinoblastoma 1	0.840
Brca2	breast cancer 2	0.832
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.809	Fly
E2f1	E2F transcription factor 1	0.808	Human
Nbn	nibrin	0.780
Clock	circadian locomotor output cycles kaput	0.776	Human
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.750
Atm	ataxia telangiectasia mutated homolog (human)	0.705
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.643
Per2	period homolog 2 (Drosophila)	0.632
Mdm2	transformed mouse 3T3 cell double minute 2	0.622	Human
Atf2	activating transcription factor 2	0.524	Human
Timeless	timeless homolog (Drosophila)	0.515	Fly
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.479
Msh2	mutS homolog 2 (E. coli)	0.441
Mdm4	transformed mouse 3T3 cell double minute 4	0.406
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.396
Tcf3	transcription factor 3	0.347
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.326
Ncoa3	nuclear receptor coactivator 3	0.319
Skil	SKI-like	0.264
Cry1	cryptochrome 1 (photolyase-like)	0.264
Gtse1	G two S phase expressed protein 1	0.257
Zmym5	zinc finger, MYM-type 5	0.240
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.239
Ruvbl2	RuvB-like protein 2	0.207
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.206
Crebbp	CREB binding protein	0.199
Mybl2	myeloblastosis oncogene-like 2	0.193
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.192
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.191
Rbl1	retinoblastoma-like 1 (p107)	0.190	Fly
Cdk1	cyclin-dependent kinase 1	0.174
Cry2	cryptochrome 2 (photolyase-like)	0.158	Mouse
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.154	Fly
H2afx	H2A histone family, member X	0.146	Human
Apc	adenomatosis polyposis coli	0.146
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.136
Cops4	COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)	0.121
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.118
Tcf19	transcription factor 19	0.115
Mapk8	mitogen-activated protein kinase 8	0.109	Mouse
Parp1	poly (ADP-ribose) polymerase family, member 1	0.109
Skp1a	S-phase kinase-associated protein 1A	0.106
Ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.104
Ccnb1	cyclin B1	0.101
Raf1	v-raf-leukemia viral oncogene 1	0.100
Smad4	MAD homolog 4 (Drosophila)	0.099
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.098
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.097
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.097
Gmnn	geminin	0.096
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.095	Yeast
Ccna2	cyclin A2	0.094
Sp1	trans-acting transcription factor 1	0.092
Rfc3	replication factor C (activator 1) 3	0.091
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.088
Ash2l	ash2 (absent, small, or homeotic)-like (Drosophila)	0.088
Xpa	xeroderma pigmentosum, complementation group A	0.081
Pkm2	pyruvate kinase, muscle	0.077
Cops3	COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)	0.077	Fly
Ccnb2	cyclin B2	0.077
Ccnf	cyclin F	0.076
Mlh1	mutL homolog 1 (E. coli)	0.073
Lig1	ligase I, DNA, ATP-dependent	0.073
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.073
Rfc2	replication factor C (activator 1) 2	0.072
Nae1	NEDD8 activating enzyme E1 subunit 1	0.071
Nup85	nucleoporin 85	0.069
Ube3a	ubiquitin protein ligase E3A	0.069
Trp73	transformation related protein 73	0.068	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.065	Human
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.065
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.064
Rad51ap1	RAD51 associated protein 1	0.063
Per1	period homolog 1 (Drosophila)	0.059
Lrrk2	leucine-rich repeat kinase 2	0.058
Sfn	stratifin	0.057	Yeast
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.057
Aurkb	aurora kinase B	0.055
Pou5f1	POU domain, class 5, transcription factor 1	0.055
Hnrnpf	heterogeneous nuclear ribonucleoprotein F	0.054
Hdac1	histone deacetylase 1	0.054
Nono	non-POU-domain-containing, octamer binding protein	0.054
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.053	Yeast
Daxx	Fas death domain-associated protein	0.053
Prc1	protein regulator of cytokinesis 1	0.053
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.052
Cdt1	chromatin licensing and DNA replication factor 1	0.051
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.050
Orc2	origin recognition complex, subunit 2	0.048
Klf5	Kruppel-like factor 5	0.048
Pcna	proliferating cell nuclear antigen	0.048
Cbl	Casitas B-lineage lymphoma	0.047
Terf1	telomeric repeat binding factor 1	0.047
Rpa1	replication protein A1	0.046
Notch1	Notch gene homolog 1 (Drosophila)	0.046
Rara	retinoic acid receptor, alpha	0.045
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.045
Nipbl	Nipped-B homolog (Drosophila)	0.044
Ncaph	non-SMC condensin I complex, subunit H	0.043
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.043
Arid1a	AT rich interactive domain 1A (SWI-like)	0.043
Setdb1	SET domain, bifurcated 1	0.043
Cops2	COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)	0.043
Stag1	stromal antigen 1	0.043
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.042
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.042
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.042
Ncapd2	non-SMC condensin I complex, subunit D2	0.042
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.041
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.041
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.040
Hmgb1	high mobility group box 1	0.040
Cdk2	cyclin-dependent kinase 2	0.040	Mouse
Plk1	polo-like kinase 1 (Drosophila)	0.040	Human
Hells	helicase, lymphoid specific	0.040
Kif11	kinesin family member 11	0.040
B3galnt2	UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2	0.039
Kif2c	kinesin family member 2C	0.039
Nf1	neurofibromatosis 1	0.039
Fbxl3	F-box and leucine-rich repeat protein 3	0.039
Lrdd	leucine-rich and death domain containing	0.039	Human
Zfp871	zinc finger protein 871	0.039
Spnb2	spectrin beta 2	0.038
March7	membrane-associated ring finger (C3HC4) 7	0.038
Tsc1	tuberous sclerosis 1	0.038
Rfc5	replication factor C (activator 1) 5	0.038
Cdca8	cell division cycle associated 8	0.038
Gpi1	glucose phosphate isomerase 1	0.036
Egr2	early growth response 2	0.035
Kif22	kinesin family member 22	0.035
Tmpo	thymopoietin	0.035
Kif20a	kinesin family member 20A	0.035
Ptch1	patched homolog 1	0.034
Cdca7	cell division cycle associated 7	0.034
Mtf2	metal response element binding transcription factor 2	0.034
Wrn	Werner syndrome homolog (human)	0.034
Pask	PAS domain containing serine/threonine kinase	0.034
Rad50	RAD50 homolog (S. cerevisiae)	0.034
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.034
Fam96a	family with sequence similarity 96, member A	0.034
Plagl2	pleiomorphic adenoma gene-like 2	0.033
Sin3a	transcriptional regulator, SIN3A (yeast)	0.033
Kat2a	K(lysine) acetyltransferase 2A	0.033
Ep300	E1A binding protein p300	0.033
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.033
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.032
Pole	polymerase (DNA directed), epsilon	0.032	Yeast
Dennd4c	DENN/MADD domain containing 4C	0.032
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.032
Lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.032
Cdca7l	cell division cycle associated 7 like	0.032
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.032	Yeast
Foxp1	forkhead box P1	0.032
Chd2	chromodomain helicase DNA binding protein 2	0.032
Ctcf	CCCTC-binding factor	0.031
Hcfc1	host cell factor C1	0.031
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.031
Birc5	baculoviral IAP repeat-containing 5	0.031
Cops6	COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)	0.030
Foxo3	forkhead box O3	0.030	Mouse
Lmnb1	lamin B1	0.030
Cdca5	cell division cycle associated 5	0.030
Trp63	transformation related protein 63	0.029	Mouse
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.029
Orc1	origin recognition complex, subunit 1	0.029
Vrk1	vaccinia related kinase 1	0.028
Cul3	cullin 3	0.028
Ints9	integrator complex subunit 9	0.028
Men1	multiple endocrine neoplasia 1	0.028	Fly
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.028
Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	0.028
Fancd2	Fanconi anemia, complementation group D2	0.027
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.027
Ccdc99	coiled-coil domain containing 99	0.027
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.027
H2afy	H2A histone family, member Y	0.027
Scaf11	SR-related CTD-associated factor 11	0.026
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.026
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.026
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.026	Fly
Dtymk	deoxythymidylate kinase	0.026
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.026
Mutyh	mutY homolog (E. coli)	0.025
Racgap1	Rac GTPase-activating protein 1	0.025
A930001N09Rik	RIKEN cDNA A930001N09 gene	0.025
Sox9	SRY-box containing gene 9	0.025
Sall4	sal-like 4 (Drosophila)	0.024
Nfya	nuclear transcription factor-Y alpha	0.024
Rcc2	regulator of chromosome condensation 2	0.024
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.024
Cops8	COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana)	0.024
Mta2	metastasis-associated gene family, member 2	0.024
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.024
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.024
Srsf2	serine/arginine-rich splicing factor 2	0.024
Ewsr1	Ewing sarcoma breakpoint region 1	0.024
Ckap2	cytoskeleton associated protein 2	0.023
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.023
Pgk1	phosphoglycerate kinase 1	0.023
Mudeng	MU-2/AP1M2 domain containing, death-inducing	0.023
Cenpa	centromere protein A	0.023
Mum1	melanoma associated antigen (mutated) 1	0.023
Fbxw7	F-box and WD-40 domain protein 7	0.023
Otud4	OTU domain containing 4	0.023
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.023
Nup107	nucleoporin 107	0.023
Rpgrip1l	Rpgrip1-like	0.023
Tceb3	transcription elongation factor B (SIII), polypeptide 3	0.023
Chek2	CHK2 checkpoint homolog (S. pombe)	0.022	Human Fly
Top2a	topoisomerase (DNA) II alpha	0.022	Yeast
Atrip	ATR interacting protein	0.022
Ints7	integrator complex subunit 7	0.022
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.022
Ralb	v-ral simian leukemia viral oncogene homolog B (ras related)	0.022
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.022
Rpa2	replication protein A2	0.022	Human
Casp2	caspase 2	0.022	Human
Irf1	interferon regulatory factor 1	0.022
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.022
Pum1	pumilio 1 (Drosophila)	0.022
Tdp2	tyrosyl-DNA phosphodiesterase 2	0.022
Nup88	nucleoporin 88	0.021
Braf	Braf transforming gene	0.021
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.021
Aurka	aurora kinase A	0.021	Yeast
Rfc1	replication factor C (activator 1) 1	0.021
Cnot2	CCR4-NOT transcription complex, subunit 2	0.021
Ncor1	nuclear receptor co-repressor 1	0.021
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.020
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.020
Haus5	HAUS augmin-like complex, subunit 5	0.020
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.020
Atad5	ATPase family, AAA domain containing 5	0.020
Mtmr1	myotubularin related protein 1	0.020
Purb	purine rich element binding protein B	0.020
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.020
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.020
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.020
Wdr1	WD repeat domain 1	0.020
Iqgap3	IQ motif containing GTPase activating protein 3	0.020
Cdk9	cyclin-dependent kinase 9 (CDC2-related kinase)	0.019
Med1	mediator complex subunit 1	0.019
Huwe1	HECT, UBA and WWE domain containing 1	0.019
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.019
4833420G17Rik	RIKEN cDNA 4833420G17 gene	0.019
Ubr7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0.019
Ipo11	importin 11	0.019
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.019
E2f8	E2F transcription factor 8	0.019
Txn1	thioredoxin 1	0.019
Trim32	tripartite motif-containing 32	0.019
Tacc3	transforming, acidic coiled-coil containing protein 3	0.019
Caprin1	cell cycle associated protein 1	0.019
Rcc1	regulator of chromosome condensation 1	0.019
Mms22l	MMS22-like, DNA repair protein	0.018
Rbx1	ring-box 1	0.018
Rnf2	ring finger protein 2	0.018
Cops5	COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)	0.018	Fly
Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)	0.018
Tnrc6b	trinucleotide repeat containing 6b	0.018
Csnk1e	casein kinase 1, epsilon	0.018
Thap11	THAP domain containing 11	0.018
Mapk9	mitogen-activated protein kinase 9	0.018	Mouse
Wdfy2	WD repeat and FYVE domain containing 2	0.018
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.018
Rpa3	replication protein A3	0.018
Stat6	signal transducer and activator of transcription 6	0.018
Zfp161	zinc finger protein 161	0.018
Tbp	TATA box binding protein	0.018
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.017
Kdm3a	lysine (K)-specific demethylase 3A	0.017
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.017
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.017
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.017
Smc2	structural maintenance of chromosomes 2	0.017
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Igh	immunoglobulin heavy chain complex	0.017
Rprd1b	regulation of nuclear pre-mRNA domain containing 1B	0.017
Snrnp40	small nuclear ribonucleoprotein 40 (U5)	0.017
Rad51	RAD51 homolog (S. cerevisiae)	0.017
Lsm1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.017
Prim1	DNA primase, p49 subunit	0.017
Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha	0.017
Cdk6	cyclin-dependent kinase 6	0.016
Casp3	caspase 3	0.016
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.016
Dcaf8	DDB1 and CUL4 associated factor 8	0.016
Syce2	synaptonemal complex central element protein 2	0.016
Asxl1	additional sex combs like 1 (Drosophila)	0.016
Ccnd3	cyclin D3	0.016
Nup188	nucleoporin 188	0.016
Trrap	transformation/transcription domain-associated protein	0.016
Prps1l3	phosphoribosyl pyrophosphate synthetase 1-like 3	0.016
Stk11	serine/threonine kinase 11	0.016
Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.016
Mbnl1	muscleblind-like 1 (Drosophila)	0.016
Gabpa	GA repeat binding protein, alpha	0.016
Usp33	ubiquitin specific peptidase 33	0.016
Mns1	meiosis-specific nuclear structural protein 1	0.016
Zfp740	zinc finger protein 740	0.016
Bclaf1	BCL2-associated transcription factor 1	0.016
Hdac2	histone deacetylase 2	0.016
Parp2	poly (ADP-ribose) polymerase family, member 2	0.016
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.016
Snrpb	small nuclear ribonucleoprotein B	0.016
Rint1	RAD50 interactor 1	0.016
Fadd	Fas (TNFRSF6)-associated via death domain	0.016
Orc6	origin recognition complex, subunit 6	0.015
Osbpl11	oxysterol binding protein-like 11	0.015
Psmc3ip	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein	0.015
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.015
Tk1	thymidine kinase 1	0.015
Zbtb45	zinc finger and BTB domain containing 45	0.015
Tcfcp2l1	transcription factor CP2-like 1	0.015
Kif4	kinesin family member 4	0.015
Rrm1	ribonucleotide reductase M1	0.015
Acvr1b	activin A receptor, type 1B	0.015
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.015
Hccs	holocytochrome c synthetase	0.015
Rfc4	replication factor C (activator 1) 4	0.015	Yeast
Ccne1	cyclin E1	0.015
Fancc	Fanconi anemia, complementation group C	0.015
Bptf	bromodomain PHD finger transcription factor	0.015	Fly
E130303B06Rik	RIKEN cDNA E130303B06 gene	0.015
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.015
Tex10	testis expressed gene 10	0.015
Mapkapk2	MAP kinase-activated protein kinase 2	0.015	Human
Pam16	presequence translocase-asssociated motor 16 homolog (S. cerevisiae)	0.014
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.014
Smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.014
Rbbp5	retinoblastoma binding protein 5	0.014
Tubgcp3	tubulin, gamma complex associated protein 3	0.014
Cdc7	cell division cycle 7 (S. cerevisiae)	0.014
Top1	topoisomerase (DNA) I	0.014
Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein	0.014
Brsk2	BR serine/threonine kinase 2	0.014
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.014
Ube2c	ubiquitin-conjugating enzyme E2C	0.014
Ran	RAN, member RAS oncogene family	0.014
Fus	fusion, derived from t(12;16) malignant liposarcoma (human)	0.014
Incenp	inner centromere protein	0.014
Ankhd1	ankyrin repeat and KH domain containing 1	0.014
Gpn3	GPN-loop GTPase 3	0.014
Tia1	cytotoxic granule-associated RNA binding protein 1	0.014
Rc3h1	RING CCCH (C3H) domains 1	0.014
Bard1	BRCA1 associated RING domain 1	0.014
Gps1	G protein pathway suppressor 1	0.014	Fly
Sae1	SUMO1 activating enzyme subunit 1	0.014
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.013
Bod1l	biorientation of chromosomes in cell division 1-like	0.013
Ung	uracil DNA glycosylase	0.013
Bhlhe40	basic helix-loop-helix family, member e40	0.013
Wdr26	WD repeat domain 26	0.013
l7Rn6	lethal, Chr 7, Rinchik 6	0.013
Wwox	WW domain-containing oxidoreductase	0.013
Ppard	peroxisome proliferator activator receptor delta	0.013
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.013
Xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	0.013
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.013
Lmna	lamin A	0.013
Crlf3	cytokine receptor-like factor 3	0.013
Ctnnb1	catenin (cadherin associated protein), beta 1	0.013
Mapk11	mitogen-activated protein kinase 11	0.013	Mouse
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.013
Pold2	polymerase (DNA directed), delta 2, regulatory subunit	0.013
Gys1	glycogen synthase 1, muscle	0.013
Scaf8	SR-related CTD-associated factor 8	0.013
Larp4b	La ribonucleoprotein domain family, member 4B	0.013
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.013
Stk4	serine/threonine kinase 4	0.013
Tonsl	tonsoku-like, DNA repair protein	0.013
Rsf1	remodeling and spacing factor 1	0.013
Mbd4	methyl-CpG binding domain protein 4	0.013
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.013	Fly
Cops7b	COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana)	0.013
Ttk	Ttk protein kinase	0.013
Smn1	survival motor neuron 1	0.013
Dtl	denticleless homolog (Drosophila)	0.013	Human Zebrafish
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.013
Cpsf4	cleavage and polyadenylation specific factor 4	0.013
Trip12	thyroid hormone receptor interactor 12	0.013
1810035L17Rik	RIKEN cDNA 1810035L17 gene	0.013
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.013
Snrpa	small nuclear ribonucleoprotein polypeptide A	0.013
Id1	inhibitor of DNA binding 1	0.013
Elf3	E74-like factor 3	0.013
Traf7	TNF receptor-associated factor 7	0.012
Wnk1	WNK lysine deficient protein kinase 1	0.012
Atr	ataxia telangiectasia and Rad3 related	0.012
Mbtd1	mbt domain containing 1	0.012
Zmynd8	zinc finger, MYND-type containing 8	0.012
Glrx3	glutaredoxin 3	0.012
Srsf4	serine/arginine-rich splicing factor 4	0.012
Map2k6	mitogen-activated protein kinase kinase 6	0.012
Pfkl	phosphofructokinase, liver, B-type	0.012
Setd8	SET domain containing (lysine methyltransferase) 8	0.012	Fly
Blm	Bloom syndrome, RecQ helicase-like	0.012	Human Worm
Zfp148	zinc finger protein 148	0.012
Rttn	rotatin	0.012
Vhl	von Hippel-Lindau tumor suppressor	0.012
Pik3c3	phosphoinositide-3-kinase, class 3	0.012
Nup155	nucleoporin 155	0.012
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.012
Smarcb1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.012
Csde1	cold shock domain containing E1, RNA binding	0.012
Sart3	squamous cell carcinoma antigen recognized by T-cells 3	0.012
Kdm6a	4lysine (K)-specific demethylase 6A	0.012
Terf2	telomeric repeat binding factor 2	0.012
Usp2	ubiquitin specific peptidase 2	0.012
Taf4a	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.012
Irf6	interferon regulatory factor 6	0.012
Nup133	nucleoporin 133	0.012
Mterfd1	MTERF domain containing 1	0.012
Gm5506	predicted gene 5506	0.012
Nup54	nucleoporin 54	0.012
Ranbp3	RAN binding protein 3	0.012
Hexim1	hexamethylene bis-acetamide inducible 1	0.012
Bcl2l1	BCL2-like 1	0.012
Mapk1	mitogen-activated protein kinase 1	0.012
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.012
Arl5b	ADP-ribosylation factor-like 5B	0.012
Creb1	cAMP responsive element binding protein 1	0.012
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.012
Kpna1	karyopherin (importin) alpha 1	0.012
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.012
Eif4a3	eukaryotic translation initiation factor 4A3	0.012
Capn7	calpain 7	0.011
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.011
Haus4	HAUS augmin-like complex, subunit 4	0.011
Rcor2	REST corepressor 2	0.011
Sesn1	sestrin 1	0.011
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.011
Met	met proto-oncogene	0.011
Lmnb2	lamin B2	0.011
Msh6	mutS homolog 6 (E. coli)	0.011
Cenpk	centromere protein K	0.011
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.011
Trim28	tripartite motif-containing 28	0.011
Naa38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.011
Actl6a	actin-like 6A	0.011
Myc	myelocytomatosis oncogene	0.011
Baz2b	bromodomain adjacent to zinc finger domain, 2B	0.011
Impad1	inositol monophosphatase domain containing 1	0.011
Hat1	histone aminotransferase 1	0.011
Dna2	DNA replication helicase 2 homolog (yeast)	0.011	Human
Pde7a	phosphodiesterase 7A	0.011
Pknox1	Pbx/knotted 1 homeobox	0.011
Ireb2	iron responsive element binding protein 2	0.011
Mrpl13	mitochondrial ribosomal protein L13	0.011
Adrbk1	adrenergic receptor kinase, beta 1	0.011
Thoc4	THO complex 4	0.011
Cxcr4	chemokine (C-X-C motif) receptor 4	0.011
Grsf1	G-rich RNA sequence binding factor 1	0.011
Bud31	BUD31 homolog (yeast)	0.011
Ankrd28	ankyrin repeat domain 28	0.011
Pkdcc	protein kinase domain containing, cytoplasmic	0.011
Dlg1	discs, large homolog 1 (Drosophila)	0.011
Hmgb3	high mobility group box 3	0.011
Zfp110	zinc finger protein 110	0.011
Usp15	ubiquitin specific peptidase 15	0.011
Krtcap3	keratinocyte associated protein 3	0.011
Nkap	NFKB activating protein	0.011
Phc2	polyhomeotic-like 2 (Drosophila)	0.011
Hif1a	hypoxia inducible factor 1, alpha subunit	0.011
Cul4a	cullin 4A	0.011
Sox2	SRY-box containing gene 2	0.011
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.011
Capzb	capping protein (actin filament) muscle Z-line, beta	0.011
Prim2	DNA primase, p58 subunit	0.010
Gata4	GATA binding protein 4	0.010
Cdc23	CDC23 (cell division cycle 23, yeast, homolog)	0.010
Brd4	bromodomain containing 4	0.010	Human
Mitf	microphthalmia-associated transcription factor	0.010
Nsmaf	neutral sphingomyelinase (N-SMase) activation associated factor	0.010
4930422G04Rik	RIKEN cDNA 4930422G04 gene	0.010
Sh3bp1	SH3-domain binding protein 1	0.010
2310037I24Rik	RIKEN cDNA 2310037I24 gene	0.010
Foxm1	forkhead box M1	0.010
Ankrd10	ankyrin repeat domain 10	0.010
Nup62	nucleoporin 62	0.010
Cnot7	CCR4-NOT transcription complex, subunit 7	0.010
Nf2	neurofibromatosis 2	0.010
Rfwd2	ring finger and WD repeat domain 2	0.010
Whsc2	Wolf-Hirschhorn syndrome candidate 2 (human)	0.010
Tert	telomerase reverse transcriptase	0.010
Fos	FBJ osteosarcoma oncogene	0.010
Adam17	a disintegrin and metallopeptidase domain 17	0.010
Zfp146	zinc finger protein 146	0.010
Tcf4	transcription factor 4	0.010
Gabpb1	GA repeat binding protein, beta 1	0.010
Ncoa1	nuclear receptor coactivator 1	0.010
Cnot6	CCR4-NOT transcription complex, subunit 6	0.010
Sct	secretin	0.010
Iars2	isoleucine-tRNA synthetase 2, mitochondrial	0.010
Fbxo38	F-box protein 38	0.010
Ubqln4	ubiquilin 4	0.010
Plk4	polo-like kinase 4 (Drosophila)	0.010
Dnm1l	dynamin 1-like	0.010