IMP: Integrative Multi-species Prediction

Mus musculus

159 genes annotated in mouse

regulation of cellular response to stress

Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

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Gene Predictions

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Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	1.000	Fly
Trp53	transformation related protein 53	1.000
Traf6	TNF receptor-associated factor 6	0.999	Human Mouse
Mapk8	mitogen-activated protein kinase 8	0.993	Fly
Mapk14	mitogen-activated protein kinase 14	0.983	Fly
Cd40	CD40 antigen	0.973
Clock	circadian locomotor output cycles kaput	0.952
Cdk4	cyclin-dependent kinase 4	0.951
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.951
Ctnnb1	catenin (cadherin associated protein), beta 1	0.939
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.933
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.917
Atf2	activating transcription factor 2	0.906
Cd44	CD44 antigen	0.902
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.894	Fly
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.888
Tlr4	toll-like receptor 4	0.887
Ccnd1	cyclin D1	0.886
Cav1	caveolin 1, caveolae protein	0.880	Mouse
Cry2	cryptochrome 2 (photolyase-like)	0.872	Mouse
Prkce	protein kinase C, epsilon	0.864
Mdm2	transformed mouse 3T3 cell double minute 2	0.863	Human
Ccl2	chemokine (C-C motif) ligand 2	0.851
Skil	SKI-like	0.826
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.816
C3ar1	complement component 3a receptor 1	0.808
Prnp	prion protein	0.807
Lepr	leptin receptor	0.803
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.796
Tnf	tumor necrosis factor	0.794
Tgfbr2	transforming growth factor, beta receptor II	0.794	Mouse
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.788
Rac1	RAS-related C3 botulinum substrate 1	0.782
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.775	Mouse
Il6st	interleukin 6 signal transducer	0.766	Zebrafish
Igh	immunoglobulin heavy chain complex	0.763
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.743	Mouse
Sqstm1	sequestosome 1	0.730	Human
Fzd8	frizzled homolog 8 (Drosophila)	0.726
Irs1	insulin receptor substrate 1	0.721
Brca1	breast cancer 1	0.706	Human
Per2	period homolog 2 (Drosophila)	0.700
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.694
Mdm4	transformed mouse 3T3 cell double minute 4	0.692
Mef2a	myocyte enhancer factor 2A	0.686
Wnt5a	wingless-related MMTV integration site 5A	0.659
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.655
Klf7	Kruppel-like factor 7 (ubiquitous)	0.654
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.645
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.640	Rat
Axin1	axin 1	0.631
Cxcl13	chemokine (C-X-C motif) ligand 13	0.617
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.610
Shc1	src homology 2 domain-containing transforming protein C1	0.604
Bax	BCL2-associated X protein	0.595	Human Mouse
Msr1	macrophage scavenger receptor 1	0.594
Ccl4	chemokine (C-C motif) ligand 4	0.588	Mouse
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.580	Human Mouse
Stat3	signal transducer and activator of transcription 3	0.578
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.571
Wnt3a	wingless-related MMTV integration site 3A	0.553	Mouse
Brca2	breast cancer 2	0.540
Wdr26	WD repeat domain 26	0.536
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.536
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.532
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.526
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.513
Smad1	MAD homolog 1 (Drosophila)	0.507
Fbxw7	F-box and WD-40 domain protein 7	0.506
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.497	Fly
Mcl1	myeloid cell leukemia sequence 1	0.495
Enah	enabled homolog (Drosophila)	0.494	Mouse
Traf2	TNF receptor-associated factor 2	0.493
Cry1	cryptochrome 1 (photolyase-like)	0.492
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.484
Usp8	ubiquitin specific peptidase 8	0.481
Rb1	retinoblastoma 1	0.480
Grb10	growth factor receptor bound protein 10	0.477
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.475	Human
Gsk3b	glycogen synthase kinase 3 beta	0.474	Fly
Qk	quaking	0.473
Fgfr1	fibroblast growth factor receptor 1	0.473
Klk1b11	kallikrein 1-related peptidase b11	0.473	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.473
Kif1b	kinesin family member 1B	0.470
Met	met proto-oncogene	0.465	Human
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.463
Smad7	MAD homolog 7 (Drosophila)	0.449
Fasl	Fas ligand (TNF superfamily, member 6)	0.445	Mouse
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.443
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.442
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.440
Ephb2	Eph receptor B2	0.437	Mouse
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.431
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.428
Apoe	apolipoprotein E	0.428
Ccl12	chemokine (C-C motif) ligand 12	0.427	Mouse
Sfrp2	secreted frizzled-related protein 2	0.422
Clec4d	C-type lectin domain family 4, member d	0.418
Ccr1	chemokine (C-C motif) receptor 1	0.417
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.417
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.414	Mouse
Rictor	RPTOR independent companion of MTOR, complex 2	0.413
Akt1	thymoma viral proto-oncogene 1	0.413	Rat Fly
Cyld	cylindromatosis (turban tumor syndrome)	0.412
Smad3	MAD homolog 3 (Drosophila)	0.410
Mmp12	matrix metallopeptidase 12	0.407	Mouse
Dab1	disabled homolog 1 (Drosophila)	0.406	Mouse
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.400
Tbx2	T-box 2	0.399
Hif1a	hypoxia inducible factor 1, alpha subunit	0.398	Human Rat
Fgf2	fibroblast growth factor 2	0.395
Tgfbr1	transforming growth factor, beta receptor I	0.393	Mouse
Esr1	estrogen receptor 1 (alpha)	0.389
Chrd	chordin	0.385
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.380
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.374
Mapk9	mitogen-activated protein kinase 9	0.373	Rat Fly
Jun	Jun oncogene	0.373
Cdk2	cyclin-dependent kinase 2	0.369	Yeast
Ccnd2	cyclin D2	0.369
Hdac7	histone deacetylase 7	0.366
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.365
Il1b	interleukin 1 beta	0.365
Vangl1	vang-like 1 (van gogh, Drosophila)	0.363	Mouse
Stag1	stromal antigen 1	0.361
Atm	ataxia telangiectasia mutated homolog (human)	0.357	Human
Ch25h	cholesterol 25-hydroxylase	0.356
Msh2	mutS homolog 2 (E. coli)	0.356
Dab2	disabled homolog 2 (Drosophila)	0.356
Csnk1e	casein kinase 1, epsilon	0.355
Ifng	interferon gamma	0.355
Braf	Braf transforming gene	0.345	Fly
Spna1	spectrin alpha 1	0.344
Pthlh	parathyroid hormone-like peptide	0.339
Pcna	proliferating cell nuclear antigen	0.338
Klk1b3	kallikrein 1-related peptidase b3	0.330	Mouse
Foxo3	forkhead box O3	0.328	Fly
Idua	iduronidase, alpha-L-	0.327
Hdac1	histone deacetylase 1	0.326
Vdr	vitamin D receptor	0.325
Kpna3	karyopherin (importin) alpha 3	0.324
Pnp2	purine-nucleoside phosphorylase 2	0.323
Raf1	v-raf-leukemia viral oncogene 1	0.321	Fly
Tlr2	toll-like receptor 2	0.321	Mouse
Grap2	GRB2-related adaptor protein 2	0.320
Snai1	snail homolog 1 (Drosophila)	0.320	Human
Fgf15	fibroblast growth factor 15	0.313	Human
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.312
Klhl24	kelch-like 24 (Drosophila)	0.308
Mapk1	mitogen-activated protein kinase 1	0.303	Fly
Egr2	early growth response 2	0.302
Prrx2	paired related homeobox 2	0.301
Nbn	nibrin	0.299
Dlg1	discs, large homolog 1 (Drosophila)	0.298
Esr2	estrogen receptor 2 (beta)	0.298
Smad6	MAD homolog 6 (Drosophila)	0.297
Clec4n	C-type lectin domain family 4, member n	0.297
Wnt4	wingless-related MMTV integration site 4	0.297	Mouse
C5ar1	complement component 5a receptor 1	0.295
Foxa2	forkhead box A2	0.293	Worm
Ikbkg	inhibitor of kappaB kinase gamma	0.292
Sox9	SRY-box containing gene 9	0.291
Cyr61	cysteine rich protein 61	0.289
En1	engrailed 1	0.288
Pax1	paired box gene 1	0.288
Gopc	golgi associated PDZ and coiled-coil motif containing	0.288
Pax8	paired box gene 8	0.283
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.282
Klk1	kallikrein 1	0.281	Mouse
Prrx1	paired related homeobox 1	0.280
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.279
Ltb	lymphotoxin B	0.278
Daxx	Fas death domain-associated protein	0.278
Dusp1	dual specificity phosphatase 1	0.278	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.277
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.276
Cdx2	caudal type homeobox 2	0.276
Socs3	suppressor of cytokine signaling 3	0.275	Zebrafish
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.275
Ube2n	ubiquitin-conjugating enzyme E2N	0.273	Human Fly
Ptrf	polymerase I and transcript release factor	0.272
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.271
Tg	thyroglobulin	0.270
Il1rn	interleukin 1 receptor antagonist	0.269	Mouse Rat
Acvr1	activin A receptor, type 1	0.267	Mouse
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.266
Hspa8	heat shock protein 8	0.265
Thbs1	thrombospondin 1	0.264
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.264
Ghr	growth hormone receptor	0.264
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.261
Pcdh12	protocadherin 12	0.259
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.258
Ptk7	PTK7 protein tyrosine kinase 7	0.257
Src	Rous sarcoma oncogene	0.256
Zfand5	zinc finger, AN1-type domain 5	0.256
Fzd4	frizzled homolog 4 (Drosophila)	0.251
Cd14	CD14 antigen	0.250
Cxcr5	chemokine (C-X-C motif) receptor 5	0.250
Bak1	BCL2-antagonist/killer 1	0.250	Mouse
Bag3	BCL2-associated athanogene 3	0.248
Neurog3	neurogenin 3	0.247
Fgf18	fibroblast growth factor 18	0.246
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.246
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.246
Igf1	insulin-like growth factor 1	0.245
2500003M10Rik	RIKEN cDNA 2500003M10 gene	0.244
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.243
Map2k2	mitogen-activated protein kinase kinase 2	0.242	Yeast
Cdk9	cyclin-dependent kinase 9 (CDC2-related kinase)	0.242	Human
Emp2	epithelial membrane protein 2	0.241
Fzd1	frizzled homolog 1 (Drosophila)	0.241	Mouse
Ren1	renin 1 structural	0.241
Pgls	6-phosphogluconolactonase	0.241
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.239
Ptp4a2	protein tyrosine phosphatase 4a2	0.236
Msln	mesothelin	0.233
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.230
Klf6	Kruppel-like factor 6	0.230
Mapk10	mitogen-activated protein kinase 10	0.229	Fly
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.228
Cbl	Casitas B-lineage lymphoma	0.227
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.226
Foxf2	forkhead box F2	0.226
Cd22	CD22 antigen	0.224
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.223
Thra	thyroid hormone receptor alpha	0.223
March7	membrane-associated ring finger (C3HC4) 7	0.222
Hbb-b1	hemoglobin, beta adult major chain	0.222
Chd2	chromodomain helicase DNA binding protein 2	0.220
Mrc2	mannose receptor, C type 2	0.219
Apc	adenomatosis polyposis coli	0.218
Ankrd11	ankyrin repeat domain 11	0.217
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.217
Yap1	yes-associated protein 1	0.217
Cpd	carboxypeptidase D	0.215
Ngf	nerve growth factor	0.215
Ikzf1	IKAROS family zinc finger 1	0.214
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.214
Klf5	Kruppel-like factor 5	0.213
Clec4e	C-type lectin domain family 4, member e	0.212
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.211
Klf13	Kruppel-like factor 13	0.210
Gdf5	growth differentiation factor 5	0.209
Wnt7a	wingless-related MMTV integration site 7A	0.209	Mouse
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.209
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.208
Arrdc3	arrestin domain containing 3	0.208
Hnrnph2	heterogeneous nuclear ribonucleoprotein H2	0.207
Mkl2	MKL/myocardin-like 2	0.207
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.207
Fgfr4	fibroblast growth factor receptor 4	0.206
Pgr	progesterone receptor	0.205
Vasp	vasodilator-stimulated phosphoprotein	0.205	Mouse
Aff4	AF4/FMR2 family, member 4	0.204
Wnt11	wingless-related MMTV integration site 11	0.203	Mouse
Ptk2	PTK2 protein tyrosine kinase 2	0.203
Ikbkb	inhibitor of kappaB kinase beta	0.202
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.201
Ubc	ubiquitin C	0.201
Ccna2	cyclin A2	0.199
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.199
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.199
Gli2	GLI-Kruppel family member GLI2	0.198
Klk1b24	kallikrein 1-related peptidase b24	0.198
Epha4	Eph receptor A4	0.197
Son	Son DNA binding protein	0.197
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.196
Pitx3	paired-like homeodomain transcription factor 3	0.196
Cd19	CD19 antigen	0.196
Mmp10	matrix metallopeptidase 10	0.195	Mouse
Socs1	suppressor of cytokine signaling 1	0.194
Mgat3	mannoside acetylglucosaminyltransferase 3	0.194
Klc1	kinesin light chain 1	0.193
Agtrap	angiotensin II, type I receptor-associated protein	0.193
Tgfb1	transforming growth factor, beta 1	0.193
Becn1	beclin 1, autophagy related	0.193
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.192
Irak3	interleukin-1 receptor-associated kinase 3	0.191	Mouse
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.191
Sav1	salvador homolog 1 (Drosophila)	0.191
Fst	follistatin	0.191
Map2k4	mitogen-activated protein kinase kinase 4	0.191	Zebrafish Mouse Rat Fly
Zcchc14	zinc finger, CCHC domain containing 14	0.190
Hoxd13	homeobox D13	0.190
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.190
Col16a1	collagen, type XVI, alpha 1	0.190
Kif27	kinesin family member 27	0.189
Cxcl2	chemokine (C-X-C motif) ligand 2	0.189
Efna4	ephrin A4	0.188
Mapkapk2	MAP kinase-activated protein kinase 2	0.188	Fly
Arf6	ADP-ribosylation factor 6	0.187
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.186
Rarg	retinoic acid receptor, gamma	0.186
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.186
Plcg1	phospholipase C, gamma 1	0.186
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.186
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.185
Dusp6	dual specificity phosphatase 6	0.185	Mouse
Smo	smoothened homolog (Drosophila)	0.185
Tcf7	transcription factor 7, T-cell specific	0.185
Ltbr	lymphotoxin B receptor	0.184	Human
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.184
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.184
Klk1b5	kallikrein 1-related peptidase b5	0.184	Mouse
Cxcr4	chemokine (C-X-C motif) receptor 4	0.184
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.184
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.182
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.180
Taok1	TAO kinase 1	0.180	Human
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.180
Cul3	cullin 3	0.180
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.180
Ccr2	chemokine (C-C motif) receptor 2	0.179
Ccnb1	cyclin B1	0.179
Clec7a	C-type lectin domain family 7, member a	0.179
Dlg4	discs, large homolog 4 (Drosophila)	0.178
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.177	Fly
Aplp2	amyloid beta (A4) precursor-like protein 2	0.176
Ptgir	prostaglandin I receptor (IP)	0.175
Cxcl1	chemokine (C-X-C motif) ligand 1	0.175
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.174	Human
Fbxl3	F-box and leucine-rich repeat protein 3	0.173
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.173
Gdnf	glial cell line derived neurotrophic factor	0.173
Csnk1a1	casein kinase 1, alpha 1	0.172
Ccl8	chemokine (C-C motif) ligand 8	0.172
Ccl7	chemokine (C-C motif) ligand 7	0.171	Mouse
Ate1	arginyltransferase 1	0.171
Elk4	ELK4, member of ETS oncogene family	0.170
Tbxas1	thromboxane A synthase 1, platelet	0.170
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.169
Prmt1	protein arginine N-methyltransferase 1	0.169
Rab5b	RAB5B, member RAS oncogene family	0.169
Zfp445	zinc finger protein 445	0.168
Ube3a	ubiquitin protein ligase E3A	0.168
Raver2	ribonucleoprotein, PTB-binding 2	0.167
Irs2	insulin receptor substrate 2	0.166
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.166
Irg1	immunoresponsive gene 1	0.165
Smad4	MAD homolog 4 (Drosophila)	0.165
Id2	inhibitor of DNA binding 2	0.164
Klk1b8	kallikrein 1-related peptidase b8	0.164	Mouse
Ptpru	protein tyrosine phosphatase, receptor type, U	0.163	Mouse
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.163
Rsrc2	arginine/serine-rich coiled-coil 2	0.162
Sykb	spleen tyrosine kinase	0.162
Aff1	AF4/FMR2 family, member 1	0.161
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.161
Brd2	bromodomain containing 2	0.161
Sim1	single-minded homolog 1 (Drosophila)	0.159
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.159
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.159
Srcin1	SRC kinase signaling inhibitor 1	0.159
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.158
Trib3	tribbles homolog 3 (Drosophila)	0.158
Ids	iduronate 2-sulfatase	0.158
Apaf1	apoptotic peptidase activating factor 1	0.158
Ece1	endothelin converting enzyme 1	0.158
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.158
Il1a	interleukin 1 alpha	0.157	Mouse
Amotl2	angiomotin-like 2	0.157
Cflar	CASP8 and FADD-like apoptosis regulator	0.156
Kitl	kit ligand	0.156
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.155
Atp11c	ATPase, class VI, type 11C	0.155
Ccnd3	cyclin D3	0.155
Folr2	folate receptor 2 (fetal)	0.155
Ldb3	LIM domain binding 3	0.154
Ager	advanced glycosylation end product-specific receptor	0.153
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.153
Rasip1	Ras interacting protein 1	0.153
Stk11	serine/threonine kinase 11	0.152	Fly
Spnb2	spectrin beta 2	0.151
Luc7l2	LUC7-like 2 (S. cerevisiae)	0.151
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.151
Klk1b21	kallikrein 1-related peptidase b21	0.151	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.150
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.149
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.149
Wt1	Wilms tumor 1 homolog	0.149
Morf4l2	mortality factor 4 like 2	0.149
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.149	Fly
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.149
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.149
Smtn	smoothelin	0.149
Ccl9	chemokine (C-C motif) ligand 9	0.148	Mouse
Nkx3-2	NK3 homeobox 2	0.148
Inhba	inhibin beta-A	0.148
Stk4	serine/threonine kinase 4	0.147	Mouse
App	amyloid beta (A4) precursor protein	0.147
Tgif1	TGFB-induced factor homeobox 1	0.146
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.146
Vangl2	vang-like 2 (van gogh, Drosophila)	0.145
Brd4	bromodomain containing 4	0.145	Human
Dok1	docking protein 1	0.145
Hspa5	heat shock protein 5	0.144
Bdnf	brain derived neurotrophic factor	0.144
Sox7	SRY-box containing gene 7	0.144
Neurog1	neurogenin 1	0.143
Ccl3	chemokine (C-C motif) ligand 3	0.143	Mouse
Utf1	undifferentiated embryonic cell transcription factor 1	0.142
Sesn2	sestrin 2	0.142
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.142
Mapk7	mitogen-activated protein kinase 7	0.142	Human
Smad5	MAD homolog 5 (Drosophila)	0.141
Col4a5	collagen, type IV, alpha 5	0.141
Marveld1	MARVEL (membrane-associating) domain containing 1	0.141
Hnrnpu	heterogeneous nuclear ribonucleoprotein U	0.141
Nrp1	neuropilin 1	0.141
Ip6k1	inositol hexaphosphate kinase 1	0.140
Ahr	aryl-hydrocarbon receptor	0.140
Sfrp1	secreted frizzled-related protein 1	0.139
Kif5b	kinesin family member 5B	0.139
Tgfb2	transforming growth factor, beta 2	0.139	Human
Irak4	interleukin-1 receptor-associated kinase 4	0.139
H2afx	H2A histone family, member X	0.138
Prkci	protein kinase C, iota	0.138
Klk1b16	kallikrein 1-related peptidase b16	0.138	Mouse
Chst2	carbohydrate sulfotransferase 2	0.138
Plau	plasminogen activator, urokinase	0.138
Ddr2	discoidin domain receptor family, member 2	0.138
Casp1	caspase 1	0.138
Cd80	CD80 antigen	0.137
Pxn	paxillin	0.137
Cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.137
Bdkrb2	bradykinin receptor, beta 2	0.137
Med13l	mediator complex subunit 13-like	0.137
Ncoa6	nuclear receptor coactivator 6	0.137
Bcl10	B-cell leukemia/lymphoma 10	0.136
Ednra	endothelin receptor type A	0.136	Mouse
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.135
Slpi	secretory leukocyte peptidase inhibitor	0.135
Kpna1	karyopherin (importin) alpha 1	0.135
Xiap	X-linked inhibitor of apoptosis	0.135
Col1a1	collagen, type I, alpha 1	0.134
Il4	interleukin 4	0.134
Fjx1	four jointed box 1 (Drosophila)	0.134
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.134
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.134
Bcl2l1	BCL2-like 1	0.134	Human Mouse
F2r	coagulation factor II (thrombin) receptor	0.134
Ier2	immediate early response 2	0.133
Vcp	valosin containing protein	0.132
Hnrnpd	heterogeneous nuclear ribonucleoprotein D	0.132
Foxp1	forkhead box P1	0.132
Mfn2	mitofusin 2	0.131
Gas1	growth arrest specific 1	0.131
Fgfr2	fibroblast growth factor receptor 2	0.131
Tbl1x	transducin (beta)-like 1 X-linked	0.131
Ncoa3	nuclear receptor coactivator 3	0.130
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.130
Asxl1	additional sex combs like 1 (Drosophila)	0.129
Kif3a	kinesin family member 3A	0.129
Mmp8	matrix metallopeptidase 8	0.129	Mouse
Il7	interleukin 7	0.128
Fzd9	frizzled homolog 9 (Drosophila)	0.128	Mouse
Irs3	insulin receptor substrate 3	0.128
Ckap2	cytoskeleton associated protein 2	0.128
Plxnd1	plexin D1	0.128
Rab12	RAB12, member RAS oncogene family	0.128
Nlrp3	NLR family, pyrin domain containing 3	0.127	Mouse
Stra6	stimulated by retinoic acid gene 6	0.127
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.127
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.126
Cd86	CD86 antigen	0.126
Traf3	TNF receptor-associated factor 3	0.126	Mouse
Rnf11	ring finger protein 11	0.126
Glis2	GLIS family zinc finger 2	0.125
Nos3	nitric oxide synthase 3, endothelial cell	0.125
Cxcl10	chemokine (C-X-C motif) ligand 10	0.125
Selp	selectin, platelet	0.125
Loxl1	lysyl oxidase-like 1	0.125
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.125
Hlx	H2.0-like homeobox	0.124
Agtr1a	angiotensin II receptor, type 1a	0.124	Mouse
Irf5	interferon regulatory factor 5	0.124
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.124
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.124
Kdr	kinase insert domain protein receptor	0.124
Hipk1	homeodomain interacting protein kinase 1	0.123	Mouse
Twist1	twist homolog 1 (Drosophila)	0.123	Human
Nono	non-POU-domain-containing, octamer binding protein	0.123	Human
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.123
Tcf15	transcription factor 15	0.123
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.123
Trip6	thyroid hormone receptor interactor 6	0.123
Il18rap	interleukin 18 receptor accessory protein	0.122
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.122	Mouse
Barx2	BarH-like homeobox 2	0.122
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.121
Vapa	vesicle-associated membrane protein, associated protein A	0.121
Spp1	secreted phosphoprotein 1	0.121
Rhoh	ras homolog gene family, member H	0.121
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.121
Btg1	B-cell translocation gene 1, anti-proliferative	0.121
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.120
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.120	Fly
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.120
Rnf19a	ring finger protein 19A	0.120
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.119
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.119
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.119
Robo1	roundabout homolog 1 (Drosophila)	0.119
Map2k7	mitogen-activated protein kinase kinase 7	0.118
Fam134b	family with sequence similarity 134, member B	0.118
Cmklr1	chemokine-like receptor 1	0.118
Rbm25	RNA binding motif protein 25	0.117
Gpc3	glypican 3	0.117
Fcgr3	Fc receptor, IgG, low affinity III	0.117	Mouse
Socs5	suppressor of cytokine signaling 5	0.117
Lamc2	laminin, gamma 2	0.116
Rnaseh2b	ribonuclease H2, subunit B	0.116
Ctrb1	chymotrypsinogen B1	0.116
Tsen34	tRNA splicing endonuclease 34 homolog (S. cerevisiae)	0.116
Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	0.116
Zfp358	zinc finger protein 358	0.115
Fcgr1	Fc receptor, IgG, high affinity I	0.115	Mouse
Fgf7	fibroblast growth factor 7	0.115
Npc1	Niemann Pick type C1	0.115
Reln	reelin	0.115
Aplp1	amyloid beta (A4) precursor-like protein 1	0.115
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.115
Tal2	T-cell acute lymphocytic leukemia 2	0.114
Csnk1d	casein kinase 1, delta	0.113
Tgif2	TGFB-induced factor homeobox 2	0.113
Arl4c	ADP-ribosylation factor-like 4C	0.113
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.113
Hand2	heart and neural crest derivatives expressed transcript 2	0.113
Acvrl1	activin A receptor, type II-like 1	0.113	Mouse
Sstr4	somatostatin receptor 4	0.113
Cacybp	calcyclin binding protein	0.113
Gnrhr	gonadotropin releasing hormone receptor	0.112
Pdx1	pancreatic and duodenal homeobox 1	0.112
Srsf3	serine/arginine-rich splicing factor 3	0.112
Tead2	TEA domain family member 2	0.112
Otp	orthopedia homolog (Drosophila)	0.111
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.111
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.111
Vegfc	vascular endothelial growth factor C	0.110
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.110
Snn	stannin	0.110
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.110
Ptprs	protein tyrosine phosphatase, receptor type, S	0.109	Mouse
Sox18	SRY-box containing gene 18	0.109
Rnf111	ring finger 111	0.109
Agrn	agrin	0.109
Tcf3	transcription factor 3	0.109
Rfwd2	ring finger and WD repeat domain 2	0.109
Lta	lymphotoxin A	0.109	Mouse
Rnf8	ring finger protein 8	0.109
Gnl3	guanine nucleotide binding protein-like 3 (nucleolar)	0.108
Prc1	protein regulator of cytokinesis 1	0.108
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.108
Cnn1	calponin 1	0.107
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.107
Epas1	endothelial PAS domain protein 1	0.107
Foxf1a	forkhead box F1a	0.107
Wrn	Werner syndrome homolog (human)	0.106
Rnd3	Rho family GTPase 3	0.106
Gnao1	guanine nucleotide binding protein, alpha O	0.106
Rab10	RAB10, member RAS oncogene family	0.106	Mouse
Bcl6	B-cell leukemia/lymphoma 6	0.106
Hgf	hepatocyte growth factor	0.106	Human Rat
Clec4a2	C-type lectin domain family 4, member a2	0.105
Timp3	tissue inhibitor of metalloproteinase 3	0.105
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.105
Ccdc99	coiled-coil domain containing 99	0.105
Matr3	matrin 3	0.105
Mapkap1	mitogen-activated protein kinase associated protein 1	0.105
Sult5a1	sulfotransferase family 5A, member 1	0.104
Ccnb2	cyclin B2	0.104
Igfbp4	insulin-like growth factor binding protein 4	0.104
Timp1	tissue inhibitor of metalloproteinase 1	0.104
Ranbp1	RAN binding protein 1	0.104
Fbn1	fibrillin 1	0.104
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.104	Mouse
Huwe1	HECT, UBA and WWE domain containing 1	0.104
Cd300ld	CD300 molecule-like family member d	0.104
Tenc1	tensin like C1 domain-containing phosphatase	0.104
Zswim6	zinc finger, SWIM domain containing 6	0.103
Efs	embryonal Fyn-associated substrate	0.103
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.103
Egr1	early growth response 1	0.103
Crabp2	cellular retinoic acid binding protein II	0.102
Ggt5	gamma-glutamyltransferase 5	0.102
Adcy9	adenylate cyclase 9	0.102
Cdk14	cyclin-dependent kinase 14	0.102
Fndc7	fibronectin type III domain containing 7	0.102
Xcl1	chemokine (C motif) ligand 1	0.102	Mouse
Fcgr4	Fc receptor, IgG, low affinity IV	0.102
Iqcb1	IQ calmodulin-binding motif containing 1	0.102
Btk	Bruton agammaglobulinemia tyrosine kinase	0.102
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.102
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.101
Rem1	rad and gem related GTP binding protein 1	0.101
Cdx1	caudal type homeobox 1	0.101
Sp1	trans-acting transcription factor 1	0.101
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.101
Ift57	intraflagellar transport 57 homolog (Chlamydomonas)	0.101
AI428936	expressed sequence AI428936	0.101
Bmp4	bone morphogenetic protein 4	0.100
Nf1	neurofibromatosis 1	0.100
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.100
Cdh5	cadherin 5	0.100
Pvrl1	poliovirus receptor-related 1	0.100
Hdgf	hepatoma-derived growth factor	0.100
Hck	hemopoietic cell kinase	0.099
Hip1	huntingtin interacting protein 1	0.099
Slc12a6	solute carrier family 12, member 6	0.099
Rara	retinoic acid receptor, alpha	0.099
Flt3	FMS-like tyrosine kinase 3	0.099
Casp3	caspase 3	0.099
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.099
Homer1	homer homolog 1 (Drosophila)	0.099
Ldlr	low density lipoprotein receptor	0.098
Rnf41	ring finger protein 41	0.098
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.098
Dlg2	discs, large homolog 2 (Drosophila)	0.098
Foxk1	forkhead box K1	0.098
Matn4	matrilin 4	0.098
Arhgap1	Rho GTPase activating protein 1	0.098
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.098	Mouse
Runx1	runt related transcription factor 1	0.098
Birc3	baculoviral IAP repeat-containing 3	0.098
Plac1	placental specific protein 1	0.097
Cic	capicua homolog (Drosophila)	0.097
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.097
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.097
Rtn4	reticulon 4	0.097
Ccnt2	cyclin T2	0.097
Sycn	syncollin	0.096
Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.096
Aoah	acyloxyacyl hydrolase	0.096
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.096
Midn	midnolin	0.096
Ccl22	chemokine (C-C motif) ligand 22	0.096
Ewsr1	Ewing sarcoma breakpoint region 1	0.096
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.096	Human Mouse
Bmp6	bone morphogenetic protein 6	0.096
Cpz	carboxypeptidase Z	0.095
Rps3	ribosomal protein S3	0.095
Nme5	non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)	0.095
Lamb3	laminin, beta 3	0.095
Nod2	nucleotide-binding oligomerization domain containing 2	0.095
Plxna1	plexin A1	0.095
Cul7	cullin 7	0.095
Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	0.095
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.095
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.094
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.094
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.094	Human
Adam10	a disintegrin and metallopeptidase domain 10	0.094
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.094
Lbr	lamin B receptor	0.094
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.093
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.093
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.093
Trip12	thyroid hormone receptor interactor 12	0.093	Human
Atxn1	ataxin 1	0.093
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.092
Bmp1	bone morphogenetic protein 1	0.092
Etl4	enhancer trap locus 4	0.092
Pdpn	podoplanin	0.092
Sh3pxd2a	SH3 and PX domains 2A	0.091
Prl3b1	prolactin family 3, subfamily b, member 1	0.091
Galc	galactosylceramidase	0.091
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.091
Lif	leukemia inhibitory factor	0.091
Pde7a	phosphodiesterase 7A	0.091
Nfe2	nuclear factor, erythroid derived 2	0.091	Mouse
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.091
Emid2	EMI domain containing 2	0.091
Ticam1	toll-like receptor adaptor molecule 1	0.091
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.091
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.090
Stam2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.090
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.090
Notch1	Notch gene homolog 1 (Drosophila)	0.090
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.090
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.090
Evl	Ena-vasodilator stimulated phosphoprotein	0.090	Mouse
Wfdc2	WAP four-disulfide core domain 2	0.090
Tert	telomerase reverse transcriptase	0.090
Gja1	gap junction protein, alpha 1	0.089
Parva	parvin, alpha	0.089
F10	coagulation factor X	0.089
Dlx6	distal-less homeobox 6	0.089
Ephb3	Eph receptor B3	0.089	Mouse
Grb2	growth factor receptor bound protein 2	0.089
Rbl2	retinoblastoma-like 2	0.089
Gzmc	granzyme C	0.089
Usp25	ubiquitin specific peptidase 25	0.089
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.089
Shroom1	shroom family member 1	0.089
Fpr2	formyl peptide receptor 2	0.089
Epn1	epsin 1	0.089
Pnliprp2	pancreatic lipase-related protein 2	0.089
Krt81	keratin 81	0.088
Ccna1	cyclin A1	0.088
Clk4	CDC like kinase 4	0.088
Ube2d2	ubiquitin-conjugating enzyme E2D 2	0.088
Slfn4	schlafen 4	0.088
Smok3a	sperm motility kinase 3A	0.088
Vcl	vinculin	0.088
Hic1	hypermethylated in cancer 1	0.088
Egfbp2	epidermal growth factor binding protein type B	0.087
Cnot7	CCR4-NOT transcription complex, subunit 7	0.087
Lrp2	low density lipoprotein receptor-related protein 2	0.087
Pdgfb	platelet derived growth factor, B polypeptide	0.087
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.087
Tbc1d4	TBC1 domain family, member 4	0.087
Rab22a	RAB22A, member RAS oncogene family	0.087
Wnt10b	wingless related MMTV integration site 10b	0.087	Mouse
Gab1	growth factor receptor bound protein 2-associated protein 1	0.087
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.087
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.087
Ryk	receptor-like tyrosine kinase	0.087
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.087
Notch4	Notch gene homolog 4 (Drosophila)	0.086
Scube1	signal peptide, CUB domain, EGF-like 1	0.086
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.086
Sftpc	surfactant associated protein C	0.086
Fth1	ferritin heavy chain 1	0.086
Foxo1	forkhead box O1	0.086	Human Fly
Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	0.086	Human
Atf4	activating transcription factor 4	0.086	Human
Pcdh18	protocadherin 18	0.086
Fos	FBJ osteosarcoma oncogene	0.086
Mzf1	myeloid zinc finger 1	0.086
Msl1	male-specific lethal 1 homolog (Drosophila)	0.086
Hnrpdl	heterogeneous nuclear ribonucleoprotein D-like	0.085
Atf3	activating transcription factor 3	0.085
Fgf21	fibroblast growth factor 21	0.085
Mark1	MAP/microtubule affinity-regulating kinase 1	0.085
Cx3cr1	chemokine (C-X3-C) receptor 1	0.085
Pkn2	protein kinase N2	0.085
Emx2	empty spiracles homolog 2 (Drosophila)	0.085
Cd276	CD276 antigen	0.085
Gtf2i	general transcription factor II I	0.085
Msx3	homeobox, msh-like 3	0.085
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.084
Nobox	NOBOX oogenesis homeobox	0.084
Sik3	SIK family kinase 3	0.084
Pou3f2	POU domain, class 3, transcription factor 2	0.084
Pgf	placental growth factor	0.084
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.084
Mus81	MUS81 endonuclease homolog (yeast)	0.084
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.084