IMP: Integrative Multi-species Prediction

Mus musculus

4 genes annotated in mouse

Multi-species View

activation of nf kappab inducing kinase activity

GO:0007250

The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "activation of nf kappab inducing kinase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "activation of nf kappab inducing kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Map3k7	mitogen-activated protein kinase kinase kinase 7	1.000	Human
Traf6	TNF receptor-associated factor 6	1.000	Human
Ikbkg	inhibitor of kappaB kinase gamma	1.000
Ikbkb	inhibitor of kappaB kinase beta	1.000
Chuk	conserved helix-loop-helix ubiquitous kinase	0.929
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.926
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.919
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.910
Myd88	myeloid differentiation primary response gene 88	0.895
Hspa1b	heat shock protein 1B	0.838
Umod	uromodulin	0.711
Agtr1a	angiotensin II receptor, type 1a	0.559
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.491
Irak3	interleukin-1 receptor-associated kinase 3	0.469
Rnf31	ring finger protein 31	0.378
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.346	Mouse
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.337
Smad1	MAD homolog 1 (Drosophila)	0.286
Ren1	renin 1 structural	0.273
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.253
Tifa	TRAF-interacting protein with forkhead-associated domain	0.253
Gps1	G protein pathway suppressor 1	0.238
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.222
Cd40	CD40 antigen	0.219
Skil	SKI-like	0.182
Ube2n	ubiquitin-conjugating enzyme E2N	0.171
Trafd1	TRAF type zinc finger domain containing 1	0.170
Irak1	interleukin-1 receptor-associated kinase 1	0.167	Human
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.167
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.166
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.139
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.137
Itch	itchy, E3 ubiquitin protein ligase	0.134
Traf3ip2	TRAF3 interacting protein 2	0.109
Birc3	baculoviral IAP repeat-containing 3	0.109
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.097
C4b	complement component 4B (Childo blood group)	0.094
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.092
Hp	haptoglobin	0.089
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.087
Agtr2	angiotensin II receptor, type 2	0.085
Lbp	lipopolysaccharide binding protein	0.084
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.079
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.078
Ecsit	ECSIT homolog (Drosophila)	0.074
Ltbr	lymphotoxin B receptor	0.074
Peli2	pellino 2	0.072
Tmprss11e	transmembrane protease, serine 11e	0.067
Cp	ceruloplasmin	0.065
Cyld	cylindromatosis (turban tumor syndrome)	0.064
Ahr	aryl-hydrocarbon receptor	0.063
F9	coagulation factor IX	0.060
Zmpste24	zinc metallopeptidase, STE24 homolog (S. cerevisiae)	0.057
Map2k4	mitogen-activated protein kinase kinase 4	0.056
Igh	immunoglobulin heavy chain complex	0.054
Gm11567	predicted gene 11567	0.053
Edar	ectodysplasin-A receptor	0.053
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.051
Card11	caspase recruitment domain family, member 11	0.051
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.050
Malt1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.049	Human
Stat3	signal transducer and activator of transcription 3	0.049
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.047	Mouse
Apoc4	apolipoprotein C-IV	0.046
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.045
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.043
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.041
Alb	albumin	0.041
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.041
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.040
Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	0.040
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.040
Sharpin	SHANK-associated RH domain interacting protein	0.040
Il1r1	interleukin 1 receptor, type I	0.039
Apof	apolipoprotein F	0.039
Ahsg	alpha-2-HS-glycoprotein	0.038
Hspa1a	heat shock protein 1A	0.038
Eda	ectodysplasin-A	0.038
Steap4	STEAP family member 4	0.037
Traf2	TNF receptor-associated factor 2	0.037	Human
Eln	elastin	0.036
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.036
Bcl6	B-cell leukemia/lymphoma 6	0.034
Bcl10	B-cell leukemia/lymphoma 10	0.033
Lcn2	lipocalin 2	0.033
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.032
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.032
Slc12a1	solute carrier family 12, member 1	0.031
Smad5	MAD homolog 5 (Drosophila)	0.031
Lepr	leptin receptor	0.031
Jag1	jagged 1	0.031
Kng1	kininogen 1	0.030
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.030
C3	complement component 3	0.030
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.028
F10	coagulation factor X	0.027
Tdo2	tryptophan 2,3-dioxygenase	0.027
Id2	inhibitor of DNA binding 2	0.027
Pi16	peptidase inhibitor 16	0.027
Trp53	transformation related protein 53	0.026
Keg1	kidney expressed gene 1	0.026
Cops6	COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)	0.026
Lcat	lecithin cholesterol acyltransferase	0.026
Mavs	mitochondrial antiviral signaling protein	0.026
Apoh	apolipoprotein H	0.025
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.025
F2	coagulation factor II	0.025
Mup4	major urinary protein 4	0.025
Vav2	vav 2 oncogene	0.024
Adam1a	a disintegrin and metallopeptidase domain 1a	0.024
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.024
Tnip3	TNFAIP3 interacting protein 3	0.023
Pcdhb5	protocadherin beta 5	0.022
Traf3	TNF receptor-associated factor 3	0.022
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.022
Casp8	caspase 8	0.022
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.021
Prelp	proline arginine-rich end leucine-rich repeat	0.021
Mrgpra3	MAS-related GPR, member A3	0.021
Cd177	CD177 antigen	0.021
Clu	clusterin	0.021
Rhbdf1	rhomboid family 1 (Drosophila)	0.021
Vsig4	V-set and immunoglobulin domain containing 4	0.020
Osmr	oncostatin M receptor	0.020
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.020	Mouse
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.020
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.020
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.020
Tollip	toll interacting protein	0.019
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.019
Mrgpra2a	MAS-related GPR, member A2A	0.019
Vtn	vitronectin	0.019
Saa2	serum amyloid A 2	0.019
Npn2	neoplastic progression 2	0.018
Ccl7	chemokine (C-C motif) ligand 7	0.018
Nap1l4	nucleosome assembly protein 1-like 4	0.018
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.018
Polr2c	polymerase (RNA) II (DNA directed) polypeptide C	0.018
Prg4	proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)	0.018
Pah	phenylalanine hydroxylase	0.017
Cd248	CD248 antigen, endosialin	0.017
Orm1	orosomucoid 1	0.017
Sardh	sarcosine dehydrogenase	0.017
Prok2	prokineticin 2	0.017
Hpx	hemopexin	0.017
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.017
Atg16l1	autophagy-related 16-like 1 (yeast)	0.017
Chd1	chromodomain helicase DNA binding protein 1	0.017
Plg	plasminogen	0.017
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.016
Xirp1	xin actin-binding repeat containing 1	0.016
Mettl7b	methyltransferase like 7B	0.016
Zbtb16	zinc finger and BTB domain containing 16	0.016
Gm10369	predicted gene 10369	0.016
Ptgs1	prostaglandin-endoperoxide synthase 1	0.016
Saa4	serum amyloid A 4	0.016
Vdr	vitamin D receptor	0.016
Galntl2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	0.016
Eif1b	eukaryotic translation initiation factor 1B	0.016
Wnk4	WNK lysine deficient protein kinase 4	0.016
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.016	Mouse
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.016
Dnase2b	deoxyribonuclease II beta	0.016
Saa1	serum amyloid A 1	0.015
Rnf8	ring finger protein 8	0.015
Clcn1	chloride channel 1	0.015
Fkbp11	FK506 binding protein 11	0.015
4930430A15Rik	RIKEN cDNA 4930430A15 gene	0.015
Mup3	major urinary protein 3	0.015
Mmp19	matrix metallopeptidase 19	0.015
Abt1	activator of basal transcription 1	0.015
Mapkapk5	MAP kinase-activated protein kinase 5	0.015
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.015
Smad9	MAD homolog 9 (Drosophila)	0.014
Slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.014
Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing	0.014
Elane	elastase, neutrophil expressed	0.014
Fcna	ficolin A	0.014
Psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.014
Aldob	aldolase B, fructose-bisphosphate	0.014
F11	coagulation factor XI	0.014
Ces1c	carboxylesterase 1C	0.014
Saa3	serum amyloid A 3	0.014
Tab3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.014
Zwint	ZW10 interactor	0.014
Afm	afamin	0.014
Rnf41	ring finger protein 41	0.014
Agtrap	angiotensin II, type I receptor-associated protein	0.014
C1ra	complement component 1, r subcomponent A	0.014
Tpsg1	tryptase gamma 1	0.014
Tnfrsf22	tumor necrosis factor receptor superfamily, member 22	0.014
Mmp1b	matrix metallopeptidase 1b (interstitial collagenase)	0.013
Slc15a5	solute carrier family 15, member 5	0.013
Serpina1d	serine (or cysteine) peptidase inhibitor, clade A, member 1D	0.013	Mouse
Dynlt1b	dynein light chain Tctex-type 1D	0.013
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.013
Serpinf1	serine (or cysteine) peptidase inhibitor, clade F, member 1	0.013
Pla2g2e	phospholipase A2, group IIE	0.013
Maml1	mastermind like 1 (Drosophila)	0.013
A2m	alpha-2-macroglobulin	0.013
Ppyr1	pancreatic polypeptide receptor 1	0.013
Slc38a3	solute carrier family 38, member 3	0.013
Fgb	fibrinogen beta chain	0.013
Lect2	leukocyte cell-derived chemotaxin 2	0.013
Slc36a2	solute carrier family 36 (proton/amino acid symporter), member 2	0.013
Gpr142	G protein-coupled receptor 142	0.013
Snrpb	small nuclear ribonucleoprotein B	0.013
2700078E11Rik	RIKEN cDNA 2700078E11 gene	0.013
Serpina3i	serine (or cysteine) peptidase inhibitor, clade A, member 3I	0.013
Lrrn4cl	LRRN4 C-terminal like	0.013
Olfr73	olfactory receptor 73	0.013
Nhej1	nonhomologous end-joining factor 1	0.013
1700022P22Rik	RIKEN cDNA 1700022P22 gene	0.013
Mt1	metallothionein 1	0.013
2310010M20Rik	RIKEN cDNA 2310010M20 gene	0.013
Carns1	carnosine synthase 1	0.012
Ccl11	chemokine (C-C motif) ligand 11	0.012
Rbp4	retinol binding protein 4, plasma	0.012
Tnmd	tenomodulin	0.012
Krt5	keratin 5	0.012
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.012
Tcra	T-cell receptor alpha chain	0.012
Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.012
Tgfbr2	transforming growth factor, beta receptor II	0.012
Fam192a	family with sequence similarity 192, member A	0.012
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.012
Chd2	chromodomain helicase DNA binding protein 2	0.012
Hal	histidine ammonia lyase	0.012
C1rb	complement component 1, r subcomponent B	0.012
Svs3a	seminal vesicle secretory protein 3A	0.012
Adcy6	adenylate cyclase 6	0.012
Gpihbp1	GPI-anchored HDL-binding protein 1	0.012
Atoh8	atonal homolog 8 (Drosophila)	0.012
Pla1a	phospholipase A1 member A	0.012
Scrg1	scrapie responsive gene 1	0.012
Gpr146	G protein-coupled receptor 146	0.012
Gjb1	gap junction protein, beta 1	0.012
Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	0.012
Trem1	triggering receptor expressed on myeloid cells 1	0.012
Gpld1	glycosylphosphatidylinositol specific phospholipase D1	0.012
Cdo1	cysteine dioxygenase 1, cytosolic	0.012
Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.012
Adamtsl4	ADAMTS-like 4	0.012
Fgf1	fibroblast growth factor 1	0.012
Lig3	ligase III, DNA, ATP-dependent	0.011
1110038F14Rik	RIKEN cDNA 1110038F14 gene	0.011
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.011
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.011
Crp	C-reactive protein, pentraxin-related	0.011
Itgbl1	integrin, beta-like 1	0.011
Mmp3	matrix metallopeptidase 3	0.011
Akr1c6	aldo-keto reductase family 1, member C6	0.011
Olfr913	olfactory receptor 913	0.011
D18Ertd653e	DNA segment, Chr 18, ERATO Doi 653, expressed	0.011
Ces3b	carboxylesterase 3B	0.011
Popdc2	popeye domain containing 2	0.011
Olfr1341	olfactory receptor 1341	0.011
Dhx30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.011
Slc13a4	solute carrier family 13 (sodium/sulfate symporters), member 4	0.011
Mrap	melanocortin 2 receptor accessory protein	0.011
H2-M10.2	histocompatibility 2, M region locus 10.2	0.011
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.011
2810455B08Rik	RIKEN cDNA 2810455B08 gene	0.011
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.011
Wisp2	WNT1 inducible signaling pathway protein 2	0.011
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.011
Cops3	COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)	0.011
Cpz	carboxypeptidase Z	0.011
Abca6	ATP-binding cassette, sub-family A (ABC1), member 6	0.011
4930579C15Rik	RIKEN cDNA 4930579C15 gene	0.011
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.011
Ankrd17	ankyrin repeat domain 17	0.011
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.011
Rora	RAR-related orphan receptor alpha	0.011
Hc	hemolytic complement	0.011
Prokr1	prokineticin receptor 1	0.011
Ivl	involucrin	0.011
Hdc	histidine decarboxylase	0.011
Vmn1r56	vomeronasal 1 receptor 56	0.011
Krtap1-3	keratin associated protein 1-3	0.011
Gulo	gulonolactone (L-) oxidase	0.011
6720456H20Rik	RIKEN cDNA 6720456H20 gene	0.011
Gm4884	predicted gene 4884	0.011
Pdcd7	programmed cell death 7	0.011
Svs1	seminal vesicle secretory protein 1	0.011
Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	0.011
Gm6614	predicted gene 6614	0.011
Cfb	complement factor B	0.011
Slc17a2	solute carrier family 17 (sodium phosphate), member 2	0.011
C6	complement component 6	0.011
Zmiz1	zinc finger, MIZ-type containing 1	0.011
Nlrx1	NLR family member X1	0.011
Las1l	LAS1-like (S. cerevisiae)	0.011
Trpv5	transient receptor potential cation channel, subfamily V, member 5	0.011
Kng2	kininogen 2	0.011
Svs3b	seminal vesicle secretory protein 3B	0.011
Olfr891	olfactory receptor 891	0.011
Chrnb4	cholinergic receptor, nicotinic, beta polypeptide 4	0.010
Gm4937	predicted gene 4937	0.010
Olfr1325	olfactory receptor 1325	0.010
Igfl3	IGF-like family member 3	0.010
Ddx19b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b	0.010
Eif4enif1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.010
F5	coagulation factor V	0.010
Fbxo40	F-box protein 40	0.010
Ffar3	free fatty acid receptor 3	0.010
Ccdc154	coiled-coil domain containing 154	0.010
Wipf3	WAS/WASL interacting protein family, member 3	0.010
Ldlrad1	low density lipoprotein receptor class A domain containing 1	0.010
Tas2r125	taste receptor, type 2, member 125	0.010
Rnf11	ring finger protein 11	0.010
Hhipl1	hedgehog interacting protein-like 1	0.010
Tarm1	T cell-interacting, activating receptor on myeloid cells 1	0.010
Ercc3	excision repair cross-complementing rodent repair deficiency, complementation group 3	0.010
Slc25a47	solute carrier family 25, member 47	0.010
Krtap5-5	keratin associated protein 5-5	0.010
Cdk15	cyclin-dependent kinase 15	0.010
Wfdc13	WAP four-disulfide core domain 13	0.010
Apoc2	apolipoprotein C-II	0.010
Cml2	camello-like 2	0.010
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.010
Gc	group specific component	0.010
Tigd4	tigger transposable element derived 4	0.010
Ifna11	interferon alpha 11	0.010
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.010
Kynu	kynureninase (L-kynurenine hydrolase)	0.010
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.010
Fam115e	family with sequence similarity 115, member E	0.010
Gzme	granzyme E	0.010