IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

negative regulation of interferon beta production

GO:0032688

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interferon beta production"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of interferon beta production" (in gray)

Name	Description	Probability	Func Analog Organism
Stat2	signal transducer and activator of transcription 2	0.730
Irgm2	immunity-related GTPase family M member 2	0.579
Sfpi1	SFFV proviral integration 1	0.431
Usp18	ubiquitin specific peptidase 18	0.410
Uba7	ubiquitin-like modifier activating enzyme 7	0.350
Stat1	signal transducer and activator of transcription 1	0.290
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.253
Aim2	absent in melanoma 2	0.252
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.236
Isg15	ISG15 ubiquitin-like modifier	0.200
Rsad2	radical S-adenosyl methionine domain containing 2	0.187
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.158
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.152
Bcl3	B-cell leukemia/lymphoma 3	0.152
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.150
Gbp7	guanylate binding protein 7	0.149
Igtp	interferon gamma induced GTPase	0.145
Gbp5	guanylate binding protein 5	0.131
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.101
Gbp3	guanylate binding protein 3	0.083
Casp1	caspase 1	0.082
Trim21	tripartite motif-containing 21	0.078
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.076
Tapbp	TAP binding protein	0.075
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.074
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.070
Irf7	interferon regulatory factor 7	0.069	Mouse
Cd79b	CD79B antigen	0.058
Parp10	poly (ADP-ribose) polymerase family, member 10	0.053
Znfx1	zinc finger, NFX1-type containing 1	0.053
Irgm1	immunity-related GTPase family M member 1	0.049
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.048
Tor3a	torsin family 3, member A	0.046
Irf4	interferon regulatory factor 4	0.042	Mouse
Ifnar2	interferon (alpha and beta) receptor 2	0.041
Mx1	myxovirus (influenza virus) resistance 1	0.040
Cd19	CD19 antigen	0.040
Rtp4	receptor transporter protein 4	0.038
Zbp1	Z-DNA binding protein 1	0.036
Mx2	myxovirus (influenza virus) resistance 2	0.035
Ifi47	interferon gamma inducible protein 47	0.034
Nlrp3	NLR family, pyrin domain containing 3	0.033
Ikzf1	IKAROS family zinc finger 1	0.033
Sykb	spleen tyrosine kinase	0.033
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.032
Ciita	class II transactivator	0.032
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.031
Dock2	dedicator of cyto-kinesis 2	0.031
Sp100	nuclear antigen Sp100	0.027
Irf9	interferon regulatory factor 9	0.027	Mouse
Il27ra	interleukin 27 receptor, alpha	0.027
Oas2	2'-5' oligoadenylate synthetase 2	0.026
Parp14	poly (ADP-ribose) polymerase family, member 14	0.026
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.026
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.025
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.025
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.024
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.024
Rnf31	ring finger protein 31	0.024
Traf2	TNF receptor-associated factor 2	0.023
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.023
Irf1	interferon regulatory factor 1	0.023	Mouse
H2-DMa	histocompatibility 2, class II, locus DMa	0.022
Mfn1	mitofusin 1	0.022
Oas1a	2'-5' oligoadenylate synthetase 1A	0.022
Traf6	TNF receptor-associated factor 6	0.022
Irf8	interferon regulatory factor 8	0.022	Mouse
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.022
Prkcd	protein kinase C, delta	0.021
Pml	promyelocytic leukemia	0.021
Cd72	CD72 antigen	0.021
Ifi44	interferon-induced protein 44	0.019
Batf	basic leucine zipper transcription factor, ATF-like	0.019
AW112010	expressed sequence AW112010	0.018
Cd40	CD40 antigen	0.018
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.018
Ccl5	chemokine (C-C motif) ligand 5	0.017
Cxcl10	chemokine (C-X-C motif) ligand 10	0.017
Blnk	B-cell linker	0.017
Pou2af1	POU domain, class 2, associating factor 1	0.017
Adar	adenosine deaminase, RNA-specific	0.017
BC006779	cDNA sequence BC006779	0.016
Cxcl9	chemokine (C-X-C motif) ligand 9	0.016
Aim1	absent in melanoma 1	0.016
Jak3	Janus kinase 3	0.015
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.014
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.014
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.014
Bst2	bone marrow stromal cell antigen 2	0.014
Isg20	interferon-stimulated protein	0.014
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.014
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.014
Tgtp2	T-cell specific GTPase 2	0.014
Ltb	lymphotoxin B	0.014
Samhd1	SAM domain and HD domain, 1	0.014
Ccr2	chemokine (C-C motif) receptor 2	0.014
Igh	immunoglobulin heavy chain complex	0.014
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.013
Dsp	desmoplakin	0.013
Card11	caspase recruitment domain family, member 11	0.013
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.013
Ikzf3	IKAROS family zinc finger 3	0.012
Zfp524	zinc finger protein 524	0.012
Becn1	beclin 1, autophagy related	0.012
Trim25	tripartite motif-containing 25	0.012
Plcg2	phospholipase C, gamma 2	0.012
Mvp	major vault protein	0.012
BC013712	cDNA sequence BC013712	0.012
Unc93b1	unc-93 homolog B1 (C. elegans)	0.012
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.012
2310044G17Rik	RIKEN cDNA 2310044G17 gene	0.012
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.012
Sfn	stratifin	0.012
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.011
H2-M3	histocompatibility 2, M region locus 3	0.011
H2-K1	histocompatibility 2, K1, K region	0.011
Irf5	interferon regulatory factor 5	0.011	Mouse
Icos	inducible T-cell co-stimulator	0.011
Pex6	peroxisomal biogenesis factor 6	0.011
Ifnar1	interferon (alpha and beta) receptor 1	0.011
Apol9a	apolipoprotein L 9a	0.011
C2	complement component 2 (within H-2S)	0.011
H2-Oa	histocompatibility 2, O region alpha locus	0.011
Birc3	baculoviral IAP repeat-containing 3	0.011
Icam1	intercellular adhesion molecule 1	0.011
Anxa11	annexin A11	0.011
Lgals9	lectin, galactose binding, soluble 9	0.011
Bcl6	B-cell leukemia/lymphoma 6	0.011
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.010
Cd28	CD28 antigen	0.010
Marveld2	MARVEL (membrane-associating) domain containing 2	0.010
Rnf135	ring finger protein 135	0.010
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.010
Cd22	CD22 antigen	0.010