IMP: Integrative Multi-species Prediction

Rattus norvegicus

4 genes annotated in rat

response to tumor cell

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to tumor cell"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to tumor cell" (in gray)

Name	Description	Probability	Func Analog Organism
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.891
Hspa8	heat shock protein 8	0.821
Sell	selectin L	0.654
Gzmb	granzyme B	0.483
Nkg7	natural killer cell group 7 sequence	0.464
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.317
Cd247	Cd247 molecule	0.271
Gzmk	granzyme K	0.241
Ccl5	chemokine (C-C motif) ligand 5	0.225
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.208	Rat
Ccr2	chemokine (C-C motif) receptor 2	0.200
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.183	Rat
Reg3g	regenerating islet-derived 3 gamma	0.175
Cd8a	CD8a molecule	0.165
Hsph1	heat shock 105/110 protein 1	0.158
Gzmm	granzyme M (lymphocyte met-ase 1)	0.156
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.146
Tcrb	T-cell receptor beta chain	0.138
Hspe1	heat shock protein 1 (chaperonin 10)	0.137
Mmp12	matrix metallopeptidase 12	0.128
Prf1	perforin 1 (pore forming protein)	0.124	Mouse
Cd2	Cd2 molecule	0.119
Xcl1	chemokine (C motif) ligand 1	0.113
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.112
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.109
Zap70	zeta-chain (TCR) associated protein kinase	0.097
Il7r	interleukin 7 receptor	0.095
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.090
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.084
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.081
Serpinb3a	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A	0.079
Ubd	ubiquitin D	0.078
Mcpt8	mast cell protease 8	0.076
Oprm1	opioid receptor, mu 1	0.074
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.072
Igsf6	immunoglobulin superfamily, member 6	0.072
Slc25a5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	0.071
Rgs1	regulator of G-protein signaling 1	0.069
Il2rb	interleukin 2 receptor, beta	0.069
Cd3g	CD3 molecule, gamma	0.067
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.058
LOC300024	similar to Ly6-B antigen gene	0.055
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.053	Rat
Hspa5	heat shock protein 5	0.053
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.052
Clec9a	C-type lectin domain family 9, member a	0.052	Rat
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.051
Sval2	seminal vesicle antigen-like 2	0.051
Snrpe	small nuclear ribonucleoprotein polypeptide E	0.050
Ccl4	chemokine (C-C motif) ligand 4	0.049
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.048
Il1rl1	interleukin 1 receptor-like 1	0.043
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.043
Gpx2	glutathione peroxidase 2	0.042
Mcpt3	mast cell peptidase 3	0.041
Fut9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.040
Rps27l	ribosomal protein S27-like	0.039
Reg3b	regenerating islet-derived 3 beta	0.038
Art2	ADP-ribosyltransferase 2	0.038
Dlst	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	0.037
LOC681996	similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 1	0.037
Sit1	signaling threshold regulating transmembrane adaptor 1	0.037
Faslg	Fas ligand (TNF superfamily, member 6)	0.037
Vom1r93	vomeronasal 1 receptor 93	0.036
Igfl3	IGF-like family member 3	0.035
Atp5b	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.033
Pdia6	protein disulfide isomerase family A, member 6	0.033
Havcr1	hepatitis A virus cellular receptor 1	0.033
RGD1304644	similar to RIKEN cDNA 2310046K01	0.032
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.032
Pou1f1	POU class 1 homeobox 1	0.032
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.032
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.031
Gimap4	GTPase, IMAP family member 4	0.031
Nudc	nuclear distribution gene C homolog (A. nidulans)	0.031
Calcr	calcitonin receptor	0.030
Ccl2	chemokine (C-C motif) ligand 2	0.030
Tlr7	toll-like receptor 7	0.030
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.030
Pcna	proliferating cell nuclear antigen	0.029
Skap1	src kinase associated phosphoprotein 1	0.029
Slamf9	SLAM family member 9	0.029
Neurl3	neuralized homolog 3 (Drosophila)	0.029
Cpb1	carboxypeptidase B1 (tissue)	0.028
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.028
Spef2	sperm flagellar 2	0.028
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.028
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.028
Slfn3	schlafen 3	0.028
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.028
Oas1b	2-5 oligoadenylate synthetase 1B	0.028
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.028	Rat
Klre1	killer cell lectin-like receptor, family E, member 1	0.027
Blk	B lymphoid tyrosine kinase	0.027
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.026
LOC100361706	lambda-chain C1-region-like	0.026
Myc	myelocytomatosis oncogene	0.026
Gckr	glucokinase (hexokinase 4) regulator	0.026
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.026
C1qbp	complement component 1, q subcomponent binding protein	0.026
Phb2	prohibitin 2	0.025
Dpep1	dipeptidase 1 (renal)	0.025
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.025	Rat
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.025
Cxcl10	chemokine (C-X-C motif) ligand 10	0.025
Phemx	pan hematopoietic expression	0.025
Chordc1	cysteine and histidine-rich domain (CHORD)-containing 1	0.024
Ccl9	chemokine (C-C motif) ligand 9	0.024
Cst7	cystatin F (leukocystatin)	0.024
Cd22	CD22 molecule	0.023
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.023
RGD1311300	similar to T cell receptor V delta 6	0.023
Ccr5	chemokine (C-C motif) receptor 5	0.023
Mtch2	mitochondrial carrier homolog 2 (C. elegans)	0.023
Klra22	killer cell lectin-like receptor subfamily A, member 22	0.023	Rat
LOC690020	similar to killer cell lectin-like receptor, subfamily A, member 17	0.023	Rat
Slc25a3	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3	0.023
Sh2d1a	SH2 domain protein 1A	0.023
LOC24906	RoBo-1	0.023
Expi	extracellular proteinase inhibitor	0.022
Nox4	NADPH oxidase 4	0.022
Hnf1b	HNF1 homeobox B	0.022
Ifng	interferon gamma	0.022
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.022
Mcpt4	mast cell protease 4	0.021
Gpr114	G protein-coupled receptor 114	0.021
Zcwpw1	zinc finger, CW-type with PWWP domain 1	0.021
Cd244	Cd244 molecule, natural killer cell receptor 2B4	0.021
Gimap6	GTPase, IMAP family member 6	0.020
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.020
Slc20a1	solute carrier family 20 (phosphate transporter), member 1	0.020
Stx17	syntaxin 17	0.020
Spn	sialophorin	0.019
Gzma	granzyme A	0.019
Pgam1	phosphoglycerate mutase 1 (brain)	0.019
Psbpc2	prostatic steroid-binding protein C2	0.019
Ccl19	chemokine (C-C motif) ligand 19	0.019
Slpi	secretory leukocyte peptidase inhibitor	0.019
Ccl20	chemokine (C-C motif) ligand 20	0.019
LOC690418	similar to Acidic proline-rich protein PRP25 precursor	0.018
Ccl7	chemokine (C-C motif) ligand 7	0.018
Odc1	ornithine decarboxylase 1	0.018
Olr1697	olfactory receptor 1697	0.018
Pgk1	phosphoglycerate kinase 1	0.018
Cd5	Cd5 molecule	0.018
Il10ra	interleukin 10 receptor, alpha	0.018
Sh2d2a	SH2 domain protein 2A	0.018
Fh1	fumarate hydratase 1	0.018
Prl2b1	Prolactin family 2, subfamily b, member 1	0.017
Vom1r102	vomeronasal 1 receptor 102	0.017
Olr1654	olfactory receptor 1654	0.017
Stab2	stabilin 2	0.017
Vcsa2	variable coding sequence A2	0.017
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.017
Atf3	activating transcription factor 3	0.017
Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	0.017
RGD1307752	similar to RIKEN cDNA 1110008F13	0.017
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.017
Phex	phosphate regulating endopeptidase homolog, X-linked	0.017
Cd69	Cd69 molecule	0.017	Rat
Slc12a1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.017
Slc36a2	solute carrier family 36 (proton/amino acid symporter), member 2	0.016
Fam65b	family with sequence similarity 65, member B	0.016
Ptprcap	protein tyrosine phosphatase, receptor type, C-associated protein	0.016
Tas2r105	taste receptor, type 2, member 105	0.016
Testin	testin gene	0.016
Gfra3	GDNF family receptor alpha 3	0.016
Epsti1	epithelial stromal interaction 1 (breast)	0.016
Itgal	integrin, alpha L	0.016
Kynu	kynureninase (L-kynurenine hydrolase)	0.016
Pate4	prostate and testis expressed 4	0.016
Psgb1	pregnancy-specific beta 1-glycoprotein	0.016
S100g	S100 calcium binding protein G	0.016
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.015
Gstm3	glutathione S-transferase mu 3	0.015
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.015
Oasl	2'-5'-oligoadenylate synthetase-like	0.015
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.015
Junb	jun B proto-oncogene	0.015
Lrrc59	leucine rich repeat containing 59	0.015
Oas1a	2'-5' oligoadenylate synthetase 1A	0.015
Cela1	chymotrypsin-like elastase family, member 1	0.015
Rnd1	Rho family GTPase 1	0.015
Prl3d4	prolactin family 3, subfamily d, member 4	0.015
Inpp4b	inositol polyphosphate-4-phosphatase, type II	0.015
Epb41l4b	erythrocyte membrane protein band 4.1 like 4B	0.015
Prdm1	PR domain containing 1, with ZNF domain	0.015
Zbp1	Z-DNA binding protein 1	0.014
Cd72	Cd72 molecule	0.014
Kcnv1	potassium channel, subfamily V, member 1	0.014
Gpr183	G protein-coupled receptor 183	0.014
Mepe	matrix extracellular phosphoglycoprotein	0.014
Il6	interleukin 6	0.014
RGD1561343	similar to C20orf118	0.014
Ccr6	chemokine (C-C motif) receptor 6	0.014
Glyat	glycine-N-acyltransferase	0.014
Lrrc4	leucine rich repeat containing 4	0.014
Csn1s1	casein alpha s1	0.014
Apex1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.014
Arhgap4	Rho GTPase activating protein 4	0.014
Ly49si1	immunoreceptor Ly49si1	0.013	Rat
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.013
Cd200r2	Cd200 receptor 2	0.013
Serpinb7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.013
Exo1	exonuclease 1	0.013
Unc5cl	unc-5 homolog C (C. elegans)-like	0.013
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.013
Gzmc	granzyme C	0.013
Stfa2l3	stefin A2-like 3	0.013
Trat1	T cell receptor associated transmembrane adaptor 1	0.013
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.013
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.013
Krtap13-2	keratin associated protein 13-2	0.013
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.013
Fcrla	Fc receptor-like A	0.013
Il10	interleukin 10	0.013
Noxo1	NADPH oxidase organizer 1	0.013
Tyms	thymidylate synthetase	0.013
Si	sucrase-isomaltase (alpha-glucosidase)	0.013
Slc28a3	solute carrier family 28 (sodium-coupled nucleoside transporter), member 3	0.013
LOC100361765	homeobox B2	0.012
LOC100362325	rCG28200-like	0.012
S100vp	S100 calcium-binding protein, ventral prostate	0.012
Vom1r101	vomeronasal 1 receptor 101	0.012
Prl7a4	prolactin family 7, subfamily a, member 4	0.012
Pdzk1	PDZ domain containing 1	0.012
Syt2	synaptotagmin II	0.012
RT1-A3	RT1 class I, locus A3	0.012
Tas2r123	taste receptor, type 2, member 123	0.012
Card6	caspase recruitment domain family, member 6	0.012
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.012
Rftn1	raftlin lipid raft linker 1	0.012
Scin	scinderin	0.012
Stat4	signal transducer and activator of transcription 4	0.012
Fam26f	family with sequence similarity 26, member F	0.012
Klrc3	killer cell lectin-like receptor subfamily C, member 3	0.012	Rat
Semg1	semenogelin I	0.012
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.012
Kcne2	potassium voltage-gated channel, Isk-related family, member 2	0.012
RGD1306474	similar to RIKEN cDNA 9530003J23	0.012
Litaf	lipopolysaccharide-induced TNF factor	0.012
Il18r1	interleukin 18 receptor 1	0.012
LOC689770	similar to osteoclast inhibitory lectin	0.012
Cd38	CD38 molecule	0.012
Il5ra	interleukin 5 receptor, alpha	0.012
Myocd	myocardin	0.012
Zfp472	zinc finger protein 472	0.011
Sept1	septin 1	0.011
Txk	TXK tyrosine kinase	0.011
Fcer1a	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	0.011
Fyb	FYN binding protein (FYB-120/130)	0.011
Clec2g	C-type lectin domain family 2, member g	0.011
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.011
RGD1563060	similar to AVLV472	0.011
LOC100361053	mCG1039741-like	0.011
Mbnl3	muscleblind-like 3 (Drosophila)	0.011
Hcls1	hematopoietic cell specific Lyn substrate 1	0.011
March1	membrane-associated ring finger (C3HC4) 1	0.011
Dok2	docking protein 2	0.011
Clec2d2	C-type lectin domain family 2 member D2	0.011
Tia1	TIA1 cytotoxic granule-associated RNA binding protein	0.011
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.011
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.011
Il27ra	interleukin 27 receptor, alpha	0.011
Atp8b4	ATPase, class I, type 8B, member 4	0.011
Fgf10	fibroblast growth factor 10	0.011
Arf6	ADP-ribosylation factor 6	0.011
Clec1a	C-type lectin domain family 1, member a	0.011	Rat
Odf4	outer dense fiber of sperm tails 4	0.011
Prg4	proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)	0.011
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.011
Sp100	SP100 nuclear antigen	0.011
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.011
Csn3	casein kappa	0.011
RGD1561226	similar to DNA segment, Chr 5, ERATO Doi 577, expressed	0.011
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.011	Rat
Arid5a	AT rich interactive domain 5A (Mrf1 like)	0.011
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.011
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.011
Usp44	ubiquitin specific peptidase 44	0.011
Dppa1	developmental pluripotency associated 1	0.010
Twf1	twinfilin, actin-binding protein, homolog 1 (Drosophila)	0.010
Atp5f1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1	0.010
Cst5	cystatin D	0.010
LOC683801	similar to zinc finger protein 740	0.010
Rgs18	regulator of G-protein signaling 18	0.010
RT1-CE10	RT1 class I, locus CE10	0.010
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.010
Gucy2g	guanylate cyclase 2G	0.010
Acadl	acyl-Coenzyme A dehydrogenase, long-chain	0.010
Olr886	olfactory receptor 886	0.010
Olr491	olfactory receptor 491	0.010
Prl8a9	prolactin family 8, subfamily a, member 9	0.010
Cd28	Cd28 molecule	0.010
Cxcl11	chemokine (C-X-C motif) ligand 11	0.010
LOC494538	ABP beta	0.010
Mmp8	matrix metallopeptidase 8	0.010
Lat2	linker for activation of T cells family, member 2	0.010
Tdh	L-threonine dehydrogenase	0.010
Ncf2	neutrophil cytosolic factor 2	0.010
RGD1564677	similar to transcription factor ONECUT2	0.010
Irf8	interferon regulatory factor 8	0.010
Uba7	ubiquitin-like modifier activating enzyme 7	0.010