IMP: Integrative Multi-species Prediction

Rattus norvegicus

31 genes annotated in rat

protein modification by small protein conjugation

A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein modification by small protein conjugation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein modification by small protein conjugation" (in gray)

Name	Description	Probability	Func Analog Organism
Dctn4	dynactin 4	0.709
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.336
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.206	Yeast
Canx	calnexin	0.097
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.095
Csnk1d	casein kinase 1, delta	0.083
Taok1	TAO kinase 1	0.078
Hsph1	heat shock 105/110 protein 1	0.077
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.071
Ppp1r2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.068
Tollip	toll interacting protein	0.068
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.068
Ubc	ubiquitin C	0.067
Zfand5	zinc finger, AN1-type domain 5	0.059
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.056
Nploc4	nuclear protein localization 4 homolog (S. cerevisiae)	0.055
Pex13	peroxisomal biogenesis factor 13	0.052
Tspyl1	TSPY-like 1	0.043
Hprt1	hypoxanthine phosphoribosyltransferase 1	0.043
Dnm1l	dynamin 1-like	0.042
Zfp364	zinc finger protein 364	0.040	Human Mouse
Adam10	ADAM metallopeptidase domain 10	0.038
Cfl2	cofilin 2, muscle	0.038
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform	0.037
MGC105560	similar to Hypothetical protein BC014729	0.036
Psmb3	proteasome (prosome, macropain) subunit, beta type 3	0.035
Vapa	VAMP (vesicle-associated membrane protein)-associated protein A	0.034
Tjp1	tight junction protein 1	0.034
Eif4h	eukaryotic translation initiation factor 4H	0.033
Prkar1a	protein kinase, cAMP-dependent, regulatory, type I, alpha	0.032
Rnf138	ring finger protein 138	0.032
Senp2	Sumo1/sentrin/SMT3 specific peptidase 2	0.032
Psmb4	proteasome (prosome, macropain) subunit, beta type 4	0.031
Eif4a2	eukaryotic translation initiation factor 4A, isoform 2	0.031
Dazap2	DAZ associated protein 2	0.030
Adrbk1	adrenergic, beta, receptor kinase 1	0.030
Tbpl1	TATA box binding protein-like 1	0.030
Troap	trophinin associated protein	0.029
Maoa	monoamine oxidase A	0.029
Rabep2	rabaptin, RAB GTPase binding effector protein 2	0.029
Actr6	ARP6 actin-related protein 6 homolog (yeast)	0.028
Mapk1	mitogen activated protein kinase 1	0.028
Rfc1	replication factor C (activator 1) 1	0.028
Rbm18	RNA binding motif protein 18	0.028
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.027
Rapgef2	Rap guanine nucleotide exchange factor (GEF) 2	0.027
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.027
Nckap1	NCK-associated protein 1	0.027
Paip1	poly(A) binding protein interacting protein 1	0.027
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.027
Atf2	activating transcription factor 2	0.027
Cops2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.027
Ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	0.027
Txnl1	thioredoxin-like 1	0.026
Spcs1	signal peptidase complex subunit 1 homolog (S. cerevisiae)	0.026
Wdr5	WD repeat domain 5	0.026
Ppp2r5e	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.026
Zranb2	zinc finger, RAN-binding domain containing 2	0.026
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.026
Magt1	magnesium transporter 1	0.025
Mprip	myosin phosphatase Rho interacting protein	0.025
Snx16	sorting nexin 16	0.024
Psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.024
Eef2	eukaryotic translation elongation factor 2	0.024
Trdmt1	tRNA aspartic acid methyltransferase 1	0.024
Trappc10	trafficking protein particle complex 10	0.024
Fundc1	FUN14 domain containing 1	0.024
Eef1e1	eukaryotic translation elongation factor 1 epsilon 1	0.023
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.023
Exoc5	exocyst complex component 5	0.023
Ppp2cb	protein phosphatase 2, catalytic subunit, beta isoform	0.023
Dnpep	aspartyl aminopeptidase	0.023
RT1-EC2	RT1 class Ib, locus EC2	0.023
Tagln3	transgelin 3	0.023
Arih1	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)	0.023	Human
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.023
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.023
Golph3	golgi phosphoprotein 3 (coat-protein)	0.023
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.022
Matk	megakaryocyte-associated tyrosine kinase	0.022
Lin7c	lin-7 homolog C (C. elegans)	0.022
Rb1	retinoblastoma 1	0.022
Hbxip	hepatitis B virus x interacting protein	0.021
Tomm70a	translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)	0.021
Ube2e3	ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog (yeast)	0.021	Mouse
Pja2	praja 2, RING-H2 motif containing	0.021	Human
Rab21	RAB21, member RAS oncogene family	0.021
Rnf2	ring finger protein 2	0.021	Human Mouse Fly
Men1	multiple endocrine neoplasia 1	0.021
Ampd1	adenosine monophosphate deaminase 1 (isoform M)	0.021
Clns1a	chloride channel, nucleotide-sensitive, 1A	0.020
Sirt2	sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)	0.020
LOC100363783	rCG53773-like	0.020
Actr1a	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.020
Fam174a	family with sequence similarity 174, member A	0.020
Cugbp1	CUG triplet repeat, RNA binding protein 1	0.019
Tpd52	tumor protein D52	0.019
LOC100366237	prefoldin subunit 4-like	0.019
Use1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	0.019
Atp6v1b2	ATPase, H transporting, lysosomal V1 subunit B2	0.019
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.019
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform	0.019
Map3k7ip1	mitogen-activated protein kinase kinase kinase 7 interacting protein 1	0.019
Tmem9b	TMEM9 domain family, member B	0.019
Tcea2	transcription elongation factor A (SII), 2	0.018
Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.018
Creb1	cAMP responsive element binding protein 1	0.018
Txnrd1	thioredoxin reductase 1	0.018
Tceal1	transcription elongation factor A (SII)-like 1	0.018
Usp9x	ubiquitin specific peptidase 9, X-linked	0.018
Ccnc	cyclin C	0.018
Med21	mediator complex subunit 21	0.018
Foxm1	forkhead box M1	0.018
Rxrb	retinoid X receptor beta	0.018
Mdfic	MyoD family inhibitor domain containing	0.017
Fxr2	fragile X mental retardation, autosomal homolog 2	0.017
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.017
Macf1	microtubule-actin crosslinking factor 1	0.017
Smad4	SMAD family member 4	0.017
Otud4	OTU domain containing 4	0.017
LOC683077	similar to praja1, RING-H2 motif containing	0.017
Pctk2	PCTAIRE protein kinase 2	0.017
Rab11a	RAB11a, member RAS oncogene family	0.017
Rnf14	ring finger protein 14	0.017
Rtcd1	RNA terminal phosphate cyclase domain 1	0.017
Gnpda2	glucosamine-6-phosphate deaminase 2	0.017
Oaz1	ornithine decarboxylase antizyme 1	0.017
Mat2b	methionine adenosyltransferase II, beta	0.017
Rnf146	ring finger protein 146	0.016	Human
Uba3	ubiquitin-like modifier activating enzyme 3	0.016	Yeast Fly
Arl6	ADP-ribosylation factor-like 6	0.016
Ubqln1	ubiquilin 1	0.016	Human
Ulk2	Unc-51 like kinase 2 (C. elegans)	0.016
Dcaf15	DDB1 and CUL4 associated factor 15	0.016
Lin7b	lin-7 homolog b (C. elegans)	0.016
Ube2z	ubiquitin-conjugating enzyme E2Z	0.016	Mouse
Ide	insulin degrading enzyme	0.016
Snap25	synaptosomal-associated protein 25	0.016
Atxn10	ataxin 10	0.016
Dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	0.016
Bap1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.016
Phax	phosphorylated adaptor for RNA export	0.016
Sbk1	SH3-binding domain kinase 1	0.015
Bat5	HLA-B associated transcript 5	0.015
Homer1	homer homolog 1 (Drosophila)	0.015
Bid	BH3 interacting domain death agonist	0.015
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.015
Pomp	proteasome maturation protein	0.015
Socs6	suppressor of cytokine signaling 6	0.015
RGD1303142	oxidative stress responsive gene	0.015
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.015
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.015
Prdm1	PR domain containing 1, with ZNF domain	0.015
Akr1a1	aldo-keto reductase family 1, member A1 (aldehyde reductase)	0.015
Tgfbr1	transforming growth factor, beta receptor 1	0.015	Human
Mtmr3	myotubularin related protein 3	0.015
Akap11	A kinase (PRKA) anchor protein 11	0.015
Slc30a1	solute carrier family 30 (zinc transporter), member 1	0.015
Gprasp1	G protein-coupled receptor associated sorting protein 1	0.015
Csnk2a2	casein kinase 2, alpha prime polypeptide	0.015
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.015
Kif18b	kinesin family member 18B	0.015
Cdv3	carnitine deficiency-associated gene expressed in ventricle 3 homolog (mouse)	0.015
Casp2	caspase 2	0.015
Pias2	protein inhibitor of activated STAT, 2	0.015	Yeast
Lyst	lysosomal trafficking regulator	0.015
Mbrl	membralin	0.015
Chordc1	cysteine and histidine-rich domain (CHORD)-containing 1	0.014
Ireb2	iron responsive element binding protein 2	0.014
Dynlrb1	dynein light chain roadblock-type 1	0.014
Nap1l3	nucleosome assembly protein 1-like 3	0.014
Itgad	integrin, alpha D	0.014
Lrrc59	leucine rich repeat containing 59	0.014
Ppid	peptidylprolyl isomerase D (cyclophilin D)	0.014
Racgap1	Rac GTPase-activating protein 1	0.014
Nptn	neuroplastin	0.014
Ensa	endosulfine alpha	0.014
Nat12	N-acetyltransferase 12 (GCN5-related, putative)	0.014
Rlim	ring finger protein, LIM domain interacting	0.014
Rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.014
Mea1	male-enhanced antigen 1	0.014
Pdcd4	programmed cell death 4	0.014
Ube2d2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.014
LOC100361944	hypothetical protein LOC100361944	0.014
Cherp	calcium homeostasis endoplasmic reticulum protein	0.014
Gmfb	glia maturation factor, beta	0.014
Egr2	early growth response 2	0.014
Ate1	arginyltransferase 1	0.014
Cmya5	cardiomyopathy associated 5	0.014
Trim28	tripartite motif-containing 28	0.014	Human
LOC690217	similar to B0511.12	0.014
Cd5	Cd5 molecule	0.014
Tor1aip2	torsin A interacting protein 2	0.013
Ccdc97	coiled-coil domain containing 97	0.013
Ppp1r10	protein phosphatase 1, regulatory subunit 10	0.013
Btbd1	BTB (POZ) domain containing 1	0.013
Fiz1	FLT3-interacting zinc finger 1	0.013
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.013
Pcgf5	polycomb group ring finger 5	0.013
Trim54	tripartite motif-containing 54	0.013	Rat
Cltc	clathrin, heavy chain (Hc)	0.013
Mtus1	mitochondrial tumor suppressor 1	0.013
Pkn2	protein kinase N2	0.013
Qars	glutaminyl-tRNA synthetase	0.013
Tm2d1	TM2 domain containing 1	0.013
Pias4	protein inhibitor of activated STAT, 4	0.013	Human Yeast
Bard1	BRCA1 associated RING domain 1	0.013	Human
Cno	cappuccino homolog (mouse)	0.013
Lig3	ligase III, DNA, ATP-dependent	0.013
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.013
Cdc42	cell division cycle 42 (GTP binding protein)	0.013
Usp14	ubiquitin specific peptidase 14	0.013
Ap2b1	adaptor-related protein complex 2, beta 1 subunit	0.013
Cenpi	centromere protein I	0.013
RGD1308026	similar to 2310047B19Rik protein	0.013
Metap1	methionyl aminopeptidase 1	0.013
Fcnb	ficolin B	0.013
Parp14	poly (ADP-ribose) polymerase family, member 14	0.013
Xpo6	exportin 6	0.013
Usp4	ubiquitin specific peptidase 4 (proto-oncogene)	0.013
Apeh	N-acylaminoacyl-peptide hydrolase	0.013
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.013
Camk2g	calcium/calmodulin-dependent protein kinase II gamma	0.013
Pdcd10	programmed cell death 10	0.013
Map2k4	mitogen activated protein kinase kinase 4	0.013
Usp19	ubiquitin specific peptidase 19	0.012
Tpp2	tripeptidyl peptidase II	0.012
Tulp2	tubby-like protein 2	0.012
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.012
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.012
Hsp90b1	heat shock protein 90, beta, member 1	0.012
Cog8	component of oligomeric golgi complex 8	0.012
Map2k1	mitogen activated protein kinase kinase 1	0.012
Pcyt1b	phosphate cytidylyltransferase 1, choline, beta	0.012
Orc4l	origin recognition complex, subunit 4-like (yeast)	0.012
Apob	apolipoprotein B	0.012
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.012
Pten	phosphatase and tensin homolog	0.012	Human
Abtb1	ankyrin repeat and BTB (POZ) domain containing 1	0.012
Dph3	DPH3, KTI11 homolog (S. cerevisiae)	0.012
Foxj3	forkhead box J3	0.012
Zkscan1	zinc finger with KRAB and SCAN domains 1	0.012
Apex1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.012
Shank2	SH3 and multiple ankyrin repeat domains 2	0.012
Axin1	axin 1	0.012
Nek1	NIMA (never in mitosis gene a)-related kinase 1	0.012
Tcf12	transcription factor 12	0.012
Rybp	RING1 and YY1 binding protein	0.012
Raf1	v-raf-leukemia viral oncogene 1	0.012
Dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36	0.012
RGD1309102	similar to TRS85 homolog	0.012
Stx12	syntaxin 12	0.012
Psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.012
Klhl17	kelch-like 17 (Drosophila)	0.012
Epha2	Eph receptor A2	0.012
Mdm2	Mdm2 p53 binding protein homolog (mouse)	0.012
Sqstm1	sequestosome 1	0.012
Trappc2	trafficking protein particle complex 2	0.012
LOC100361445	mCG7602-like	0.012
Klf9	Kruppel-like factor 9	0.012
Tmem93	transmembrane protein 93	0.012
Ublcp1	ubiquitin-like domain containing CTD phosphatase 1	0.011
Rabep1	rabaptin, RAB GTPase binding effector protein 1	0.011
Cul3	cullin 3	0.011	Human
Slmap	sarcolemma associated protein	0.011
Csnk1a1	casein kinase 1, alpha 1	0.011
Znrd1	zinc ribbon domain containing, 1	0.011
Tle4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	0.011
Golga7	golgi autoantigen, golgin subfamily a, 7	0.011
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.011
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.011
Pi4k2b	phosphatidylinositol 4-kinase type 2 beta	0.011
Csda	cold shock domain protein A	0.011
Zc3h6	zinc finger CCCH type containing 6	0.011
Gak	cyclin G associated kinase	0.011
Usp47	ubiquitin specific peptidase 47	0.011
Fos	FBJ osteosarcoma oncogene	0.011
Calm2	calmodulin 2	0.011
Acacb	acetyl-Coenzyme A carboxylase beta	0.011
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.011	Human Mouse
MGC95208	similar to 4930453N24Rik protein	0.011
Map3k7ip2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	0.011
Hdac2	histone deacetylase 2	0.011
Clasp2	cytoplasmic linker associated protein 2	0.011
Ubr5	ubiquitin protein ligase E3 component n-recognin 5	0.011
Ckmt1	creatine kinase, mitochondrial 1	0.011
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.011
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.011
Gipc3	GIPC PDZ domain containing family, member 3	0.011
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.011
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.011
Camsap1	calmodulin regulated spectrin-associated protein 1	0.011
Mtvr2	mammary tumor virus receptor 2	0.011
Top2a	topoisomerase (DNA) II alpha	0.011
LOC689443	similar to TBC1 domain family member 22A	0.011
Defb1	defensin beta 1	0.011
Tbca	tubulin folding cofactor A	0.011
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.011
Cyb5b	cytochrome b5 type B (outer mitochondrial membrane)	0.011
Map3k1	mitogen activated protein kinase kinase kinase 1	0.011
Arih2	ariadne homolog 2 (Drosophila)	0.011	Human
Fam103a1	family with sequence similarity 103, member A1	0.011
Cd247	Cd247 molecule	0.011
Hace1	HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1	0.011	Human
Ppm1d	protein phosphatase 1D magnesium-dependent, delta isoform	0.011
Yaf2	YY1 associated factor 2	0.011
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.011
Lysmd2	LysM, putative peptidoglycan-binding, domain containing 2	0.011
Selk	selenoprotein K	0.011
Scnm1	sodium channel modifier 1	0.011
Trio	triple functional domain (PTPRF interacting)	0.011
Pfn2	profilin 2	0.011
Ccdc117	coiled-coil domain containing 117	0.011
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.011
Lrrc41	leucine rich repeat containing 41	0.011
Csnk1g3	casein kinase 1, gamma 3	0.011
Snca	synuclein, alpha (non A4 component of amyloid precursor)	0.011
Ier2	immediate early response 2	0.011
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.011
Rbm4b	RNA binding motif protein 4B	0.011
LOC100192313	hypothetical protein LOC100192313	0.011
Slc45a3	solute carrier family 45, member 3	0.010
Crebl2	cAMP responsive element binding protein-like 2	0.010
Dusp2	dual specificity phosphatase 2	0.010
Fyttd1	forty-two-three domain containing 1	0.010
Trove2	TROVE domain family, member 2	0.010
Nub1	negative regulator of ubiquitin-like proteins 1	0.010
Ubap1	ubiquitin-associated protein 1	0.010
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.010
Zc3h15	zinc finger CCCH-type containing 15	0.010
Ccl20	chemokine (C-C motif) ligand 20	0.010
Sos1	Son of sevenless homolog 1 (Drosophila)	0.010
Brms1l	breast cancer metastasis-suppressor 1-like	0.010
Lad1	ladinin 1	0.010
Txn1	thioredoxin 1	0.010
Spag5	sperm associated antigen 5	0.010
Wdr37	WD repeat domain 37	0.010
Camk2b	calcium/calmodulin-dependent protein kinase II beta	0.010
Luzp1	leucine zipper protein 1	0.010
Ucn2	urocortin 2	0.010
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.010
Wtap	Wilms tumor 1 associated protein	0.010
Plekhj1	pleckstrin homology domain containing, family J member 1	0.010
Bcl10	B-cell CLL/lymphoma 10	0.010