Process View
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitotic dna damage checkpoint"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Gpi | glucose phosphate isomerase | 0.114 | ||
Pkm2 | pyruvate kinase, muscle | 0.104 | ||
Slc25a4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 0.079 | ||
Dnaja2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.059 | ||
Ldha | lactate dehydrogenase A | 0.054 | ||
Gapdh | glyceraldehyde-3-phosphate dehydrogenase | 0.051 | ||
Zfand5 | zinc finger, AN1-type domain 5 | 0.048 | ||
Top2a | topoisomerase (DNA) II alpha | 0.040 | ||
Bnip3l | BCL2/adenovirus E1B interacting protein 3-like | 0.032 | ||
Cdk4 | cyclin-dependent kinase 4 | 0.029 | ||
Zfand6 | zinc finger, AN1-type domain 6 | 0.029 | ||
Tcp11l2 | t-complex 11 (mouse) like 2 | 0.028 | ||
Ptbp1 | polypyrimidine tract binding protein 1 | 0.027 | ||
Stxbp3 | syntaxin binding protein 3 | 0.026 | ||
Pcmtd2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.026 | ||
Tnks2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.025 | ||
Rpa2 | replication protein A2 | 0.025 | ||
Cdc42 | cell division cycle 42 (GTP binding protein) | 0.024 | ||
Spc25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.022 | ||
Cdca7 | cell division cycle associated 7 | 0.022 | ||
Mcm6 | minichromosome maintenance complex component 6 | 0.022 | ||
Acyp2 | acylphosphatase 2, muscle type | 0.022 | ||
Tpi1 | triosephosphate isomerase 1 | 0.020 | ||
Gnas | GNAS complex locus | 0.019 | ||
Mcm3 | minichromosome maintenance complex component 3 | 0.019 | ||
Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.019 | ||
Rbbp7 | retinoblastoma binding protein 7 | 0.018 | ||
Usp9x | ubiquitin specific peptidase 9, X-linked | 0.017 | ||
Capza2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.017 | ||
Cops2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.016 | ||
Pgk1 | phosphoglycerate kinase 1 | 0.016 | ||
Ccnb1 | cyclin B1 | 0.016 | ||
Mcm5 | minichromosome maintenance complex component 5 | 0.016 | ||
Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.016 | ||
Cdca4 | cell division cycle associated 4 | 0.015 | ||
Eno1 | enolase 1, (alpha) | 0.015 | ||
Ppp1r2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.015 | ||
Ube2c | ubiquitin-conjugating enzyme E2C | 0.015 | ||
Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.015 | ||
Pcmt1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 | 0.014 | ||
Brms1l | breast cancer metastasis-suppressor 1-like | 0.014 | ||
Metap2 | methionyl aminopeptidase 2 | 0.014 | ||
Serinc1 | serine incorporator 1 | 0.014 | ||
Eif4a2 | eukaryotic translation initiation factor 4A, isoform 2 | 0.014 | ||
Cul3 | cullin 3 | 0.014 | ||
Pdp1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.014 | ||
Melk | maternal embryonic leucine zipper kinase | 0.013 | ||
Bnip3 | BCL2/adenovirus E1B interacting protein 3 | 0.013 | ||
Clns1a | chloride channel, nucleotide-sensitive, 1A | 0.013 | ||
Ns5atp9 | NS5A (hepatitis C virus) transactivated protein 9 | 0.013 | ||
Ube2a | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.013 | ||
Cbfb | core-binding factor, beta subunit | 0.013 | ||
Ptp4a1 | protein tyrosine phosphatase type IVA, member 1 | 0.013 | ||
Ccnb2 | cyclin B2 | 0.013 | ||
Paip2 | poly(A) binding protein interacting protein 2 | 0.013 | ||
Lsm14a | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.013 | ||
Gabarapl2 | GABA(A) receptor-associated protein like 2 | 0.012 | ||
Psmd2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.012 | ||
Gcs1 | glucosidase 1 | 0.012 | ||
Mdm2 | Mdm2 p53 binding protein homolog (mouse) | 0.012 | ||
Ppm1b | protein phosphatase 1B, magnesium dependent, beta isoform | 0.012 | ||
Tob1 | transducer of ErbB-2.1 | 0.012 | ||
Zhx1 | zinc fingers and homeoboxes 1 | 0.012 | ||
Klhl9 | kelch-like 9 (Drosophila) | 0.012 | ||
Adrbk1 | adrenergic, beta, receptor kinase 1 | 0.012 | ||
Rbm18 | RNA binding motif protein 18 | 0.012 | ||
Mcm2 | minichromosome maintenance complex component 2 | 0.012 | ||
Mxi1 | MAX interactor 1 | 0.012 | ||
Racgap1 | Rac GTPase-activating protein 1 | 0.012 | ||
Sdc1 | syndecan 1 | 0.012 | ||
Stag2 | stromal antigen 2 | 0.012 | ||
Ccng1 | cyclin G1 | 0.012 | ||
Blmh | bleomycin hydrolase | 0.012 | ||
Supt16h | suppressor of Ty 16 homolog (S. cerevisiae) | 0.011 | ||
Fam21c | family with sequence similarity 21, member C | 0.011 | ||
Kifc1 | kinesin family member C1 | 0.011 | ||
Ckb | creatine kinase, brain | 0.011 | ||
Pttg1 | pituitary tumor-transforming 1 | 0.011 | ||
Sh3yl1 | SH3 domain containing, Ysc84-like 1 (S. cerevisiae) | 0.011 | ||
Tp53 | tumor protein p53 | 0.011 | Human | |
Mapk6 | mitogen-activated protein kinase 6 | 0.011 | ||
Pdcd4 | programmed cell death 4 | 0.011 | ||
Sesn1 | sestrin 1 | 0.011 | ||
Hmgb2 | high mobility group box 2 | 0.011 | ||
Adam10 | ADAM metallopeptidase domain 10 | 0.011 | ||
Tle4 | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 0.010 | ||
Prkd3 | protein kinase D3 | 0.010 | ||
Ube2g1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.010 | ||
Gnb2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.010 | ||
Fcho2 | FCH domain only 2 | 0.010 | ||
Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.010 | ||
Mat2b | methionine adenosyltransferase II, beta | 0.010 | ||
Adar | adenosine deaminase, RNA-specific | 0.010 | ||
Brp16 | brain protein 16 | 0.010 | ||
Ccdc132 | coiled-coil domain containing 132 | 0.010 | ||
Leprot | leptin receptor overlapping transcript | 0.010 | ||
Smad2 | SMAD family member 2 | 0.010 | ||
Tmco3 | transmembrane and coiled-coil domains 3 | 0.010 |