IMP
Process View
regulation of interleukin 6 production
Any process that modulates the frequency, rate, or extent of interleukin-6 production.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 6 production"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.183 | ||
| Hspa5 | heat shock protein 5 | 0.167 | ||
| Gja6 | gap junction protein, alpha 6 | 0.145 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.136 | ||
| Gzmk | granzyme K | 0.119 | ||
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.110 | ||
| Casp12 | caspase 12 | 0.091 | ||
| LOC24906 | RoBo-1 | 0.090 | ||
| Mmp12 | matrix metallopeptidase 12 | 0.085 | ||
| Fosl1 | fos-like antigen 1 | 0.078 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.077 | ||
| Npffr2 | neuropeptide FF receptor 2 | 0.073 | ||
| Il1b | interleukin 1 beta | 0.072 | ||
| Acrv1 | acrosomal vesicle protein 1 | 0.063 | ||
| Junb | jun B proto-oncogene | 0.061 | ||
| Sox17 | SRY (sex determining region Y)-box 17 | 0.061 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.059 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.054 | ||
| Faslg | Fas ligand (TNF superfamily, member 6) | 0.053 | ||
| Slc7a3 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 | 0.051 | ||
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.049 | ||
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.047 | ||
| Il9r | interleukin 9 receptor | 0.043 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.041 | ||
| Errfi1 | ERBB receptor feedback inhibitor 1 | 0.038 | ||
| Calhm2 | calcium homeostasis modulator 2 | 0.037 | ||
| Cxcl6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.037 | ||
| Hspa8 | heat shock protein 8 | 0.037 | ||
| Avp | arginine vasopressin | 0.036 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.036 | ||
| Pdia6 | protein disulfide isomerase family A, member 6 | 0.035 | ||
| Zfp36 | zinc finger protein 36 | 0.034 | ||
| Il2rg | interleukin 2 receptor, gamma | 0.034 | ||
| Adora2a | adenosine A2a receptor | 0.034 | ||
| Cfp | complement factor properdin | 0.033 | ||
| Ltbr | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.033 | ||
| C5ar1 | complement component 5a receptor 1 | 0.033 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.031 | ||
| Il6 | interleukin 6 | 0.031 | ||
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.030 | ||
| Arhgap4 | Rho GTPase activating protein 4 | 0.030 | ||
| Shc1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.030 | ||
| Prl8a7 | prolactin family 8, subfamily a, member 7 | 0.029 | ||
| Tnni3 | troponin I type 3 (cardiac) | 0.029 | ||
| Rhbdl1 | rhomboid, veinlet-like 1 (Drosophila) | 0.029 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.028 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.028 | ||
| Syt8 | synaptotagmin VIII | 0.027 | ||
| Ghr | growth hormone receptor | 0.027 | ||
| Grm6 | glutamate receptor, metabotropic 6 | 0.027 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.027 | ||
| A2m | alpha-2-macroglobulin | 0.026 | ||
| Ciita | class II, major histocompatibility complex, transactivator | 0.026 | ||
| Rps6ka1 | ribosomal protein S6 kinase polypeptide 1 | 0.026 | ||
| Sh2b3 | SH2B adaptor protein 3 | 0.026 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.026 | ||
| Slc22a7 | solute carrier family 22 (organic anion transporter), member 7 | 0.026 | ||
| Hsp90aa1 | heat shock protein 90, alpha (cytosolic), class A member 1 | 0.025 | ||
| Lpl | lipoprotein lipase | 0.025 | ||
| Ptprz1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.024 | ||
| Cx3cr1 | chemokine (C-X3-C motif) receptor 1 | 0.024 | ||
| Pax6 | paired box 6 | 0.024 | ||
| Alox5 | arachidonate 5-lipoxygenase | 0.024 | ||
| Ifna1 | interferon-alpha 1 | 0.023 | ||
| Itgam | integrin, alpha M | 0.023 | ||
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.023 | ||
| Cyp27b1 | cytochrome P450, family 27, subfamily b, polypeptide 1 | 0.023 | ||
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.022 | ||
| Tlr4 | toll-like receptor 4 | 0.022 | Human Mouse | |
| Jun | Jun oncogene | 0.022 | ||
| Ptger2 | prostaglandin E receptor 2 (subtype EP2) | 0.022 | ||
| Hspe1 | heat shock protein 1 (chaperonin 10) | 0.021 | ||
| Mcpt3 | mast cell peptidase 3 | 0.021 | ||
| Slc14a2 | solute carrier family 14 (urea transporter), member 2 | 0.021 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.020 | ||
| Pip | prolactin induced protein | 0.020 | ||
| Fgb | fibrinogen beta chain | 0.020 | ||
| Gm2a | GM2 ganglioside activator | 0.020 | ||
| Edn1 | endothelin 1 | 0.020 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.019 | Mouse | |
| C1qtnf6 | C1q and tumor necrosis factor related protein 6 | 0.019 | ||
| Nradd | neurotrophin receptor associated death domain | 0.019 | ||
| RGD1309079 | similar to Ab2-095 | 0.019 | ||
| Ece1 | endothelin converting enzyme 1 | 0.019 | ||
| RGD1561143 | similar to cell surface receptor FDFACT | 0.019 | ||
| Gfpt1 | glutamine fructose-6-phosphate transaminase 1 | 0.018 | ||
| Chrna7 | cholinergic receptor, nicotinic, alpha 7 | 0.018 | ||
| Mmp8 | matrix metallopeptidase 8 | 0.018 | ||
| LOC690358 | similar to PR domain containing 11 | 0.018 | ||
| Olr416 | olfactory receptor 416 | 0.018 | ||
| Mapk14 | mitogen activated protein kinase 14 | 0.018 | ||
| LOC681996 | similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 1 | 0.018 | ||
| Epor | erythropoietin receptor | 0.017 | ||
| Ptafr | platelet-activating factor receptor | 0.017 | ||
| Serpina3n | serine (or cysteine) peptidase inhibitor, clade A, member 3N | 0.017 | ||
| RGD1305793 | similar to hypothetical protein FLJ20154 | 0.016 | ||
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.016 | ||
| Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 | 0.016 | ||
| Oprk1 | opioid receptor, kappa 1 | 0.016 | ||
| Adora2b | adenosine A2B receptor | 0.015 | Mouse | |
| Cd38 | CD38 molecule | 0.015 | ||
| Cmklr1 | chemokine-like receptor 1 | 0.015 | ||
| Ralgds | ral guanine nucleotide dissociation stimulator | 0.015 | ||
| Tnfsf4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.015 | Mouse | |
| Ncan | neurocan | 0.015 | ||
| Dpep1 | dipeptidase 1 (renal) | 0.015 | ||
| Cd247 | Cd247 molecule | 0.015 | ||
| RT1-Ba | RT1 class II, locus Ba | 0.015 | ||
| Kcnh7 | potassium voltage-gated channel, subfamily H (eag-related), member 7 | 0.014 | ||
| Psp | parotid secretory protein | 0.014 | ||
| Mov10 | Moloney leukemia virus 10 | 0.014 | ||
| Hsph1 | heat shock 105/110 protein 1 | 0.014 | ||
| Cd8b | CD8b molecule | 0.014 | ||
| C3ar1 | complement component 3a receptor 1 | 0.014 | ||
| Xdh | xanthine dehydrogenase | 0.014 | ||
| LOC290595 | hypothetical gene supported by AF152002 | 0.014 | ||
| Chrnb3 | cholinergic receptor, nicotinic, beta 3 | 0.014 | ||
| Defb1 | defensin beta 1 | 0.014 | ||
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.014 | ||
| Gch1 | GTP cyclohydrolase 1 | 0.014 | ||
| Slc25a5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.014 | ||
| Nmbr | neuromedin B receptor | 0.013 | ||
| Prol1 | proline rich, lacrimal 1 | 0.013 | ||
| Testin | testin gene | 0.013 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.013 | ||
| Plscr1 | phospholipid scramblase 1 | 0.013 | ||
| Pde1c | phosphodiesterase 1C | 0.013 | ||
| Kcnk9 | potassium channel, subfamily K, member 9 | 0.013 | ||
| Mobp | myelin-associated oligodendrocyte basic protein | 0.013 | ||
| Zfp36l1 | zinc finger protein 36, C3H type-like 1 | 0.013 | ||
| Slc24a6 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 | 0.013 | ||
| Olr857 | olfactory receptor 857 | 0.012 | ||
| Kcnh8 | potassium voltage-gated channel, subfamily H (eag-related), member 8 | 0.012 | ||
| Fam113b | family with sequence similarity 113, member B | 0.012 | ||
| Fgf16 | fibroblast growth factor 16 | 0.012 | ||
| Als2cl | ALS2 C-terminal like | 0.012 | ||
| Slc5a2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 0.012 | ||
| Smad1 | SMAD family member 1 | 0.012 | ||
| Nrarp | Notch-regulated ankyrin repeat protein | 0.012 | ||
| Lcn2 | lipocalin 2 | 0.012 | ||
| Mapk4 | mitogen-activated protein kinase 4 | 0.012 | ||
| Amelx | amelogenin X chromosome | 0.012 | ||
| Ager | advanced glycosylation end product-specific receptor | 0.012 | ||
| Serpine1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.012 | ||
| Akr1c14 | aldo-keto reductase family 1, member C14 | 0.012 | ||
| Itpkb | inositol 1,4,5-trisphosphate 3-kinase B | 0.012 | ||
| Steap4 | STEAP family member 4 | 0.011 | ||
| Olr1278 | olfactory receptor 1278 | 0.011 | ||
| RGD1309543 | similar to 2310014H01Rik protein | 0.011 | ||
| Hand1 | heart and neural crest derivatives expressed 1 | 0.011 | ||
| Il1a | interleukin 1 alpha | 0.011 | ||
| Hoxa2 | homeo box A2 | 0.011 | ||
| Gltp | glycolipid transfer protein | 0.011 | ||
| Il2rb | interleukin 2 receptor, beta | 0.011 | ||
| Cycs | cytochrome c, somatic | 0.011 | ||
| Psg19 | pregnancy specific glycoprotein 19 | 0.011 | ||
| Rftn2 | raftlin family member 2 | 0.011 | ||
| Lta | lymphotoxin alpha (TNF superfamily, member 1) | 0.011 | ||
| Dem1 | defects in morphology 1 homolog (S. cerevisiae) | 0.011 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.011 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.010 | ||
| Ptpn1 | protein tyrosine phosphatase, non-receptor type 1 | 0.010 | ||
| Ucp1 | uncoupling protein 1 (mitochondrial, proton carrier) | 0.010 | ||
| Zp1 | zona pellucida glycoprotein 1 (sperm receptor) | 0.010 | ||
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.010 | ||
| Tmem45b | transmembrane protein 45b | 0.010 | ||
| Tbxas1 | thromboxane A synthase 1, platelet | 0.010 | ||
| Slc6a1 | solute carrier family 6 (neurotransmitter transporter, GABA), member 1 | 0.010 | ||
| Rrbp1 | ribosome binding protein 1 | 0.010 | ||
| Upk3bl | uroplakin 3B-like | 0.010 | ||
| Gnb4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | 0.010 | ||
| Ier3 | immediate early response 3 | 0.010 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.010 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.010 | ||
| Mep1a | meprin 1 alpha | 0.010 | ||
| Gabrr1 | gamma-aminobutyric acid (GABA) receptor, rho 1 | 0.010 | ||
| LOC100365152 | adaptor-related protein complex 1, gamma 2 subunit-like | 0.010 |