IMP: Integrative Multi-species Prediction

Rattus norvegicus

29 genes annotated in rat

Multi-species View

positive regulation of developmental growth

GO:0048639

Any process that activates, maintains or increases the rate of developmental growth.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of developmental growth"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of developmental growth" (in gray)

Name	Description	Probability	Func Analog Organism
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.057
Dlg4	discs, large homolog 4 (Drosophila)	0.052	Fly
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.045
Phkg1	phosphorylase kinase, gamma 1	0.042
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.042
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.035	Fly
Otx1	orthodenticle homeobox 1	0.034
Chrng	cholinergic receptor, nicotinic, gamma	0.032
Syt6	synaptotagmin VI	0.031
Eef2	eukaryotic translation elongation factor 2	0.030
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.027
Map2	microtubule-associated protein 2	0.027
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.025
Clca4	chloride channel accessory 4	0.025
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.025	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.024
Smad7	SMAD family member 7	0.024
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.022
Prkca	protein kinase C, alpha	0.022
Nfasc	neurofascin	0.022
Prrx1	paired related homeobox 1	0.022
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.021	Worm
Cebpe	CCAAT/enhancer binding protein (C/EBP), epsilon	0.021
Ube2c	ubiquitin-conjugating enzyme E2C	0.021
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.021
Synpo	synaptopodin	0.021
Myt1l	myelin transcription factor 1-like	0.020
Arnt	aryl hydrocarbon receptor nuclear translocator	0.020
Cdkn3	cyclin-dependent kinase inhibitor 3	0.020
Olr287	olfactory receptor 287	0.020
Cast	calpastatin	0.020
Plcg1	phospholipase C, gamma 1	0.020
Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.020
Atxn1	ataxin 1	0.020
Cga	glycoprotein hormones, alpha polypeptide	0.019
Prp15	proline-rich protein 15	0.019
Srd5a2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	0.019
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.019
Smad3	SMAD family member 3	0.018
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.018
Kalrn	kalirin, RhoGEF kinase	0.018	Worm Fly
Musk	muscle, skeletal, receptor tyrosine kinase	0.018
Gja3	gap junction protein, alpha 3	0.018
Scn8a	sodium channel, voltage gated, type VIII, alpha subunit	0.018
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.018
Tf	transferrin	0.017
Prl8a2	prolactin family 8, subfamily a, member 2	0.017
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.017
Kap	kidney androgen regulated protein	0.017
Gdf11	growth differentiation factor 11	0.017
Stx2	syntaxin 2	0.017
Nrxn3	neurexin 3	0.017
Gria2	glutamate receptor, ionotropic, AMPA 2	0.017
Chmp1a	chromatin modifying protein 1A	0.017
Kcnh5	potassium voltage-gated channel, subfamily H (eag-related), member 5	0.017
Calcrl	calcitonin receptor-like	0.016
Robo1	roundabout homolog 1 (Drosophila)	0.016
Epn2	epsin 2	0.016
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.016
Syngap1	synaptic Ras GTPase activating protein 1 homolog (rat)	0.016
Myo1c	myosin IC	0.016
Sirpa	signal-regulatory protein alpha	0.015
Tcf12	transcription factor 12	0.015
Ptafr	platelet-activating factor receptor	0.015
Chrm1	cholinergic receptor, muscarinic 1	0.015
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.015
Lbr	lamin B receptor	0.015
Fabp6	fatty acid binding protein 6, ileal	0.015
Hspb2	heat shock protein beta 2	0.015
Errfi1	ERBB receptor feedback inhibitor 1	0.015
Slc18a3	solute carrier family 18 (vesicular acetylcholine), member 3	0.015
Lin7c	lin-7 homolog C (C. elegans)	0.015
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.015
Ppp1r3b	protein phosphatase 1, regulatory (inhibitor) subunit 3B	0.014
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.014
Egr3	early growth response 3	0.014
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.014
Olr857	olfactory receptor 857	0.014
Pex5l	peroxisomal biogenesis factor 5-like	0.014
Clcn4-2	chloride channel 4-2	0.014
Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2	0.014
Fgfr2	fibroblast growth factor receptor 2	0.014	Mouse
Drd3	dopamine receptor D3	0.014
Bcl2	B-cell CLL/lymphoma 2	0.014	Mouse
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.014
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.013
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.013
Fgf14	fibroblast growth factor 14	0.013	Rat
Ptgfrn	prostaglandin F2 receptor negative regulator	0.013
Slc8a3	solute carrier family 8 (sodium/calcium exchanger), member 3	0.013
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.013
Ednra	endothelin receptor type A	0.013
Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.013
Top1	topoisomerase (DNA) I	0.013
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.013
Tef	thyrotrophic embryonic factor	0.013
Ptch1	patched homolog 1 (Drosophila)	0.013
Klc1	kinesin light chain 1	0.013
Syn1	synapsin I	0.013
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.013
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.013
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.013
C1r	complement component 1, r subcomponent	0.012
Rgs14	regulator of G-protein signaling 14	0.012
Spag11b	sperm associated antigen 11B	0.012
Nos1	nitric oxide synthase 1, neuronal	0.012
Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	0.012
Efna5	ephrin A5	0.012
LOC60591	calcium-activated potassium channel beta subunit	0.012
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.012
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)	0.012
Chrnb1	cholinergic receptor, nicotinic, beta 1 (muscle)	0.012
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.012
Mprip	myosin phosphatase Rho interacting protein	0.012
Cfb	complement factor B	0.012
Kl	Klotho	0.012
Pdc	phosducin	0.012
Sox4	SRY (sex determining region Y)-box 4	0.012
Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.012
Tnni2	troponin I type 2 (skeletal, fast)	0.012
Aqp4	aquaporin 4	0.012
Map6	microtubule-associated protein 6	0.012
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.012
Pdyn	prodynorphin	0.012
Olr226	olfactory receptor 226	0.012
Hpcal4	hippocalcin-like 4	0.012
Dchs1	dachsous 1 (Drosophila)	0.012
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.012
F13a1	coagulation factor XIII, A1 polypeptide	0.012
Foxo3	forkhead box O3	0.012
Lims1	LIM and senescent cell antigen-like domains 1	0.012
Cdc42	cell division cycle 42 (GTP binding protein)	0.012
Cks2	CDC28 protein kinase regulatory subunit 2	0.012
Dck	deoxycytidine kinase	0.011
C2	complement component 2	0.011
Creb1	cAMP responsive element binding protein 1	0.011	Mouse
Aqp2	aquaporin 2 (collecting duct)	0.011
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
Clcn7	chloride channel 7	0.011
Fnbp1	formin binding protein 1	0.011
Tcof1	Treacher Collins-Franceschetti syndrome 1 homolog (human)	0.011
Gucy2f	guanylate cyclase 2F	0.011
Mark2	MAP/microtubule affinity-regulating kinase 2	0.011
Mylk2	myosin light chain kinase 2	0.011
Mcpt1	mast cell protease 1	0.011
RGD1562618	similar to RIKEN cDNA 6030419C18 gene	0.011
Pdgfb	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.011
Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.011
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.011	Fly
Txnrd1	thioredoxin reductase 1	0.011
Tpc1808	tropic 1808	0.011
Alkbh5	alkB, alkylation repair homolog 5 (E. coli)	0.011
Nefl	neurofilament, light polypeptide	0.011
Ylpm1	YLP motif containing 1	0.011
Unc5a	unc-5 homolog A (C. elegans)	0.011	Worm
Oprd1	opioid receptor, delta 1	0.011
Cfp	complement factor properdin	0.011
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.011
N5	DNA binding protein N5	0.011
Nsfl1c	NSFL1 (p97) cofactor (p47)	0.011
Adcy5	adenylate cyclase 5	0.011
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.011
Cryga	crystallin, gamma A	0.011
Il5	interleukin 5	0.011
Cadm1	cell adhesion molecule 1	0.011
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.011
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.011
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.010	Mouse
Acvr1c	activin A receptor, type IC	0.010	Rat Worm
Agtr1a	angiotensin II receptor, type 1a	0.010
Clrn3	clarin 3	0.010
Grm7	glutamate receptor, metabotropic 7	0.010
Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	0.010
Psmd2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.010
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.010	Worm
Drd2	dopamine receptor D2	0.010	Mouse
Erc1	ELKS/RAB6-interacting/CAST family member 1	0.010
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.010
Fgf10	fibroblast growth factor 10	0.010	Rat
Rph3a	rabphilin 3A	0.010
Myo9a	myosin IXA	0.010
Rgs8	regulator of G-protein signaling 8	0.010
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.010
Met	met proto-oncogene	0.010
Rgs9	regulator of G-protein signaling 9	0.010
Isl1	ISL LIM homeobox 1	0.010
Tacr3	tachykinin receptor 3	0.010