IMP
Process View
chromosome separation
The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "chromosome separation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Foxm1 | forkhead box M1 | 0.073 | ||
| Ect2 | epithelial cell transforming sequence 2 oncogene | 0.047 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.046 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.044 | ||
| Spc25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.041 | ||
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.040 | ||
| Spag5 | sperm associated antigen 5 | 0.040 | ||
| Ccnb1 | cyclin B1 | 0.039 | ||
| LOC100310874 | antisense RNA overlapping MCH | 0.037 | ||
| Lbr | lamin B receptor | 0.032 | ||
| Kif2c | kinesin family member 2C | 0.028 | ||
| Litaf | lipopolysaccharide-induced TNF factor | 0.026 | ||
| Znf76 | zinc finger protein 76 (expressed in testis) | 0.025 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.025 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.025 | ||
| Lrch4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | 0.024 | ||
| LOC689399 | hypothetical protein LOC689399 | 0.024 | ||
| Syncrip | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.024 | ||
| Arfip1 | ADP-ribosylation factor interacting protein 1 | 0.023 | ||
| Pttg1 | pituitary tumor-transforming 1 | 0.023 | ||
| Ppp4r2 | protein phosphatase 4, regulatory subunit 2 | 0.023 | ||
| Rpl10a | ribosomal protein L10A | 0.023 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.023 | Yeast Worm Fly | |
| E2f1 | E2F transcription factor 1 | 0.022 | ||
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.022 | ||
| Nxph4 | neurexophilin 4 | 0.022 | ||
| Rps15a | ribosomal protein S15a | 0.021 | ||
| Slain2 | SLAIN motif family, member 2 | 0.021 | ||
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.021 | ||
| Pds5a | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) | 0.021 | ||
| Ppm1b | protein phosphatase 1B, magnesium dependent, beta isoform | 0.021 | ||
| Cops2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.020 | ||
| Tpm4 | tropomyosin 4 | 0.020 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.020 | Human Yeast | |
| Ctnnd2 | catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) | 0.020 | ||
| Ttk | Ttk protein kinase | 0.020 | ||
| Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 0.020 | ||
| Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.019 | ||
| Rpl7a | ribosomal protein L7a | 0.019 | ||
| Kifc1 | kinesin family member C1 | 0.019 | ||
| Cdca3 | cell division cycle associated 3 | 0.018 | ||
| Mcpt4 | mast cell protease 4 | 0.018 | ||
| Melk | maternal embryonic leucine zipper kinase | 0.018 | ||
| Akt3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.018 | ||
| Kif20b | kinesin family member 20B | 0.018 | ||
| Mcm5 | minichromosome maintenance complex component 5 | 0.017 | ||
| Bcr | breakpoint cluster region | 0.017 | ||
| Espl1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.017 | ||
| Brca2 | breast cancer 2 | 0.017 | ||
| Rpl22 | ribosomal protein L22 | 0.017 | ||
| Myo1b | myosin Ib | 0.017 | ||
| Bbx | bobby sox homolog (Drosophila) | 0.016 | ||
| Rnd3 | Rho family GTPase 3 | 0.016 | ||
| Myo1c | myosin IC | 0.016 | ||
| Cenpf | centromere protein F | 0.016 | ||
| Traf4af1 | TRAF4 associated factor 1 | 0.016 | ||
| Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.016 | ||
| Itgb1 | integrin, beta 1 | 0.015 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.015 | ||
| Klk1c10 | T-kininogenase | 0.015 | ||
| Pkn2 | protein kinase N2 | 0.015 | ||
| Troap | trophinin associated protein | 0.014 | ||
| Tubgcp2 | tubulin, gamma complex associated protein 2 | 0.014 | ||
| Foxd4 | forkhead box D4 | 0.014 | ||
| Nuf2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.014 | ||
| Akap11 | A kinase (PRKA) anchor protein 11 | 0.014 | ||
| Efhd2 | EF-hand domain family, member D2 | 0.014 | ||
| Kif18b | kinesin family member 18B | 0.014 | ||
| Depdc1b | DEP domain containing 1B | 0.014 | ||
| Ppp1r9a | protein phosphatase 1, regulatory (inhibitor) subunit 9A | 0.014 | ||
| Kif4 | kinesin family member 4 | 0.014 | ||
| Nes | nestin | 0.013 | ||
| Aurka | aurora kinase A | 0.013 | ||
| Uhrf1 | ubiquitin-like with PHD and ring finger domains 1 | 0.013 | ||
| Cul1 | cullin 1 | 0.013 | ||
| Cep78 | centrosomal protein 78 | 0.013 | ||
| Tle4 | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 0.013 | ||
| Wdr26 | WD repeat domain 26 | 0.013 | ||
| Aurkb | aurora kinase B | 0.013 | ||
| Cenpt | centromere protein T | 0.013 | ||
| Epn1 | Epsin 1 | 0.013 | ||
| Kcnn1 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 | 0.013 | ||
| Taok1 | TAO kinase 1 | 0.013 | ||
| Stk17b | serine/threonine kinase 17b | 0.013 | ||
| Haus4 | HAUS augmin-like complex, subunit 4 | 0.013 | ||
| Pank2 | pantothenate kinase 2 (Hallervorden-Spatz syndrome) | 0.013 | ||
| Taok2 | TAO kinase 2 | 0.013 | ||
| Ccnb2 | cyclin B2 | 0.013 | ||
| Ska1 | spindle and kinetochore associated complex subunit 1 | 0.013 | ||
| Mcm7 | minichromosome maintenance complex component 7 | 0.013 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.013 | ||
| Arih1 | ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) | 0.013 | ||
| Gna11 | guanine nucleotide binding protein, alpha 11 | 0.013 | ||
| Usp9x | ubiquitin specific peptidase 9, X-linked | 0.013 | ||
| Cnot2 | CCR4-NOT transcription complex, subunit 2 | 0.013 | ||
| Eef1g | eukaryotic translation elongation factor 1 gamma | 0.013 | ||
| Eps15 | epidermal growth factor receptor pathway substrate 15 | 0.012 | ||
| Pbk | PDZ binding kinase | 0.012 | ||
| Slit1 | slit homolog 1 (Drosophila) | 0.012 | ||
| Timm44 | translocase of inner mitochondrial membrane 44 homolog (yeast) | 0.012 | ||
| Myh10 | myosin, heavy chain 10, non-muscle | 0.012 | ||
| Kif22 | kinesin family member 22 | 0.012 | ||
| Cdca2 | cell division cycle associated 2 | 0.012 | ||
| Mras | muscle RAS oncogene homolog | 0.012 | ||
| Clic1 | chloride intracellular channel 1 | 0.012 | ||
| Pacs1 | phosphofurin acidic cluster sorting protein 1 | 0.012 | ||
| Fabp9 | fatty acid binding protein 9, testis | 0.012 | ||
| Mdm2 | Mdm2 p53 binding protein homolog (mouse) | 0.012 | ||
| Camkk2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | 0.012 | ||
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.012 | ||
| Ckap2 | cytoskeleton associated protein 2 | 0.012 | ||
| Cenpi | centromere protein I | 0.012 | ||
| Mak | male germ cell-associated kinase | 0.012 | ||
| Cd24 | CD24 molecule | 0.012 | ||
| Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.012 | ||
| Kcnn3 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 0.012 | ||
| Ccne1 | cyclin E1 | 0.012 | Fly | |
| Racgap1 | Rac GTPase-activating protein 1 | 0.012 | ||
| Prkaca | protein kinase, cAMP-dependent, catalytic, alpha | 0.012 | ||
| Hist1h1d | histone cluster 1, H1d | 0.011 | ||
| Cenpn | centromere protein N | 0.011 | ||
| Ndrg2 | N-myc downstream regulated gene 2 | 0.011 | ||
| Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.011 | ||
| Gins4 | GINS complex subunit 4 (Sld5 homolog) | 0.011 | ||
| Cd82 | Cd82 molecule | 0.011 | ||
| Ccnf | cyclin F | 0.011 | ||
| Ralb | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 0.011 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.011 | ||
| Lenep | lens epithelial protein | 0.011 | ||
| Ptp4a2 | protein tyrosine phosphatase 4a2 | 0.011 | ||
| Bard1 | BRCA1 associated RING domain 1 | 0.011 | ||
| Nid67 | putative small membrane protein NID67 | 0.011 | ||
| Vapa | VAMP (vesicle-associated membrane protein)-associated protein A | 0.011 | ||
| Mre11a | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.011 | ||
| Ptpru | protein tyrosine phosphatase, receptor type, U | 0.011 | ||
| March7 | membrane-associated ring finger (C3HC4) 7 | 0.011 | ||
| Cenpq | centromere protein Q | 0.011 | ||
| Slc28a1 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 | 0.011 | ||
| Gmfb | glia maturation factor, beta | 0.011 | ||
| Rad54l | RAD54 like (S. cerevisiae) | 0.011 | ||
| Acr | acrosin | 0.011 | ||
| Rad51c | Rad51 homolog c (S. cerevisiae) | 0.011 | ||
| Adrm1 | adhesion regulating molecule 1 | 0.011 | ||
| Plcl1 | phospholipase C-like 1 | 0.011 | ||
| Sema6b | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.011 | ||
| Man1a1 | mannosidase, alpha, class 1A, member 1 | 0.011 | ||
| Ccng1 | cyclin G1 | 0.011 | ||
| Alcam | activated leukocyte cell adhesion molecule | 0.011 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.011 | ||
| Mtdh | metadherin | 0.011 | ||
| Snrpa | small nuclear ribonucleoprotein polypeptide A | 0.011 | ||
| Dusp5 | dual specificity phosphatase 5 | 0.011 | ||
| Actr2 | ARP2 actin-related protein 2 homolog (yeast) | 0.011 | ||
| Eftud2 | elongation factor Tu GTP binding domain containing 2 | 0.011 | ||
| Dpp9 | dipeptidyl peptidase 9 | 0.011 | ||
| Zfp189 | zinc finger protein 189 | 0.011 | ||
| Pcgf5 | polycomb group ring finger 5 | 0.011 | ||
| Kpna3 | karyopherin alpha 3 | 0.011 | ||
| Traip | TRAF-interacting protein | 0.011 | ||
| Rab27a | RAB27A, member RAS oncogene family | 0.011 | ||
| Cacna1s | calcium channel, voltage-dependent, L type, alpha 1S subunit | 0.011 | ||
| Pkmyt1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.010 | ||
| Sirt7 | sirtuin 7 (silent mating type information regulation 2, homolog) 7 (S. cerevisiae) | 0.010 | ||
| Kif2a | kinesin family member 2A | 0.010 | ||
| Ddx50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.010 | ||
| Atp6v0a1 | ATPase, H+ transporting, lysosomal V0 subunit A1 | 0.010 | ||
| Pou2f2 | POU class 2 homeobox 2 | 0.010 | ||
| Cdk2 | cyclin dependent kinase 2 | 0.010 | ||
| Gata3 | GATA binding protein 3 | 0.010 | ||
| Wdfy1 | WD repeat and FYVE domain containing 1 | 0.010 | ||
| Acsl5 | acyl-CoA synthetase long-chain family member 5 | 0.010 | ||
| Grk5 | G protein-coupled receptor kinase 5 | 0.010 | ||
| Lamc1 | laminin, gamma 1 | 0.010 | ||
| Cdca8 | cell division cycle associated 8 | 0.010 | ||
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.010 | ||
| Aqp3 | aquaporin 3 | 0.010 | ||
| Gtlf3b | gene trap locus F3b | 0.010 | ||
| Rgs19 | regulator of G-protein signaling 19 | 0.010 | ||
| Arl6ip6 | ADP-ribosylation-like factor 6 interacting protein 6 | 0.010 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.010 | ||
| Mapre3 | microtubule-associated protein, RP/EB family, member 3 | 0.010 | ||
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.010 | ||
| Plat | plasminogen activator, tissue | 0.010 | ||
| Map3k7 | mitogen activated protein kinase kinase kinase 7 | 0.010 |