IMP: Integrative Multi-species Prediction

Rattus norvegicus

23 genes annotated in rat

Multi-species View

hormone mediated signaling pathway

GO:0009755

A series of molecular signals mediated by the detection of a hormone.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in ratInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hormone mediated signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "hormone mediated signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.377
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.219
Avp	arginine vasopressin	0.211
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.187
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.172
Cckbr	cholecystokinin B receptor	0.136
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.120
Mag	myelin-associated glycoprotein	0.110
Gck	glucokinase	0.105
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.101
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.094
Hrh3	histamine receptor H3	0.090
Crhbp	corticotropin releasing hormone binding protein	0.088
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.084
Mamdc4	MAM domain containing 4	0.084
Ncan	neurocan	0.084
Slc18a3	solute carrier family 18 (vesicular acetylcholine), member 3	0.083
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.082
Kl	Klotho	0.076
Glra1	glycine receptor, alpha 1	0.071
Cyss	cystatin S	0.070
Ghr	growth hormone receptor	0.068
Shank2	SH3 and multiple ankyrin repeat domains 2	0.066
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.065
Shox2	short stature homeobox 2	0.065
Ptger3	prostaglandin E receptor 3 (subtype EP3)	0.063
Prlr	prolactin receptor	0.063
Vip	vasoactive intestinal peptide	0.062
Tbxa2r	thromboxane A2 receptor	0.061
Th	tyrosine hydroxylase	0.057
Csn2	casein beta	0.057
RGD1310262	hypothetical LOC304650	0.056
Aqp2	aquaporin 2 (collecting duct)	0.055
Lep	leptin	0.055
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.053
Gpr1	G protein-coupled receptor 1	0.051
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.047
Uncx	UNC homeobox	0.047
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.046
Fgf14	fibroblast growth factor 14	0.046
Ptch1	patched homolog 1 (Drosophila)	0.045
Cpb1	carboxypeptidase B1 (tissue)	0.045
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.044
Adra2b	adrenergic, alpha-2B-, receptor	0.044
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.044
Cfp	complement factor properdin	0.042
Nrg1	neuregulin 1	0.042
Umod	uromodulin	0.040
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.040
Gpr6	G protein-coupled receptor 6	0.039
Nlrp6	NLR family, pyrin domain containing 6	0.039
Pcdhb12	protocadherin beta 12	0.038
Slc5a2	solute carrier family 5 (sodium/glucose cotransporter), member 2	0.038
Olr1867	olfactory receptor 1867	0.038
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.037
Pdyn	prodynorphin	0.036
Agxt2	alanine-glyoxylate aminotransferase 2	0.036
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.035
Agtr1a	angiotensin II receptor, type 1a	0.035
Hcrt	hypocretin	0.035
Pklr	pyruvate kinase, liver and RBC	0.035
Cckar	cholecystokinin A receptor	0.034
Bcan	brevican	0.033
Lhb	luteinizing hormone beta	0.033
Agtr2	angiotensin II receptor, type 2	0.032
Gja6	gap junction protein, alpha 6	0.032
Kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.032
Kynu	kynureninase (L-kynurenine hydrolase)	0.032
Hoxc4	homeo box C4	0.031
Grp	gastrin releasing peptide	0.031
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.030
Ghrl	ghrelin/obestatin prepropeptide	0.030
Csrnp2	cysteine-serine-rich nuclear protein 2	0.030
Il8ra	interleukin 8 receptor, alpha	0.030
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1	0.029
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.029
Smgb	neonatal submandibular gland protein B	0.029
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.028
Pnoc	prepronociceptin	0.028
Tnni3	troponin I type 3 (cardiac)	0.028
Nmnat2	nicotinamide nucleotide adenylyltransferase 2	0.028
Mapk9	mitogen-activated protein kinase 9	0.027
Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.027
Il9r	interleukin 9 receptor	0.027
Gip	gastric inhibitory polypeptide	0.027
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.027
Grm8	glutamate receptor, metabotropic 8	0.027
Plin	perilipin	0.026
Chrm5	cholinergic receptor, muscarinic 5	0.026
Slc8a3	solute carrier family 8 (sodium/calcium exchanger), member 3	0.026
Irs3	insulin receptor substrate 3	0.026
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.026
Rgs9	regulator of G-protein signaling 9	0.025
Esr2	estrogen receptor 2 (ER beta)	0.025
Pdzk1	PDZ domain containing 1	0.024
P2ry1	purinergic receptor P2Y, G-protein coupled, 1	0.024
Etfdh	electron-transferring-flavoprotein dehydrogenase	0.024
Chrna3	cholinergic receptor, nicotinic, alpha 3	0.024
Rgs12	regulator of G-protein signaling 12	0.024
Pkia	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	0.024
Dcc	deleted in colorectal carcinoma	0.023
Faslg	Fas ligand (TNF superfamily, member 6)	0.023
Accn2	amiloride-sensitive cation channel 2, neuronal	0.023
Tmod2	tropomodulin 2	0.023
Sst	somatostatin	0.023
Pde1c	phosphodiesterase 1C	0.023
Rxrg	retinoid X receptor gamma	0.023
Prss3	protease, serine, 3	0.023
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.023
Smcp	sperm mitochondria-associated cysteine-rich protein	0.023
Grin3a	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	0.023
Hhip	Hedgehog-interacting protein	0.023
Aqp9	aquaporin 9	0.023
Uhmk1	U2AF homology motif (UHM) kinase 1	0.022
Itgb1	integrin, beta 1	0.022
Grin2c	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.022
Eed	embryonic ectoderm development	0.022
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.022
Tubb3	tubulin, beta 3	0.022
Rup2	urinary protein 2	0.022
Hbg1	hemoglobin, gamma A	0.022
Drd3	dopamine receptor D3	0.022
Calcr	calcitonin receptor	0.022	Rat Fly
Prlhr	prolactin releasing hormone receptor	0.022
Isl1	ISL LIM homeobox 1	0.022
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.022
Adra2c	adrenergic, alpha-2C-, receptor	0.021
Npy5r	neuropeptide Y receptor Y5	0.021
Crygf	crystallin, gamma F	0.021
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.021
Calca	calcitonin-related polypeptide alpha	0.021
Rhox5	reproductive homeobox 5	0.021
Cd36	CD36 molecule (thrombospondin receptor)	0.021
Lbxcor1	LBXCOR1 homolog (mouse)	0.020
Dlg1	discs, large homolog 1 (Drosophila)	0.020
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.020
Adora1	adenosine A1 receptor	0.020
Mlxipl	MLX interacting protein-like	0.020
Clstn3	calsyntenin 3	0.020
Olr1654	olfactory receptor 1654	0.020
Cgm4	carcinoembryonic antigen gene family 4	0.020
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.020
Grm6	glutamate receptor, metabotropic 6	0.019
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.019
Gfra4	GDNF family receptor alpha 4	0.019
Fat2	FAT tumor suppressor homolog 2 (Drosophila)	0.019
Hnf1b	HNF1 homeobox B	0.019
Ppp1r3b	protein phosphatase 1, regulatory (inhibitor) subunit 3B	0.019
Igf2	insulin-like growth factor 2	0.019
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.019
Testin	testin gene	0.019
Nfia	nuclear factor I/A	0.019
A4galt	alpha 1,4-galactosyltransferase	0.019
Csn1s1	casein alpha s1	0.019
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.019
LOC64038	sertolin	0.019
Hand1	heart and neural crest derivatives expressed 1	0.018
Ncr1	natural cytotoxicity triggering receptor 1	0.018
Cort	cortistatin	0.018
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.018
Slc16a8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.018
Oxtr	oxytocin receptor	0.018
Necab2	N-terminal EF-hand calcium binding protein 2	0.018
Galr2	galanin receptor 2	0.018	Rat
Hbp1	HMG-box transcription factor 1	0.018
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.018
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.018
Serp2	stress-associated endoplasmic reticulum protein family member 2	0.018
Kcnh6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.018
Aqp8	aquaporin 8	0.017
Lhx5	LIM homeobox 5	0.017
Cela2a	chymotrypsin-like elastase family, member 2A	0.017
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.017
Egfr	epidermal growth factor receptor	0.017
Nmbr	neuromedin B receptor	0.017
Onecut1	one cut homeobox 1	0.017
RGD1306926	similar to hypothetical protein FLJ22175	0.016
Slc30a1	solute carrier family 30 (zinc transporter), member 1	0.016
Fgf11	fibroblast growth factor 11	0.016
Clps	colipase, pancreatic	0.016
Olr37	olfactory receptor 37	0.016
LOC100360403	ATP-binding cassette, sub-family C, member 9-like	0.016
Chrnb3	cholinergic receptor, nicotinic, beta 3	0.016
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.016
Pdk2	pyruvate dehydrogenase kinase, isozyme 2	0.016
Syt8	synaptotagmin VIII	0.016
Mep1a	meprin 1 alpha	0.015
Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	0.015
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.015
Bcl2	B-cell CLL/lymphoma 2	0.015
Snap91	synaptosomal-associated protein 91	0.015
Barhl1	BarH-like homeobox 1	0.015
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.015
Ralgds	ral guanine nucleotide dissociation stimulator	0.014
Enpep	glutamyl aminopeptidase	0.014
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.014
Ghsr	growth hormone secretagogue receptor	0.014	Human
Chat	choline acetyltransferase	0.014
Stat5b	signal transducer and activator of transcription 5B	0.014	Mouse
Map2k4	mitogen activated protein kinase kinase 4	0.014
Ptprq	protein tyrosine phosphatase, receptor type, Q	0.014
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.014
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.014
Prkg2	protein kinase, cGMP-dependent, type II	0.014
F9	coagulation factor IX	0.014
Ccnl1	cyclin L1	0.014
Mtus1	mitochondrial tumor suppressor 1	0.014
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.014
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.014
Asb9	ankyrin repeat and SOCS box-containing 9	0.014
Rev1	REV1 homolog (S. cerevisiae)	0.014
Lpar2	lysophosphatidic acid receptor 2	0.014
Tas2r118	taste receptor, type 2, member 118	0.014
Cst8	cystatin 8 (cystatin-related epididymal specific)	0.014
Gnaz	guanine nucleotide binding protein (G protein), alpha z polypeptide	0.014
Ugt2b7	UDP glucuronosyltransferase 2 family, polypeptide B7	0.014
Prdm2	PR domain containing 2, with ZNF domain	0.013
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.013
Manea	mannosidase, endo-alpha	0.013
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.013
Tmem79	transmembrane protein 79	0.013
Calcrl	calcitonin receptor-like	0.013	Rat Fly
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
Csnk1a1	casein kinase 1, alpha 1	0.013
Grik3	glutamate receptor, ionotropic, kainate 3	0.013
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.013
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.013
Neurl2	neuralized homolog 2 (Drosophila)	0.013
Akirin2	akirin 2	0.013
Kit	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.013
Krt86	keratin 86	0.013
Man2c1	mannosidase, alpha, class 2C, member 1	0.013
Nkx6-1	NK6 homeobox 1	0.013
A1bg	alpha-1-B glycoprotein	0.013
Ctrb1	chymotrypsinogen B1	0.012
Prp2	proline rich protein 2	0.012
Acadsb	acyl-Coenzyme A dehydrogenase, short/branched chain	0.012
Notch3	Notch homolog 3 (Drosophila)	0.012
Begain	brain-enriched guanylate kinase-associated	0.012
Oprk1	opioid receptor, kappa 1	0.012	Rat
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.012
Znf746	zinc finger protein 746	0.012
Il6st	interleukin 6 signal transducer	0.012
Pip	prolactin induced protein	0.012
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.012
Scp2	sterol carrier protein 2	0.012
Jak1	Janus kinase 1	0.012
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive	0.012
Neu2	sialidase 2 (cytosolic sialidase)	0.012
Gfra2	GDNF family receptor alpha 2	0.012
Man2b1	mannosidase, alpha, class 2B, member 1	0.012
Xpc	xeroderma pigmentosum, complementation group C	0.012
Egr4	early growth response 4	0.012
Msx2	msh homeobox 2	0.012
Foxd1	forkhead box D1	0.012
Vipr1	vasoactive intestinal peptide receptor 1	0.012
Omp	olfactory marker protein	0.012
Il1rl1	interleukin 1 receptor-like 1	0.012
Catsper2	cation channel, sperm associated 2	0.012
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.012
Pnmt	phenylethanolamine-N-methyltransferase	0.012
Lrp3	low density lipoprotein receptor-related protein 3	0.012
Insrr	insulin receptor-related receptor	0.012
Tor1aip1	torsin A interacting protein 1	0.011
Slc12a3	solute carrier family 12 (sodium/chloride transporters), member 3	0.011
Olr1696	olfactory receptor 1696	0.011
Fshb	follicle stimulating hormone, beta polypeptide	0.011
Klhdc8a	kelch domain containing 8A	0.011
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.011
Smr3a	submaxillary gland androgen regulated protein 3A	0.011
Hdac1l	histone deacetylase 1-like	0.011
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.011
Iapp	islet amyloid polypeptide	0.011
Epor	erythropoietin receptor	0.011
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.011
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.011
Vom2r32	vomeronasal 2 receptor, 32	0.011
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.011
Rasgef1c	RasGEF domain family, member 1C	0.011
Prrt4	proline-rich transmembrane protein 4	0.011
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.011
Chpt1	choline phosphotransferase 1	0.011
Fgf10	fibroblast growth factor 10	0.011
Ghrhr	growth hormone releasing hormone receptor	0.011	Rat
Zfp191	zinc finger protein 191	0.011
Slc7a12	solute carrier family 7 (cationic amino acid transporter, y+ system), member 12	0.011
Gjb4	gap junction protein, beta 4	0.011
Sstr4	somatostatin receptor 4	0.011
Npffr2	neuropeptide FF receptor 2	0.011
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
Dao	D-amino-acid oxidase	0.011
Troap	trophinin associated protein	0.011
Padi3	peptidyl arginine deiminase, type III	0.011
Obp2b	odorant binding protein 2B	0.011
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.010
Prg2	proteoglycan 2, bone marrow	0.010
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.010
Pon1	paraoxonase 1	0.010
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.010
Gucy1a2	guanylate cyclase 1, soluble, alpha 2	0.010
Atp4a	ATPase, H+/K+ exchanging, alpha polypeptide	0.010
Vom1r101	vomeronasal 1 receptor 101	0.010
Man1a1	mannosidase, alpha, class 1A, member 1	0.010
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.010
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.010
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.010
Smad3	SMAD family member 3	0.010
Mertk	c-mer proto-oncogene tyrosine kinase	0.010
Flt1	FMS-related tyrosine kinase 1	0.010
RGD1304644	similar to RIKEN cDNA 2310046K01	0.010
Dusp7	dual specificity phosphatase 7	0.010