IMP: Integrative Multi-species Prediction

Rattus norvegicus

260 genes annotated in rat

negative regulation of macromolecule metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of macromolecule metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of macromolecule metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Junb	jun B proto-oncogene	0.669
Dusp1	dual specificity phosphatase 1	0.643
Errfi1	ERBB receptor feedback inhibitor 1	0.587
Dbp	D site of albumin promoter (albumin D-box) binding protein	0.580
Ifitm3	interferon induced transmembrane protein 3	0.553	Human
Nfya	nuclear transcription factor-Y alpha	0.550
Eif4h	eukaryotic translation initiation factor 4H	0.547
Btg2	BTG family, member 2	0.532
Met	met proto-oncogene	0.495
Jun	Jun oncogene	0.459	Human Mouse
Klf9	Kruppel-like factor 9	0.405
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.399
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.399	Mouse
Fos	FBJ osteosarcoma oncogene	0.397	Rat
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.384	Human Mouse
Casp2	caspase 2	0.368
Foxi2	forkhead box I2	0.346
Ppp2cb	protein phosphatase 2, catalytic subunit, beta isoform	0.336	Rat
Anxa5	annexin A5	0.329
Sfrs1	splicing factor, arginine/serine-rich 1	0.321
Dynll1	dynein light chain LC8-type 1	0.320
S100a10	S100 calcium binding protein A10	0.300	Rat
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.297	Rat
Tgfbr2	transforming growth factor, beta receptor II	0.284
Adra2b	adrenergic, alpha-2B-, receptor	0.277
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.277
Nrg2	neuregulin 2	0.274
Irs1	insulin receptor substrate 1	0.274
Stip1	stress-induced phosphoprotein 1	0.269
Tcfe2a	transcription factor E2a	0.269	Human
Cd9	CD9 molecule	0.266
Rhob	ras homolog gene family, member B	0.266
Iapp	islet amyloid polypeptide	0.262
Rest	RE1-silencing transcription factor	0.254
Klf4	Kruppel-like factor 4 (gut)	0.248
Arpc1b	actin related protein 2/3 complex, subunit 1B	0.248
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.245
Asgr1	asialoglycoprotein receptor 1	0.243
Ier2	immediate early response 2	0.243
Mgp	matrix Gla protein	0.239
Cdk2	cyclin dependent kinase 2	0.237	Human Yeast
Stat6	signal transducer and activator of transcription 6	0.236	Mouse Rat
Jak1	Janus kinase 1	0.235
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.235	Yeast Mouse
Nfia	nuclear factor I/A	0.233	Rat
Thbd	thrombomodulin	0.231
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.230
Anxa4	annexin A4	0.228
Kdm6b	lysine (K)-specific demethylase 6B	0.228
Sgk1	serum/glucocorticoid regulated kinase 1	0.227
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.227
Arf6	ADP-ribosylation factor 6	0.219
Adora2a	adenosine A2a receptor	0.218
Slc30a1	solute carrier family 30 (zinc transporter), member 1	0.216
Hes1	hairy and enhancer of split 1 (Drosophila)	0.215
Lbr	lamin B receptor	0.213
Galr3	galanin receptor 3	0.210
Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2	0.210
Smad2	SMAD family member 2	0.207	Human Rat
Rara	retinoic acid receptor, alpha	0.207
Egr1	early growth response 1	0.206	Mouse
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.206
Creb1	cAMP responsive element binding protein 1	0.205	Human
Onecut1	one cut homeobox 1	0.202
Jak2	Janus kinase 2	0.201
Gja1	gap junction protein, alpha 1	0.199
Trim47	tripartite motif-containing 47	0.197
Dchs1	dachsous 1 (Drosophila)	0.196
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.191	Rat
Ambp	alpha-1-microglobulin/bikunin precursor	0.191
Tcp11	t-complex protein 11	0.190
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.190	Rat
Cdk4	cyclin-dependent kinase 4	0.187
Smad7	SMAD family member 7	0.186
Myo1b	myosin Ib	0.185
Lif	leukemia inhibitory factor	0.184
Smad6	SMAD family member 6	0.184	Rat
Hoxb7	homeo box B7	0.184
Dcc	deleted in colorectal carcinoma	0.182
Top2a	topoisomerase (DNA) II alpha	0.182
Ptprk	protein tyrosine phosphatase, receptor type, K, extracellular region	0.181
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.181
Metap2	methionyl aminopeptidase 2	0.179
Flt1	FMS-related tyrosine kinase 1	0.179
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.179	Mouse
Scn4a	sodium channel, voltage-gated, type IV, alpha subunit	0.178
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.177
Mbl1	mannose-binding lectin (protein A) 1	0.177
Il12b	interleukin 12B	0.177
Slc15a1	solute carrier family 15 (oligopeptide transporter), member 1	0.177
Nrgn	neurogranin	0.176
Tcf4	transcription factor 4	0.176	Mouse
Bat1	HLA-B associated transcript 1	0.175	Yeast
Slc18a3	solute carrier family 18 (vesicular acetylcholine), member 3	0.174
Alx1	ALX homeobox 1	0.174	Human
Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.173
Phlda1	pleckstrin homology-like domain, family A, member 1	0.173
F2	coagulation factor II (thrombin)	0.172	Human
Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.172
Abcb4	ATP-binding cassette, subfamily B (MDR/TAP), member 4	0.172
Phkg1	phosphorylase kinase, gamma 1	0.171
Robo1	roundabout homolog 1 (Drosophila)	0.170
Sox17	SRY (sex determining region Y)-box 17	0.169	Rat Fly
Foxa3	forkhead box A3	0.169	Rat
Susd3	sushi domain containing 3	0.168
Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.166
Wt1	Wilms tumor 1	0.165	Human Mouse
Spp2	secreted phosphoprotein 2	0.164
Ncr3	natural cytotoxicity triggering receptor 3	0.164
Cxxc4	CXXC finger 4	0.163
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.161
S100a9	S100 calcium binding protein A9	0.160	Rat
Gjb3	gap junction protein, beta 3	0.160
Id3	inhibitor of DNA binding 3	0.160	Human Mouse Fly
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.160
Nfib	nuclear factor I/B	0.160	Rat
S100a8	S100 calcium binding protein A8	0.159	Rat
Taok1	TAO kinase 1	0.159
Adrm1	adhesion regulating molecule 1	0.159
Hist1h2aa	histone cluster 1, H2aa	0.159
Vom2r27	vomeronasal 2 receptor, 27	0.159
Gzmk	granzyme K	0.157
Adam10	ADAM metallopeptidase domain 10	0.157
Usf2	upstream transcription factor 2, c-fos interacting	0.156
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.156
Vax2	ventral anterior homeobox 2	0.156	Mouse
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.155
Tubb5	tubulin, beta 5	0.155
Fgfr2	fibroblast growth factor receptor 2	0.154	Mouse
Nrg1	neuregulin 1	0.154	Human Mouse
Ptafr	platelet-activating factor receptor	0.154
Nfix	nuclear factor I/X (CCAAT-binding transcription factor)	0.153	Human Rat
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.153
Fosl1	fos-like antigen 1	0.153	Rat
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.153
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.153	Mouse
Icam1	intercellular adhesion molecule 1	0.152
Dlg1	discs, large homolog 1 (Drosophila)	0.152	Rat Fly
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.152
Plagl1	pleiomorphic adenoma gene-like 1	0.152
Baiap2	BAI1-associated protein 2	0.151
Lgals3	lectin, galactoside-binding, soluble, 3	0.151
Pde4b	phosphodiesterase 4B, cAMP specific	0.151
Ccnd3	cyclin D3	0.151
Homer3	homer homolog 3 (Drosophila)	0.151
Gnrhr	gonadotropin releasing hormone receptor	0.150
Wbp11	WW domain binding protein 11	0.150
Acadsb	acyl-Coenzyme A dehydrogenase, short/branched chain	0.149
Fgg	fibrinogen gamma chain	0.149
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.148
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.148
Tmem27	transmembrane protein 27	0.148
Mllt4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.147
Zfp36	zinc finger protein 36	0.147	Human Fly
Pzp	pregnancy-zone protein	0.147	Rat
Tsc22d3	TSC22 domain family, member 3	0.146	Mouse
Trim28	tripartite motif-containing 28	0.146	Human Mouse
Tspo	translocator protein	0.146
Hist1h1d	histone cluster 1, H1d	0.145
Adcy4	adenylate cyclase 4	0.145
Rnf138	ring finger protein 138	0.145
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.145
Arih1	ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)	0.145
Ccdc117	coiled-coil domain containing 117	0.144
Lhb	luteinizing hormone beta	0.144
Isl1	ISL LIM homeobox 1	0.144	Mouse
S1pr2	sphingosine-1-phosphate receptor 2	0.144
Myo1c	myosin IC	0.144
Pgam1	phosphoglycerate mutase 1 (brain)	0.144
Phox2a	paired-like homeobox 2a	0.143
Axin1	axin 1	0.143	Mouse
Apoa2	apolipoprotein A-II	0.143
Lsm14a	LSM14A, SCD6 homolog A (S. cerevisiae)	0.142
Hand2	heart and neural crest derivatives expressed 2	0.142
Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit	0.141
Il7	interleukin 7	0.140
Foxj1	forkhead box J1	0.140
Ptms	parathymosin	0.140	Rat
Pcna	proliferating cell nuclear antigen	0.140
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.140
Ppp1r2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.140	Fly
Lepr	leptin receptor	0.139
Vim	vimentin	0.139
Utrn	utrophin	0.139
C4bpa	complement component 4 binding protein, alpha	0.138	Human Rat
Ccl4	chemokine (C-C motif) ligand 4	0.138	Human
Id1	inhibitor of DNA binding 1	0.137	Human Mouse Fly
Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	0.137
Sox4	SRY (sex determining region Y)-box 4	0.136
Ewsr1	Ewing sarcoma breakpoint region 1	0.136
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.136
Klf6	Kruppel-like factor 6	0.136
Aqp2	aquaporin 2 (collecting duct)	0.136
Crx	cone-rod homeobox	0.135
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.135
Tef	thyrotrophic embryonic factor	0.135
Gabrr2	gamma-aminobutyric acid (GABA) receptor, rho 2	0.135
Egr2	early growth response 2	0.135
Bat3	HLA-B-associated transcript 3	0.134
Bmpr1a	bone morphogenetic protein receptor, type IA	0.134	Fly
Sox18	SRY (sex determining region Y)-box 18	0.134	Human Rat Fly
Shh	sonic hedgehog	0.134
Prrxl1	paired related homeobox protein-like 1	0.134	Rat
Prdm2	PR domain containing 2, with ZNF domain	0.134
Plb1	phospholipase B1	0.133
Fyn	FYN oncogene related to SRC, FGR, YES	0.133	Mouse Rat
Hp	haptoglobin	0.133
Nrp1	neuropilin 1	0.131
Klf13	Kruppel-like factor 13	0.131
Pdzd2	PDZ domain containing 2	0.130
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.129
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.128
Ddit3	DNA-damage inducible transcript 3	0.128
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.128	Yeast
Hpx	hemopexin	0.127
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.127
Ssrp1	structure specific recognition protein 1	0.127
Nras	neuroblastoma ras oncogene	0.126
Irs3	insulin receptor substrate 3	0.126
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.126
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.126
Gpc1	glypican 1	0.126
Cfp	complement factor properdin	0.126
F3	coagulation factor III (thromboplastin, tissue factor)	0.125
Cntfr	ciliary neurotrophic factor receptor	0.125
Atl3	atlastin GTPase 3	0.124
Crip	cysteine-rich intestinal protein	0.124
Tle4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	0.124	Mouse Fly
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.123
Zfand6	zinc finger, AN1-type domain 6	0.123
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.123
Muc13	mucin 13, cell surface associated	0.123
Arglu1	arginine and glutamate rich 1	0.123
Akap2	A kinase (PRKA) anchor protein 2	0.122
Proc	protein C	0.122
Orm1	orosomucoid 1	0.122
Klf2	Kruppel-like factor 2 (lung)	0.122
Homer1	homer homolog 1 (Drosophila)	0.122
Tpbpa	trophoblast specific protein alpha	0.121
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.121
Syt6	synaptotagmin VI	0.121
Cd40lg	CD40 ligand	0.121
Nab1	Ngfi-A binding protein 1	0.121
Plcg2	phospholipase C, gamma 2	0.120
Cntn4	contactin 4	0.120
Syngap1	synaptic Ras GTPase activating protein 1 homolog (rat)	0.120
Hbg1	hemoglobin, gamma A	0.120	Mouse
Gata4	GATA binding protein 4	0.119
Grip2	glutamate receptor interacting protein 2	0.119
Lpl	lipoprotein lipase	0.119
Stat5b	signal transducer and activator of transcription 5B	0.119	Rat
Hmgb1	high mobility group box 1	0.119
St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.119
C1s	complement component 1, s subcomponent	0.119
Jund	jun D proto-oncogene	0.118
Rab13	RAB13, member RAS oncogene family	0.118
Tnp2	transition protein 2	0.118
Rgs19	regulator of G-protein signaling 19	0.118
Ccdc49	coiled-coil domain containing 49	0.118
Ing1	inhibitor of growth family, member 1	0.117
Il15	interleukin 15	0.117
Csda	cold shock domain protein A	0.117
LOC64038	sertolin	0.117
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.116
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.116
Hdac2	histone deacetylase 2	0.116
Synpo	synaptopodin	0.116
Tp53	tumor protein p53	0.116
Ccl20	chemokine (C-C motif) ligand 20	0.116
Timeless	timeless homolog (Drosophila)	0.116
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.115
Hspb1	heat shock protein 1	0.115
Cdc7	cell division cycle 7 homolog (S. cerevisiae)	0.115
Palm	paralemmin	0.115
Hnrpd	heterogeneous nuclear ribonucleoprotein D	0.115	Fly
Cyth2	cytohesin 2	0.115
LOC100360587	hypothetical protein LOC100360587	0.115
Igfbp5	insulin-like growth factor binding protein 5	0.115	Human
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.115	Mouse
Gys2	glycogen synthase 2	0.115
Lphn2	latrophilin 2	0.115
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.114	Mouse
Nrarp	Notch-regulated ankyrin repeat protein	0.114
Guca2a	guanylate cyclase activator 2a (guanylin)	0.114
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.114	Rat
Sfrs2	splicing factor, arginine/serine-rich 2	0.114
Spam1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	0.113
Hoxc4	homeo box C4	0.113	Fly
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.113
Pfn1	profilin 1	0.113
Cxcl2	chemokine (C-X-C motif) ligand 2	0.113
Per2	period homolog 2 (Drosophila)	0.113
Dab2	disabled homolog 2 (Drosophila)	0.113	Human
Blmh	bleomycin hydrolase	0.113
Hn1	hematological and neurological expressed 1	0.112
Prdm12	PR domain containing 12	0.112
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.112
Cd44	Cd44 molecule	0.112	Human
Ttn	titin	0.112
Sfrs9	splicing factor, arginine/serine-rich 9	0.112	Human Yeast
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.112
Prkce	protein kinase C, epsilon	0.111
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.111	Mouse
Pou3f2	POU class 3 homeobox 2	0.111	Rat
Arhgap28	Rho GTPase activating protein 28	0.111
Actb	actin, beta	0.111
Uox	urate oxidase	0.111
Unc5b	unc-5 homolog B (C. elegans)	0.111
Cacna1i	calcium channel, voltage-dependent, T type, alpha 1I subunit	0.110
Rxrb	retinoid X receptor beta	0.110	Zebrafish Rat Worm
Grpr	gastrin releasing peptide receptor	0.110
Guca1b	guanylate cyclase activator 1B	0.110
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.110
Gse1	genetic suppressor element 1	0.110
Pim1	pim-1 oncogene	0.110	Yeast
Smcp	sperm mitochondria-associated cysteine-rich protein	0.110
Nos2	nitric oxide synthase 2, inducible	0.110	Human Mouse Rat
Igf1r	insulin-like growth factor 1 receptor	0.110	Human Zebrafish Rat
Zc3h11a	zinc finger CCCH-type containing 11A	0.109
Arf4	ADP-ribosylation factor 4	0.109
Calcrl	calcitonin receptor-like	0.109	Rat
Casp3	caspase 3	0.109
Csrnp1	cysteine-serine-rich nuclear protein 1	0.109
Prl8a9	prolactin family 8, subfamily a, member 9	0.109
Hoxa2	homeo box A2	0.109	Mouse
Gja5	gap junction protein, alpha 5	0.108	Rat
Crygb	crystallin, gamma B	0.108
Mybl2	myeloblastosis oncogene-like 2	0.108
Hbp1	HMG-box transcription factor 1	0.108
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.108
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.108
LOC100360491	60S ribosomal protein L13-like	0.108
Stat3	signal transducer and activator of transcription 3	0.108	Rat
Runx1	runt-related transcription factor 1	0.108
Gch1	GTP cyclohydrolase 1	0.108
Ppap2b	phosphatidic acid phosphatase type 2B	0.107	Human
Raf1	v-raf-leukemia viral oncogene 1	0.107
Ptbp1	polypyrimidine tract binding protein 1	0.107	Human Mouse Fly
Thra	thyroid hormone receptor alpha	0.107	Human Zebrafish Mouse Rat
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.107
Jdp2	Jun dimerization protein 2	0.107
Clcn5	chloride channel 5	0.107
Sorbs3	sorbin and SH3 domain containing 3	0.107
Hnrnpl	heterogeneous nuclear ribonucleoprotein L	0.107
Galr2	galanin receptor 2	0.107
Cd63	Cd63 molecule	0.106
Itgb1	integrin, beta 1	0.106
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.106
Myh13	myosin, heavy chain 13, skeletal muscle	0.106
Tbxa2r	thromboxane A2 receptor	0.106
Ccnb1	cyclin B1	0.106
Scaf1	SR-related CTD-associated factor 1	0.105
Tmpo	thymopoietin	0.105
Lat	linker for activation of T cells	0.105
Lig3	ligase III, DNA, ATP-dependent	0.105
Cckar	cholecystokinin A receptor	0.105
Svs4	seminal vesicle secretory protein 4	0.105
Myh9	myosin, heavy chain 9, non-muscle	0.105
Hdgf	hepatoma-derived growth factor	0.105
Ncan	neurocan	0.105
Anxa2	annexin A2	0.104
Kcnb2	potassium voltage gated channel, Shab-related subfamily, member 2	0.104
Crebbp	CREB binding protein	0.104	Human Rat
Ythdf1	YTH domain family, member 1	0.104
Slc12a1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.104
Fgf10	fibroblast growth factor 10	0.104
Nckap1	NCK-associated protein 1	0.103
Gck	glucokinase	0.103
Cmklr1	chemokine-like receptor 1	0.103
Cga	glycoprotein hormones, alpha polypeptide	0.103
Sh3bp1	SH3-domain binding protein 1	0.103
Fam108a1	family with sequence similarity 108, member A1	0.103
Faslg	Fas ligand (TNF superfamily, member 6)	0.103
Trpc2	transient receptor potential cation channel, subfamily C, member 2	0.103
Pdcd4	programmed cell death 4	0.102
Il18	interleukin 18	0.102
Gtf2i	general transcription factor II I	0.102
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.102	Rat
Mcm7	minichromosome maintenance complex component 7	0.102
Ttc36	tetratricopeptide repeat domain 36	0.102
Prkca	protein kinase C, alpha	0.102
Map3k3	mitogen activated protein kinase kinase kinase 3	0.101
Kcng2	potassium voltage-gated channel, subfamily G, member 2	0.101
Msh2	mutS homolog 2 (E. coli)	0.101
Pdcl	phosducin-like	0.100
Fga	fibrinogen alpha chain	0.100
Slfn2	schlafen 2	0.100
Hoxc8	homeo box C8	0.100
Siah1a	seven in absentia 1A	0.100
Cyp2a3	cytochrome P450, family 2, subfamily a, polypeptide 3	0.100
Pld4	phospholipase D family, member 4	0.100
Tecr	trans-2,3-enoyl-CoA reductase	0.100
Ptma	prothymosin alpha	0.100
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.099
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.099
Znf532	zinc finger protein 532	0.099
Gcm1	glial cells missing homolog 1 (Drosophila)	0.099
Mta2	metastasis associated 1 family, member 2	0.099
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.099	Rat
Cxxc5	CXXC finger 5	0.099
Notch1	Notch homolog 1, translocation-associated (Drosophila)	0.099	Mouse Fly
Atp5b	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.099
Fkbp5	FK506 binding protein 5	0.098
Gast	gastrin	0.098
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.098	Human Mouse Rat Worm Fly
Grk1	G protein-coupled receptor kinase 1	0.098
Bhlha15	basic helix-loop-helix family, member a15	0.098
Pawr	PRKC, apoptosis, WT1, regulator	0.098
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.098	Rat
Trib1	tribbles homolog 1 (Drosophila)	0.097	Human
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.097	Mouse
Gata6	GATA binding protein 6	0.097
Rb1	retinoblastoma 1	0.097	Human
Pdgfa	platelet-derived growth factor alpha polypeptide	0.097
Tcf12	transcription factor 12	0.097
Il1r1	interleukin 1 receptor, type I	0.096
Bcan	brevican	0.096
Amh	anti-Mullerian hormone	0.096
Ddx41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	0.096
Prkcb	protein kinase C, beta	0.096	Rat
Kifc1	kinesin family member C1	0.096
Kprp	keratinocyte proline-rich protein	0.096
Mmp2	matrix metallopeptidase 2	0.096
LOC100365106	rCG32755-like	0.095
Efemp2	EGF-containing fibulin-like extracellular matrix protein 2	0.095
Gstm7	glutathione S-transferase, mu 7	0.095
Map4k1	mitogen activated protein kinase kinase kinase kinase 1	0.095
Foxp1	forkhead box P1	0.095	Human Mouse
Gfap	glial fibrillary acidic protein	0.095
Atp1b3	ATPase, Na+/K+ transporting, beta 3 polypeptide	0.095
Gpha2	glycoprotein hormone alpha 2	0.095
Sh3gl1	SH3-domain GRB2-like 1	0.095
Kitlg	KIT ligand	0.095
Add3	adducin 3 (gamma)	0.094
Ccnd2	cyclin D2	0.094
Ryk	receptor-like tyrosine kinase	0.094
Ifitm2	interferon induced transmembrane protein 2	0.094	Human
Pgr	progesterone receptor	0.094
Inhbc	inhibin beta C	0.094
Kng2	kininogen 2	0.094
Calm2	calmodulin 2	0.094
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.094
Socs2	suppressor of cytokine signaling 2	0.094
Pim3	pim-3 oncogene	0.094
Anxa1	annexin A1	0.094
Pdpn	podoplanin	0.094
Ubtf	upstream binding transcription factor, RNA polymerase I	0.094	Mouse
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.094
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.094
Lzts2	leucine zipper, putative tumor suppressor 2	0.093
RGD1307621	hypothetical LOC314168	0.093
Mprip	myosin phosphatase Rho interacting protein	0.093
Hoxa1	homeo box A1	0.093
Hoxd3	homeo box D3	0.093
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.093
Pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	0.093
Matk	megakaryocyte-associated tyrosine kinase	0.093
Znf76	zinc finger protein 76 (expressed in testis)	0.093
Tmem86a	transmembrane protein 86A	0.093
Brd4	bromodomain containing 4	0.093
Ldb1	LIM domain binding 1	0.092	Human
Fam25a	family with sequence similarity 25, member A	0.092
Parp1	poly (ADP-ribose) polymerase 1	0.092
Ggt5	gamma-glutamyltransferase 5	0.092
Nrd1	nardilysin 1	0.092
Mov10	Moloney leukemia virus 10	0.092
Zfx	zinc finger protein X-linked	0.092
Rassf9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.092
Emx2	empty spiracles homeobox 2	0.092
Gabbr1	gamma-aminobutyric acid (GABA) B receptor 1	0.092
Socs3	suppressor of cytokine signaling 3	0.092
Ilkap	integrin-linked kinase-associated serine/threonine phosphatase 2C	0.092
Gria4	glutamate receptor, ionotrophic, AMPA 4	0.092
Rhd	Rh blood group, D antigen	0.092
Lrrc38	leucine rich repeat containing 38	0.091
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.091	Human Mouse
Rtn4	reticulon 4	0.091
LOC100360165	rCG29588-like	0.091
Sdc3	syndecan 3	0.091
Cfd	complement factor D (adipsin)	0.091
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.090	Human
Taar1	trace-amine-associated receptor 1	0.090
Pou3f1	POU class 3 homeobox 1	0.090
Acpp	acid phosphatase, prostate	0.090
Thrb	thyroid hormone receptor beta	0.090	Mouse Rat
Pcgf6	polycomb group ring finger 6	0.090	Human Mouse
Mcpt3	mast cell peptidase 3	0.090
G6pc	glucose-6-phosphatase, catalytic subunit	0.090
Klf10	Kruppel-like factor 10	0.090	Mouse Fly
MGC112830	similar to transcription factor	0.090
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.090
Trdmt1	tRNA aspartic acid methyltransferase 1	0.090
Gsn	gelsolin	0.090
Trip10	thyroid hormone receptor interactor 10	0.089
Ap2m1	adaptor-related protein complex 2, mu 1 subunit	0.089
Prss3	protease, serine, 3	0.089
Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.089
Fgf21	fibroblast growth factor 21	0.089
Rorb	RAR-related orphan receptor B	0.089
Snapap	SNAP-associated protein	0.089
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.089	Rat Fly
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.089
Pklr	pyruvate kinase, liver and RBC	0.089
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.089	Human
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.088
Gchfr	GTP cyclohydrolase I feedback regulator	0.088
Ppat	phosphoribosyl pyrophosphate amidotransferase	0.088
Mtus1	mitochondrial tumor suppressor 1	0.088
Eif4e2	eukaryotic translation initiation factor 4E family member 2	0.088	Fly
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.088	Rat
Nr1d2	nuclear receptor subfamily 1, group D, member 2	0.088
Grk5	G protein-coupled receptor kinase 5	0.088
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.088	Rat
Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.088
Cxcr3	chemokine (C-X-C motif) receptor 3	0.087
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.087
Tcf21	transcription factor 21	0.087	Human
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.087
Il6st	interleukin 6 signal transducer	0.087
Klk1c10l2	kallikrein 1-related peptidase c10-like 2	0.087
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.087
Gzmb	granzyme B	0.087
Oprm1	opioid receptor, mu 1	0.087
Mef2d	myocyte enhancer factor 2D	0.087
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.086
Ltb4r	leukotriene B4 receptor	0.086
Wiz	widely-interspaced zinc finger motifs	0.086
Msl1	male-specific lethal 1 homolog (Drosophila)	0.086
Hrg	histidine-rich glycoprotein	0.086
Ralgds	ral guanine nucleotide dissociation stimulator	0.086
Arx	aristaless related homeobox	0.086
Mthfr	methylenetetrahydrofolate reductase (NAD(P)H)	0.086
Emd	emerin	0.086
Calm1	calmodulin 1	0.086
Gpr4	G protein-coupled receptor 4	0.086
Syt10	synaptotagmin X	0.085
Cyss	cystatin S	0.085
Sik1	salt-inducible kinase 1	0.085
Cd37	CD37 molecule	0.085
Fgf18	fibroblast growth factor 18	0.085
Klre1	killer cell lectin-like receptor, family E, member 1	0.085
Gc	group specific component	0.085
Vasp	vasodilator-stimulated phosphoprotein	0.085
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.085	Mouse
Exoc3	exocyst complex component 3	0.085
Rho	rhodopsin	0.085
Xpo1	exportin 1, CRM1 homolog (yeast)	0.085
Pink1	PTEN induced putative kinase 1	0.085
Pde11a	phosphodiesterase 11A	0.085
Kpnb1	karyopherin (importin) beta 1	0.085
Hoxd9	homeo box D9	0.085
Znf746	zinc finger protein 746	0.085	Mouse
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.085
Gzmm	granzyme M (lymphocyte met-ase 1)	0.085
Klf15	Kruppel-like factor 15	0.084	Human Rat
Lmo4	LIM domain only 4	0.084
Sart3	squamous cell carcinoma antigen recognized by T-cells 3	0.084
Mark3	MAP/microtubule affinity-regulating kinase 3	0.084	Rat
Mgll	monoglyceride lipase	0.084
Myo9a	myosin IXA	0.084
Efnb1	ephrin B1	0.084
Gpx3	glutathione peroxidase 3	0.084
Stat4	signal transducer and activator of transcription 4	0.084	Rat
Cxcr7	chemokine (C-X-C motif) receptor 7	0.084
Gpr85	G protein-coupled receptor 85	0.084
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.084
Cdc42ep3	CDC42 effector protein (Rho GTPase binding) 3	0.084
Pctk1	PCTAIRE protein kinase 1	0.084
Tob2	transducer of ERBB2, 2	0.084
Myf6	myogenic factor 6	0.084	Mouse
Map2k6	mitogen-activated protein kinase kinase 6	0.084
Nono	non-POU domain containing, octamer-binding	0.084	Mouse
Rab10	RAB10, member RAS oncogene family	0.084
Ddit4	DNA-damage-inducible transcript 4	0.084
Cryba1	crystallin, beta A1	0.084
Psen2	presenilin 2	0.084
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.084	Rat Fly
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.084
Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.084
Pthlh	parathyroid hormone-like hormone	0.083
Pax6	paired box 6	0.083	Mouse Rat
Ldha	lactate dehydrogenase A	0.083
A2m	alpha-2-macroglobulin	0.083
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.083
Adm	adrenomedullin	0.083
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.083
Fam3b	family with sequence similarity 3, member B	0.083
Ankle2	ankyrin repeat and LEM domain containing 2	0.083
Ltk	leukocyte receptor tyrosine kinase	0.083
Nup155	nucleoporin 155	0.083
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.083
Mcm6	minichromosome maintenance complex component 6	0.083
Khsrp	KH-type splicing regulatory protein	0.082
Sh2b1	SH2B adaptor protein 1	0.082
Ier3	immediate early response 3	0.082
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.082
Klf12	Kruppel-like factor 12	0.082
Flna	filamin A, alpha	0.082
RGD1307722	similar to hypothetical protein MGC20700	0.082
Mafg	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.082
Aurkb	aurora kinase B	0.082	Human
LOC313672	kazrin	0.082
Dll1	delta-like 1 (Drosophila)	0.082
Mag	myelin-associated glycoprotein	0.082
Clps	colipase, pancreatic	0.082
Pitx2	paired-like homeodomain 2	0.082	Human
Sox7	SRY (sex determining region Y)-box 7	0.082	Human Rat Fly
Impdh2	IMP (inosine monophosphate) dehydrogenase 2	0.081
Foxa1	forkhead box A1	0.081
Lphn1	latrophilin 1	0.081
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.081
Clec4f	C-type lectin domain family 4, member f	0.081
Strn4	striatin, calmodulin binding protein 4	0.081	Rat
Ptgs2	prostaglandin-endoperoxide synthase 2	0.081
Tars	threonyl-tRNA synthetase	0.081
Hapln2	hyaluronan and proteoglycan link protein 2	0.081
Glg1	golgi apparatus protein 1	0.081
Mobp	myelin-associated oligodendrocyte basic protein	0.081
Psd4	pleckstrin and Sec7 domain containing 4	0.081
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.081
Grin2d	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.080
Sfrs12	splicing factor, arginine/serine-rich 12	0.080	Worm
Lad1	ladinin 1	0.080
Nfic	nuclear factor I/C	0.080
Znf692	zinc finger protein 692	0.080
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.080
Slc28a3	solute carrier family 28 (sodium-coupled nucleoside transporter), member 3	0.080
Foxc2	forkhead box C2	0.080
Nkx6-1	NK6 homeobox 1	0.080
Aqp9	aquaporin 9	0.080
Agtr1b	angiotensin II receptor, type 1b	0.080	Rat
Prpf3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.080
Rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.079
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.079
Cp	ceruloplasmin	0.079
Tulp1	tubby like protein 1	0.079
Rxra	retinoid X receptor alpha	0.079	Human Mouse Rat Worm
Tpm3	tropomyosin 3, gamma	0.079
Mllt3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	0.079
Herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.079
Exoc5	exocyst complex component 5	0.079
Pcbp2	poly(rC) binding protein 2	0.079
Cpd	carboxypeptidase D	0.078
Ccl11	chemokine (C-C motif) ligand 11	0.078
Zwint	ZW10 interactor	0.078
Lmnb1	lamin B1	0.078	Fly
H2afx	H2A histone family, member X	0.078
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.078
Osbpl1a	oxysterol binding protein-like 1A	0.078
Dnaja4	DnaJ (Hsp40) homolog, subfamily A, member 4	0.077
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.077
Ebf1	early B-cell factor 1	0.077
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.077
Qars	glutaminyl-tRNA synthetase	0.077
Pdgfb	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.077	Human
Tcof1	Treacher Collins-Franceschetti syndrome 1 homolog (human)	0.077
Otud5	OTU domain containing 5	0.077
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.077
C1r	complement component 1, r subcomponent	0.077
Bcl2	B-cell CLL/lymphoma 2	0.077	Zebrafish Rat
Pyy	peptide YY (mapped)	0.077
Diaph1	diaphanous homolog 1 (Drosophila)	0.077
Braf	v-raf murine sarcoma viral oncogene homolog B1	0.077
Vom1r97	vomeronasal 1 receptor 97	0.077
Marcksl1	MARCKS-like 1	0.077
Ppp1r3b	protein phosphatase 1, regulatory (inhibitor) subunit 3B	0.077	Yeast
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.077
Anapc5	anaphase-promoting complex subunit 5	0.077
Bhlhe40	basic helix-loop-helix family, member e40	0.077
Bdkrb2	bradykinin receptor B2	0.077
Fgfr1	Fibroblast growth factor receptor 1	0.077	Mouse
Vamp3	vesicle-associated membrane protein 3	0.076
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.076
Dusp5	dual specificity phosphatase 5	0.076
Shc3	SHC (Src homology 2 domain containing) transforming protein 3	0.076
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.076
Ccdc102a	coiled-coil domain containing 102A	0.076
Smarcd2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	0.076
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.076
Epor	erythropoietin receptor	0.076
Lyz2	lysozyme 2	0.076
Carhsp1	calcium regulated heat stable protein 1	0.075
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.075
Efemp1	EGF-containing fibulin-like extracellular matrix protein 1	0.075
Hmg20a	high mobility group 20A	0.075	Mouse
Rhag	Rh-associated glycoprotein	0.075
Ifrd1	interferon-related developmental regulator 1	0.075
Psmc1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.075
Cast	calpastatin	0.075
Kcnk12	potassium channel, subfamily K, member 12	0.075
Hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	0.075
Glra1	glycine receptor, alpha 1	0.075
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.075
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.075
Ankrd40	ankyrin repeat domain 40	0.075
Ciita	class II, major histocompatibility complex, transactivator	0.075
Eif4b	eukaryotic translation initiation factor 4B	0.075
Syt3	synaptotagmin III	0.075
Wdr26	WD repeat domain 26	0.074
Sec31a	SEC31 homolog A (S. cerevisiae)	0.074
St18	suppression of tumorigenicity 18	0.074
Zfp364	zinc finger protein 364	0.074
Tuba1c	tubulin, alpha 1C	0.074
Lrrn2	leucine rich repeat neuronal 2	0.074
Smad3	SMAD family member 3	0.074
Kif1c	kinesin family member 1C	0.074
Dbn1	drebrin 1	0.074
Psmd13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.074
Prkci	protein kinase C, iota	0.074
Slc4a11	solute carrier family 4, sodium borate transporter, member 11	0.074
Npy	neuropeptide Y	0.074
Mecp2	methyl CpG binding protein 2	0.074
Dctn4	dynactin 4	0.074
Sh3kbp1	SH3-domain kinase binding protein 1	0.074
Dock8	dedicator of cytokinesis 8	0.074
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.074	Rat
Ccne1	cyclin E1	0.074	Fly
Hdac1	histone deacetylase 1	0.073
Lrrc59	leucine rich repeat containing 59	0.073
Traf4	Tnf receptor associated factor 4	0.073
Capg	capping protein (actin filament), gelsolin-like	0.073
Fabp5	fatty acid binding protein 5, epidermal	0.073
Dcaf8	DDB1 and CUL4 associated factor 8	0.073
Tyms	thymidylate synthetase	0.073
Gzmf	granzyme F	0.073
Kcnq1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.073	Mouse
Lgals2	lectin, galactoside-binding, soluble, 2	0.073
Cd4	Cd4 molecule	0.073
Nf1	neurofibromin 1	0.073	Mouse
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.073
Snrpb	small nuclear ribonucleoprotein polypeptides B and B1	0.073
Fnta	farnesyltransferase, CAAX box, alpha	0.073
Odf3b	outer dense fiber of sperm tails 3B	0.073
Apoa1	apolipoprotein A-I	0.073
LOC60591	calcium-activated potassium channel beta subunit	0.073
Tbl1xr1	transducin (beta)-like 1 X-linked receptor 1	0.072
Pnliprp2	pancreatic lipase-related protein 2	0.072
Ripk3	receptor-interacting serine-threonine kinase 3	0.072
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.072
RGD1564093	similar to RIKEN cDNA 2310036O22	0.072
Phf2	PHD finger protein 2	0.072
Cfi	complement factor I	0.072
Mepce	methylphosphate capping enzyme	0.072
Arhgap25	Rho GTPase activating protein 25	0.072
Abcc9	ATP-binding cassette, subfamily C (CFTR/MRP), member 9	0.072
Fabp1	fatty acid binding protein 1, liver	0.071	Human
Ralbp1	ralA binding protein 1	0.071
Prc1	protein regulator of cytokinesis 1	0.071
Ier5l	immediate early response 5-like	0.071
Pdzk1ip1	PDZK1 interacting protein 1	0.071