IMP: Integrative Multi-species Prediction

Rattus norvegicus

1 genes annotated in rat

sorbitol biosynthetic process

The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.

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In addition to gene-name show these genes:

Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sorbitol biosynthetic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "sorbitol biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Mgst2	microsomal glutathione S-transferase 2	0.267
Tuba1c	tubulin, alpha 1C	0.249
Psmb5	proteasome (prosome, macropain) subunit, beta type 5	0.207
Pgam1	phosphoglycerate mutase 1 (brain)	0.154
Oaz1	ornithine decarboxylase antizyme 1	0.136
Rplp2	ribosomal protein, large P2	0.126
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.118
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.101
Dapk3	death-associated protein kinase 3	0.076
Rpn1	ribophorin I	0.076
Pparg	peroxisome proliferator-activated receptor gamma	0.067
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.061
Slc35b1	solute carrier family 35, member B1	0.057
Anxa2	annexin A2	0.056
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.049
Akr1c12	aldo-keto reductase family 1, member C12	0.046	Rat
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.046
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.042
Adh1	alcohol dehydrogenase 1 (class I)	0.036
LOC362855	P55	0.035
Mup5	major urinary protein 5	0.035
Fabp12	fatty acid binding protein 12	0.034
Anks4b	ankyrin repeat and sterile alpha motif domain containing 4B	0.031
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.030
Prdx2	peroxiredoxin 2	0.029
Nat1	N-acetyltransferase 1	0.029
Pdzk1	PDZ domain containing 1	0.029
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.028
Rnf207	ring finger protein 207	0.027
Ghr	growth hormone receptor	0.027
Acmsd	aminocarboxymuconate semialdehyde decarboxylase	0.026
Ephx1	epoxide hydrolase 1, microsomal	0.025
Slc17a3	solute carrier family 17 (sodium phosphate), member 3	0.023
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.023
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.022
As3mt	arsenic (+3 oxidation state) methyltransferase	0.022
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.022
LOC688473	similar to 40S ribosomal protein S2	0.021
G6pd	glucose-6-phosphate dehydrogenase	0.021
Fmo2	flavin containing monooxygenase 2	0.021
Il15	interleukin 15	0.021
Sult2al1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1	0.020
Gsta5	glutathione S-transferase Yc2 subunit	0.019
Hint3	histidine triad nucleotide binding protein 3	0.019
Akr1c19	aldo-keto reductase family 1, member C19	0.019	Rat
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.019
Akr1c14	aldo-keto reductase family 1, member C14	0.019	Rat
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.018
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.018
Dpm2	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit	0.018
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.018
Cd36	CD36 molecule (thrombospondin receptor)	0.018
Ftl	ferritin, light polypeptide	0.017
Nat8	N-acetyltransferase 8	0.017
Tas2r105	taste receptor, type 2, member 105	0.017
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.016
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.016
Lrat	lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)	0.016
Cyp2j4	cytochrome P450, family 2, subfamily j, polypeptide 4	0.016
Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C	0.015
Slc40a1	solute carrier family 39 (iron-regulated transporter), member 1	0.015
Bphl	biphenyl hydrolase-like (serine hydrolase)	0.015
Sdhc	succinate dehydrogenase complex, subunit C, integral membrane protein	0.014
Cyb5a	cytochrome b5 type A (microsomal)	0.014
Tmem66	transmembrane protein 66	0.014
Prl7a4	prolactin family 7, subfamily a, member 4	0.014
Gpx4	glutathione peroxidase 4	0.014
Ppia	peptidylprolyl isomerase A (cyclophilin A)	0.013
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.013
LOC100360843	ribosomal protein S19-like	0.013
Pbld	phenazine biosynthesis-like protein domain containing	0.013
Otc	ornithine carbamoyltransferase	0.013
Shroom1	shroom family member 1	0.012
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.012
UST4r	integral membrane transport protein UST4r	0.012
Calm1	calmodulin 1	0.012
Ces1c	carboxylesterase 1C	0.012
Pex11a	peroxisomal biogenesis factor 11 alpha	0.012
Aadac	arylacetamide deacetylase (esterase)	0.012
Sult1e1	sulfotransferase family 1E, estrogen-preferring, member 1	0.012
Cat	catalase	0.011
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.011
Mrpl16	mitochondrial ribosomal protein L16	0.011
Bche	butyrylcholinesterase	0.011
Akr1cl1	aldo-keto reductase family 1, member C-like 1	0.011	Rat
Kif16b	kinesin family member 16B	0.010
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.010
Otud1	OTU domain containing 1	0.010
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.010
Hmox1	heme oxygenase (decycling) 1	0.010
Rbp7	retinol binding protein 7, cellular	0.010
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.010