IMP: Integrative Multi-species Prediction

Rattus norvegicus

12 genes annotated in rat

regulation of cell killing

Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in ratInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell killing"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of cell killing" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-EC2	RT1 class Ib, locus EC2	0.983
Cxcl10	chemokine (C-X-C motif) ligand 10	0.586
RT1-CE12	RT1 class I, locus CE12	0.556
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.410
Gzmb	granzyme B	0.408
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.287
Mmp12	matrix metallopeptidase 12	0.238
Hsph1	heat shock 105/110 protein 1	0.203
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.201
Gzmk	granzyme K	0.192
Nkg7	natural killer cell group 7 sequence	0.189
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.121
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.120
Neurl3	neuralized homolog 3 (Drosophila)	0.093
RT1-S3	RT1 class Ib, locus S3	0.089	Mouse Rat
Mcpt8	mast cell protease 8	0.086
Il2rb	interleukin 2 receptor, beta	0.082
Sell	selectin L	0.080
Cd247	Cd247 molecule	0.076
Ccl5	chemokine (C-C motif) ligand 5	0.074
Ccl4	chemokine (C-C motif) ligand 4	0.073
Il7r	interleukin 7 receptor	0.066
LOC100364500	RT1 class I, locus CE11-like	0.062
Il1b	interleukin 1 beta	0.059
Hspb1	heat shock protein 1	0.058
Ccl2	chemokine (C-C motif) ligand 2	0.058
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.057
Atf3	activating transcription factor 3	0.054
LOC100364485	mCG1051031-like	0.053
RT1-Cl	RT1 class Ib, locus Cl	0.047
Ccr2	chemokine (C-C motif) receptor 2	0.046
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.046
Igsf6	immunoglobulin superfamily, member 6	0.043
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.042	Rat
Spn	sialophorin	0.041
Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	0.040
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.038	Rat
RT1-N3	RT1 class Ib, locus N3	0.038	Rat
Casp1	caspase 1	0.036
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.036
Gimap4	GTPase, IMAP family member 4	0.035
Prf1	perforin 1 (pore forming protein)	0.034
Ubb	ubiquitin B	0.033
Ccl7	chemokine (C-C motif) ligand 7	0.032
Cd2	Cd2 molecule	0.031
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.031	Rat
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.031
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.031
Cd8a	CD8a molecule	0.030
Fut2	fucosyltransferase 2 (secretor status included)	0.029
Ccl3	chemokine (C-C motif) ligand 3	0.029
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.028
Cd53	Cd53 molecule	0.028
Dnaja4	DnaJ (Hsp40) homolog, subfamily A, member 4	0.027
Il6	interleukin 6	0.026
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.024
Gzma	granzyme A	0.024
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.024
Xcl1	chemokine (C motif) ligand 1	0.023	Human
Ccr5	chemokine (C-C motif) receptor 5	0.023
Cd14	CD14 molecule	0.022
Dcaf7	DDB1 and CUL4 associated factor 7	0.022
LOC300024	similar to Ly6-B antigen gene	0.022
Oas1a	2'-5' oligoadenylate synthetase 1A	0.021
Gbp2	guanylate binding protein 2	0.021
Fth1	ferritin, heavy polypeptide 1	0.021
Cxcr4	chemokine (C-X-C motif) receptor 4	0.020
RT1-Ba	RT1 class II, locus Ba	0.020
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.020
Csf1	colony stimulating factor 1 (macrophage)	0.020
RGD1562844	similar to serine (or cysteine) proteinase inhibitor, clade B, member 9	0.020
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.019	Human
Irf1	interferon regulatory factor 1	0.019
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.019	Mouse
Tfec	transcription factor EC	0.019
Slfn2	schlafen 2	0.019
Tlr7	toll-like receptor 7	0.019
Zap70	zeta-chain (TCR) associated protein kinase	0.019
Plaur	plasminogen activator, urokinase receptor	0.019
RT1-CE16	RT1 class I, locus CE16	0.018
Junb	jun B proto-oncogene	0.018
Mmp7	matrix metallopeptidase 7	0.017
Clec9a	C-type lectin domain family 9, member a	0.015	Rat
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.014
Plcg2	phospholipase C, gamma 2	0.014
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.014
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.014
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.014	Human Mouse Rat
Lyz2	lysozyme 2	0.014
Rhoh	ras homolog gene family, member H	0.014
Mapk3	mitogen activated protein kinase 3	0.013
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.013
Irf2	interferon regulatory factor 2	0.013
Sele	selectin E	0.012
Rgs1	regulator of G-protein signaling 1	0.012
Ubd	ubiquitin D	0.012
Golph3	golgi phosphoprotein 3 (coat-protein)	0.011
Itm2b	integral membrane protein 2B	0.011
Cetn2	centrin, EF-hand protein, 2	0.011
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.011
Tnfrsf26	tumor necrosis factor receptor superfamily, member 26	0.011
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.011	Mouse
Epsti1	epithelial stromal interaction 1 (breast)	0.011
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.011
LOC100363783	rCG53773-like	0.011
Cxcl9	chemokine (C-X-C motif) ligand 9	0.010
Parvg	parvin, gamma	0.010
Capn5	calpain 5	0.010
Batf	basic leucine zipper transcription factor, ATF-like	0.010
Prkcb	protein kinase C, beta	0.010