IMP: Integrative Multi-species Prediction

Rattus norvegicus

3 genes annotated in rat

Multi-species View

regulation of interleukin 1 beta secretion

GO:0050706

Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 1 beta secretion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of interleukin 1 beta secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Ptprc	protein tyrosine phosphatase, receptor type, C	0.632
Casp1	caspase 1	0.620
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.591
Cybb	cytochrome b-245, beta polypeptide	0.378
Cd53	Cd53 molecule	0.377
Pdcl	phosducin-like	0.364
Casp8	caspase 8	0.300	Rat
A3galt2	alpha 1,3-galactosyltransferase 2	0.288
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.266
Casp2	caspase 2	0.244	Rat
Casp3	caspase 3	0.230	Rat
Tlr4	toll-like receptor 4	0.228
Akr1c14	aldo-keto reductase family 1, member C14	0.227
Clec4a3	C-type lectin domain family 4, member a3	0.176
Cd38	CD38 molecule	0.157
Parp14	poly (ADP-ribose) polymerase family, member 14	0.153
Ms4a11	membrane-spanning 4-domains, subfamily A, member 11	0.149
Cdc23	CDC23 (cell division cycle 23, yeast, homolog)	0.148
Ctsc	cathepsin C	0.147
Cd48	Cd48 molecule	0.141
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.119
Skap2	src kinase associated phosphoprotein 2	0.113
Nmi	N-myc (and STAT) interactor	0.113
Cdk2	cyclin dependent kinase 2	0.112
Casp12	caspase 12	0.104	Rat
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.103
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.099
Calcrl	calcitonin receptor-like	0.096
Nat1	N-acetyltransferase 1	0.090
Glipr1	GLI pathogenesis-related 1	0.090
Apol3	apolipoprotein L, 3	0.087
Snx6	sorting nexin 6	0.081
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.081
Adam17	ADAM metallopeptidase domain 17	0.079
Gabre	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.076
Adam10	ADAM metallopeptidase domain 10	0.076
Gbp2	guanylate binding protein 2	0.068
Casp6	caspase 6	0.065	Rat
Igsf6	immunoglobulin superfamily, member 6	0.064
Olfml2b	olfactomedin-like 2B	0.062
Cnot6	CCR4-NOT transcription complex, subunit 6	0.059
Kremen1	kringle containing transmembrane protein 1	0.058
S1pr2	sphingosine-1-phosphate receptor 2	0.056
Apaf1	apoptotic peptidase activating factor 1	0.056
Caprin1	cell cycle associated protein 1	0.055
Aif1	allograft inflammatory factor 1	0.053
Adar	adenosine deaminase, RNA-specific	0.052
Shmt1	serine hydroxymethyltransferase 1 (soluble)	0.052
Nras	neuroblastoma ras oncogene	0.051
Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.050
Ets1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.048
Toe1	target of EGR1, member 1 (nuclear)	0.048
Lig3	ligase III, DNA, ATP-dependent	0.046
Ocln	occludin	0.046
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.044
Cp	ceruloplasmin	0.043
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.043
Xiap	X-linked inhibitor of apoptosis	0.040
Plau	plasminogen activator, urokinase	0.037
Mpeg1	macrophage expressed 1	0.036
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.036
Znf532	zinc finger protein 532	0.035
Jak1	Janus kinase 1	0.035
RT1-Bb	RT1 class II, locus Bb	0.035
Dhfr	dihydrofolate reductase	0.035
Bdkrb2	bradykinin receptor B2	0.034
Pdia4	protein disulfide isomerase family A, member 4	0.034
Tgfbr2	transforming growth factor, beta receptor II	0.033
Rnf4	ring finger protein 4	0.031
Freq	frequenin homolog (Drosophila)	0.031
Myo1b	myosin Ib	0.031
Cd44	Cd44 molecule	0.028
Exoc7	exocyst complex component 7	0.028
Casp7	caspase 7	0.028	Rat
Serpini2	serine (or cysteine) peptidase inhibitor, clade I, member 2	0.027
Hspa12b	heat shock protein 12B	0.027
Gper	G protein-coupled estrogen receptor 1	0.025
Ucn	urocortin	0.024
Arl11	ADP-ribosylation factor-like 11	0.024
Syt9	synaptotagmin IX	0.024
Calcr	calcitonin receptor	0.024
Pter	phosphotriesterase related	0.024
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.023
Ccr5	chemokine (C-C motif) receptor 5	0.022
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.022
Sec22a	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	0.022
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.022
RT1-N3	RT1 class Ib, locus N3	0.022
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.021
Nmnat2	nicotinamide nucleotide adenylyltransferase 2	0.021
Cd47	Cd47 molecule	0.021
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.020
Creb1	cAMP responsive element binding protein 1	0.020
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.020
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.020
Rab32	RAB32, member RAS oncogene family	0.019
siat7D	alpha-2,6-sialyltransferase ST6GalNAc IV	0.019
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.019
Catsper2	cation channel, sperm associated 2	0.019
Cd200r1	CD200 receptor 1	0.018
LOC64038	sertolin	0.018
Olr1271	olfactory receptor 1271	0.018
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.018
Ahr	aryl hydrocarbon receptor	0.018
Cxcl13	chemokine (C-X-C motif) ligand 13	0.018
Msn	moesin	0.017
Glp2r	glucagon-like peptide 2 receptor	0.017
Il1b	interleukin 1 beta	0.017
Accn3	amiloride-sensitive cation channel 3	0.017
Stat1	signal transducer and activator of transcription 1	0.017
Zfp260	zinc finger protein 260	0.017
Podxl	podocalyxin-like	0.017
Slfn2	schlafen 2	0.016
Mmp12	matrix metallopeptidase 12	0.016
Amelx	amelogenin X chromosome	0.016
Leprot	leptin receptor overlapping transcript	0.016
Lbr	lamin B receptor	0.016
Crot	carnitine O-octanoyltransferase	0.016
Trim5	tripartite motif-containing 5	0.016
Hoxa1	homeo box A1	0.016
Gnb4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.016
Smpx	small muscle protein, X-linked	0.015
Csrnp2	cysteine-serine-rich nuclear protein 2	0.015
Fgf10	fibroblast growth factor 10	0.015
Ifi204	interferon activated gene 204	0.015
RGD1306404	similar to mKIAA1402 protein	0.015
Hoxa4	homeo box A4	0.015
Lim2	lens intrinsic membrane protein 2	0.015
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.015
Ly86	lymphocyte antigen 86	0.015
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.015
LOC100365904	hypothetical protein LOC100365904	0.015
Cyb5r1	cytochrome b5 reductase 1	0.015
Ung	uracil-DNA glycosylase	0.014
Cd4	Cd4 molecule	0.014
Wdr7	WD repeat domain 7	0.014
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.014
Pde11a	phosphodiesterase 11A	0.014
Rab38	RAB38, member RAS oncogene family	0.014
Hsp90b1	heat shock protein 90, beta, member 1	0.014
Foxc1	forkhead box C1	0.014
Dhrs7c	dehydrogenase/reductase (SDR family) member 7C	0.013
Ifih1	interferon induced with helicase C domain 1	0.013
Slfn8	schlafen 8	0.013
Lpar6	lysophosphatidic acid receptor 6	0.013
Ifnar1	interferon (alpha, beta and omega) receptor 1	0.013
Serpinb9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.013
Folr2	folate receptor 2 (fetal)	0.013
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.013
Clecsf6	C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6	0.013
C3ar1	complement component 3a receptor 1	0.013
Grin3b	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	0.013
Laptm5	lysosomal protein transmembrane 5	0.013
Csnk1g3	casein kinase 1, gamma 3	0.013
Secisbp2	SECIS binding protein 2	0.012
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.012
G3bp2	GTPase activating protein (SH3 domain) binding protein 2	0.012
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.012
Prcp	prolylcarboxypeptidase (angiotensinase C)	0.012
Acsm5	acyl-CoA synthetase medium-chain family member 5	0.012
Ctsq	cathepsin Q	0.012
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.012
Npepl1	aminopeptidase-like 1	0.012
RGD1564664	similar to LOC387763 protein	0.012
Hspg2	heparan sulfate proteoglycan 2	0.012
Pdgfd	platelet-derived growth factor, D polypeptide	0.012
Coro1b	coronin, actin-binding protein, 1B	0.012
Rabep2	rabaptin, RAB GTPase binding effector protein 2	0.012
Il7r	interleukin 7 receptor	0.011
Acsl5	acyl-CoA synthetase long-chain family member 5	0.011
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.011
Mmp19	matrix metallopeptidase 19	0.011
Psen1	presenilin 1	0.011
Parp9	poly (ADP-ribose) polymerase family, member 9	0.011
Srgn	serglycin	0.011
Mr1	major histocompatibility complex, class I-related	0.011
RGD1309594	similar to RIKEN cDNA 1810043G02; DNA segment, Chr 10, Johns Hopkins University 13, expressed	0.011
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.011
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.011	Rat
Cxcl9	chemokine (C-X-C motif) ligand 9	0.011
Pls3	plastin 3 (T-isoform)	0.011
Galntl1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1	0.011
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.011
Jub	jub, ajuba homolog (Xenopus laevis)	0.011
Vamp1	vesicle-associated membrane protein 1	0.011
Frk	fyn-related kinase	0.011
Lmo2	LIM domain only 2	0.011
Irx1	iroquois homeobox 1	0.011
Tpm4	tropomyosin 4	0.010
Kcnk3	potassium channel, subfamily K, member 3	0.010
Gfra2	GDNF family receptor alpha 2	0.010
Mocs3	molybdenum cofactor synthesis 3	0.010
Tbxa2r	thromboxane A2 receptor	0.010
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.010
Palb2	partner and localizer of BRCA2	0.010
Mmp8	matrix metallopeptidase 8	0.010
Ucn2	urocortin 2	0.010