IMP: Integrative Multi-species Prediction

Rattus norvegicus

3 genes annotated in rat

Multi-species View

interleukin 1 beta secretion

GO:0050702

The regulated release of interleukin 1 beta from a cell.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 1 beta secretion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "interleukin 1 beta secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.654
Tlr4	toll-like receptor 4	0.494
Nat1	N-acetyltransferase 1	0.383
Cybb	cytochrome b-245, beta polypeptide	0.344
Ptprc	protein tyrosine phosphatase, receptor type, C	0.327
Casp1	caspase 1	0.283
RT1-Da	RT1 class II, locus Da	0.220
Nras	neuroblastoma ras oncogene	0.177
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.158
Akr1c14	aldo-keto reductase family 1, member C14	0.147
Calcrl	calcitonin receptor-like	0.129
RT1-Db1	RT1 class II, locus Db1	0.122
Pdcl	phosducin-like	0.122
Plau	plasminogen activator, urokinase	0.113
A3galt2	alpha 1,3-galactosyltransferase 2	0.113
Ctsc	cathepsin C	0.111
Csf1	colony stimulating factor 1 (macrophage)	0.106
Adam17	ADAM metallopeptidase domain 17	0.106
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.099
Ets1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.090
Cdk2	cyclin dependent kinase 2	0.089
S1pr2	sphingosine-1-phosphate receptor 2	0.083
Cd38	CD38 molecule	0.078
Casp2	caspase 2	0.077	Rat
Gabre	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.074
Ocln	occludin	0.072
Cd53	Cd53 molecule	0.071
RT1-N3	RT1 class Ib, locus N3	0.070
Fgfr2	fibroblast growth factor receptor 2	0.063
Mmp3	matrix metallopeptidase 3	0.058
Dock8	dedicator of cytokinesis 8	0.056
Casp3	caspase 3	0.055	Rat
Casp8	caspase 8	0.054	Rat
Cd48	Cd48 molecule	0.050
Skap2	src kinase associated phosphoprotein 2	0.048
Ms4a11	membrane-spanning 4-domains, subfamily A, member 11	0.046
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.044
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.041
Cd47	Cd47 molecule	0.040
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.038
Accn3	amiloride-sensitive cation channel 3	0.038
RT1-Bb	RT1 class II, locus Bb	0.037
Cdc23	CDC23 (cell division cycle 23, yeast, homolog)	0.037
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.037
Cd44	Cd44 molecule	0.037
Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.035
Aif1	allograft inflammatory factor 1	0.035
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.035
Pdia4	protein disulfide isomerase family A, member 4	0.032
siat7D	alpha-2,6-sialyltransferase ST6GalNAc IV	0.031
Tmpo	thymopoietin	0.031
Elf1	E74-like factor 1	0.030
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.030
Dhfr	dihydrofolate reductase	0.030
Apaf1	apoptotic peptidase activating factor 1	0.029
Igsf6	immunoglobulin superfamily, member 6	0.029
Calcr	calcitonin receptor	0.028
Sec22a	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	0.028
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.028
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.027
Bdkrb2	bradykinin receptor B2	0.025
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.025
Casp6	caspase 6	0.025	Rat
RGD1564664	similar to LOC387763 protein	0.025
Crot	carnitine O-octanoyltransferase	0.025
Casp7	caspase 7	0.025	Rat
Fam198b	family with sequence similarity 198, member B	0.024
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.024
Il1a	interleukin 1 alpha	0.024
Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.024
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.023
RT1-Ba	RT1 class II, locus Ba	0.023
Abcg3l1	ATP-binding cassette, subfamily G (WHITE), member 3-like 1	0.021
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.021
Ptprh	protein tyrosine phosphatase, receptor type, H	0.021
Slc22a25	solute carrier family 22, member 25	0.020
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.019
Bmpr1a	bone morphogenetic protein receptor, type IA	0.019
Psen1	presenilin 1	0.018
Cxcl10	chemokine (C-X-C motif) ligand 10	0.018
RGD1307254	similar to RIKEN cDNA 1200011I18	0.018
Rpa2	replication protein A2	0.018
Mmp12	matrix metallopeptidase 12	0.018
Parp14	poly (ADP-ribose) polymerase family, member 14	0.018
Leprot	leptin receptor overlapping transcript	0.017
Cnot6	CCR4-NOT transcription complex, subunit 6	0.017
Adar	adenosine deaminase, RNA-specific	0.017
Actc1	actin, alpha, cardiac muscle 1	0.017
Tgfbr2	transforming growth factor, beta receptor II	0.017
Lig3	ligase III, DNA, ATP-dependent	0.017
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.016
Exoc7	exocyst complex component 7	0.016
Pctp	phosphatidylcholine transfer protein	0.016
Vcam1	vascular cell adhesion molecule 1	0.016
Socs3	suppressor of cytokine signaling 3	0.016
Gnb4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.015
Pde11a	phosphodiesterase 11A	0.015
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.015	Rat
Tfpi	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.015
Lmo2	LIM domain only 2	0.015
Vcan	versican	0.015
Fgl2	fibrinogen-like 2	0.015
Foxc1	forkhead box C1	0.015
Mocos	molybdenum cofactor sulfurase	0.015
Dynlt1	dynein light chain Tctex-type 1	0.014
Grin3b	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	0.014
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.014
Enpep	glutamyl aminopeptidase	0.014
Syt9	synaptotagmin IX	0.014
Sec1	secretory blood group 1	0.014
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.014
Ube2i	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.014
Ccl2	chemokine (C-C motif) ligand 2	0.014
Atp2c1	ATPase, Ca++ transporting, type 2C, member 1	0.014
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.014
Cd14	CD14 molecule	0.014
Cd86	CD86 molecule	0.014
Catsper2	cation channel, sperm associated 2	0.014
Omp	olfactory marker protein	0.014
Grm4	glutamate receptor, metabotropic 4	0.014
Adra2b	adrenergic, alpha-2B-, receptor	0.013
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.013
Oprl1	opiate receptor-like 1	0.013
Cd4	Cd4 molecule	0.013
Kitlg	KIT ligand	0.013
Cald1	caldesmon 1	0.013
Ifih1	interferon induced with helicase C domain 1	0.013
Mmp8	matrix metallopeptidase 8	0.013
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.013
Casp12	caspase 12	0.013	Rat
Kdelc1	KDEL (Lys-Asp-Glu-Leu) containing 1	0.013
Rab20	RAB20, member RAS oncogene family	0.012
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.012
Mpeg1	macrophage expressed 1	0.012
Cckbr	cholecystokinin B receptor	0.012
Toe1	target of EGR1, member 1 (nuclear)	0.012
Fosl1	fos-like antigen 1	0.012
LOC56764	dnaj-like protein	0.012
Edn1	endothelin 1	0.012
Top2a	topoisomerase (DNA) II alpha	0.012
Podxl	podocalyxin-like	0.012
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.012
Trim5	tripartite motif-containing 5	0.012
Sp1	Sp1 transcription factor	0.012
Ccr5	chemokine (C-C motif) receptor 5	0.012
Il33	interleukin 33	0.012
Smad9	SMAD family member 9	0.012
Ung	uracil-DNA glycosylase	0.012
Apol3	apolipoprotein L, 3	0.012
Rbp3	retinol binding protein 3, interstitial	0.011
Gper	G protein-coupled estrogen receptor 1	0.011
Cd200r1	CD200 receptor 1	0.011
Acsl5	acyl-CoA synthetase long-chain family member 5	0.011
Rab38	RAB38, member RAS oncogene family	0.011
Agtr1a	angiotensin II receptor, type 1a	0.011
Lpar6	lysophosphatidic acid receptor 6	0.011
Nradd	neurotrophin receptor associated death domain	0.011
Smad2	SMAD family member 2	0.011
Prcp	prolylcarboxypeptidase (angiotensinase C)	0.011
Pgf	placental growth factor	0.011
Csrnp2	cysteine-serine-rich nuclear protein 2	0.011
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.011
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.011
Nxn	nucleoredoxin	0.011
Cklf	chemokine-like factor	0.010
Dusp6	dual specificity phosphatase 6	0.010
Bet1	blocked early in transport 1 homolog (S. cerevisiae)	0.010
LOC100359879	RIKEN cDNA A830041P22-like	0.010
Fam60a	family with sequence similarity 60, member A	0.010
Nif3l1	NIF3 NGG1 interacting factor 3-like 1 (S. pombe)	0.010
Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	0.010
Frk	fyn-related kinase	0.010
Dcaf17	DDB1 and CUL4 associated factor 17	0.010
Has2	hyaluronan synthase 2	0.010
Ugt1a6	UDP glucuronosyltransferase 1 family, polypeptide A6	0.010