IMP: Integrative Multi-species Prediction

Rattus norvegicus

32 genes annotated in rat

pyridine containing compound metabolic process

The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.

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Known genes in the process in ratInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pyridine containing compound metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "pyridine containing compound metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Pgk1	phosphoglycerate kinase 1	0.829
LOC100363662	6-phosphogluconate dehydrogenase, decarboxylating-like	0.699
Tpi1	triosephosphate isomerase 1	0.669
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.513	Rat
Cyc1	cytochrome c-1	0.465
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.417	Rat
Eno1	enolase 1, (alpha)	0.407
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.398
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.335	Rat
Sult1a1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	0.328
Gnmt	glycine N-methyltransferase	0.289
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.283
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.250
Mdh2	malate dehydrogenase 2, NAD (mitochondrial)	0.220
Atp5c1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.218
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.205	Rat
Gckr	glucokinase (hexokinase 4) regulator	0.205
Otc	ornithine carbamoyltransferase	0.182
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.182
Fmo3	flavin containing monooxygenase 3	0.179
Apob	apolipoprotein B	0.176
Aco2	aconitase 2, mitochondrial	0.160
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.159	Rat
Pgam1	phosphoglycerate mutase 1 (brain)	0.158
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.155	Rat
G6pc	glucose-6-phosphatase, catalytic subunit	0.143
Olr59	olfactory receptor 59	0.129
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.127
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.124
LOC293989	cytochrome P450-like	0.118	Rat
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.114
Tufm	Tu translation elongation factor, mitochondrial	0.111
Uox	urate oxidase	0.107
Prdx3	peroxiredoxin 3	0.106
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.104
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.098
Mtch2	mitochondrial carrier homolog 2 (C. elegans)	0.094
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.092
Slc25a3	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3	0.091
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.091
A1i3	alpha-1-inhibitor III	0.090
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.089
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.088	Rat
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.086
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.086
Gsta2	glutathione S-transferase A2	0.085
Sdhb	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.084
Pon1	paraoxonase 1	0.082
Dpys	dihydropyrimidinase	0.080
Serpina1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.076
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.072
Hpd	4-hydroxyphenylpyruvate dioxygenase	0.071
Ces1c	carboxylesterase 1C	0.071
Nmt1	N-myristoyltransferase 1	0.063
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.061
Pkm2	pyruvate kinase, muscle	0.059
LOC494499	LOC494499 protein	0.059
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.058
Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	0.056
Akr1c18	aldo-keto reductase family 1, member C18	0.056
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.055
Olr1701	olfactory receptor 1701	0.054
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.054
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.052
Gsta5	glutathione S-transferase Yc2 subunit	0.052
Nat8	N-acetyltransferase 8	0.049
Ctsb	cathepsin B	0.048
Dlat	dihydrolipoamide S-acetyltransferase	0.047
Dhfr	dihydrofolate reductase	0.047
Taldo1	transaldolase 1	0.046
Ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.046
Cox5a	cytochrome c oxidase, subunit Va	0.046
Cyp2b2	cytochrome P450, family 2, subfamily b, polypeptide 2	0.044
Sult1e1	sulfotransferase family 1E, estrogen-preferring, member 1	0.044
Atp5b	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.044
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.041
Trap1	TNF receptor-associated protein 1	0.040
Cd151	CD151 molecule (Raph blood group)	0.039
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.039
Tkt	transketolase	0.038
Aldoa	aldolase A, fructose-bisphosphate	0.037
Cyp4f6	cytochrome P450, family 4, subfamily f, polypeptide 6	0.037
Got2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)	0.037
LOC100361864	UDP-glucuronosyltransferase 2B3-like	0.036
Ces1d	carboxylesterase 1D	0.036
Aqp9	aquaporin 9	0.036
F9	coagulation factor IX	0.036
Kynu	kynureninase (L-kynurenine hydrolase)	0.035
Ghrhr	growth hormone releasing hormone receptor	0.034
Slc25a39	solute carrier family 25, member 39	0.034
Fmo1	flavin containing monooxygenase 1	0.033	Human
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.032
Auh	AU RNA binding protein/enoyl-coenzyme A hydratase	0.032
Oplah	5-oxoprolinase (ATP-hydrolysing)	0.032
Khk	ketohexokinase	0.031
Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)	0.031
Rxrg	retinoid X receptor gamma	0.031
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.030
Plg	plasminogen	0.030
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.030
Aadac	arylacetamide deacetylase (esterase)	0.029
Apoa2	apolipoprotein A-II	0.029
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.029
Acsm5	acyl-CoA synthetase medium-chain family member 5	0.029
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.028
Inmt	indolethylamine N-methyltransferase	0.028
Crygf	crystallin, gamma F	0.028
Gstm1	glutathione S-transferase mu 1	0.028
LOC100365112	carboxylesterase-like	0.028
Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	0.027
Akr7a3	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	0.026
RGD1302996	hypothetical protein MGC:15854	0.026
Fdxr	ferredoxin reductase	0.026
Ces1e	carboxylesterase 1E	0.026
Mylk2	myosin light chain kinase 2	0.026
Gss	glutathione synthetase	0.025
Alb	albumin	0.025
Mfn2	mitofusin 2	0.025
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.025
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.025	Rat
Rgn	regucalcin (senescence marker protein-30)	0.024
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.024
Prdx1	peroxiredoxin 1	0.024
Adh1	alcohol dehydrogenase 1 (class I)	0.024
Fasn	fatty acid synthase	0.024
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.024
Vps35	vacuolar protein sorting 35 homolog (S. cerevisiae)	0.023
Ces1f	carboxylesterase 1F	0.023
Klkb1	kallikrein B, plasma 1	0.023
Acads	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	0.023
Glud1	glutamate dehydrogenase 1	0.023
Timm23	translocase of inner mitochondrial membrane 23 homolog (yeast)	0.023
Mbl2	mannose-binding lectin (protein C) 2	0.023
Crnkl1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)	0.023
Slc22a8	solute carrier family 22 (organic anion transporter), member 8	0.023
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.023
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.022
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.022
Fh1	fumarate hydratase 1	0.022
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.021
Gulo	gulonolactone (L-) oxidase	0.021
Aprt	adenine phosphoribosyl transferase	0.021
Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	0.021
Cyp4a2	cytochrome P450, family 4, subfamily a, polypeptide 2	0.021
Fgfr4	fibroblast growth factor receptor 4	0.021
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.021
Idh2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.020
Tmx2	thioredoxin-related transmembrane protein 2	0.019
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.019
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.019
Tas2r126	taste receptor, type 2, member 126	0.019
Hao1	hydroxyacid oxidase (glycolate oxidase) 1	0.019
Dlst	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	0.019
Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)	0.019
Ldhb	lactate dehydrogenase B	0.018
Gstm2	glutathione S-transferase mu 2	0.018
Srxn1	sulfiredoxin 1 homolog (S. cerevisiae)	0.018
Afm	afamin	0.018
Gpi	glucose phosphate isomerase	0.018
Bucs1	butyryl Coenzyme A synthetase 1	0.018
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.018
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.018
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.017
Cyp2s1	cytochrome P450, family 2, subfamily s, polypeptide 1	0.017	Rat
Higd1a	HIG1 hypoxia inducible domain family, member 1A	0.017
C1qbp	complement component 1, q subcomponent binding protein	0.017
Srd5a1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	0.017
Syngr1	synaptogyrin 1	0.017
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.017
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.017
Vps28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.017
Mgst2	microsomal glutathione S-transferase 2	0.016
Mtx2	metaxin 2	0.016
Olr837	olfactory receptor 837	0.016
Pygb	phosphorylase, glycogen; brain	0.016
Ahsg	alpha-2-HS-glycoprotein	0.016
Pon3	paraoxonase 3	0.016
Cps1	carbamoyl-phosphate synthetase 1	0.016
Serpine3	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3	0.016
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.016	Rat
Gstt3	glutathione S-transferase, theta 3	0.016
Anpep	alanyl (membrane) aminopeptidase	0.015
Slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.015
Akr1b8	aldo-keto reductase family 1, member B8	0.015
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.015
Litaf	lipopolysaccharide-induced TNF factor	0.015
Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	0.015
Pdhx	pyruvate dehydrogenase complex, component X	0.015
Fabp1	fatty acid binding protein 1, liver	0.015
Coro1c	coronin, actin binding protein 1C	0.015
Gclc	glutamate-cysteine ligase, catalytic subunit	0.015
Cbs	cystathionine beta synthase	0.015
Acot2	acyl-CoA thioesterase 2	0.015
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.015
Prodh	proline dehydrogenase	0.015
Prelid1	PRELI domain containing 1	0.015
Pitx2	paired-like homeodomain 2	0.015
Higd2a	HIG1 hypoxia inducible domain family, member 2A	0.014
Pfkp	phosphofructokinase, platelet	0.014
Me1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.014
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.014
Fmo2	flavin containing monooxygenase 2	0.014	Human
Pigr	polymeric immunoglobulin receptor	0.014
Ephx1	epoxide hydrolase 1, microsomal	0.014
Slc2a5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.014
Gtf2e2	general transcription factor IIE, polypeptide 2, beta	0.014
Uqcrc1	ubiquinol-cytochrome c reductase core protein I	0.014
Twf1	twinfilin, actin-binding protein, homolog 1 (Drosophila)	0.014
Fabp5	fatty acid binding protein 5, epidermal	0.014
Ppard	peroxisome proliferator-activated receptor delta	0.014
RGD1564114	similar to FLJ46082 protein	0.014
Pck1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.014	Rat
Dnase1l3	deoxyribonuclease 1-like 3	0.014
Dnpep	aspartyl aminopeptidase	0.014
Rims3	regulating synaptic membrane exocytosis 3	0.013
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.013
Mrpl35	mitochondrial ribosomal protein L35	0.013
Mrpl37	mitochondrial ribosomal protein L37	0.013
Tusc5	tumor suppressor candidate 5	0.013
Abcc2	ATP-binding cassette, subfamily C (CFTR/MRP), member 2	0.013
Ust5r	integral membrane transport protein UST5r	0.013
Pnpla2	patatin-like phospholipase domain containing 2	0.013
Lrp2	low density lipoprotein-related protein 2	0.013
Rpusd3	RNA pseudouridylate synthase domain containing 3	0.013
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.013
Ncr1	natural cytotoxicity triggering receptor 1	0.013
Rhd	Rh blood group, D antigen	0.013
Akap14	A kinase (PRKA) anchor protein 14	0.013
Ndufb6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6	0.013
Fam38b	family with sequence similarity 38, member B	0.013
Got1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)	0.013
Pygl	phosphorylase, glycogen, liver	0.013
Pgm1	phosphoglucomutase 1	0.013
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.013
Ldhd	lactate dehydrogenase D	0.013
Retsat	retinol saturase (all trans retinol 13,14 reductase)	0.013
Fam73b	family with sequence similarity 73, member B	0.013
Svs3a	seminal vesicle secretory protein 3A	0.013
Mrpl12	mitochondrial ribosomal protein L12	0.013
Gsr	glutathione reductase	0.012
Igsf1	immunoglobulin superfamily, member 1	0.012
Sdhaf2	succinate dehydrogenase complex assembly factor 2	0.012
LOC691083	hypothetical protein LOC691083	0.012
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.012
Omd	osteomodulin	0.012
Syt3	synaptotagmin III	0.012
Mare	alpha globin regulatory element containing gene	0.012
Spp2	secreted phosphoprotein 2	0.012
Timm17a	translocase of inner mitochondrial membrane 17 homolog A (yeast)	0.012
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.012
Ambp	alpha-1-microglobulin/bikunin precursor	0.012
Mrpl17	mitochondrial ribosomal protein L17	0.012
Hdlbp	high density lipoprotein binding protein	0.012
Akr1c14	aldo-keto reductase family 1, member C14	0.012
Znf575	zinc finger protein 575	0.012
Gng10	guanine nucleotide binding protein (G protein), gamma 10	0.012
Hspb6	heat shock protein, alpha-crystallin-related, B6	0.012
Pdhb	pyruvate dehydrogenase (lipoamide) beta	0.012
Qprt	quinolinate phosphoribosyltransferase	0.012
Setmar	SET domain and mariner transposase fusion gene	0.012
Hadhb	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	0.012
Aldh16a1	aldehyde dehydrogenase 16 family, member A1	0.012
Acaa1b	acetyl-Coenzyme A acyltransferase 1B	0.012
Idh3a	isocitrate dehydrogenase 3 (NAD+) alpha	0.011
Pex1	peroxisomal biogenesis factor 1	0.011
LOC299282	Serine protease inhibitor	0.011
Plbd1	phospholipase B domain containing 1	0.011
Tpcn1	two pore segment channel 1	0.011
Alas1	aminolevulinate, delta-, synthase 1	0.011
Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.011
Ndrg2	N-myc downstream regulated gene 2	0.011
Sstr4	somatostatin receptor 4	0.011
Aqp8	aquaporin 8	0.011
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.011
Cyp2d1	cytochrome P450, family 2, subfamily d, polypeptide 1	0.011
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.011
Bcl2l13	BCL2-like 13 (apoptosis facilitator)	0.011
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.011
Pdcd6	programmed cell death 6	0.011
Hspa14	heat shock protein 14	0.011
Pmpca	peptidase (mitochondrial processing) alpha	0.011
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.011
Klhl25	kelch-like 25 (Drosophila)	0.011
Thra	thyroid hormone receptor alpha	0.011
Tmem97	transmembrane protein 97	0.011
Lamb2	laminin, beta 2	0.011
Hmgcl	3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase	0.011
Phb2	prohibitin 2	0.011
Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.011
Dnah2	dynein, axonemal, heavy chain 2	0.011
RGD1307752	similar to RIKEN cDNA 1110008F13	0.011
Gprc5c	G protein-coupled receptor, family C, group 5, member C	0.011
RT1-M5	RT1 class Ib, locus M5	0.011
Aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.010
Apeh	N-acylaminoacyl-peptide hydrolase	0.010
Nradd	neurotrophin receptor associated death domain	0.010
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	0.010
Rup2	urinary protein 2	0.010
Il1rl2	interleukin 1 receptor-like 2	0.010
Cndp2	CNDP dipeptidase 2 (metallopeptidase M20 family)	0.010
Efemp1	EGF-containing fibulin-like extracellular matrix protein 1	0.010
Acaca	acetyl-coenzyme A carboxylase alpha	0.010
Slc25a11	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	0.010
Gng12	guanine nucleotide binding protein (G protein), gamma 12	0.010
LOC100360501	ribonuclease inhibitor-like	0.010
Gja5	gap junction protein, alpha 5	0.010
Extl1	exostoses (multiple)-like 1	0.010
Tspo	translocator protein	0.010
Miox	myo-inositol oxygenase	0.010
Upb1	ureidopropionase, beta	0.010