IMP
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Rattus norvegicus
0 genes annotated in rat
long qt syndrome
DOID:2843
An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles).
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Inha | inhibin alpha | 0.315 | ||
| Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.295 | ||
| Obscn | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.216 | ||
| Ky | kyphoscoliosis peptidase | 0.195 | ||
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.193 | ||
| Phkg1 | phosphorylase kinase, gamma 1 | 0.148 | ||
| Pgam2 | phosphoglycerate mutase 2 (muscle) | 0.142 | ||
| Pou2f3 | POU class 2 homeobox 3 | 0.121 | ||
| Lrrc14b | leucine rich repeat containing 14B | 0.119 | ||
| Pla2g5 | phospholipase A2, group V | 0.118 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.108 | ||
| Myh6 | myosin, heavy chain 6, cardiac muscle, alpha | 0.106 | ||
| Fgf16 | fibroblast growth factor 16 | 0.105 | ||
| Asph | aspartate-beta-hydroxylase | 0.104 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.101 | ||
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.085 | ||
| Adcy5 | adenylate cyclase 5 | 0.083 | ||
| Nlgn2 | neuroligin 2 | 0.079 | ||
| Rnf207 | ring finger protein 207 | 0.077 | ||
| Trdn | triadin | 0.070 | ||
| Lrrc4b | leucine rich repeat containing 4B | 0.067 | ||
| Neu3 | sialidase 3 (membrane sialidase) | 0.065 | ||
| Rxrg | retinoid X receptor gamma | 0.065 | ||
| Ednra | endothelin receptor type A | 0.059 | ||
| Dchs1 | dachsous 1 (Drosophila) | 0.056 | ||
| Colq | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 0.050 | ||
| Scn5a | sodium channel, voltage-gated, type V, alpha subunit | 0.050 | Human | |
| Pde4a | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 0.048 | ||
| Rimbp2 | RIMS binding protein 2 | 0.045 | ||
| Ckm | creatine kinase, muscle | 0.044 | ||
| Casq2 | calsequestrin 2 (cardiac muscle) | 0.043 | ||
| Akap14 | A kinase (PRKA) anchor protein 14 | 0.038 | ||
| Me3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.037 | ||
| Gja3 | gap junction protein, alpha 3 | 0.037 | ||
| Abcc8 | ATP-binding cassette, subfamily C (CFTR/MRP), member 8 | 0.036 | ||
| Coro6 | coronin 6 | 0.035 | ||
| Asb2 | ankyrin repeat and SOCS box-containing 2 | 0.032 | ||
| Gpsm1 | G-protein signaling modulator 1 (AGS3-like, C. elegans) | 0.032 | ||
| Ttn | titin | 0.031 | ||
| Cdc25a | cell division cycle 25 homolog A (S. pombe) | 0.030 | ||
| Pik3ip1 | phosphoinositide-3-kinase interacting protein 1 | 0.030 | ||
| Tfeb | transcription factor EB | 0.030 | ||
| Kcnh2 | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 0.029 | Human | |
| St3gal3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.028 | ||
| Pfkfb2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.028 | ||
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.028 | ||
| RGD1310269 | hypothetical LOC314472 | 0.028 | ||
| Mare | alpha globin regulatory element containing gene | 0.027 | ||
| Gnb3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 0.027 | ||
| Slc4a3 | solute carrier family 4 (anion exchanger), member 3 | 0.026 | ||
| Prg2 | proteoglycan 2, bone marrow | 0.026 | ||
| Fbxo10 | F-box protein 10 | 0.026 | ||
| Efnb1 | ephrin B1 | 0.026 | ||
| B3gntl1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 | 0.025 | ||
| RGD1306750 | LOC362451 | 0.025 | ||
| Kcna5 | potassium voltage-gated channel, shaker-related subfamily, member 5 | 0.025 | ||
| Cd247 | Cd247 molecule | 0.024 | ||
| Hcn2 | hyperpolarization activated cyclic nucleotide-gated potassium channel 2 | 0.023 | ||
| Scn1b | sodium channel, voltage-gated, type I, beta | 0.023 | ||
| Tsx | testis specific X-linked gene | 0.023 | ||
| Rpl3l | ribosomal protein L3-like | 0.022 | ||
| Pax8 | paired box 8 | 0.022 | ||
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.021 | ||
| Atxn1 | ataxin 1 | 0.021 | ||
| Phyhip | phytanoyl-CoA 2-hydroxylase interacting protein | 0.021 | ||
| Vamp1 | vesicle-associated membrane protein 1 | 0.021 | ||
| Ryr2 | ryanodine receptor 2, cardiac | 0.020 | ||
| Wipf3 | WAS/WASL interacting protein family, member 3 | 0.020 | ||
| Ros1 | c-ros oncogene 1 , receptor tyrosine kinase | 0.020 | ||
| Fam148b | family with sequence similarity 148, member B | 0.020 | ||
| Dspp | dentin sialophosphoprotein | 0.020 | ||
| Rho | rhodopsin | 0.020 | ||
| Tmem171 | transmembrane protein 171 | 0.020 | ||
| Fitm1 | fat storage-inducing transmembrane protein 1 | 0.019 | ||
| P4htm | prolyl 4-hydroxylase, transmembrane | 0.019 | ||
| Tcp11 | t-complex protein 11 | 0.019 | ||
| Tubgcp6 | tubulin, gamma complex associated protein 6 | 0.019 | ||
| RGD1564327 | similar to integrin alpha 8 | 0.019 | ||
| Map1a | microtubule-associated protein 1A | 0.019 | ||
| LOC56764 | dnaj-like protein | 0.018 | ||
| Adra1b | adrenergic, alpha-1B-, receptor | 0.018 | ||
| Cmya5 | cardiomyopathy associated 5 | 0.017 | ||
| RGD1304737 | similar to KIAA1086 protein | 0.017 | ||
| Smg6 | Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) | 0.017 | ||
| Lrrc39 | leucine rich repeat containing 39 | 0.017 | ||
| Catsper2 | cation channel, sperm associated 2 | 0.017 | ||
| Mapt | microtubule-associated protein tau | 0.017 | ||
| Cnga2 | cyclic nucleotide gated channel alpha 2 | 0.017 | ||
| Tcf21 | transcription factor 21 | 0.017 | ||
| Clcnka | chloride channel Ka | 0.017 | ||
| Slc25a29 | solute carrier family 25, member 29 | 0.017 | ||
| LOC689926 | hypothetical protein LOC689926 | 0.016 | ||
| Uncx | UNC homeobox | 0.016 | ||
| Rtn2 | reticulon 2 | 0.016 | ||
| Coq10a | coenzyme Q10 homolog A (S. cerevisiae) | 0.016 | ||
| Ebf1 | early B-cell factor 1 | 0.016 | ||
| Prdm2 | PR domain containing 2, with ZNF domain | 0.016 | ||
| Shbg | sex hormone binding globulin | 0.015 | ||
| Nt5m | 5',3'-nucleotidase, mitochondrial | 0.015 | ||
| Fam63b | family with sequence similarity 63, member B | 0.015 | ||
| Shisa4 | shisa homolog 4 (Xenopus laevis) | 0.015 | ||
| Fn3k | fructosamine 3 kinase | 0.015 | ||
| Rab3b | RAB3B, member RAS oncogene family | 0.015 | ||
| Gng7 | guanine nucleotide binding protein (G protein), gamma 7 | 0.014 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.014 | ||
| Slc12a3 | solute carrier family 12 (sodium/chloride transporters), member 3 | 0.014 | ||
| Bcl2 | B-cell CLL/lymphoma 2 | 0.014 | ||
| Chrnb4 | cholinergic receptor, nicotinic, beta 4 | 0.014 | ||
| Fam83f | family with sequence similarity 83, member F | 0.014 | ||
| Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.013 | Human | |
| Grem1 | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | 0.013 | ||
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.013 | ||
| Neurl2 | neuralized homolog 2 (Drosophila) | 0.013 | ||
| Slc30a2 | solute carrier family 30 (zinc transporter), member 2 | 0.013 | ||
| Krt1 | keratin 1 | 0.013 | ||
| Pygm | phosphorylase, glycogen, muscle | 0.013 | ||
| Rxrb | retinoid X receptor beta | 0.013 | ||
| Ptprn2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.013 | ||
| Alpk3 | alpha-kinase 3 | 0.013 | ||
| Arvcf | armadillo repeat gene deleted in velo-cardio-facial syndrome | 0.013 | ||
| Acacb | acetyl-Coenzyme A carboxylase beta | 0.013 | ||
| Coro2b | coronin, actin binding protein, 2B | 0.013 | ||
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.012 | ||
| Ddn | dendrin | 0.012 | ||
| Znf498 | zinc finger protein 498 | 0.012 | ||
| Hand2 | heart and neural crest derivatives expressed 2 | 0.012 | ||
| Kcnq1 | potassium voltage-gated channel, KQT-like subfamily, member 1 | 0.012 | Human | |
| Shc2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.012 | ||
| Hhatl | hedgehog acyltransferase-like | 0.012 | ||
| Tmem38a | transmembrane protein 38a | 0.012 | ||
| Mcpt4 | mast cell protease 4 | 0.012 | ||
| Dio1 | deiodinase, iodothyronine, type I | 0.012 | ||
| Acads | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 0.012 | ||
| Gck | glucokinase | 0.012 | ||
| Tmem101 | transmembrane protein 101 | 0.011 | ||
| Dhrs7c | dehydrogenase/reductase (SDR family) member 7C | 0.011 | ||
| Hap1 | huntingtin-associated protein 1 | 0.011 | ||
| Slc5a2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 0.011 | ||
| Prl3d1 | Prolactin family 3, subfamily d, member 1 | 0.011 | ||
| Rps6ka2 | ribosomal protein S6 kinase polypeptide 2 | 0.011 | ||
| Irs3 | insulin receptor substrate 3 | 0.011 | ||
| Cav3 | caveolin 3 | 0.011 | ||
| Ucp3 | uncoupling protein 3 (mitochondrial, proton carrier) | 0.011 | ||
| Olr337 | olfactory receptor 337 | 0.011 | ||
| Tle2 | transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) | 0.011 | ||
| Taok2 | TAO kinase 2 | 0.011 | ||
| Znf575 | zinc finger protein 575 | 0.010 | ||
| Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.010 | ||
| Myl3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 0.010 |